Proton Pump Inhibitors: all 885 studies that test it
Page 8 of 9. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.
- Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer ProphylaxisTerminatedNCT00839488Phase 4
- Pantoprazole Sodium 40 mg DR Tablets Under Non-Fasting ConditionsCompletedNCT00835393Phase 1
- Effect of Helicobacter Pylori Treatment on Idiopathic Central Serous Chorioretinopathy (ICSCR)CompletedNCT00817245Phase 1/2
- Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 MutationStatus unknownNCT00789061Phase 2/3
- Study Using Esomeprazole as a Diagnostic Test for GERD in Patients With NCCPCompletedNCT00786695Not applicable
- Effect of Eradication of Helicobacter Pylori on the Dyspeptic SymptomsCompletedNCT00772837Not applicable
- Longitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal RefluxWithdrawnNCT00771706Phase 3
- Phase I Study to Evaluate Bioavailability of Naproxen as PN400 Compared to Naproxen as Proxen S and Naprosyn ECompletedNCT00761501Phase 1
- A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, InclusiveCompletedNCT00747695Phase 1
- A Study of Single and Multiple Doses of Rabeprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Months Old, InclusiveCompletedNCT00747526Phase 1
- Intravenous (IV) Pantoprazole for Gastroesophageal Reflux Disease (GERD) in Neonates and InfantsCompletedNCT00744419Phase 1
- Intravenous Proton Pump Inhibitor for Peptic Ulcer BleedingCompletedNCT00731601Phase 4
- Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected PatientsCompletedNCT00723502Phase 2
- Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus ControlWithdrawnNCT00713947Phase 4
- High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic TreatmentStatus unknownNCT00709046Not applicable
- Efficacy/Safety of Lansoprazole in Patients With Frequent Nighttime HeartburnCompletedNCT00701259Phase 3
- Influence of Pantoprazole on Human Myocardial Contractility at Patients With Congestive Heart FailureWithdrawnNCT00699361Phase 3
- Study Evaluating the Bioavailability of Naproxen 375 mg in Two FormulationsCompletedNCT00692055Phase 1
- Study Comparing a Fixed-Dose Capsule of Esomeprazole 40mg and LDA 325mg With Free CombinationCompletedNCT00688428Phase 1
- Pharmacokinetic Study of Esomeprazole Magnesium in Patients 1 to 11 Years-Old With Endoscopically-Proven Gastroesophageal Reflux Disease (GERD)CompletedNCT00687245Phase 1
- Drug Interaction Study Between AZD3355 and NexiumCompletedNCT00684190Phase 1
- Prevention of Gastrointestinal Bleeding in Patients With Severe Ischemic Heart DiseaseCompletedNCT00683111Phase 4
- A Comparative Study of Proton-pump Inhibitor Tests for Chinese Reflux Patients in Relation to the CYP2C19 GenotypesCompletedNCT00681005Not applicable
- Study Evaluating the Effect of Food on the Bioavailability of PN400 ComponentsCompletedNCT00676442Phase 1
- Drug-Drug Interaction Study of Esomeprazole (D961H) Capsule and Loxoprofen Tablet After Repeated Oral Administration in Japanese MalesCompletedNCT00676117Phase 1
- Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD.CompletedNCT00674245Phase 2/3
- Study Evaluating the Bioavailability of Naproxen 500 mg in Three FormulationsCompletedNCT00665743Phase 1
- Lansoprazole Versus Mosapride for Functional DyspepsiaCompletedNCT00663897Phase 4
- Fed Study of Rabeprazole Sodium Tablets 20 mg and Aciphex® Tablets 20 mgCompletedNCT00649493Phase 1
- Multicenter, Randomized, Double-Blind, Double-Dummy, Parallel-Group Comparison of the Remission Rates of Once Daily Treatment With Esomeprazole 20mg and Lansoprazole 15mg for 6 Months in Patients Whose EE Has Been HealedCompletedNCT00644735Phase 4
- A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive EsophagitisCompletedNCT00641602Phase 4
