Proton Pump Inhibitors: all 885 studies that test it

Page 4 of 9. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.

• Assessment of the Effect of Omeprazole on Vicagrel in Healthy SubjectsStatus unknownNCT05651074Phase 1
• Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy ParticipantsCompletedNCT05635110Phase 1
• Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-TStatus unknownNCT05617651Phase 1
• HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPICompletedNCT05602597Phase 1
• Drug-drug Interaction Study of XZP-3621 TabletStatus unknownNCT05586568Phase 1
• Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in Healthy ParticipantsCompletedNCT05581992Phase 1
• HMPL-523 Food Effect and Proton Pump Inhibitor StudyCompletedNCT05571787Phase 1
• Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Ilaprazole and AceclofenacCompletedNCT05558150Phase 1
• Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-TCompletedNCT05509543Phase 1
• A Study in Healthy Men to Test How Esomeprazole Influences the Amount of BI 1819479 in the BloodCompletedNCT05467475Phase 1
• Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female VolunteersCompletedNCT05438303Phase 1
• Proton Pump Inhibitors Effects on Dyspepsia During Ramadan FastingCompletedNCT05287633Phase 1/2
• Endoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.CompletedNCT05267613Phase 3
• Biomarkers for Prediction of Analgesic Efficacy in Knee OA.CompletedNCT05256342Not applicable
• A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy SubjectsCompletedNCT05254548Phase 1
• Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and IlaprazoleCompletedNCT05237297Phase 1
• 14-day PCAB-based High-dose Dual Therapy and14-day PCAB-based Triple Therapy vs 14-day PPI-based Reverse Hybrid TherapyStatus unknownNCT05191888Phase 4
• Eradication Efficacy and Safety of Two Rescue Treatments for Helicobacter Pylori InfectionStatus unknownNCT05176821Not applicable
• A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy AdultsCompletedNCT05109390Phase 1
• A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008CompletedNCT05050188Phase 1
• Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)CompletedNCT05038969Phase 1
• The Effect of a Plant Protein Isolate on Muscle Protein Synthesis in Humans at Rest and After Resistance ExerciseCompletedNCT05020808Not applicable
• Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori InfectionStatus unknownNCT04991584Not applicable
• A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of AdavosertibTerminatedNCT04959266Phase 1
• High Dose Omeprazole in Patients With Pancreatic CancerTerminatedNCT04930991Early Phase 1
• A Study to Evaluate the One-way Interaction of Calcium Carbonate, Omeprazole, or Rifampin on ACP-196CompletedNCT04914936Phase 1
• Bioequivalence Study of DelanzoᵀᴹDR 60mg (Dexlansoprazole) Capsule With Dexilant® 60mg (Dexlansoprazole) Capsule in Healthy Pakistani Subjects.CompletedNCT04877834Phase 1
• A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With OmeprazoleCompletedNCT04876807Phase 1
• The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast CancerCompletedNCT04874935Phase 3
• Comparison of Efficacy of Triple Regimen Based on Clarithromycin VS Metronidazole in ChildrenStatus unknownNCT04721704Not applicable
• A Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of YPI 011 to Rabeprazole in Healthy Adult SubjectsCompletedNCT04703868Phase 1
• The Effect of PPI in Preventing Gastroesophageal Reflux Disease of SeafarersStatus unknownNCT04696783Phase 3
• The DDI Study Had Been Designed to Investigate the Effect of SHR3680 on the Pharmacokinetics of Midazolam, S-Warfarin and OmeprazoleCompletedNCT04676035Phase 1
• Response to Oral Lansoprazole of Inorganic Pyrophosphate Levels in Patients With Grönblad-Stranberg Disease (Pseudoxanthoma Elasticum)Status unknownNCT04660461Phase 4
• A Study to Compare PK, PD and Safety of the AD-214-02 and RabeprazoleCompletedNCT04622358Phase 1
• Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori InfectionCompletedNCT04621487Not applicable
• Comparing Different Regimens for Eradication of Helicobacter Pylori in KuwaitCompletedNCT04617613Phase 4
• Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy VolunteersCompletedNCT04568772Phase 1
• A Study to Assess the Effect of Food Intake and Drug-drug Interactions of E7090 When Co-administered With Rabeprazole or Rifampin in Healthy ParticipantsCompletedNCT04565574Phase 1
• Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux EsophagitisCompletedNCT04531475Phase 2
• Assessment and Management of Chronic Dyspepsia in Eastern UgandaCompletedNCT04525664Early Phase 1
• A Study to Compare PK, PD and Safety of the AD-214 10/600mg and RabeprazoleCompletedNCT04494243Phase 1
• A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy ParticipantsCompletedNCT04489797Phase 1
• A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole)CompletedNCT04468815Phase 1
• Intravenous Triple Therapy in the Treatment of Helicobacter Pylori Infection and Related Complications Caused by Active Peptic Ulcer DiseaseStatus unknownNCT04432233Phase 4
• PPI Therapy Impact on GERD After Sleeve GastrectomyStatus unknownNCT04400136Early Phase 1
• Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult SubjectsCompletedNCT04368585Phase 1
• Prospective Randomised Trial of First and Second Line Treatments of RCT of First and Second Line H Pylori Treatments in SloveniaStatus unknownNCT04359966Not applicable
• Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial.TerminatedNCT04333407Not applicable
• On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.CompletedNCT04329000Not applicable
• Safety to Evaluate the Efficacy and Safety of HIP1601 in Patients With Non Erosive Reflux DiseaseCompletedNCT04325620Phase 3
• Food-effect on PK and PD of Single Oral Dose of HIP1601 in Healthy SubjectsCompletedNCT04204629Phase 1
• Assessment of Gastric pH Changes Induced by Ascorbic Acid TabletsCompletedNCT04199624Phase 1
• Oral Omeprazole in Bleeding Peptic UlcerStatus unknownNCT04170270Early Phase 1
• Argon Plasma Coagulation for Barrett's EsophagusCompletedNCT04154748Not applicable
• Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)Active, not recruitingNCT04149470Phase 4
• Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver CirrhosisTerminatedNCT04140591Phase 2/3
• Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult SubjectsCompletedNCT04138836Phase 1
• The Epidemiology and Optimal Treatment of Helicobacter Pylori in MyanmarCompletedNCT04132479Phase 4
• A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881CompletedNCT04128787Phase 1
• Effect of Omeprazole on PK of Fluzoparib in Healthy Male SubjectsCompletedNCT04108676Phase 1
• A Comparison of High-dose Dual Therapy and Half-dose Clarithromycin-containing Bismuth Quadruple Therapy for H.P Eradication in Elderly PatientsStatus unknownNCT04101708Phase 4
• Efficacy and Safety of HIP1601 CapsuleCompletedNCT04080726Phase 3
• Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function TestStatus unknownNCT04022837Phase 2
• Empirical vs Tailored Therapy for H. Pylori InfectionStatus unknownNCT04006340Not applicable
• The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee ArthroplastyCompletedNCT04003350Not applicable
• Treatment Response of High-dose and Standard-dose Rabeprazole for Extra-esophageal Reflux.CompletedNCT04001400Phase 3
• A Study to Compare PK, PD and Safety of the AD-206 and EsomeprazoleCompletedNCT03980756Phase 1
• Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal BleedingCompletedNCT03980496Phase 4
• Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)CompletedNCT03979989Phase 1
• A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy ParticipantsCompletedNCT03979248Phase 1
• Pantoprazole Prophylaxis Against Delayed CINV for Patients Receiving Breast Cancer ChemotherapyCompletedNCT03948477Phase 2
• A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy ParticipantsCompletedNCT03936374Phase 1
• Effect of Daily Use Proton Pump Inhibitors for One Month on Kidney FunctionStatus unknownNCT03910647Phase 2
• Proton Pump Inhibitor Preventing Upper Gastrointestinal Injury In Patients On Dual Antiplatelet Therapy After CABGActive, not recruitingNCT03908593Phase 4
• Phase I Study of Continuous Administration of Salvianolic Acid A TabletStatus unknownNCT03908242Phase 1
• Food-effect on PK and PD of Single Oral Dose of HIP1601 in Healthy Male SubjectsCompletedNCT03882112Phase 1
• Dexlansoprazole MR-Based Concomitant Quadruple TherapyCompletedNCT03829150Not applicable
• Esomeprazole or Pantoprazole in Renal TransplantationCompletedNCT03812419Not applicable
• Daily Four Times or Two Times Usage of PPI and Amoxicillin for the First or Second Line H. Pylori EradicationStatus unknownNCT03802318Not applicable
• Effect of Food on Pharmacokinetics of Salvianolic Acid A in Healthy SubjectsStatus unknownNCT03791463Phase 1
• Phase I Single-dose Escalation Clinical Trial of Salvianolic Acid A TabletsStatus unknownNCT03791125Phase 1
• Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of VadadustatCompletedNCT03789032Phase 1
• EoE RCT Fluticasone and Omeprazole vs Fluticasone AloneStatus unknownNCT03781596Phase 4
• Efficacies of Two Bismuth Quadruple Therapies in the Second-line Treatment of H Pylori InfectionCompletedNCT03779087Not applicable
• Analysis of the Impact of Helicobacter Pylori on Salivary Microbiome in AdultsStatus unknownNCT03730766Phase 4
• Esomeprazole With Sildenafil Citrate in Women With Early-onset PreeclampsiaStatus unknownNCT03724838Not applicable
• Esomeprazole for the Prevention of PreeclampsiaStatus unknownNCT03717740Phase 3
• Metformin and Esomeprazole in Treatment of Early Onset PreeclampsiaStatus unknownNCT03717701Not applicable
• Drug Interaction Study of CT1812 in Healthy VolunteersCompletedNCT03716427Phase 1
• AZD4635 Relative Bioavailability StudyCompletedNCT03710434Phase 1
• Tailored Therapy for Helicobacter Pylori Treatment in Patients With Penicillin AllergyCompletedNCT03708848Phase 4
• The Effect of Esomeprazole on Type 2 DiabetesCompletedNCT03598738Not applicable
• Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic SclerosisCompletedNCT03561233Phase 1
• Genotypic Resistance Guided Therapy for Refractory H. Pylori InfectionStatus unknownNCT03555526Phase 4
• PPI and Microbiome in Healthy Volunteers and Functional DyspepsiaCompletedNCT03545243Phase 4
• Intraluminal Metronidazole Powder Monotherapy for Helicobacter Pylori InfectionCompletedNCT03524833Phase 4
• Intraluminal Amoxicillin Powder Monotherapy for Helicobacter Pylori InfectionCompletedNCT03521726Phase 4
• A Unique Regimen for Treatment of Helicobacter Pylori InfectionStatus unknownNCT03491995Phase 3
• PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese VolunteersCompletedNCT03488186Phase 1

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