Proton Pump Inhibitors: all 885 studies that test it

Page 6 of 9. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.

• Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy SubjectsCompletedNCT02334501Phase 1
• A Pilot Study To Investigate The Effect Of Concurrent Antacid Administration On The Bioavailability Of Six Experimental Formulations Of PalbociclibCompletedNCT02311946Phase 1
• Influence of CYP2C19 Polymorphism on PK/PD of OmeprazoleCompletedNCT02299687Phase 1
• Evaluation of CYP450 Activities in Diabetic Patients vs. Non-diabetic SubjectsCompletedNCT02291666Phase 4
• Re-Evaluating the Inhibition of Stress Erosions: Gastrointestinal Bleeding Prophylaxis In ICUCompletedNCT02290327Phase 3
• The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored TurbinateStatus unknownNCT02278081Phase 4
• Influence of Pantoprazole on the Pharmacokinetics of Fradafiban After Multiple Oral Doses of Lefradafiban in Healthy SubjectsCompletedNCT02264119Phase 1
• Influence of Pantoprazole on the Pharmacokinetics of Fradafiban After Multiple Oral Doses of Lefradafiban Over 5 Days in Healthy SubjectsCompletedNCT02264106Phase 1
• Study to Evaluate the Effect of Multiple Doses of BIRT 2584 XX Tablets on the Pharmacokinetic Parameters of Warfarin, Omeprazole, Caffeine, and Dextromethorphan in Healthy Male VolunteersCompletedNCT02256813Phase 1
• Pain After Endoscopic Submucosal DissectionCompletedNCT02254889Not applicable
• The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)CompletedNCT02254148Phase 1
• Study to Determine the Effects of Multiple-dose Omeprazole on the Single-dose Pharmacokinetics of Tipranavir (TPV) Coadministered With Ritonavir (RTV) in Healthy Adult VolunteersCompletedNCT02253875Phase 1
• A Phase 1 Study to Examine the Pharmacodynamics of Different AZD1722 FormulationsCompletedNCT02249936Phase 1
• Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy SubjectsCompletedNCT02249871Phase 1
• Anticoagulation Regiments in Patients With Prosthetic Heart Valve ThrombosisStatus unknownNCT02240953Not applicable
• A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized MalesCompletedNCT02220777Phase 1
• A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy VolunteersCompletedNCT02214433Phase 1
• Study of the Effects of Pantoprazole on Levels of Prescribed Psychiatric MedicationsWithdrawnNCT02213887Phase 4
• Bioavailability of Oral BIRB 796 BS Tablets With and Without Administration of Oral Pantoprazole in Healthy Male VolunteersCompletedNCT02209831Phase 1
• A Comparison of Efficacy of Intravenous Esomeprazole and Ranitidine Treatment of Dyspeptic PainCompletedNCT02197143Phase 4
• Effects of PQ912 on the Pharmacokinetics of Midazolam and OmeprazoleCompletedNCT02190708Phase 1
• BIBR 953 ZW in Healthy Elderly SubjectsCompletedNCT02173730Phase 1
• Bioavailability of BIBR 963 ZW After 50 mg of BIBR 1048 MS With and Without of Pantoprazole in Healthy SubjectsCompletedNCT02170896Phase 1
• Assessment of Safety, Pharmacokinetics and the Effect of BIBR 1048 MS on Coagulation Parameters in Healthy Volunteer SubjectsCompletedNCT02170740Phase 1
• Bioavailability of BIBR 953 ZW After Oral Administration of BIBR 1048 MS in Healthy SubjectsCompletedNCT02170636Phase 1
• Bioavailability of BIBR 953 ZW After Administration of BIBR 1048 MS in Healthy SubjectsCompletedNCT02170623Phase 1
• Bioavailability of BIBR 1048 MS With and Without Pantoprazole Under Influence of Food in Healthy SubjectsCompletedNCT02170610Phase 1
• The Effect of NSAIDs After a Rotator Cuff Repair Surgery.WithdrawnNCT02153177Phase 4
• The Use of Proton Pump Inhibitor on the Prevention of Gastric Cancer BleedingTerminatedNCT02150447Phase 3
• The Changes of Ryodoraku and HRV After PPI Treatment in GERD PatientsStatus unknownNCT02149914Not applicable