- Quality of Life Validation in LaryngitisCompletedNCT00641264Phase 4
- Randomized Double-Blind Clinical Trial of Rebamipide vs Esomeprazole in the Treatment of NSAID-induced GastropathyCompletedNCT00641004Phase 4
- Barrett's Esophagus - 315 - 3 Way Cross OverCompletedNCT00637988Phase 4
- Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)CompletedNCT00637845Phase 4
- Barrett's Esophagus - 315 - 3 Way Cross-OverCompletedNCT00637559Phase 4
- Open, Randomized, Two Way Crossover 40mg, Orally and IntravenouslyCompletedNCT00635414Phase 4
- A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is ContinuedCompletedNCT00633672Phase 3
- A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued in Subjects in the US OnlyCompletedNCT00633412Phase 3
- Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care UnitCompletedNCT00633035Phase 4
- Ulcer Prevention IICompletedNCT00629928Phase 3
- An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)CompletedNCT00629564Phase 4
- Prevention of Gastric UlcersCompletedNCT00629512Phase 3
- Adult Asthmatics and Acid RefluxCompletedNCT00628953Phase 2
- Chronic Posterior Laryngitis With Suspected Laryngopharyngeal RefluxCompletedNCT00628667Phase 4
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg qd and 40 mg qd to Placebo qd in Patients With Heartburn and Sleep Disturbances Associated With Gastroesophageal Reflux Disease (GERD)CompletedNCT00628342Phase 4
- A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)CompletedNCT00626535Phase 3
- Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and ivCompletedNCT00626262Phase 4
- Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)CompletedNCT00625495Phase 4
- A Randomized, Open-Label, Comparative 3-Way Treatment Crossover Study of 24-Hour Intragastric pH Profile of Once Daily Oral Administration of Esomeprazole 40mg, Lansoprazole 30mg, and Pantoprazole 40mg at Steady State in NSAID-Using PatientsCompletedNCT00625274Phase 4
- Use Of Esomeprazole In Postoperative Bariatric Surgery Patients Users And Non-Users Of Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)CompletedNCT00608712Phase 4
- vMII for Measurement of Oesophageal Bolus Transport and RefluxTerminatedNCT00604942Not applicable
- Placebo-Controlled Crossover Study for the Investigation of the Effect of Pantoprazole on Cardiac ContractilityCompletedNCT00600041Phase 1
- PK Study to Evaluate Esomeprazole Plasma Levels Following Administration of PN 400CompletedNCT00599404Phase 1
- Gastric pH in Critically Ill PatientsCompletedNCT00590928Phase 4
- Study to Assess Management Strategies for the Use of Esomeprazole (Nexium) in Helicobacter Pylori Infected PatientsCompletedNCT00574925Phase 4
- Trial of Oral Versus Intravenous Proton Pump Inhibitor on Intragastric pH in Patients With Bleeding UlcersCompletedNCT00573924Not applicable
- Effect of Acid Suppression With Esomeprazole on Vocal Cord GranulomasWithdrawnNCT00567658Phase 3
- In Vivo Quantification of Dental Demineralisation Using OCT With and Without EsomeprazoleCompletedNCT00564330Phase 1/2
- A Study of MK-8033 in Patients With Advanced Solid Tumors (MK-8033-001)CompletedNCT00559182Phase 1
- Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms.CompletedNCT00553449Phase 3
- The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERDStatus unknownNCT00539786Not applicable
- Omeprazole and Reflux Disease - Improvement of Clinical Outcome by Genotype-adjusted DosingTerminatedNCT00537732Phase 4
- PPI-Rebound-Trial. A Study of the Clinical Relevance of the Acid Rebound PhenomenaStatus unknownNCT00526006Phase 4
- Quadruple Therapy for Triple Therapy Resistant Helicobacter Pylori InfectionCompletedNCT00520949Not applicable
- Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic UlcersCompletedNCT00519519Phase 3
