Proton Pump Inhibitors: all 885 studies that test it

Page 2 of 9. Open to participants first (51), then studies with results posted, then the rest; newest registration first within each.

• PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric SubjectsTerminatedNCT02401035Phase 4Results posted
• A Study to Evaluate the Effect of Increased Stomach pH on Evacetrapib in Healthy ParticipantsCompletedNCT02365558Phase 1Results posted
• Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori InfectionCompletedNCT02359435Not applicableResults posted
• Dexlansoprazole in Asian Participants With Gastroesophageal Reflux DiseaseCompletedNCT02351960Phase 4Results posted
• Optimal Dose of Proton Pump Inhibitors Following an Upper Gastrointestinal BleedTerminatedNCT02235311Not applicableResults posted
• PK Study With Pantoprazole in Obese Children and AdolescentsCompletedNCT02186652Phase 1Results posted
• Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency AblationTerminatedNCT02162758Phase 2Results posted
• Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill PatientsCompletedNCT02157376Phase 3Results posted
• A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease PatientsCompletedNCT02135107Phase 3Results posted
• Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating TabletsCompletedNCT02096458Phase 1Results posted
• Bioavailability, Safety, and Pharmacodynamics of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets in Healthy ParticipantsCompletedNCT02064907Phase 1Results posted
• Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of Vonoprazan (TAK-438)CompletedNCT02037477Phase 3Results posted
• A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of Alectinib (RO5424802) in Healthy Volunteers.CompletedNCT02023125Phase 1Results posted
• Effect of Acid Suppression Medication on Pediatric MicrobiomeTerminatedNCT02016820Not applicableResults posted
• Effect of Proton Pump Inhibitors on CF Pulmonary ExacerbationsCompletedNCT01983774Phase 2Results posted
• Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese SubjectsTerminatedNCT01983566Phase 1Results posted
• A Study of Baricitinib and Omeprazole in Healthy ParticipantsCompletedNCT01925144Phase 1Results posted
• Effects of Gastric Acid on Colonic MicrobiomeCompletedNCT01901276Phase 4Results posted
• Ranitidin Versus Omeprazole in Patients Taking ClopidogrelCompletedNCT01896557Phase 4Results posted
• Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot StudyCompletedNCT01887743Phase 1Results posted
• Rate of Complete Symptom Relief, Prevention of Symptom Relapse: Grades A and B Esophagitis of Esomeprazole TherapyCompletedNCT01874535Phase 4Results posted
• Compliance With Antidepressant Medication in Treatment of Functional DyspepsiaCompletedNCT01851863Phase 4Results posted
• Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma TherapyCompletedNCT01848457Phase 2Results posted
• Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of AlisertibCompletedNCT01844583Phase 1Results posted
• Influence of Pantoprazole on the Bioavailability of MMF and EC-MPSCompletedNCT01801280Phase 4Results posted
• Anti-reflux Control to Decrease Post Tonsillectomy PainTerminatedNCT01777854Phase 4Results posted
• Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy VolunteersCompletedNCT01766050Phase 4Results posted
• High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic UlcerCompletedNCT01757275Phase 3Results posted
• Comparison of Pantoprazole and Ranitidine in DyspepsiaCompletedNCT01737840Phase 4Results posted
• Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor TherapyCompletedNCT01710800Not applicableResults posted
• Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in AdolescentsCompletedNCT01642615Phase 2Results posted
• Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules in Treating Symptomatic Non-Erosive Gastroesophageal Reflux Disease in AdolescentsCompletedNCT01642602Phase 2Results posted
• Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)CompletedNCT01587885Phase 4Results posted
• Pantoprazole on Insulin Secretion in DiabetesCompletedNCT01541735Phase 2/3Results posted
• Structured Non-operative Treatment of Knee OsteoarthritisCompletedNCT01535001Not applicableResults posted
