Biological
Pembrolizumab/Quavonlimab MK-1308A clinical trials
Also written MK-1308A.
- studies test it
- 10
- open now
- 0
- in phase 3
- 2
- first study started
- 2017
How studies write it
Studies that test it under each name
Development codes
- MK-1308A
- 10
Studies by the year they started
10 studies that test it; most in 2021 (5)
| Year | Studies |
|---|---|
| 2017 | 1 |
| 2020 | 3 |
| 2021 | 5 |
| 2022 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 6
- Phase 2
- 8
- Phase 3
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 0
Often tested with
Tested in the same studies.
Pembrolizumab (8) · Belzutifan (4) · Favezelimab (4) · Lenvatinib (4) · Vibostolimab (2) · Anti-ILT4 Monoclonal Antibody MK-4830 (1) · Favezelimab/Pembrolizumab Formulation (1) · Raludotatug deruxtecan (1)
Studies
Open first, then newest update. How each study uses Pembrolizumab/Quavonlimab MK-1308A is read from its arms, and is right about nine times in ten.
Testing it · 10
- A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)Active, not recruitingPhase 3Merck Sharp & Dohme LLCNCT04736706Written as Pembrolizumab/Quavonlimab
- Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04626518Written as Pembrolizumab/Quavonlimab
- Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04626479Written as Pembrolizumab/Quavonlimab
- A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension StudyActive, not recruitingPhase 3Merck Sharp & Dohme LLCNCT05899049Written as Pembrolizumab/Quavonlimab
- Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).Active, not recruitingPhase 2Merck Sharp & Dohme LLCNCT04895722Written as Pembrolizumab/Quavonlimab
- Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)CompletedPhase 2Merck Sharp & Dohme LLCNCT04740307Written as Pembrolizumab/Quavonlimab
- Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)Active, not recruitingPhase 1/2Merck Sharp & Dohme LLCNCT04938817Written as coformulation pembrolizumab/quavonlimab
- Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04305054Written as Pembrolizumab/Quavonlimab
- Substudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04700072Written as Pembrolizumab/Quavonlimab
- Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT03179436Written as Pembrolizumab/Quavonlimab