Protease Inhibitors: all 1,856 studies that test it
Page 14 of 19. Open to participants first (69), then studies with results posted, then the rest; newest registration first within each.
- A Study in Healthy Female Participants Investigating the Effect of TMC435 on the Pharmacokinetics of the Synthetic Hormones of the Oral Contraceptive OvysmenCompletedNCT01486004Phase 1
- Safety Study of Nelfinavir + Cisplatin + Pelvic Radiation Therapy to Treat Cervical CancerCompletedNCT01485731Phase 1
- A Study of Ritonavir-Boosted Danoprevir and RO5024048 in Different Combinations in Null Responder or Treatment-Naïve Patients With Chronic Hepatitis C and Compensated CirrhosisCompletedNCT01483742Phase 2
- A Relative Bioavailability Study of Danoprevir and Ritonavir in Healthy VolunteersCompletedNCT01483729Phase 1
- A Study in Healthy Participants Investigating the Effect of TMC435 on the Pharmacokinetics of Immunosuppressants Cyclosporine and TacrolimusCompletedNCT01479881Phase 1
- Study to Compare the Pharmacokinetics Profiles of Four Racecadotril ProductsCompletedNCT01476683Phase 1
- Pharmacokinetics, Safety & Tolerability of Isotopologs of Atazanavir (ATV), With Pharmacokinetic Comparison to ReyatazCompletedNCT01458769Phase 1
- Study to Determine the Effectiveness and Safety of a Three Drug Antiviral Combination Therapy to Treat Hepatitis C Virus (HCV) Infected Patients Not Previously Treated With Currently Available MedicationsCompletedNCT01455090Phase 2
- Study to Evaluate the Safety, Pharmacokinetics and Tolerability of BMS-708163CompletedNCT01454115Phase 1
- A Phase 1 Study of PPI-668 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) Genotype 1CompletedNCT01448200Phase 1
- Radical Lung Radiotherapy Plus NelfinavirWithdrawnNCT01447589Phase 1/2
- A Study on Antiretroviral Therapy (ART) Naïve Patients On Different Regimens to Treat Hiv (NORTHIV)CompletedNCT01445223Phase 4
- A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid TumorsCompletedNCT01445106Phase 1
- GS-5885, GS-9451, Tegobuvir and Ribavirin (RBV) in Interferon Ineligible or Intolerant Subjects With Chronic Genotype 1a or 1b Hepatitis C Virus (HCV) InfectionCompletedNCT01434498Phase 2
- A Study to Evaluate the Effect of Danoprevir/Ritonavir on the Pharmacokinetics of Escitalopram and S-Demethylcitalopram in Healthy VolunteersCompletedNCT01418274Phase 1
- Peginterferon and Ribavirin, With or Without Telaprevir, for Genotype 1 Hepatitis C and IL28B CC PolymorphismWithdrawnNCT01415141Phase 4
- A Study of Danoprevir in Combination With Low-Dose Ritonavir in Healthy SubjectsCompletedNCT01398293Phase 1
- Safety and Efficacy of Inhaled Alpha-1 Antitrypsin in Preventing Bronchiolitis Obliterable Syndrome in Lung Transplant RecipientsStatus unknownNCT01394835Phase 2
- A Study to Evaluate The Effects of Two Different Meal Types, Omeprazole And Ranitidine On Danoprevir Pharmacokinetics When Coadministered With Ritonavir in Healthy VolunteersCompletedNCT01392755Phase 1
- A Study on the Interaction Between Danoprevir/Ritonavir and MethadoneCompletedNCT01389544Phase 1
- TMC435-TiDP16-C126 - Trial to Investigate the Effect of Severe Renal Impairment on the Pharmacokinetics and Safety of TMC435CompletedNCT01381835Phase 1
- Pharmacokinetics, Safety, Tolerability and Efficacy of Intravenous Doses of ZGN-433 in Obese Female VolunteersCompletedNCT01372761Phase 1
- Oral Antivirals (GS-5885, Tegobuvir, and/or GS-9451) With Peginterferon Alfa 2a and Ribavirin in Treatment Experienced Subjects With Chronic Genotype 1 Hepatitis C Virus InfectionCompletedNCT01371578Phase 2
- Two Clinical Trials to Evaluate Pharmacokinetics of Unboosted and Boosted Atazanavir Used Alone or Co-administered With Tenofovir DF in Healthy Korean and Caucasian Male VolunteersStatus unknownNCT01368783Phase 1
- Study to Evaluate the Safety and Tolerability of Weekly Intravenous (IV) Doses of BMS-906024 in Subjects With Acute T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic LymphomaCompletedNCT01363817Phase 1
- GS-5885 Alone or in Combination With GS-9451 With Peginterferon Alfa 2a and Ribavirin in Treatment Chronic Genotype 1 Hepatitis C VirusCompletedNCT01356160Phase 2
- GS 5885 Administered Concomitantly With GS-9451, Tegobuvir and Ribavirin (RBV) in Chronic Genotype 1 Hepatitis C Virus (HCV) InfectionCompletedNCT01353248Phase 2
- Pharmacokinetic Interaction Between Ritonavir and Prasugrel in Healthy VolunteersCompletedNCT01346800Phase 1
