Pembrolizumab: given beside what is tested

1,547 studies: usual care or a partner of the new treatment. Page 9 of 16. Open to participants first (520), then studies with results posted, then the rest; newest registration first within each.

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6CompletedNCT03058289Phase 1/2Results posted Report a problem
Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney CancerTerminatedNCT03050060Phase 2Results posted Report a problem
Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475CompletedNCT03049618Phase 2Results posted Report a problem
Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung CancerCompletedNCT03035890Not applicableResults posted Report a problem
Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin LymphomaCompletedNCT03035331Phase 1/2Results posted Report a problem
Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)TerminatedNCT03018288Phase 2Results posted Report a problem
Study of Ulevostinag (MK-1454) Alone or in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors or Lymphomas (MK-1454-001)CompletedNCT03010176Phase 1Results posted Report a problem
Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable CancerTerminatedNCT03009058Phase 1/2Results posted Report a problem
Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADTCompletedNCT03007732Phase 2Results posted Report a problem
Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas CancerCompletedNCT03006302Phase 2Results posted Report a problem
SBRT and Oncolytic Virus Therapy Before Pembrolizumab for Metastatic TNBC and NSCLCCompletedNCT03004183Phase 2Results posted Report a problem
A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death Protein 1 (PD1) BlockadeCompletedNCT03003676Phase 1Results posted Report a problem
Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017CompletedNCT03003468Phase 1/2Results posted Report a problem
Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal CancerCompletedNCT02981524Phase 2Results posted Report a problem
Study of Imprime PGG and Pembrolizumab in Advanced Melanoma and Triple Negative Breast CancerCompletedNCT02981303Phase 2Results posted Report a problem
Study of MK-8353 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Malignancies (MK-8353-013)TerminatedNCT02972034Phase 1Results posted Report a problem
Pembrolizumab and Enobosarm in Treating Patients With Androgen Receptor Positive Metastatic Triple Negative Breast CancerCompletedNCT02971761Phase 2Results posted Report a problem
Study of Vibostolimab Alone and in Combination With Pembrolizumab in Advanced Solid Tumors (MK-7684-001) ( KEYVIBE-001)CompletedNCT02964013Phase 1Results posted Report a problem
Phase I/II Study of Lenalidomide Plus Pembrolizumab in Patients With Solid Tumors With Expansion in Non-small Cell Lung CancerTerminatedNCT02963610Phase 1/2Results posted Report a problem
Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)TerminatedNCT02959437Phase 1/2Results posted Report a problem
Pembrolizumab in Patients With Metastatic Non-squamous Non-small Cell Lung CancerCompletedNCT02955758Phase 2Results posted Report a problem
Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic MutationsTerminatedNCT02949843Phase 2Results posted Report a problem
Testing the Safety and Efficacy of the Combination of the Antibody Pembrolizumab and Entinostat in Patients With Myelodysplastic Syndrome Who Are Not Responding to Hypomethylating AgentsCompletedNCT02936752Phase 1Results posted Report a problem
Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal CancerTerminatedNCT02933944Phase 1Results posted Report a problem
Pembrolizumab and CXCR4 Antagonist BL-8040 in Treating Patients With Metastatic Pancreatic CancerCompletedNCT02907099Phase 2Results posted Report a problem
JTX-2011 Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid TumorsCompletedNCT02904226Phase 1/2Results posted Report a problem
Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid TumorsCompletedNCT02903914Phase 1Results posted Report a problem
Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT02901899Phase 2Results posted Report a problem
Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian CancerTerminatedNCT02900560Phase 2Results posted Report a problem
Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by SurgeryCompletedNCT02888665Phase 1/2Results posted Report a problem
A Study of ARRY-382 in Combination With Pembrolizumab for the Treatment of Patients With Advanced Solid TumorsTerminatedNCT02880371Phase 1/2Results posted Report a problem
Safety & Efficacy Study of Combination of Pembrolizumab and Lenalidomide, in Patients With Relapsed Non-Hodgkin and Hodgkin LymphomaTerminatedNCT02875067Phase 1/2Results posted Report a problem