• Research of Efficient Use of Omeprazole in Combination With Domperidone in Gastroesophageal Reflux Disease of Mild to Moderate SeverityStatus unknownNCT02140073Phase 4
• Rebamipide in Combination With Esomeprazole in the Management of Asian Patients With Functional DyspepsiaStatus unknownNCT02134405Phase 4
• A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of IsavuconazoleCompletedNCT02128893Phase 1
• The Study of Eustachian Tube Dysfunction and Laryngopharyngeal RefluxWithdrawnNCT02123498Phase 4
• Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And FoodCompletedNCT02097329Phase 1
• Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT02085018Phase 2
• Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days TreatmentCompletedNCT02084420Phase 3
• Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective StudyCompletedNCT02081404Not applicable
• Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD)WithdrawnNCT02039869Not applicable
• "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-Status unknownNCT02028234Phase 4
• Effect of Proton Pump Inhibitors on Endothelial FunctionCompletedNCT02022280Phase 1
• A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck CancerWithdrawnNCT02013453Phase 2
• Quadruple and Phytomedicine-based Therapies in H. Pylori InfectionCompletedNCT02004197Phase 2/3
• Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Rabeprazole Sodium Delayed Release Tablets Under Fed ConditionsCompletedNCT01990586Phase 1
• Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Rabeprazole Sodium Delayed Release Tablets Under Fasted ConditionsCompletedNCT01990378Phase 1
• A Pharmacokinetics (PK) Study of the Effects Rabeprazole and Rifampin on Dabrafenib in Subjects With BRAF V600 Mutation Positive TumorsCompletedNCT01954043Phase 1
• Lansoprazole in Preterm Infants With Gastroesophageal Reflux (GER)CompletedNCT01946971Phase 1/2
• Drug-Drug Interaction Study With PF-05089771CompletedNCT01934569Phase 1
• Concomitant Therapy of H. PyloriStatus unknownNCT01922765Phase 4
• Prilosec Bioequivalence Study in Healthy VolunteersCompletedNCT01921920Phase 1
• Drug Interaction Study To Investigate The Potential Effect Of Proton Pump Inhibitor On The Pharmacokinetics Of Palbociclib (PD-0332991)CompletedNCT01918176Phase 1
• 15-day Sequential Therapy for Helicobacter Pylori Infection in KoreaCompletedNCT01887249Phase 4
• PPI for Prevention of Post-sphincterotomy BleedingCompletedNCT01873079Phase 3
• The Study to Evaluate Efficacy and Safety of Newrabell® Tab.(Rabeprazole Sodium) 10mg b.i.d in Refractory GERDCompletedNCT01860482Phase 4
• Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal RefluxCompletedNCT01854970Not applicable
• Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of ASA (Acetylsalicylic Acid) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fasting ConditionsCompletedNCT01847404Phase 1
• CYP2C19 Genotype Predictor of Gastric Acid SuppressionWithdrawnNCT01824199Early Phase 1
• Study to Evaluate the Pharmacokinetics, Pharmacodynamics and SafetyCompletedNCT01820143Phase 1
• Effects of Lansoprazole on Sitagliptin Glucose-lowering Ability in Healthy Males: a Randomised Crossover StudyCompletedNCT01820104Phase 1
• To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006)CompletedNCT01813552Phase 1
• Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSECStatus unknownNCT01795794Phase 4
• A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and OmeprazoleCompletedNCT01786382Phase 1
• Laryngomalacia StudyWithdrawnNCT01782560Phase 1
• Lansoprazole in Preterm Infants With RefluxCompletedNCT01778101Phase 2
• A Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetics of VismodegibCompletedNCT01772290Phase 1
• The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Patients With Existing Type 1 DiabetesWithdrawnNCT01762657Phase 3