- TMC125IFD1001 - Drug-Drug Interaction of Etravirine With Telaprevir and TMC278 With Telaprevir.CompletedNCT01336829Phase 1
- A Open-label Study to Evaluate the Relative Bioavailability of Samatasvir (IDX184) and Food Effect in Healthy Male Participants (MK-2355-006)CompletedNCT01335607Phase 1
- Telaprevir in HIV-HCV Coinfected Patients Who Had Previously Failed a Peginterferon-Ribavirin RegimenCompletedNCT01332955Phase 2
- TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r)CompletedNCT01323257Phase 1
- A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 StudyCompletedNCT01323244Phase 3
- The Effects of Alpha-1 Antitrypsin (AAT) on the Progression of Type 1 DiabetesCompletedNCT01319331Phase 1
- Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With RibavirinCompletedNCT01309932Phase 2
- TMC114-TiDP3-C176 - A Study in Healthy Volunteers Investigating the Bioequivalence Between Two Commercially Available 400-mg Tablets to One New 800-mg Tablet of Darunavir (DRV) in the Presence of Low-dose Ritonavir Under Fed and Fasted ConditionsCompletedNCT01308658Phase 1
- TMC435-TiDP16-C116 - Relative Bioavailability and Food Effect StudyCompletedNCT01308606Phase 1
- Efficacy of Ecabet Sodium and Proton Pump Inhibitor Combination Therapy in the Treatment of Iatrogenic Ulcer After Endoscopic Submucosal DissectionStatus unknownNCT01308177Phase 4
- Pediatric Study for Appropriate Dose of Ritonavir Boosted Lopinavir in Thai HIV-infected Children (PEARL)CompletedNCT01307124Phase 3
- Study of the Safety and Efficacy of Intravenous Alpha-1 Antitrypsin in Type 1 Diabetes MellitusCompletedNCT01304537Phase 1/2
- Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in AdultsCompletedNCT01302093Phase 1
- Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)CompletedNCT01295632Phase 1
- Study to Evaluate the Safety and Tolerability of IV Doses of BMS-906024 in Subjects With Advanced or Metastatic Solid TumorsCompletedNCT01292655Phase 1
- Pharmacokinetic Interaction Between Maraviroc And Fosamprenavir/Ritonavir In Healthy SubjectsCompletedNCT01290211Phase 1
- TMC435-TiDP16-C108 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Digoxin and Between TMC435 and RosuvastatinCompletedNCT01288742Phase 1
- Ulinastatin in Inhalation Lung InjuryStatus unknownNCT01287806Phase 2
- Drug-Drug Interaction Study Between Telaprevir and BuprenorphineCompletedNCT01275599Phase 1
- Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected PatientsCompletedNCT01274780Phase 4
- A Study of Response-Guided Duration of Combination Therapy With GS-9451, Pegasys® and Copegus® With and Without Tegobuvir (GS-9190) in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis CCompletedNCT01271790Phase 2
- RO4929097 in Treating Patients With Recurrent Invasive GliomasTerminatedNCT01269411Phase 1
- TMC435-TiDP16-C117: The Effect of TMC435 on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy VolunteersCompletedNCT01269294Phase 1
- A Multicentre Trial of Second-line Antiretroviral Treatment Strategies in African Adults Using Atazanavir or Lopinavir/RitonavirWithdrawnNCT01255371Phase 3
- Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast CancerTerminatedNCT01254136Phase 1/2
- Drug Interaction Between Ritonavir And SitaxsentanWithdrawnNCT01251848Phase 1
- RO4929097 After Autologous Stem Cell Transplant in Treating Patients With Multiple MyelomaWithdrawnNCT01251172Phase 2
- TMC435-TiDP16-C123 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents Efavirenz and RaltegravirCompletedNCT01241773Phase 1
- Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097, Paclitaxel, and Carboplatin Before Surgery in Treating Patients With Stage II or Stage III Triple-Negative Breast CancerTerminatedNCT01238133Phase 1
- RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell LeukemiaWithdrawnNCT01236586Phase 1
- Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT)Status unknownNCT01230580Phase 4
- Antiproteinuric Effect of Imidapril Versus Ramipril in Type 2 Diabetic and Hypertensive Patients With MicroalbuminuriaStatus unknownNCT01230034Phase 3
- Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir)CompletedNCT01227590Phase 1
- A Study of Response-Guided Duration of Combination Therapy With GS-9190, GS-9256, Pegasys® and Copegus® in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis CCompletedNCT01225380Phase 2
- TMC435 HPC1004 - Phase I Study Investigating the Pharmacokinetics of TMC435 in Healthy Chinese VolunteersCompletedNCT01224197Phase 1
- HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With FosamprenavirCompletedNCT01222611Phase 4
