Drug
Nomegestrol acetate clinical trials
Also written Zoely.
A product of Megestrol; its studies count on that page too.
- studies test it
- 17
- open now
- 0
- in phase 3
- 8
- first study started
- 1997
How studies write it
Studies that test it under each name
Brand
Other names
Combined with it in one product
Studies by the year they started
17 studies that test it; most in 2006 (5)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 2006 | 5 |
| 2007 | 1 |
| 2009 | 1 |
| 2012 | 3 |
| 2013 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2022 | 1 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 2
- Phase 3
- 8
- Phase 4
- 4
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 12 · Other 5
Organon and Co (11) · Mahidol University (2) · University of Palermo (1) · Theramex (1) · Sydney Centre for Reproductive Health Research (1) · Catholic University of the Sacred Heart (1)
Often tested with
Tested in the same studies.
Estradiol (13) · Ethinyl Estradiol (2) · Etonogestrel (1) · Drospirenone (1) · Estetrol (1) · Dienogest (1) · Gestodene (1) · Drospirenone and ethinyl estradiol combination (1)
Studies
Open first, then newest update. How each study uses nomegestrol acetate is read from its arms, and is right about nine times in ten.
Testing it · 17
- Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral ContraceptiveTerminatedPhase 3Organon and CoNCT05264506Written as NOMAC-E2 COC
- Study of the Contraceptive Efficacy and Safety of a NOMAC-E2 Combined Oral Contraceptive (COC)(P06448)TerminatedPhase 3Organon and CoNCT01656434Written as NOMAC-E2
- A Dose-Finding Study to Evaluate Ovarian Function and Vaginal Bleeding in Next Generation Rings (P06109/MK-8175A/MK-8342B-012)CompletedPhase 2Organon and CoNCT01709318Written as Nomegestrol acetate (NOMAC)
- The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial PreparationCompletedPhase 4University of PalermoNCT06324851Written as Nomegestrol Acetate / Estradiol
- Efficacy and Safety of Oral NOMAC-E2 in Indian Women (P07057/MK-8175A-017)WithdrawnPhase 3Organon and CoNCT01723579Written as Nomegestrol acetate (NOMAC)
- Efficacy and Safety Study of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing DRSP/EE (292002)(P05722)CompletedPhase 3Organon and CoNCT00413062Written as NOMAC-E2
- Effects on Hemostasis, Lipids, Carbohydrate Metabolism, Adrenal & Thyroid Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG-EE (292004)(COMPLETED)(P05764)CompletedPhase 3Organon and CoNCT00511355Written as NOMAC-E2
- Bioequivalence of Nomegestrol Acetate (NOMAC) and Estradiol (E2) in Commercial Versus Phase 3 Pivotal Clinical Batches of NOMAC-E2 Tablets (P06328)CompletedPhase 1Organon and CoNCT01345786Written as Commercial NOMAC-E2
- Effects on Bone Mineral Density (BMD) of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG/EE (292005)(P05765)(COMPLETED)CompletedPhase 3Organon and CoNCT00511342Written as NOMAC-E2
- Efficacy and Safety of the Combined Oral Contraceptive (COC) NOMAC-E2 Compared to a COC Containing DRSP/EE (292001)(COMPLETED)(P05724)CompletedPhase 3Organon and CoNCT00511199Written as NOMAC-E2
- Effects on Ovarian Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing DRSP/EE (292003)(COMPLETED)(P05723)CompletedPhase 3Organon and CoNCT00511433Written as NOMAC-E2
- A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)CompletedPhase 1Organon and CoNCT00711607Written as nomegestrol acetate and estradiol
- Comparison of Coagulation Profiles Between Zoely and Minidoz: RCTTerminatedPhase 4Mahidol UniversityNCT03531437Written as 1.5 mg estradiol and 2.5 mg nomegestrol acetate
- Ovulation and Follicular Development Associated With Mid Follicular Phase Initiation of Combined Hormonal ContraceptionCompletedPhase 4Mahidol UniversityNCT03077555Written as Zoely
- A New Treatment Option for Heavy Menstrual BleedingStatus unknownPhase 4Sydney Centre for Reproductive Health ResearchNCT01715025Written as E2Nomac
- Effects of Drospirenone-ethinylestradiol and/or NOMAC-valerate Estradiol on Cardiovascular Risk in Women With Polycystic Ovary SyndromeStatus unknownPhase 1Catholic University of the Sacred HeartNCT01603745Written as Zoely
- Minimal Effective Dose of Nomegestrol Acetate Inhibiting the Ovulation in Women Receiving EstradiolCompletedPhase 2TheramexNCT01361958Written as NOMAC
Given in every arm · 1 — nomegestrol acetate is usual care beside what is tested
Codes
What other systems call nomegestrol acetate · ClinicalTrials.gg INT003100
- MeSH (NLM) C038501nomegestrol acetateOne source NLM
- UNII (FDA) 83J78V5W05NOMEGESTROL ACETATEConfirmed FDA, NLM, Wikidata
- RxNorm 53744Confirmed FDA, Wikidata
- Wikidata Q7048519nomegestrol acetateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C87244Nomegestrol AcetateOne source FDA
- DrugBank DB13981One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C038501 | nomegestrol acetate | One source NLM |
| UNII (FDA) | 83J78V5W05 | NOMEGESTROL ACETATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 53744 | — | Confirmed FDA, Wikidata |
| Wikidata | Q7048519 | nomegestrol acetate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C87244 | Nomegestrol Acetate | One source FDA |
| DrugBank | DB13981 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.