Protease Inhibitors: all 1,856 studies that test it
Page 13 of 19. Open to participants first (69), then studies with results posted, then the rest; newest registration first within each.
- Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial HypertensionStatus unknownNCT02023450Early Phase 1
- A Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK2336805 Alone and With the Co-administration of TMC435 in Healthy Japanese Participants.CompletedNCT02018536Phase 1
- Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIVActive, not recruitingNCT02016924Phase 2/3
- Alpha1 Antitrypsin Aerosol Therapy in Cystic FibrosisTerminatedNCT02010411Phase 2
- Open Label Trial of PEG-IFN, RBV & TVR vs. PEG-IFN & RBV Alone in Tx of HCV-1 in HIV-1 Co-infected Patients (CHAT)CompletedNCT02006745Phase 3
- Phase II Study to Evaluate the Efficacy and Safety of Glassia® in Type-1 DiabetesCompletedNCT02005848Phase 2
- Phase I Ascending Multiple-Dose Study of BMS-986115 in Subjects With Advanced Solid TumorsTerminatedNCT01986218Phase 1
- Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)CompletedNCT01983241Phase 3
- UNITY 1: A Study of an Investigational Treatment Regimen of Daclatasvir (DCV) + Asunaprevir (ASV) + BMS-791325 in a Fixed Dose Combination (the DCV 3DAA (Direct Acting Antiviral) Regimen) for 12 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Genotype 1 Infection in Non-cirrhotic SubjectsCompletedNCT01979939Phase 3
- Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule FormulationsCompletedNCT01979484Phase 1
- Safety and Efficacy Study of a Triplet Combination of MLN9708, Lenalidomide and Dexamethasone in the Initial Management of Multiple Myeloma (IFM2013-06)CompletedNCT01936532Phase 2
- LAAM-HAART PET ImagingCompletedNCT01935830Early Phase 1
- Evaluation of the Efficacy and Safety Between Two Antiretroviral Regimens, in HIV-1-infected Treatment-naïve Subjects With Low CD4 CountsCompletedNCT01928407Phase 4
- A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial NeoplasiaWithdrawnNCT01925378Phase 2
- Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)CompletedNCT01919125Phase 1
- Drug-Drug Interaction Between IDX719, Simeprevir, TMC647055 and Ritonavir When Administered in Combination in Healthy Participants (MK-1894-007)CompletedNCT01907724Phase 1
- Bone Mineral Density Changes in HIV-positive Females With Osteopenia Switching to RaltegravirTerminatedNCT01902186Phase 4
- The Interaction of Two HIV Medications With Blood Clot Medications in Healthy VolunteersCompletedNCT01896622Phase 1
- Mechanism and Early Intervention Research on ALI During Emergence Surgery of Acute Stanford A Aortic DissectionStatus unknownNCT01894334Not applicable
- A Study of Drug-drug Interaction Between Ritonavir and TMC435350 in Healthy VolunteersCompletedNCT01891851Phase 1
- Study of the Pharmacokinetics and Safety of Asunaprevir in Patients With Kidney DiseaseCompletedNCT01886599Phase 1
- Interaction Between Etravirine or Darunavir/Ritonavir and Artemether / LumefantrineCompletedNCT01876966Phase 1
- Miravirsen in Combination With Telaprevir and Ribavirin in Null Responder to Pegylated-Interferon Alpha Plus Ribavirin Subjects With Chronic Hepatitis C Virus InfectionStatus unknownNCT01872936Phase 2
- Open Label Trial to Compare BI 207127 to Telaprevir in HCV PatientsWithdrawnNCT01858961Phase 3
