Posaconazole: all 52 studies that test it

Page 1 of 1. Open to participants first (6), then studies with results posted, then the rest; newest registration first within each.

• Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)Not yet recruitingNCT07261150Phase 3
• Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast CancerRecruitingNCT06802757Phase 2
• Study of Posaconazole Prophylaxis in Patients Receiving Hematopoietic Stem Cell Allograft (Allo-HSC) at High Risk of Invasive Fungal Infection (IFI)RecruitingNCT06541067Phase 2
• Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)RecruitingNCT04665037Phase 2
• PTX3-targeted Antifungal ProphylaxisRecruitingNCT03828773Not applicable
• Azoles Targeting Recurrent High Grade GliomasNot yet recruitingNCT03763396Early Phase 1
• Pilot Study of Posaconazole in Crohn's DiseaseTerminatedNCT04966585Phase 4Results posted
• Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical TrialTerminatedNCT04825275Early Phase 1Results posted
• Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)CompletedNCT04218851Phase 2Results posted
• Pharmacokinetics and Safety of Intravenous Posaconazole (MK-5592) in Chinese Participants at High Risk for Invasive Fungal Infections (MK-5592-120)CompletedNCT03336502Phase 1Results posted
• Posaconazole Prophylaxis During ATG Treatment for hMDS/AA PatientsCompletedNCT03318159Phase 2Results posted
• Single Dose Population Pharmacokinetics of Intravenous Posaconazole in Critically Ill PatientsCompletedNCT02968134Phase 4Results posted
• Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)CompletedNCT02452034Phase 1Results posted
• Pharmacokinetics and Safety of Oral Posaconazole (MK-5592)Tablets in Chinese Participants at High Risk for Invasive Fungal Infections (MK-5592-117)CompletedNCT02387983Phase 1Results posted
• Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)CompletedNCT02180165Phase 3Results posted
• A Study of the Effects of Posaconazole on Alectinib (RO5424802) Pharmacokinetics in Healthy VolunteersCompletedNCT01984229Phase 1Results posted
• A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)CompletedNCT01782131Phase 3Results posted
• Pharmacokinetics and Safety of Posaconazole Tablet in Participants at High Risk for Invasive Fungal Infections (MK-5592-065/P05615)CompletedNCT01777763Phase 1Results posted
• A Study of the Safety, Tolerance, and Pharmacokinetics of Oral Posaconazole in Immunocompromised Children (P03579)TerminatedNCT01716234Phase 1Results posted
• A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105)TerminatedNCT01667107Phase 4Results posted
• A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267)CompletedNCT01377480Phase 2Results posted
• Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic SyndromeCompletedNCT01200355Phase 4Results posted
• Pharmacokinetics of Posaconazole Prophylaxis in Acute LeukemiaCompletedNCT00936117Phase 2Results posted
• Safety and Efficacy Study of Posaconazole vs. Fluconazole for Prevention of Invasive Fungal Infection (P05387 AM1)(COMPLETED)CompletedNCT00811928Phase 3Results posted
• Posaconazole Treatment of Invasive Fungal Infection (IFI) (P05551)CompletedNCT00811642Phase 3Results posted
• Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)CompletedNCT00750737Phase 3Results posted
• Oral Posaconazole in High Risk Patients With Gastrointestinal Dysfunction (Study P05115)CompletedNCT00686543Phase 4Results posted
• A Study to Examine the Efficacy and Safety of Posaconazole When Introduced Early in the Treatment of Refractory Fungal Infections (P05090 AM2)CompletedNCT00550732Phase 2Results posted
• A Study to Evaluate Efficacy and Safety of Four Posaconazole Regimens With Placebo and Terbinafine in the Treatment of Toenail Onychomycosis (Study P05082AM2)(COMPLETED)CompletedNCT00491764Phase 2Results posted
• POS vs FLU for First Line Treatment of Coccidioidomycosis (Study P04558Am1)(COMPLETED)CompletedNCT00423267Phase 3Results posted
• Amphotericin Versus Posaconazole for Pulmonary MucormycosisCompletedNCT05468372Phase 2
• A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus InfectionStatus unknownNCT04966234Phase 2/3
• Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of HepatotoxicityStatus unknownNCT03796533Not applicable
• Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy ParticipantsCompletedNCT03614455Early Phase 1
• Dosing Obese With Noxafil® Under a Trial (DONUT)CompletedNCT03246386Phase 4
• Drug/Drug Interactions With F901318WithdrawnNCT03095547Phase 1
• Safety and Pharmacokinetics of Oral F901318 (Fluconazole and Posaconazole) IN Aml LeukaemiaWithdrawnNCT03036046Phase 1/2
• King's Invasive Aspergillosis Study IICompletedNCT02875743Phase 4
• Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal InfectionsCompletedNCT02805946Phase 4
• Genetic Variation and Variability in Posaconazole Pharmacokinetics in ChildrenCompletedNCT02358499Phase 1
• Posaconazole as Salvage Therapy for Aspergillus Pulmonary Infection.WithdrawnNCT02020213Phase 4
• A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid TumorsCompletedNCT01901172Phase 1
• Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And BenznidazoleCompletedNCT01162967Phase 2
• Pharmacokinetic Study of Posaconazole Boosted FosamprenavirCompletedNCT00817765Phase 1
• Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD)CompletedNCT00799071Phase 2
• Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095TerminatedNCT00177749Phase 4
• Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899)CompletedNCT00044486Phase 3
• PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)CompletedNCT00034671Phase 2
• Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041)CompletedNCT00034658Phase 3
• Prophylaxis Trial in High Risk Allogenic Stem Cell Transplant Recipients With Graft vs. Host DiseaseCompletedNCT00034645Phase 3
• Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095)CompletedNCT00034632Phase 3
• Posaconazole to Treat Invasive Fungal InfectionsCompletedNCT00033982Phase 3

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