• A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial FibrillationCompletedNCT01493557Phase 4Results posted
• Phase III Study Comparing Zegerid® With Losec® for the Relief of Heartburn Associated With Gastroesophageal Reflux DiseaseCompletedNCT01493089Phase 3Results posted
• Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.CompletedNCT01477320Not applicableResults posted
• Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)CompletedNCT01472939Phase 2Results posted
• Proton Pump Inhibitors and Dysbiosis in CirrhosisCompletedNCT01458990Not applicableResults posted
• SSP-002358 Drug Interaction Study With OmeprazoleCompletedNCT01415349Phase 1Results posted
• Long-term Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01398410Phase 2/3Results posted
• Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01397448Phase 2/3Results posted
• To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving RabeprazoleCompletedNCT01397084Phase 4Results posted
• Efficacy of Esomeprazole in Patients With Frequent HeartburnCompletedNCT01370538Phase 3Results posted
• Efficacy of Esomeprazole in Patients With Frequent HeartburnCompletedNCT01370525Phase 3Results posted
• Clopidogrel Pharmacogenetics (PGX) Bench to BedsideCompletedNCT01341600Not applicableResults posted
• The Effects of Dexlansoprazole for the Treatment of Throat-Related RefluxTerminatedNCT01317472Not applicableResults posted
• Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With PantoprazoleCompletedNCT01281501Phase 4Results posted
• A Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cobimetinib in Healthy ParticipantsCompletedNCT01277718Phase 1Results posted
• To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving RabeprazoleCompletedNCT01249651Phase 4Results posted
• Effect of Dexlansoprazole on Bone HomeostasisCompletedNCT01216293Phase 1Results posted
• A Clinical Pharmacological Study of Rabeprazole Sodium in Japanese Healthy Adult Male Volunteers (Study E3810)CompletedNCT01202071Phase 2Results posted
• Combination Therapy With Sitagliptin and Lansoprazole to Restore Pancreatic Beta Cell Function in Recent-Onset Type 1 DiabetesCompletedNCT01155284Phase 2Results posted
• Viokase 16, Viokase16 Plus Nexium and Nexium AloneTerminatedNCT01142128Phase 1Results posted
• Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic UlcerCompletedNCT01138969Phase 2Results posted
• Safety and Efficacy of Lansoprazole in Patients With Reflux DiseaseCompletedNCT01135368Phase 4Results posted
• Assessment of Zegerid on Esophageal pH in Patients With Barrett's EsophagusTerminatedNCT01129778Not applicableResults posted
• Gastric pH and Anthocyanin AbsorptionCompletedNCT01122160Not applicableResults posted
• Esomeprazole Treatment Co-diagnosed Non Erosive Reflux Disease (NERD) and Chronic Gastritis PatientsCompletedNCT01119768Phase 4Results posted
• Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?CompletedNCT01093755Phase 4Results posted
• A Study of E3810 for Japanese Subjects With Functional Dyspepsia (SAMURAI Study: Suppression of Acid Milieu With Rabeprazole Improving Functional Dyspepsia ) (Study E3810-J081-204)CompletedNCT01089543Phase 2Results posted
• Pharmacodynamic Study Comparing the Effects of Two Different Forms of Omeprazole (P07812) (COMPLETED)CompletedNCT01077076Phase 3Results posted
• Comparative Efficacy & Safety Study of D961H Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With Low-dose AspirinCompletedNCT01069939Phase 3Results posted
• Pharmacological Study That Measures Omeprazole Effect on Aspirins Absorption in Healthy VolunteersCompletedNCT01061034Not applicableResults posted
• Lansoprazole 30 mg DR Capsule Fasting Replicate Sprinkle StudyCompletedNCT01046253Phase 1Results posted
• Lansoprazole 30 mg DR Capsule Replicate Food StudyCompletedNCT01046084Phase 1Results posted
• Lansoprazole 30 mg DR Capsule Fasting StudyCompletedNCT01045967Phase 1Results posted
• Study to Evaluate the Pharmacokinetics and Safety of Dexlansoprazole in Pediatric Subjects With Symptomatic Gastroesophageal Reflux DiseaseCompletedNCT01045096Phase 1Results posted
• Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of HeartburnCompletedNCT01037452Phase 2Results posted
