An interventional study of Cardiac SPECT imaging Rest and Stress and Caffeine in Coronary Artery Disease, sponsored by University of Wisconsin, Madison. Completed at 1 site in United States. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2012-10-29.
Sponsored by University of Wisconsin, Madison · Not applicable, Interventional, and Diagnostic
We are studying the affect of caffeine on the sensitivity of detecting coronary artery disease (blockages in the blood flow to the heart) with adenosine tracer scans. Adenosine is a drug used routinely in patients to relax heart blood vessels in order to assess for the presence of coronary artery disease. Often, if patients have had caffeine, the adenosine scan is not used because of the belief that caffeine may reduce the ability to detect coronary artery disease. We would like to test whether caffeine affects our ability to detect coronary artery disease with adenosine tracer scanning. We will perform an imaging study of the heart with adenosine after you have received caffeine.
5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.
This study's enrollment of 50 is below the median of 124 across 3,436 interventional studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →University of Wisconsin, Madison is the lead sponsor of 1,161 studies on the registry; 182 are open to participants now.
Of its 151 completed or terminated interventional studies of FDA-regulated products, 114 (75%) have results posted.
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Exclusion Criteria:
Caffeine 400 mg PO 1 hour before adenosine infusion
Procedure: Cardiac SPECT imaging Rest and Stress · Drug: Caffeine
Caffeine 200 mg po one hour before adenosine infusion
Procedure: Cardiac SPECT imaging Rest and Stress · Drug: Caffeine
adenosine perfusion scintigraphy
Caffeine 400 mg po
Caffeine 200 mg po
This protocol has a specific aim of determining whether prior caffeine administration affects the sensitivity and specificity of adenosine perfusion scintigraphy for detection of impaired coronary vascular reserve.
Time frame: Assessment is made at the time of research adenosine perfusion scintigraphy
determination of caffeine levels in patients instructed to hold caffeine prior to adenosine imaging
Time frame: Assess at time of lab sample results obtained
This study is completed, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.
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University of Wisconsin, Madison