Protein Kinase Inhibitors: all 15,766 studies that test it
Page 133 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.
- An Extension Study of Linifanib (ABT-869) in Subjects With Advanced or Metastatic Solid TumorsCompletedNCT01413893Phase 1
- Iodine I 131 and Pazopanib Hydrochloride in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer Previously Treated With Iodine I 131 That Cannot Be Removed By SurgeryCompletedNCT01413113Phase 1
- Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform NeurofibromasCompletedNCT01412892Phase 2
- A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's SarcomaTerminatedNCT01412515Phase 2
- Phase I Study of PI3(Phosphoinositol 3)-Kinase Inhibitor BAY80-6946 With Paclitaxel in Patients With Advanced CancerCompletedNCT01411410Phase 1
- TORI 104 Pre-Surgical DasatinibWithdrawnNCT01410708Phase 2
- Masitinib in Refractory Active Rheumatoid ArthritisTerminatedNCT01410695Phase 2/3
- Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic LeukemiaCompletedNCT01410513Phase 1
- Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR MutationsStatus unknownNCT01410214Phase 2
- Palliative Treatments for Patients With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT01409499Phase 4
- Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node MetastasisCompletedNCT01409200Phase 2
- Study of the Pharmacokinetics and Pharmacodynamics of Crystalline PX-866 Tablets and Amorphous PX-866 Capsules in Healthy VolunteersCompletedNCT01408316Phase 1
- Rotating Pazopanib and Everolimus to Avoid ResistanceCompletedNCT01408004Phase 2
- Erlotinib Versus Gemcitabine/Cisplatin as (Neo)Adjuvant Treatment in Non-small Cell Lung CancerStatus unknownNCT01407822Phase 2/3
- Study of Pazopanib, Paclitaxel, and Carboplatin in Patients With Advanced Solid TumorsTerminatedNCT01407562Phase 1
- Study of PWT33597 Mesylate in Subjects With Advanced MalignanciesCompletedNCT01407380Phase 1
- Nilotinib With Radiation for High Risk ChordomaCompletedNCT01407198Phase 1
- A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male SubjectsCompletedNCT01406132Phase 1
- Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to GefitinibTerminatedNCT01405846Phase 2
- Sorafenib in First-line Treatment of Advanced B Child Hepatocellular CarcinomaTerminatedNCT01405573Phase 3
- Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR MutationStatus unknownNCT01405079Phase 3
- Drug-drug Interaction Study With Metformin and ImatinibCompletedNCT01404715Phase 1
- Japanese BAY80-6946 Monotherapy Phase I StudyCompletedNCT01404390Phase 1
- Neo-adjuvant Temsirolimus in Patients With Advanced Renal Cell CarcinomaCompletedNCT01404104Not applicable
- A Study of Investigational SAR245409 in Patients With Certain Lymphoma or LeukemiaCompletedNCT01403636Phase 2
- Evaluation of Liposomal Curcumin in Healthy VolunteersCompletedNCT01403545Phase 1
- Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin LymphomaCompletedNCT01403415Phase 1
- Study of AEB071 (a Protein Kinase C Inhibitor) in Patients With CD79-mutant Diffuse Large B-Cell LymphomaTerminatedNCT01402440Phase 1
- Cytochrom p450 3A4 and 1A2 Phenotyping for the Individualization of Treatment With Sunitinib or Erlotinib in Cancer PatientsCompletedNCT01402089Phase 4
- Effect of Rifampin on the Pharmacokinetics of Linifanib in Subjects With Advanced or Metastatic Solid TumorsCompletedNCT01401933Phase 1
- Study of an Investigational Drug, ASP3026, in Patients With Solid TumorsCompletedNCT01401504Phase 1
- Efficacy of Nilotinib Versus Imatinib in Ph+ CML in Early CP Who Have a Suboptimal Molecular Response to ImatinibStatus unknownNCT01400074Phase 3
- Efficacy of Certican® in Combination With Myfortic® in RenalStatus unknownNCT01399242Phase 4
- Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell TransplantCompletedNCT01398501Phase 1
- Effects of Gastric pH on the Pharmacokinetics of DasatinibCompletedNCT01398046Phase 1
- GINECO-EN102b - BKM120 as Monotherapy in the Treatment of Initial or Recurrent Metastatic Endometrial CancerCompletedNCT01397877Phase 2
- Evaluation of KX2-391 in Elderly Subjects With Acute Myeloid Leukemia (AML)CompletedNCT01397799Phase 1
- Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced LeukemiasCompletedNCT01396499Phase 1
- A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare TumoursActive, not recruitingNCT01396408Phase 2
- Cyclophosphamide and Pulse Dexamethasone With Rapamycin or HydroxychloroquineCompletedNCT01396200Early Phase 1
- A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has SpreadCompletedNCT01395121Phase 2
- A Study to Test the Ability of and Safety of GSK2110183 in Treating Langerhans Cell HistiocytosisCompletedNCT01395004Phase 2
- PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade GliomaCompletedNCT01393912Phase 1
- Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid TumorsCompletedNCT01392924Phase 1
- Phase Ib Study of PI3(Phosphoinositol 3)-Kinase Inhibitor Copanlisib With MEK (Mitogen-activated Protein Kinase) Inhibitor Refametinib (BAY86-9766) in Patients With Advanced CancerCompletedNCT01392521Phase 1
- HYPAZ: Hypertension Induced by PazopanibTerminatedNCT01392352Phase 2
- Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)CompletedNCT01392235Phase 2
- Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid TumorsCompletedNCT01391533Phase 1
- A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML)CompletedNCT01390337Phase 1
