Histoplasmosis clinical trials
The registry lists 27 studies for Histoplasmosis across more than 10 countries. 5 are recruiting or about to start. 9 of them are mainly about Histoplasmosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (5) · University of Minnesota (2) · Janssen, LP (2) · National Center for Research Resources (NCRR) (2) · National Eye Institute (NEI) (2) · University of Alabama at Birmingham (1) · Scynexis, Inc. (1) · Alessandro Pasqualotto (1)
What is being tested here
Drugs under test in Histoplasmosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Posaconazole | 1 | 1 | 1 |
| VT-1161 | 1 | 0 | 1 |
| Itraconazole | 0 | 1 | 6 |
| Fluconazole | 0 | 0 | 2 |
| Ranibizumab | 0 | 0 | 2 |
| Ibrexafungerp | 0 | 1 | 1 |
| Itraconazole Dispersion In Polymer Matrix | 0 | 1 | 1 |
| Amphotericin B | 0 | 1 | 1 |
| Aflibercept | 0 | 0 | 1 |
Drug classes tested here Angiogenesis inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
Who these studies take
Of the 2 Histoplasmosis studies recruiting now, 2 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (100%) | 2 (100%) |
| 30 | 2 (100%) | 2 (100%) |
| 40 | 2 (100%) | 2 (100%) |
| 50 | 2 (100%) | 2 (100%) |
| 65 | 2 (100%) | 2 (100%) |
| 75 | 2 (100%) | 2 (100%) |
| 85 | 2 (100%) | 2 (100%) |
Across all 27 studies, recruiting or not: 4% stop at 75 or younger and 4% at 65; 33% take children; 0% are for women only and 4% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 27 of 27. search them.
- Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)Not yet recruitingNCT07261150Phase 32 countries
- Assessment of the Risk of Zoonotic Infections in Prisons in French GuianaNot yet recruitingNCT078087751 country
- Platform Trial for Salvage Consolidation Therapy in Dimorphic FungiNot yet recruitingNCT07804368Phase 21 country
- Efficacy and Safety of High-dose Liposomal Amphotericin B for Disseminated Histoplasmosis in AIDSRecruitingNCT05814432Phase 31 country
- A Prospective Longitudinal Analysis of Faricimab (Vabysmo 6mg) For Choroidal Neovascularization in Presumed Ocular Histoplasmosis SyndromeRecruitingNCT07695298Phase 41 country
- Randomized Trial of Liposomal Amphotericin B for Histoplasmosis in AIDS PatientsCompletedNCT04059770Phase 21 country
- Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal TreatmentCompletedNCT03059992Phase 38 countries
- Prevalence of Histoplasmosis in HIV + Patients with a Rapid Diagnostic Test in West IndiesCompletedNCT018847792 countries
- Endemic Mycoses Treatment With SUBA-itraconazole vs ItraconazoleCompletedNCT03572049Phase 2/32 countries
- A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000975Phase 21 country
- Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasmosis in Patients With the Acquired Immunodeficiency SyndromeCompletedNCT00000627Not applicable1 country
- A Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000992Phase 11 country
- Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, PanamaWithdrawnNCT02911740Not applicable
- A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male VolunteersCompletedNCT02493738Phase 11 country
- Treatment for Presumed Ocular HistoplasmosisStatus unknownNCT01790893Phase 1/21 country
- A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal InfectionCompletedNCT00784368Phase 31 country
- Submacular Surgery Trials (SST)CompletedNCT00000150Phase 3
- Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Ocular Histoplasmosis SyndromeStatus unknownNCT00955630Phase 1/21 country
- Ranibizumab Versus PDT for Presumed Ocular HistoplasmosisStatus unknownNCT00546936Phase 21 country
- A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) InfectionCompletedNCT000055721 country
- Withdrawal of Antifungal Treatment for Histoplasmosis in Patients After Improved Immune Response to Anti-HIV DrugsCompletedNCT000063161 country
- Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular NeovascularizationCompletedNCT006456971 country
- Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and SporotrichosisCompletedNCT00004808Phase 2
- Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and SporotrichosisCompletedNCT00004811Phase 1/2
- A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected PatientsCompletedNCT00002438Not applicable1 country
- A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or HistoplasmosisCompletedNCT00002159Phase 31 country
- Macular Photocoagulation Study (MPS)Status unknownNCT00000158Phase 3