Pembrolizumab: given beside what is tested

1,547 studies: usual care or a partner of the new treatment. Page 8 of 16. Open to participants first (520), then studies with results posted, then the rest; newest registration first within each.

First-time-in-human (FTIH) Study of GSK3145095 Alone and in Combination With Other Anticancer Agents in Adults With Advanced Solid TumorsTerminatedNCT03681951Phase 2Results posted Report a problem
Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With PembrolizumabCompletedNCT03674567Phase 1/2Results posted Report a problem
Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal CancerActive, not recruitingNCT03657641Phase 1/2Results posted Report a problem
Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant MesotheliomaCompletedNCT03654833Phase 2Results posted Report a problem
Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaCompletedNCT03650764Phase 1/2Results posted Report a problem
Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant MesotheliomaTerminatedNCT03644550Phase 2Results posted Report a problem
A Study to Evaluate Concurrent VRP-HER2 Vaccination and Pembrolizumab for Patients With Breast CancerTerminatedNCT03632941Phase 2Results posted Report a problem
Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)CompletedNCT03631407Phase 2Results posted Report a problem
Study of Efficacy and Safety of Pembrolizumab Plus Platinum-based Doublet Chemotherapy With or Without Canakinumab in Previously Untreated Locally Advanced or Metastatic Non-squamous and Squamous NSCLC SubjectsTerminatedNCT03631199Phase 3Results posted Report a problem
Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCCCompletedNCT03625323Phase 2Results posted Report a problem
Study of ADCT-301 in Patients With Selected Advanced Solid TumorsTerminatedNCT03621982Phase 1Results posted Report a problem
Denosumab + PD-1 in Subjects With Stage III/ IV MelanomaCompletedNCT03620019Phase 2Results posted Report a problem
A Phase 2 Study of Sitravatinib in Combination With PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial CarcinomaTerminatedNCT03606174Phase 2Results posted Report a problem
Testing Whether the Combination of Two Immunotherapy Drugs Have Activity in Recurrent or Persistent Clear Cell Ovarian CancerCompletedNCT03602586Phase 2Results posted Report a problem
Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell LymphomasActive, not recruitingNCT03598998Phase 1/2Results posted Report a problem
Pembrolizumab and EDP1503 in Advanced MelanomaTerminatedNCT03595683Phase 2Results posted Report a problem
Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced CancersCompletedNCT03568058Phase 1Results posted Report a problem
A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular CarcinomaCompletedNCT03519997Phase 2Results posted Report a problem
A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495)CompletedNCT03516981Phase 2Results posted Report a problem
FPA150 in Patients With Advanced Solid TumorsTerminatedNCT03514121Early Phase 1Results posted Report a problem
UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint BlockadeActive, not recruitingNCT03474497Phase 1/2Results posted Report a problem
Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034)CompletedNCT03473925Phase 2Results posted Report a problem
Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior ImmunotherapyTerminatedNCT03463161Phase 2Results posted Report a problem
Study of a Combination of GSK1795091 and Immunotherapies in Subjects With Advanced Solid TumorsCompletedNCT03447314Phase 1Results posted Report a problem
The Combination of GX-188E Vaccination and Pembrolizumab in Patients With HPV 16 and/or 18+ Advanced Cervical CancerCompletedNCT03444376Phase 1/2Results posted Report a problem
PembRolIzuMab and Stereotactic Body Radiotherapy In Metastatic Non-small-cell lunG Cancer PatientsTerminatedNCT03436056Phase 1Results posted Report a problem
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed GlioblastomaCompletedNCT03426891Phase 1Results posted Report a problem
Pembrolizumab and Itacitinib (INCB039110) for Non-Small Cell Lung CancerTerminatedNCT03425006Phase 2Results posted Report a problem
A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic ProfileTerminatedNCT03416335Phase 1/2Results posted Report a problem
A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced SarcomaActive, not recruitingNCT03414229Phase 2Results posted Report a problem
Immunologic Determinants of Response to Pembrolizumab (MK-3475) in Advanced Melanoma (MK-3475-161/KEYNOTE-161)TerminatedNCT03407170Phase 2Results posted Report a problem