• An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux EsophagitisCompletedNCT01008696Phase 4Results posted
• Study to Compare Gastric Inhibition of Two Proton Pump Inhibitors (CL2008-18)(P07815)(COMPLETED)CompletedNCT01005719Phase 3Results posted
• A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaCompletedNCT01001299Phase 1Results posted
• A Study to Evaluate the Effect of Famotidine and Omeprazole on MK0518 (Raltegravir) Pharmacokinetics in Human Immunodeficiency Virus (HIV)-Infected Patients (0518-054)CompletedNCT01000818Phase 1Results posted
• Safety and Efficacy of Rabeprazole in Infants With Gastroesophageal Erosive Reflux Disease (GERD)CompletedNCT00992589Phase 3Results posted
• A Study of the Effects of Multiple Doses of Dexlansoprazole, Lansoprazole, Omeprazole or Esomeprazole on the Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Participants.CompletedNCT00942175Phase 1Results posted
• Drug-Drug Interaction of Cladribine and Pantoprazole in Multiple Sclerosis SubjectsCompletedNCT00938366Phase 1Results posted
• Comparing the Efficacy, Safety, and Tolerability of Rabeprazole ER 50 mg With Placebo in Subjects With Symptomatic Gastroesophageal Reflux Disease (sGERD)CompletedNCT00911534Phase 3Results posted
• Comparison of Prilosec Over-the-counter (OTC)® Versus Prevacid® for Gastric Acid SuppressionCompletedNCT00903448Phase 4Results posted
• Fluticasone Versus Esomeprazole to Treat Eosinophilic EsophagitisCompletedNCT00895817Not applicableResults posted
• Open Label Safety Study of Enteric-Coated Spheroid Suspension in Infants Aged Less Than 12 Months With Presumed Gastroesophageal Reflux Disease (GERD)CompletedNCT00868296Phase 3Results posted
• Efficacy of Dexlansoprazole MR on Heartburn Control in Participants Previously Receiving Twice Daily Proton Pump Inhibitor TherapyCompletedNCT00847808Phase 3Results posted
• Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux DiseaseCompletedNCT00847210Phase 1Results posted
• Rabeprazole Extended Release 50 mg Versus Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)CompletedNCT00839306Phase 3Results posted
• Effect of High-dose Oral Rabeprazole on Recurrent Bleeding After the Endoscopic Treatment of Bleeding Peptic UlcersTerminatedNCT00838682Phase 4Results posted
• Rabeprazole Extended-Release 50 mg vs. Ranitidine 150 mg for Maintenance of Healed Erosive Gastroesophageal Reflux Disease (GERD)CompletedNCT00838526Phase 3Results posted
• Novel Therapy to Preserve Beta Cell Function in New Onset Type 1 DiabetesTerminatedNCT00837759Phase 2Results posted
• Pantoprazole Sodium 40 mg DR Tablets Under Fasting ConditionsCompletedNCT00835588Phase 1Results posted
• 13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)CompletedNCT00825630Phase 4Results posted
• Comparison of Prilosec OTC® Versus Zegerid® for Gastric Acid SuppressionCompletedNCT00808769Phase 4Results posted
• A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric PatientsCompletedNCT00787891Phase 3Results posted
• Efficacy and Safety of Lansoprazole on Gastric and Duodenal Ulcers in Patients Taking Nonsteroidal Anti-Inflammatory DrugsCompletedNCT00787254Phase 3Results posted
• Double-blind Comparative Study of E3810 Tablets (10 or 20 mg b.i.d.) to Evaluate Efficacy and Safety in Patients With Refractory Reflux EsophagitisCompletedNCT00770913Phase 2/3Results posted
• Incretin Effect and Use After Clinical Islet TransplantationCompletedNCT00768651Phase 2Results posted
• A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (Study CL2008-02)(P07814)(COMPLETED)CompletedNCT00765206Phase 3Results posted
• A Safety and Efficacy Study of Lansoprazole in Preventing Aspirin-Induced Gastric and Duodenal UlcersTerminatedNCT00762359Phase 3Results posted
• Efficacy of Esomeprazole for Non-Allergic Rhinitis: A Double-blind, Placebo Controlled TrialCompletedNCT00745849Not applicableResults posted
• A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI)CompletedNCT00734097Phase 4Results posted
• The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic EsophagitisCompletedNCT00728481Phase 2/3Results posted
• The Effect of Protein on Calcium Absorption and Gastric Acid ProductionCompletedNCT00719160Phase 4Results posted

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