- Samatasvir (IDX719) in Combinations With Simeprevir and/or TMC647055/Ritonavir With or Without Ribavirin for 12 Weeks in Participants With Chronic Hepatitis C Infection (MK-1894-005)CompletedNCT01852604Phase 2
- A Study of TMC435 Plus Pegylated Interferon Alfa-2a and Ribavirin in Participants With Chronic HCV InfectionCompletedNCT01846832Phase 3
- Interaction Between Paroxetine and TelaprevirTerminatedNCT01841502Phase 2
- An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Prader-Willi SyndromeCompletedNCT01818921Phase 2
- Pharmacokinetic Interactions Between Telaprevir and Un-boosted AtazanavirCompletedNCT01818856Phase 1
- To Evaluate the Effect of Ritonavir or Omeprazole on the Pharmacokinetics of Samatasvir (IDX719) in Healthy Participants (MK-1894-006)CompletedNCT01813552Phase 1
- Study to Evaluate Drug-Drug Interaction Between IDX719 and Simeprevir in Healthy Participants (MK-1894-004)CompletedNCT01813513Phase 1
- A Phase 4 Study to Evaluate Pharmacokinetics and Safety of Darunavir Along With Ritonavir in Healthy Male Japanese ParticipantsCompletedNCT01810887Phase 4
- A Pharmacokinetic Study to Assess the Effect of Food in Healthy Male Participants Receiving TMC435CompletedNCT01799603Phase 1
- Efficacy and Safety Evaluation of a Treatment Consisting of Peg Interferon Alfa + Ribavirin + Daclatasvir in HCV Genotype 1 and 4 Treatment naïve PatientsWithdrawnNCT01797848Phase 3
- Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With RibavirinCompletedNCT01795911Phase 2
- A Drug Interaction Study of the Effects of PPI-668 on the Pharmacokinetics of Midazolam and OmeprazoleCompletedNCT01786382Phase 1
- Nevirapine vs Ritonavir-boosted Lopinavir in ART Naive HIV-infected Adults in a Resource Limited SettingCompletedNCT01772940Phase 4
- Clinical Pharmacology Study of MP-424CompletedNCT01766167Phase 1
- Hepatitis C Virus Post-Exposure Prophylaxis for Health Care WorkersWithdrawnNCT01766115Phase 4
- A Study of Ritonavir-Boosted Danoprevir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients of Asian Origin With Chronic Hepatitis C Genotype 1 With or Without CirrhosisCompletedNCT01749150Phase 2
- A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.CompletedNCT01736761Phase 4
- Pilot Study to Assess the Efficacy of and Tolerance to a QUadruple Therapy to Treat HIV-HCV Coinfected Patients Previously Null RespondersCompletedNCT01725542Phase 2
- Efficacy and Safety Evaluation of a Regimen Consisting of Peginterferon Lambda-1a + Ribavirin + Daclatasvir (Lambda + RBV + DCV) in HCV Genotype 1b Treatment naïve Patients or Prior Relapsers to Peginterferon Alfa + Ribavirin (Alfa + RBV) TherapyCompletedNCT01718158Phase 3
- A Phase 3, Comparative Study of Asunaprevir and Daclatasvir Combination Therapy Versus Telaprevir Therapy in Japanese HCV SubjectsCompletedNCT01718145Phase 3
- A Study to Assess the Absolute Bioavailability and Pharmacokinetics of Simeprevir (TMC435) Administered as Single Oral Doses of TMC435 and an Intravenous Microdose of [3H]-TMC435 in Healthy Male PatientsCompletedNCT01707342Phase 1
- Early Access to Low-dose Ritonavir (TMC114/r) and Other Antiretrovirals (ARVs) for Treatment-naive or Early Treatment Experienced in HIV-1 PatientsCompletedNCT01702090Phase 4
- Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With RifampinTerminatedNCT01700790Phase 4
- A Pharmacokinetic Interaction Study Between TMC435, Atorvastatin and Simvastatin in Healthy ParticipantsCompletedNCT01689623Phase 1