Pembro and HER2Bi-Armed Activated T Cells in Treating Patients With Metastatic Castration Resistant Prostate CancerCompletedNCT03406858Phase 2Results posted Report a problem
Prostaglandin Inhibition and Immune Checkpoint Blockade in MelanomaCompletedNCT03396952Phase 2Results posted Report a problem
Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal CancerCompletedNCT03396926Phase 2Results posted Report a problem
Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001)CompletedNCT03396445Phase 1Results posted Report a problem
Radiotherapy With Pembrolizumab in Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)TerminatedNCT03386357Phase 2Results posted Report a problem
Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung CancerTerminatedNCT03382899Phase 2Results posted Report a problem
Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial CarcinomaCompletedNCT03374488Phase 3Results posted Report a problem
Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung CancerTerminatedNCT03371979Phase 1/2Results posted Report a problem
Study of MK-7162 in Combination With Pembrolizumab (MK-3475) in Adult Participants With Advanced Solid Tumors (MK-7162-002)CompletedNCT03364049Phase 1Results posted Report a problem
Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)CompletedNCT03361865Phase 3Results posted Report a problem
A Study to Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid TumorsTerminatedNCT03361228Phase 1/2Results posted Report a problem
DPX-Survivac and Checkpoint Inhibitor in DLBCLCompletedNCT03349450Phase 2Results posted Report a problem
Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With GlioblastomaTerminatedNCT03347617Phase 2Results posted Report a problem
Fecal Microbiota Transplant (FMT) in Melanoma PatientsCompletedNCT03341143Phase 2Results posted Report a problem
Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)CompletedNCT03340766Phase 1Results posted Report a problem
Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal CancersCompletedNCT03332498Phase 1/2Results posted Report a problem
A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic CancerCompletedNCT03331562Phase 2Results posted Report a problem
Pembrolizumab and Magnetic Resonance Imaging With Ferumoxytol in Treating Patients With Non-small Cell Lung Cancer and Brain MetastasesTerminatedNCT03325166Phase 2Results posted Report a problem
Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable MelanomaTerminatedNCT03325101Phase 1/2Results posted Report a problem
A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)CompletedNCT03322566Phase 2Results posted Report a problem
Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)CompletedNCT03322540Phase 2Results posted Report a problem
Priming Immunotherapy in Advanced Disease With RadiationCompletedNCT03313804Phase 2Results posted Report a problem
A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid TumorsTerminatedNCT03311334Phase 1/2Results posted Report a problem
Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast CancerCompletedNCT03310957Phase 1/2Results posted Report a problem
Mogamulizumab and Pembrolizumab in Treating Patients With Relapsed or Refractory Diffuse Large B Cell LymphomaCompletedNCT03309878Phase 1/2Results posted Report a problem
Effects of Single Agent Niraparib and Niraparib Plus Programmed Cell Death-1 (PD-1) Inhibitors in Non-Small Cell Lung Cancer ParticipantsCompletedNCT03308942Phase 2Results posted Report a problem
Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell CarcinomaCompletedNCT03304639Phase 2Results posted Report a problem
Study of Pembrolizumab Given With Ipilimumab or Placebo in Participants With Untreated Metastatic Non-Small Cell Lung Cancer (NSCLC) (MK-3475-598/KEYNOTE-598)CompletedNCT03302234Phase 3Results posted Report a problem
A Study of Indoximod or Placebo Plus Pembrolizumab or Nivolumab for Subjects With Unresectable or Metastatic MelanomaTerminatedNCT03301636Phase 2Results posted Report a problem
Epacadostat and Pembrolizumab in Patients With GISTTerminatedNCT03291054Phase 2Results posted Report a problem
Cluster of Differentiation Antigen 19/22(CD19/22) CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell LymphomaTerminatedNCT03287817Phase 1/2Results posted Report a problem
INCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic MalignanciesTerminatedNCT03277352Phase 1/2Results posted Report a problem
Her2-BATS and Pembrolizumab in Metastatic Breast CancerActive, not recruitingNCT03272334Phase 1/2Results posted Report a problem
Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)CompletedNCT03260894Phase 3Results posted Report a problem
Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney CancerTerminatedNCT03260504Phase 1Results posted Report a problem
Pembrolizumab + Idelalisib for Lung Cancer StudyTerminatedNCT03257722Phase 1/2Results posted Report a problem
Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001)TerminatedNCT03249792Phase 1Results posted Report a problem
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)TerminatedNCT03241927Phase 2Results posted Report a problem
Pembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid TumorCompletedNCT03239145Phase 1Results posted Report a problem
Phase Ib of L-NMMA and PembrolizumabCompletedNCT03236935Phase 1Results posted Report a problem
Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal CarcinomasTerminatedNCT03233724Phase 1/2Results posted Report a problem
Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or LymphomaCompletedNCT03229278Phase 1Results posted Report a problem
Pembrolizumab With and Without Radiotherapy for Non-Small Cell Lung CancerCompletedNCT03217071Phase 2Results posted Report a problem
Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric CancerCompletedNCT03196232Phase 2Results posted Report a problem
Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)CompletedNCT03184571Phase 2Results posted Report a problem
Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With TNBCTerminatedNCT03184558Phase 2Results posted Report a problem
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)CompletedNCT03179436Phase 1/2Results posted Report a problem
Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)TerminatedNCT03175172Phase 2Results posted Report a problem
Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple MyelomaTerminatedNCT03168438Phase 1Results posted Report a problem
Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the PancreasCompletedNCT03153410Early Phase 1Results posted Report a problem
Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.Active, not recruitingNCT03150329Phase 1Results posted Report a problem
Study of Pembrolizumab and Cabozantinib in Patients With Metastatic Renal Cell CarcinomaCompletedNCT03149822Phase 1/2Results posted Report a problem
Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid TumorsTerminatedNCT03138889Phase 1/2Results posted Report a problem
Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerActive, not recruitingNCT03137771Phase 2Results posted Report a problem
Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural MesotheliomaActive, not recruitingNCT03126630Phase 1/2Results posted Report a problem
A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue SarcomaCompletedNCT03126591Phase 1Results posted Report a problem
Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic SarcomaCompletedNCT03123276Phase 1/2Results posted Report a problem
A Study of B-701 in Combination With Pembrolizumab in Treatment of Locally Advanced or Metastatic Urothelial Cell CarcinomaTerminatedNCT03123055Phase 1/2Results posted Report a problem
Safety and Efficacy of CRS-207 With Pembrolizumab in Gastric, Gastroesophageal Junction or Esophageal CancersTerminatedNCT03122548Phase 2Results posted Report a problem
A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary CancersTerminatedNCT03115801Phase 2Results posted Report a problem
P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerActive, not recruitingNCT03113487Phase 2Results posted Report a problem
Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical CarcinomaTerminatedNCT03108495Phase 2Results posted Report a problem
Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast CancerCompletedNCT03106415Phase 1/2Results posted Report a problem
Study of Preladenant (MK-3814) Alone and With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3814A-062)TerminatedNCT03099161Phase 1Results posted Report a problem
Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal CancerCompletedNCT03095781Phase 1Results posted Report a problem
Dendritic Cell Vaccination in Patients With Advanced MelanomaCompletedNCT03092453Phase 1Results posted Report a problem
Pembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging BiomarkerCompletedNCT03089606Phase 2Results posted Report a problem
A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)CompletedNCT03085914Phase 1/2Results posted Report a problem
Targeting PD-1 Therapy Resistance With Focused High or High and Low Dose Radiation in SCCHNActive, not recruitingNCT03085719Phase 2Results posted Report a problem

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