- A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac Chest Pain - a Randomized Double-blind Placebo-controlled StudyStatus unknownNCT00517270Not applicable
- Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese PatientsCompletedNCT00517114Not applicable
- The Use of Proton Pump Inhibitor for the Treatment of Non-erosive Gastro-oesophageal Reflux Disease in Chinese PopulationStatus unknownNCT00516971Not applicable
- Helicobacter Pylori and Iron Deficiency: Prevalence of Association and Effect of TherapyWithdrawnNCT00475527Phase 4
- Phase 1 Pharmacokinetics of Intravenous Nexium in ChildrenCompletedNCT00474019Phase 1
- Preoperative Non-steroidal Anti-inflammatory Drugs(NSAID) to Colorectal Cancer PatientsCompletedNCT00473980Phase 4
- Esomeprazole and Gastric Emptying of BeerCompletedNCT00472550Phase 4
- Safety and Efficacy of Ilaprazole 5, 20 and 40 mg QD and Lansoprazole 30 mg QD on Healing of Erosive EsophagitisCompletedNCT00471094Phase 2
- Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic UlcerStatus unknownNCT00471029Phase 4
- Helicobacter Pylori Infection in Children With Chronic Idiopathic Thrombocytopenic PurpuraCompletedNCT00467571Phase 4
- Pharmacokinetic Study of Lansoprazole in Cystic FibrosisCompletedNCT00458614Phase 1
- Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori InfectionStatus unknownNCT00455806Phase 3
- Esomeprazole Treatment for Patients With Lymphocytic GastritisStatus unknownNCT00455754Phase 3
- The CONQUEST-Study. Evaluation of Clinical Endpoints for Treatment-induced Changes in GERD-related Symptoms (BY1023/NL511)TerminatedNCT00449813Phase 4
- Effect of a Proton Pump Inhibitor on Gleevec® in Healthy VolunteersCompletedNCT00446004Phase 1
- Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid SuppressionTerminatedNCT00444236Phase 1
- Total Antioxidant Effects of Esomeprazole in Dyspeptic Patients Receiving Non-steroidal Anti-inflammatory DrugsWithdrawnNCT00443963Phase 4
- A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy SubjectsCompletedNCT00443170Phase 1
- Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies (Extension)WithdrawnNCT00442741Phase 1
- An Open-label, Exploratory Trial to Assess Gastric Acid Control in Critically Ill Subjects Receiving NexiumCompletedNCT00428701Phase 4
- Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced MalignanciesCompletedNCT00420615Phase 1
- Evaluation of 24-Hour Intragastric pH Using Esomeprazole, Lansoprazole, and Pantoprazole in Hispanic Patients With GERDCompletedNCT00410592Phase 4
- A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.CompletedNCT00405119Phase 2
- Efficacy and Safety Study of Esomeprazole vs Omeprazole to Treat Acute Non-Variceal Upper Gastrointestinal BleedingCompletedNCT00402259Phase 3
- Examine National Characteristics & Outcome Measures of GERD Patients Using the PPI Acid Suppression Symptom (PASS) Test for ResponseCompletedNCT00392002Phase 4
- Efficacy/Safety of Lansoprazole in Patients With Frequent HeartburnCompletedNCT00390390Phase 3
- Efficacy/Safety of Lansoprazole in Patients With Frequent HeartburnCompletedNCT00389948Phase 3
- PPI Sequencing StudyCompletedNCT00384592Phase 4
- Study Comparing 2 Different Formulations of Pantoprazole in Healthy Adults.CompletedNCT00383916Phase 1
- A Study to Monitor Intragastric pH in Patients Taking Rabeprazole vs. Patients Taking PantoprazoleCompletedNCT00378287Phase 1
- Study Evaluating Pantoprazole in Adolescents With GERDCompletedNCT00367614Phase 3
- Preventing Recurrent Ulcer Bleeding in Arthritis Patients Using Esomeprazole Plus CelecoxibCompletedNCT00365313Phase 3
- Tongue Exercises and Reflux Therapy for Upper Airway Resistance SyndromeWithdrawnNCT00364481Phase 1
- Study of Long-Term Use of Proton-Pump-Inhibitors in General PracticeStatus unknownNCT00363701Phase 4