• The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes PatientsWithdrawnNCT01762644Phase 3
• Quadruple Versus Sequential Therapy for Helicobacter Pylori EradicationCompletedNCT01760824Not applicable
• Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate CancerCompletedNCT01748500Phase 2
• Indomethacin Prophylaxis for Heterotopic Ossification After Surgical Treatment of Elbow TraumaStatus unknownNCT01744314Not applicable
• Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)Status unknownNCT01735227Phase 4
• Effect of Omeprazole on MetforminCompletedNCT01711320Phase 1
• A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting ConditionsCompletedNCT01710995Phase 1
• Clinical Study, Multicenter, Randomized With 2 Arms of Pantoprazole + Domperidone and Pantoprazole Isolated at the Gastroesophageal Reflux DiseaseWithdrawnNCT01710462Phase 3
• Effects of YF476 and Rabeprazole on Gastric FunctionCompletedNCT01699113Phase 1
• Pharmacokinetic/Pharmacodynamic Study of Ilaprazole to Evaluate the Effect of CYP Genetic PolymorphismCompletedNCT01688544Phase 1
• Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic PatientsCompletedNCT01670552Phase 3
• Management of Myocardial Injury After Noncardiac Surgery TrialCompletedNCT01661101Phase 3
• Optimal Dosing of Omeprazole in NeonatesCompletedNCT01657578Phase 2
• Bioequivalence Study of Pantoprazole Sodium 40 mg Delayed Release Tablets Fed StudyCompletedNCT01654718Not applicable
• Bioequivalence Study of Pantoprazole Sodium 40 mg Delayed Release Tablets Fasting StudyCompletedNCT01654705Not applicable
• Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest PainWithdrawnNCT01637571Phase 4
• The Efficacy of Pantoprazole Treatment in Patients With Functional DyspepsiaStatus unknownNCT01608750Phase 4
• Clarithromycin-based Triple Therapy for 14 Days Versus Sequential Therapy 10 Days in the First Line TherapyStatus unknownNCT01607918Phase 4
• Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy VolunteersCompletedNCT01599858Phase 1
• Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid TumorsCompletedNCT01596647Phase 1
• The Efficacy of Double Doses of Oral Esomeprazole in Preventing Rebleeding for Patients With Bleeding Peptic UlcersCompletedNCT01591083Phase 4
• The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated OphthalmopathyCompletedNCT01579539Phase 3
• Increased Re-eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Triple TherapyStatus unknownNCT01572597Phase 4
• Drug Drug Interaction Study Of Crizotinib With Esomeprazole.CompletedNCT01549574Phase 1
• 5 Day Concomitant Versus 10 Day Sequential Therapy for Eradication of H. Pylori InfectionCompletedNCT01544517Phase 3
• Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of VandetanibCompletedNCT01539655Phase 1
• Comparison of the Efficacy of Levofloxacin-based Sequential Therapy and Triple Therapy as Second Line TherapyStatus unknownNCT01537055Phase 4
• Proton Pump Inhibitors in the Prevention of Iron Reaccumulation in Patient With Hereditary HemochromatosisStatus unknownNCT01524757Not applicable
• Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer SubjectsCompletedNCT01517399Phase 1
• New Dual Therapy for Primary Treatment of Helicobacter Pylori Infection：a Pilot StudyCompletedNCT01513785Phase 2
• Efficacy Study of Ilaprazole to Treat Erosive EsophgitisCompletedNCT01509261Phase 3
• Helicobacter Eradication Aspirin TrialCompletedNCT01506986Phase 4
• Efficacy of TAK-438, Amoxicillin and Clarithromycin in the First Line Eradication of H. PyloriCompletedNCT01505127Phase 3
• Magnesium Pantoprazole 20mg b.i.d. vs Magnesium Pantoprazole 40mg q.d. on Intragastric Acid InhibitionWithdrawnNCT01499693Phase 3

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