- A Study of Danoprevir Boosted With Low Dose Ritonavir in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C Virus InfectionCompletedNCT01220947Phase 2
- Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced Solid TumorsCompletedNCT01218620Phase 1
- RO4929097 in Treating Patients With Stage IIIB, Stage IIIC, or Stage IV Melanoma That Can Be Removed by SurgeryWithdrawnNCT01216787Phase 2
- A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of WarfarinWithdrawnNCT01214122Phase 1
- GSK1349572 Drug Interaction Study With Fosamprenavir/RitonavirCompletedNCT01209065Phase 1
- RO4929097 and Letrozole in Treating Post-Menopausal Women With Hormone Receptor-Positive Stage II or Stage III Breast CancerTerminatedNCT01208441Phase 1
- TMC435-TiDP16-C114 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents TMC278 and TenofovirCompletedNCT01205139Phase 1
- TMC647055HPC1001 - First-in-human Trial to Examine Safety, Tolerability and Pharmacokinetics (How the Drug is Absorbed Into the Bloodstream) of Increasing Single Oral Doses and of Increasing Repeated Oral Doses of TMC647055 in Healthy Volunteers and in Hepatitis C Virus Infected PatientsCompletedNCT01202825Phase 1
- Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal CancerTerminatedNCT01198535Phase 1
- Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid TumorsCompletedNCT01198184Phase 1
- RO4929097 and Erlotinib Hydrochloride in Treating Patients With Stage IV or Recurrent Non-small Cell Lung CancerTerminatedNCT01193881Phase 1
- RO4929097 Before Surgery in Treating Patients With Pancreatic CancerTerminatedNCT01192763Phase 1
- PI or NNRTI as First-line Treatment of HIV in West Africa - the PIONA TrialCompletedNCT01192035Phase 4
- A Study of Danoprevir in Healthy Volunteers And Patients With Hepatic ImpairmentCompletedNCT01185873Phase 1
- A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1CompletedNCT01185860Phase 1
- A Research Trial of Aralast NP in New Onset Diabetes (RETAIN) - Part IIWithdrawnNCT01183455Phase 2
- Study of ABT-267 in Both Healthy Volunteers and Hepatitis C Virus (HCV) Genotype 1 Infected SubjectsCompletedNCT01181427Phase 1
- Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid LeukemiaStatus unknownNCT01180426Phase 2
- Effect of Neutrophil Elastase Inhibitor on Lung Injury After EsophagectomyCompletedNCT01170845Not applicable
- A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin TherapyCompletedNCT01169090Phase 2
- Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease InhibitorCompletedNCT01166477Phase 4
- Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin LymphomaWithdrawnNCT01165645Not applicable
- Nelfinavir Mesylate and Bortezomib in Treating Patients With Relapsed or Progressive Advanced Hematologic CancerCompletedNCT01164709Phase 1
- A Study of RO5190591 (Danoprevir) in Healthy VolunteersCompletedNCT01164488Phase 1
- Phase I, Exploratory, Single Centre, Single Oral Dose AZD9668 and Intravenous Microdose of [C14] AZD9668, Healthy SubjectCompletedNCT01161355Phase 1
- RO4929097 and Capecitabine in Treating Patients With Refractory Solid TumorsCompletedNCT01158274Phase 1
- Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in MexicoCompletedNCT01153854Phase 3
- RO4929097 And Exemestane in Treating Pre- and Postmenopausal Patients With Advanced or Metastatic Breast CancerTerminatedNCT01149356Phase 1
- The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy VolunteersCompletedNCT01148004Phase 1
- Single Oral Dose of 60 mg [14C]AZD9668 in Healthy Male VolunteersCompletedNCT01147549Phase 1
- Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid TumorsCompletedNCT01145456Phase 1
- Pharmacokinetic Interaction Between Maraviroc And Fosamprenavir/Ritonavir In Healthy SubjectsTerminatedNCT01140412Phase 1
- TMC114-TiDP29-C232 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir (Rtv) for Children Coming From Any of the Three Ongoing Tibotec Sponsored Pediatric Studies With DRVCompletedNCT01138605Phase 2
- Pharmacokinetics (PK) and Safety of 2 Different Doses of Lopinavir/Ritonavir in in HIV/Tuberculosis (TB) Co-infected Patients Receiving Rifampicin Containing Anti-tuberculosis TherapyCompletedNCT01138202Phase 2
- TMC435-TiDP16-C119 - A Study Comparing 2 New Capsule Formulations of TMC435 to an Established Capsule Formulation and Evaluating the Respective Blood Levels of TMC435 Following Single Dose AdministrationCompletedNCT01134718Phase 1
- Ulinastatin in Severe Acute PancreatitisSuspendedNCT01132521Phase 4