Study of Epacadostat (INCB024360) Alone and In Combination With Pembrolizumab (MK-3475) With Chemotherapy and Pembrolizumab Without Chemotherapy in Participants With Advanced Solid Tumors (MK-3475-434)CompletedNCT02862457Phase 1Results posted Report a problem
Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain MetastasesCompletedNCT02858869Phase 1Results posted Report a problem
Pembrolizumab + Poly-ICLC in MRP Colon CancerCompletedNCT02834052Phase 1/2Results posted Report a problem
Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer PatientsCompletedNCT02826486Phase 2Results posted Report a problem
A Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid TumorsCompletedNCT02799095Phase 1/2Results posted Report a problem
An Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK3326595 in Participants With Solid Tumors and Non-Hodgkin's LymphomaCompletedNCT02783300Phase 1Results posted Report a problem
A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)CompletedNCT02752074Phase 3Results posted Report a problem
Aldesleukin and Pembrolizumab in Treating Patients With Stage III-IV MelanomaTerminatedNCT02748564Phase 2Results posted Report a problem
Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive BiomarkerTerminatedNCT02740920Phase 2Results posted Report a problem
Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)CompletedNCT02723955Phase 1Results posted Report a problem
Study of Favezelimab (MK-4280) as Monotherapy and in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy or Lenvatinib (MK-7902) AND Favezelimab/Pembrolizumab (MK-4280A) as Monotherapy in Adults With Advanced Solid Tumors (MK-4280-001)CompletedNCT02720068Phase 1Results posted Report a problem
Safety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor CancerCompletedNCT02713529Phase 1/2Results posted Report a problem
APX005M in Combination With Systemic Pembrolizumab in Patients With Metastatic MelanomaTerminatedNCT02706353Phase 1/2Results posted Report a problem
Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction CancerCompletedNCT02689284Phase 1/2Results posted Report a problem
Study of Pembrolizumab (MK-3475) in Combination With Dinaciclib (MK-7965) in Hematologic Malignancies (MK-3475-155/KEYNOTE-155)TerminatedNCT02684617Phase 1Results posted Report a problem
Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian CancerCompletedNCT02657889Phase 1/2Results posted Report a problem
Study With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic CancerCompletedNCT02648282Phase 2Results posted Report a problem
A Phase 2 Study to Assess the Safety and Efficacy of IMO-2125 With 8 mg Ipilimumab in Patients With Metastatic MelanomaCompletedNCT02644967Phase 2Results posted Report a problem
Pembro and Vorinostat for Patients With Stage IV Non-small Cell Lung Cancer (NSCLC)Active, not recruitingNCT02638090Phase 1/2Results posted Report a problem
Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell CarcinomaCompletedNCT02619253Phase 1Results posted Report a problem
Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT02606305Phase 1/2Results posted Report a problem
Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary TumorsCompletedNCT02599324Phase 1/2Results posted Report a problem
Dose-escalation Study of Birinapant and Pembrolizumab in Solid TumorsTerminatedNCT02587962Phase 1/2Results posted Report a problem
Pembrolizumab and Palliative Radiotherapy in LungCompletedNCT02587455Phase 1Results posted Report a problem
Effect of Pembrolizumab With or Without Carboplatin and Paclitaxel on Immune Response in Patients With Recurrent or Stage IIIB-IV Non-small Cell Lung CancerCompletedNCT02581943Phase 2Results posted Report a problem
Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian or Peritoneal CancerTerminatedNCT02575807Phase 1/2Results posted Report a problem
A Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) With Pembrolizumab in Participants With Selected Hyaluronan High Solid TumorsCompletedNCT02563548Phase 1Results posted Report a problem
Trial of Pembrolizumab and Radiotherapy in MelanomaTerminatedNCT02562625Phase 2Results posted Report a problem
Study of MK-1248 With and Without Pembrolizumab (MK-3475) for Participants With Advanced Solid Tumors (MK-1248-001)TerminatedNCT02553499Phase 1Results posted Report a problem
Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung CancerTerminatedNCT02546986Phase 2Results posted Report a problem
Acalabrutinib (ACP-196) Alone and in Combination With Pembrolizumab in Ovarian Cancer (KEYNOTE191)CompletedNCT02537444Phase 2Results posted Report a problem
GSK3174998 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors (ENGAGE-1)CompletedNCT02528357Phase 1Results posted Report a problem
A Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT02521870Phase 1/2Results posted Report a problem
Safety Study of a Helper Peptide Vaccine Plus PembrolizumabCompletedNCT02515227Phase 1/2Results posted Report a problem
Crizotinib Plus Pembrolizumab In Alk-Positive Advanced Non Small Cell Lung Cancer PatientsTerminatedNCT02511184Phase 1Results posted Report a problem
Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611CompletedNCT02509507Phase 1/2Results posted Report a problem
Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Participants With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142)TerminatedNCT02501473Phase 1/2Results posted Report a problem
A Trial of Lenvatinib (E7080) Plus Pembrolizumab in Participants With Selected Solid TumorsCompletedNCT02501096Phase 1/2Results posted Report a problem
Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant, Metastatic Prostate CancerCompletedNCT02499835Phase 1/2Results posted Report a problem
Trial of pIL-12/MK-3475 in Metastatic MelanomaCompletedNCT02493361Phase 2Results posted Report a problem
Safety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerCompletedNCT02475213Phase 1Results posted Report a problem
Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell CarcinomaCompletedNCT02454179Phase 2Results posted Report a problem
A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid TumorsTerminatedNCT02452424Phase 1/2Results posted Report a problem
A Study of the Combination of Necitumumab (LY3012211) and Pembrolizumab (MK3475) in Participants With NSCLCCompletedNCT02451930Phase 1Results posted Report a problem
Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung CancerCompletedNCT02448303Phase 2Results posted Report a problem
A Study of Combination Therapies With Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung CancerCompletedNCT02439450Phase 1/2Results posted Report a problem
Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)CompletedNCT02437136Phase 1/2Results posted Report a problem
Evaluating the Combination of MK-3475 and Sterotactic Body Radiotherapy in Patients With Metastatic Melanoma or NSCLCCompletedNCT02407171Phase 1/2Results posted Report a problem
Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101)TerminatedNCT02393248Phase 1/2Results posted Report a problem
Pembrolizumab and Epacadostat in Patients With Thymic CarcinomaStatus unknownNCT02364076Phase 2Results posted Report a problem
ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic CancerCompletedNCT02362048Phase 2Results posted Report a problem
ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic MalignanciesCompletedNCT02362035Phase 1/2Results posted Report a problem
Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder CancerCompletedNCT02351739Phase 2Results posted Report a problem
Phase Ib and Phase II Studies of MK-3475 in Combination + for Renal Cell Carcinoma:CompletedNCT02348008Phase 1/2Results posted Report a problem
ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)CompletedNCT02325557Phase 1/2Results posted Report a problem
A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced MelanomaTerminatedNCT02302339Phase 2Results posted Report a problem
Pembrolizumab With Talimogene Laherparepvec or Placebo in Unresected MelanomaTerminatedNCT02263508Phase 3Results posted Report a problem
A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B1641003/KEYNOTE-0036)CompletedNCT02179918Phase 1Results posted Report a problem
Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected CancersCompletedNCT02178722Phase 1/2Results posted Report a problem
Study of MK-4166 and MK-4166 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4166-001)CompletedNCT02132754Phase 1Results posted Report a problem
A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC)CompletedNCT02079636Phase 1Results posted Report a problem
Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic MelanomaCompletedNCT02073123Phase 1/2Results posted Report a problem
Immunotherapy Study for Patients With Stage IV MelanomaTerminatedNCT02054520Phase 2Results posted Report a problem
A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsCompletedNCT02009449Phase 1Results posted Report a problem
Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic NSCLCSuspendedNCT07639242Phase 2 Report a problem
Phase 3 Study of Nogapendekin Alfa Inbakicept Plus Standard of Care vs Standard of Care in First-Line Advanced or Metastatic NSCLCWithdrawnNCT07524257Phase 3 Report a problem
Study of NGM707 in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesWithdrawnNCT07511972Phase 2 Report a problem
IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic MelanomaCompletedNCT07436390Not applicable Report a problem

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