- Efficacy and Safety of a Neoadjuvant Treatment in Pancreatic CancerCompletedNCT01389440Phase 2
- Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).CompletedNCT01389427Phase 1/2
- Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal CancerCompletedNCT01387880Phase 2
- A Study of BYL719 in Adult Patients With Advanced Solid MalignanciesCompletedNCT01387321Phase 1
- Study in Healthy Males to Assess the Bioavailability of 4 Different Fostamatinib TabletsCompletedNCT01387308Phase 1
- Study to Investigate the Absorption, Distribution, Metabolism and Elimination of [14C]GSK1120212CompletedNCT01387204Phase 1
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015KCompletedNCT01387087Phase 1
- Single Dose Study of [14C]-Labelled AMG 706 in Patients With Advanced Solid TumorsCompletedNCT01386866Phase 1
- Pazopanib, Docetaxel, Prednisone ProstateCompletedNCT01385228Phase 1
- Phase I Study of CUDC-101 With Cisplatin and Radiation in Subjects With Head & Neck CancerCompletedNCT01384799Phase 1
- Safety and Preliminary Efficacy of GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis PatientsCompletedNCT01384422Phase 2
- Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung CancerWithdrawnNCT01383668Phase 1
- Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal CancerCompletedNCT01383343Phase 1
- To Compare Relative Bioavailability of Two Clinical Formulations of Linifanib.CompletedNCT01381341Phase 1
- A Phase 3, Randomized, Double-Blinded, Placebo-Controlled Study of ARQ 197 Plus Erlotinib Versus Placebo Plus ErlotinibTerminatedNCT01377376Phase 3
- Pazopanib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaStatus unknownNCT01377298Phase 2
- A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal MelanomaStatus unknownNCT01377025Phase 2
- Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal CancerCompletedNCT01376453Phase 1
- Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT01375829Phase 1
- Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)CompletedNCT01374750Phase 2
- Bioequivalence And Food Effect Study Of Bosutinib In Healthy SubjectsCompletedNCT01374139Phase 1
- GSK1120212 Food-effect StudyCompletedNCT01371487Phase 1
- First International Randomized Study in Malignant Progressive Pheochromocytoma and ParagangliomaCompletedNCT01371201Phase 2
- MK-2206 in Recurrent Nasopharyngeal CarcinomaCompletedNCT01370070Phase 2
- Study of Oral AMN107 (Nilotinib) in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase Previously Enrolled to CAMN107A2109 TrialCompletedNCT01368523Phase 4
- A Study of ARRY-371797 in Patients With Osteoarthritis of the KneeCompletedNCT01366014Phase 2
- Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy VolunteersCompletedNCT01364987Phase 1
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015KCompletedNCT01364974Phase 1
- Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant TumorsCompletedNCT01364844Phase 1
- Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid MalignanciesActive, not recruitingNCT01364051Phase 1
- A Phase 1 Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Tivozanib in Healthy SubjectsCompletedNCT01363804Phase 1
- A Phase 1 Study to Evaluate The Effect of Ketoconazole on the Pharmacokinetics of Tivozanib in Healthy SubjectsCompletedNCT01363778Phase 1
- A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.CompletedNCT01363752Phase 4
- Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain MetastasisTerminatedNCT01363557Not applicable
- Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor PatientsCompletedNCT01363232Phase 1
- AZD6244 Hydrogen Sulfate for Children With Nervous System TumorsActive, not recruitingNCT01362803Phase 1/2
- TRICC-C (AIO-KRK-0111): BIBF 1120 Versus Placebo in Patients Receiving Oxaliplatin Plus Fluorouracil and Leucovorin (mFOLFOX6) for Advanced, Chemorefractory Metastatic Colorectal Cancer (mCRC)CompletedNCT01362361Phase 2
- Pilot Clinical Trial of Pazopanib in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or at Initial Diagnosis When no Intensive Treatment is PossibleCompletedNCT01361334Phase 2
- Gemcitabine and ON 01910.Na in Previously Untreated Metastatic Pancreatic CancerCompletedNCT01360853Phase 3
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or LymphomaCompletedNCT01359696Phase 1
- Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-upActive, not recruitingNCT01357772Phase 3
- Palliative Treatment of Hepatocellular Carcinoma in Patient With CHILD B CirrhosisCompletedNCT01357486Phase 2
- A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung CancerCompletedNCT01357395Phase 2
- Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT01357330Phase 1
- Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's LymphomaCompletedNCT01356173Phase 1
- Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy SubjectsCompletedNCT01355354Phase 1
- AZD1152 in Diffuse Large B-cell LymphomaCompletedNCT01354392Phase 1/2
- Efficacy and Safety of Induction Strategies Combined With Low Tacrolimus Exposure in Kidney Transplant Recipients Receiving Everolimus or Sodium MycophenolateCompletedNCT01354301Phase 4
- Open Label Phase 1 Study in Japan for Patient With Advanced Solid MalignanciesCompletedNCT01353781Phase 1
- Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.CompletedNCT01353625Phase 1
- Hepatocellular Carcinoma (HCC) Transarterial Chemoembolisation (TACE) +AxitinibCompletedNCT01352728Phase 2