- An Efficacy, Safety and Pharmacokinetics Study of Beloranib (ZGN-440 for Injectable Suspension) in Obese SubjectsCompletedNCT01666691Phase 2
- Long Term Treatment Effect of the Safety, Tolerability and Efficacy of AAT in Type 1 DiabetesCompletedNCT01661192Phase 2
- MLN9708 and Dexamethasone for High-Risk Smoldering Multiple MyelomaWithdrawnNCT01660997Phase 2
- Drug-drug Interaction Study Between Lopinavir/Ritonavir and IsavuconazoleCompletedNCT01660477Phase 1
- Eltrombopag/Boceprevir and Eltrombopag/Telaprevir Drug-Drug Interaction Study In Healthy Adult SubjectsCompletedNCT01657552Phase 1
- A Pharmacokinetic And Bioavailability Study of Intravenous Danoprevir in Healthy VolunteersCompletedNCT01654211Phase 1
- Drug Interaction Study to Assess the Effect of Co-Administered Miravirsen and Telaprevir in Healthy SubjectsCompletedNCT01646489Phase 1
- Ulinastatin Preventing Postoperative Hepatic Failure in Hepatocellular Carcinoma (HCC)CompletedNCT01643447Not applicable
- A Study of Ritonavir-Boosted Invirase (Saquinavir) in Treatment-Naïve HIV-1 Infected PatientsCompletedNCT01638650Phase 1
- Crossover Trial of the Effect of a High-Fat Meal on the PK of Oral CHR 2797 in Healthy Male SubjectsCompletedNCT01638442Phase 1
- Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)CompletedNCT01637558Phase 4
- A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and TelaprevirCompletedNCT01635829Phase 1
- Phase 2b Study of BMS-986094 and Daclatasvir, With or Without Ribavirin for the Treatment of Patients With Chronic Hepatitis CWithdrawnNCT01629732Phase 2
- ANNAPURNA: A Study of The Combination of RO5466731, RO5190591, Ritonavir and Copegus (Ribavirin) With or Without RO5024048 in Patients With Chronic Hepatitis C Who Are Either Treatment-Naïve or Have Previously Experienced a Null Response to Interferon-Based TreatmentCompletedNCT01628094Phase 2
- A Study to Assess the Bioequivalence of Darunavir When Co-Administrated With Cobicistat Under Fed and Fasted ConditionsCompletedNCT01619527Phase 1
- Safety and Efficacy Study of Pegylated Interferon Lambda With and Without Daclatasvir, Compared to Pegylated Interferon Alfa, Plus Ribavirin in Subjects With Hepatitis C Genotype 2 and 3CompletedNCT01616524Phase 3
- A Phase III Study of BI201335 in Treatment-naive and Prior Relapser Patients With Chronic Hepatitis C InfectionWithdrawnNCT01608737Phase 3
- Second-line Treatment of HIV-1 With Ritonavir Boosted Atazanavir or Darunavir With an Optimized NRTI BackboneWithdrawnNCT01605084Phase 3
- A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic ImpairmentCompletedNCT01600976Phase 1
- Atazanavir/r + Lamivudine Dual TherapyCompletedNCT01599364Phase 4
- Estimate the Effect of Telaprevir and Boceprevir on Maraviroc Pharmacokinetics in Healthy SubjectsCompletedNCT01597895Phase 1
- A Study of The Relative Bioavailability of Ritonavir-Boosted Danoprevir Fixed Dose Combination Tablets in Healthy VolunteersCompletedNCT01592318Phase 1
- A Study of Drug-Drug Interaction Between Danoprevir Coadministered With Low-Dose Ritonavir and Tenofovir Disoproxil Fumarate or AtazanavirCompletedNCT01592305Phase 1
- A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy VolunteersCompletedNCT01591850Phase 1
- A Study of Potential Drug-Drug Interaction Between Efavirenz and Danoprevir With Low Dose Ritonavir in Healthy VolunteersCompletedNCT01588002Phase 1
