An interventional study of Esomeprazole 20mg once daily in Gastroesophageal Reflux, sponsored by Hospital Authority, Hong Kong. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2010-07-07.
Sponsored by Hospital Authority, Hong Kong · Not applicable, Interventional, and Treatment
The purpose of this study is to evaluate the efficacy of proton pump inhibitor for the treatment of non-erosive reflux disease (NERD) in Chinese population. Studies from the western population have estimated a worldwide prevalence of gastro-oesophageal reflux disease from 10 to 20 %. Monthly symptoms of heartburn or acid regurgitation were found in 9.3% of subjects according to a population survey in Hong Kong. Most of these patients did not show evidence of erosive change during upper endoscopy. However, patients with NERD suffer from similar impairment of quality of life as patients with erosive oesophagitis and their symptoms are as severe as patients with erosive disease. Data on the use of proton pump inhibitor for the treatment of NERD in Chinese patients are scanty. Thus we want to perform a double-blind randomised placebo-controlled study to evaluate the efficacy of proton pump inhibitor for the treatment of NERD in Chinese population.
1,086 studies on the registry are indexed under Gastroesophageal Reflux; 187 are open to participants now.
This study's planned enrollment of 200 is above the median of 72 across 724 interventional studies indexed under Gastroesophageal Reflux.
Browse Gastroesophageal Reflux studies →Hospital Authority, Hong Kong is the lead sponsor of 79 studies on the registry; 5 are open to participants now.
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Exclusion Criteria:
Symptoms assessment, quality of life.
Time frame: 12 Weeks
Compliance
Time frame: 8 Weeks
Adverse effects
Time frame: 8 Weeks
This study is status unknown, as verified in Jul 2010. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Esomeprazole
Hospital Authority, Hong Kong