BiologicalDrug
Anti-ILT4 Monoclonal Antibody MK-4830 clinical trials
Also written MK-4830.
- studies test it
- 4
- open now
- 0
- in phase 3
- 0
- first study started
- 2018
How studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
4 studies that test it; most in 2022 (2)
| Year | Studies |
|---|---|
| 2018 | 1 |
| 2021 | 1 |
| 2022 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 2
- Phase 2
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 0
Merck Sharp & Dohme LLC (3) · Presage Biosciences (1)
Often tested with
Tested in the same studies.
Pembrolizumab (2) · Pembrolizumab/Quavonlimab MK-1308A (1) · Lenvatinib (1) · Favezelimab/Pembrolizumab Formulation (1) · Raludotatug deruxtecan (1) · MK-4830A (1) · Rolistobart (1)
Studies
Open first, then newest update. How each study uses Anti-ILT4 Monoclonal Antibody MK-4830 is read from its arms, and is right about nine times in ten.
Testing it · 4
- Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)Active, not recruitingPhase 1/2Merck Sharp & Dohme LLCNCT04938817Written as MK-4830
- Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)CompletedPhase 1Merck Sharp & Dohme LLCNCT03564691Written as MK-4830
- Pembrolizumab With Chemotherapy and MK-4830 for Treating Participants With Ovarian Cancer (MK-4830-002)CompletedPhase 2Merck Sharp & Dohme LLCNCT05446870Written as MK-4830
- PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STSCompletedEarly Phase 1Presage BiosciencesNCT06413095Written as MK-4830 + Pembrolizumab
Given in every arm · 9 — Anti-ILT4 Monoclonal Antibody MK-4830 is usual care beside what is tested
- A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT05319730Written as MK-4830
- KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)RecruitingPhase 1/2Merck Sharp & Dohme LLCNCT04165070Written as MK-4830
- Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04626518Written as MK-4830
- Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT04303169Written as MK-4830
- Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99)CompletedPhase 2Merck Sharp & Dohme LLCNCT04924101Written as MK-4830
- Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).Active, not recruitingPhase 2Merck Sharp & Dohme LLCNCT04895722Written as MK-4830
- KEYMAKER-U01 Substudy 3: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Participants With Advanced Non-small Cell Lung Cancer (NSCLC), Previously Treated With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Therapy (MK-3475-01C/KEYMAKER-U01C)CompletedPhase 2Merck Sharp & Dohme LLCNCT04165096Written as MK-4830
- A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A)CompletedPhase 1/2Merck Sharp & Dohme LLCNCT05342636Written as MK-4830
- KEYMAKER-U01 Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-01B/KEYMAKER-U01B)CompletedPhase 2Merck Sharp & Dohme LLCNCT04165083Written as MK-4830