- The Mochudi Prevention Project ART ProtocolTerminatedNCT01583439Not applicable
- Pilot Simplification Study to Lopinavir/Ritonavir 800/200 mg Monotherapy Regimen Once DailyCompletedNCT01581853Phase 4
- Phase III Hallmark DUAL: ASV+DCV (Nulls/Partials, Intolerants/Ineligibles. Naives)CompletedNCT01581203Phase 3
- Efficacy of Racecadotril in Acute Watery Diarrhea in ChildrenCompletedNCT01577043Phase 4
- Phase III Hallmark QUAD: ASV+DCV+Peg+Rib (Nulls/Partials)CompletedNCT01573351Phase 3
- An Efficacy and Safety Study of Telaprevir in Patients With Genotype 1 Hepatitis C Infection After Liver TransplantationCompletedNCT01571583Phase 3
- A Study to Assess Bioavailability & Food Effect of Different Liquid and Capsule Formulations of TMC435.CompletedNCT01571570Phase 1
- Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or RifampinCompletedNCT01571414Phase 1
- A Study to Evaluate the Efficacy, Safety and Tolerability of TMC435 in Combination With PegIFN Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment-Naïve or Treatment-Experienced, Chronic Hepatitis C Virus Genotype-4 Infected PatientsCompletedNCT01567735Phase 3
- A Study to Evaluate the Effect of Boceprevir and Telaprevir on Dolutegravir Pharmacokinetics in Healthy Adult Subjects (ING115697).CompletedNCT01563328Phase 1
- Nelfinavir and Lenalidomide/Dexamethasone in Progressive Multiple MyelomaTerminatedNCT01555281Phase 1/2
- Efficacy and Safety of Odanacatib in Postmenopausal Women Previously Treated With Alendronate (MK-0822-050)WithdrawnNCT01552122Phase 3
- Evaluation of Hepatic Pharmacokinetics for Grazoprevir (MK-5172) in Participants With Chronic Hepatitis C (MK-5172-022)WithdrawnNCT01547312Phase 1
- A Study of Drug-Drug Interaction Between Danoprevir/Low-Dose Ritonavir and Raltegravir in Healthy VolunteersCompletedNCT01531647Phase 1
- Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin AloneCompletedNCT01529541Phase 3
- A Study to Efficacy and Safety of CWP-0403 in Type 2 Diabetes Mellitus PatientsCompletedNCT01529528Phase 3
- A Study to Evaluate the Safety, Tolerability, and PK in Healthy Volunteers and HCV Genotype 1 Infected PatientsCompletedNCT01523990Phase 1
- A Study of Drug-Drug Interaction Between Darunavir and Danoprevir Administered Together With Low-Dose Ritonavir in Healthy VolunteersCompletedNCT01519336Phase 1
- Ulinastatin's Anti-inflammatory Reaction in Cardiac SurgeryCompletedNCT01518569Phase 4
- A Drug-Drug Interaction Study Between Danoprevir/Low-Dose Ritonavir and Cyclosporine in Healthy VolunteersCompletedNCT01514968Phase 1
- An Efficacy and Safety Study of Telaprevir in Patients Infected With Both Chronic Hepatitis C Virus (HCV-1) and Human Immunodeficiency Virus (HIV-1)CompletedNCT01513941Phase 3
- Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron OverloadStatus unknownNCT01511848Phase 2/3
- Study of Hepatitis C Virus (HCV) Nonstructural Protein 5a (NS5A) Inhibitor IDX719 in Healthy and HCV-Infected Participants (MK-1894-001)CompletedNCT01508156Phase 1/2
- ZGN-440 (Beloranib for Subcutaneous Injection) for Treatment of ObesityCompletedNCT01507077Phase 1
- A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial EpilepsyTerminatedNCT01501383Phase 2
- Telaprevir Open-Label Study in Co-Infected PatientsCompletedNCT01500616Phase 3
- A Phase 3 Study in Combination With BMS-790052 and BMS-650032 in Japanese Hepatitis C Virus (HCV) PatientsCompletedNCT01497834Phase 3