Mifepristone: all 148 studies that test it

Page 1 of 2. Open to participants first (9), then studies with results posted, then the rest; newest registration first within each.

• Period Pills for Menstrual Regulation: A New Reproductive Health OptionRecruitingNCT07671989Phase 4
• Optimal Time Interval Between Mifepristone and Misoprostol Administration for Early Pregnancy LossNot yet recruitingNCT07506512Phase 3
• Letrozole Versus Mifepristone and Misoprostol in Silent MiscarriageNot yet recruitingNCT06733727Not applicable
• REVERSE: Improving Treatment-resistant Post Traumatic Stress Disorder (PTSD) with Glucocorticoid Receptor (GR) AntagonismRecruitingNCT06689254Phase 2
• Mifepristone vs MisoprostolRecruitingNCT06502158Phase 1
• A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast CancerRecruitingNCT06099769Phase 2
• To Prevent Type I-II Myoma After TCRM Recurrence by Gonadotropin-releasing Hormone (GnRH )Analogues or MifepristoneNot yet recruitingNCT05898321Not applicable
• Mifepristone Outpatient Labour InductionRecruitingNCT05177510Phase 2
• Reverse Triple Negative Immune Resistant Breast CancerRecruitingNCT05076682Phase 2
• Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled TrialCompletedNCT05322252Phase 4Results posted
• Mifepristone for Labor InductionCompletedNCT05097326Phase 3Results posted
• Mifepristone Dynamic Testing for Diagnosis for Central Adrenal InsufficiencyTerminatedNCT04588688Phase 2Results posted
• Mail Order Mifepristone StudyCompletedNCT03913104Phase 4Results posted
• Cervical Preparation With Mifepristone Prior to Osmotic DilatorsTerminatedNCT03714880Phase 2Results posted
• Medication Abortion Via Pharmacy DispensingCompletedNCT03320057Phase 4Results posted
• Efficacy of Mifepristone in Males With Type 2 Diabetes MellitusTerminatedNCT03052400Phase 2Results posted
• INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy DrinkersCompletedNCT02989662Phase 1/2Results posted
• Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast CancerActive, not recruitingNCT02788981Phase 2Results posted
• Mifepristone Induction for Fetal DemiseTerminatedNCT02620904Phase 4Results posted
• Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical PreparationCompletedNCT02412618Phase 4Results posted
• Mifepristone Treatment of Alcohol Use DisorderCompletedNCT02179749Phase 2Results posted
• Comparative Effectiveness of Pregnancy Failure Management RegimensCompletedNCT02012491Phase 3Results posted
• Enzalutamide and Mifepristone in Treating Patients With Metastatic Hormone Resistant Prostate CancerCompletedNCT02012296Phase 1/2Results posted
• Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal HypercortisolismCompletedNCT01990560Phase 4Results posted
• Pre-Operative Effects of Mifepristone on Dilation and Evacuation ServicesCompletedNCT01862991Not applicableResults posted
• Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of MifepristoneCompletedNCT01739335Phase 2Results posted
• Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 WeeksTerminatedNCT01636063Not applicableResults posted
• Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety DisordersCompletedNCT01631682Phase 4Results posted
• Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 WeeksCompletedNCT01615731Not applicableResults posted
• Medication Development in Alcoholism: Investigating Glucocorticoid AntagonistsCompletedNCT01548417Phase 2Results posted
• Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) TreatmentsCompletedNCT01490697Phase 4Results posted
• Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 WeeksCompletedNCT01436279Phase 3Results posted
• Mifepristone Effects on Glucose Intolerance in Obese/Overweight AdultsCompletedNCT01419535Phase 1/2Results posted
• Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's SyndromeCompletedNCT01371565Phase 3Results posted
• Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety DisordersCompletedNCT01333098Phase 1/2Results posted
• Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained MenCompletedNCT01294319Phase 2Results posted
• Preliminary Trial of the Effect of Glucocorticoid Receptor Antagonist on Borderline Personality Disorder (BPD)TerminatedNCT01212588Phase 2Results posted
• Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent PatientsCompletedNCT01134198Phase 2/3Results posted
• Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 WeeksCompletedNCT00986921Not applicableResults posted
• An Extension Study of CORLUX in the Treatment of Endogenous Cushing's SyndromeCompletedNCT00936741Phase 3Results posted
• Treatment of Psychotic Major Depression With MifepristoneTerminatedNCT00867360Phase 3Results posted
• Compassionate Use of Mifepristone in Brain/Nervous System and Other CancersTerminatedNCT00832871Not applicableResults posted
• Treatment of Schizoaffective Disorder Using MifepristoneTerminatedNCT00725270Phase 2/3Results posted
• A 4-week Study of Mifepristone in the Prevention of Risperidone-induced Weight Gain in Healthy Male VolunteersCompletedNCT00698022Phase 1Results posted
• A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic FeaturesTerminatedNCT00637494Phase 3Results posted
• A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's SyndromeCompletedNCT00569582Phase 3Results posted
• MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy FailureTerminatedNCT00468299Not applicableResults posted
• Mifepristone in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT00459290Phase 2Results posted
• Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) SecretionTerminatedNCT00422201Phase 2Results posted
• Antiviral Activity and Safety of Mifepristone at 2 Doses in HIV-1 Infected SubjectsCompletedNCT00352911Phase 2Results posted
• Mifepristone Treatment for Patients With Non-psychotic Major Depressive Disorder Receiving Bilateral ECTCompletedNCT00285818Not applicableResults posted
• Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected PatientsCompletedNCT00255177Phase 2Results posted
• Mifepristone in Refractory DepressionCompletedNCT00186056Not applicableResults posted
• Trial of Mifepristone for FibroidsCompletedNCT00133705Phase 3Results posted
• Surgical vs. Medical Abortion on Sexual Function After Early Pregnancy LossCompletedNCT07646275Not applicable
• Endometrial Transcript Profile with Progesterone After Post-ovulatory MifepristoneCompletedNCT06616077Early Phase 1
• Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a ContraceptiveActive, not recruitingNCT06394999Phase 3
• Study to Determine the Prevalence of Hypercortisolism in Patients With Type 2 Diabetes and Treatment With Korlym® (Mifepristone) (CATALYST)CompletedNCT05772169Phase 4
• RESET-medication Glucocorticoid Receptor (GR) Blockade As Disease Modifying Treatment for Depression with Childhood TraumaCompletedNCT05217758Phase 2
• Long-term Use of Mifepristone in the Treatment of AdenomyosisStatus unknownNCT05151016Early Phase 1
• Comparison of Two Different Drug Regimens for Medical Treatment of Early Pregnancy LossStatus unknownNCT05124314Phase 4
• Assessing Outpatient 'Day Procedure' for Second-trimester Medical Abortion at Two Public Sector Hospitals in NepalCompletedNCT05046041Phase 4
• Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.Status unknownNCT05016349Phase 3
• Assessing Use Of Mifepristone After Progestin Priming For Use As "Missed Period Pills"Status unknownNCT04676776Phase 2
• Improving Access to Abortion in the Republic of GeorgiaStatus unknownNCT04458558Phase 4
• Understanding GWI: Integrative ModelingStatus unknownNCT04255498Phase 1
• TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis ResetCompletedNCT04254627Phase 1
• Pilot Study of an Ambulatory Medical Abortion Service at 13-18 Weeks of Gestation in ColombiaTerminatedNCT04063904Phase 4
• Assessing Medical Menstrual Regulation in the United StatesStatus unknownNCT03972358Phase 2
• Advance Provision of Medication AbortionWithdrawnNCT03829696Phase 4
• Evaluation of Therapeutic Effect and Safety of Mifepristone in the Treatment of AdenomyosisCompletedNCT03520439Phase 2/3
• Outpatient Service for Mid-trimester Termination of PregnancyCompletedNCT03346629Phase 4
• Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina FasoStatus unknownNCT03269279Phase 3
• Mifepristone Drug-Drug Interaction Study With CYP3A InhibitorCompletedNCT03259542Phase 1
• Crossover Drug-Drug Interaction Study to Determine Effects of Cytochrome P450 3A on Exposure to Mifepristone and Its MetabolitesCompletedNCT03258372Phase 1
• Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast CancerTerminatedNCT03225547Phase 2
• Comparing Two Medical Treatments for Early Pregnancy Failure.TerminatedNCT03212352Phase 4
• A Study on the Mifepristone Tablets in the Treatment of Symptomatic Uterine Fibroids With Safety and EfficacyTerminatedNCT03210324Phase 4
• Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed MiscarriageCompletedNCT03065660Phase 3
• Mifepristone and Misoprostol Compared With Misoprostol Alone for Second Trimester AbortionStatus unknownNCT03044093Phase 4
• S9005 Mifepristone in MeningiomaCompletedNCT03015701Phase 3
• Acceptability and Feasibility of Medical Abortion in SingaporeCompletedNCT02985229Phase 3
• Acceptability and Feasibility of a Simplified Medical Abortion Service Delivery in Western UkraineCompletedNCT02981030Phase 4
• Medical Abortion at Gestational Age of 8 to ≤9 Weeks Versus >9 to ≤12 WeeksStatus unknownNCT02745093Phase 4
• A Pilot of an Outpatient Regimen of Medical Abortion With Mifepristone and Sublingual Misoprostol in the 11 and 12 WeeksCompletedNCT02720991Phase 4
• Non-surgical Alternatives to Treatment of Failed Medical AbortionTerminatedNCT02704481Phase 4
• Mifepristone Versus Osmotic Dilators in Conjunction With Misoprostol for Cervical Preparation Prior to D&E at 14-19 WeeksWithdrawnNCT02679092Not applicable
• Mifepristone for Breast Cancer Patients With Higher Levels of Progesterone Receptor Isoform A Than Isoform B.CompletedNCT02651844Not applicable
• Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung CancerTerminatedNCT02642939Phase 2
• Mifepristone-misoprostol vs. Misoprostol Alone for Second Trimester Fetal DeathTerminatedNCT02633761Phase 3
• Short-Term Oral Mifepristone for Central Serous ChorioretinopathyCompletedNCT02354170Phase 2
• Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled TrialTerminatedNCT02342002Phase 4
• Mifepristone 2.5, 5, 10 mg Versus Placebo in the Treatment of EndometriosisCompletedNCT02271958Phase 2/3
• Medication Enhanced Rapid TherapyTerminatedNCT02099825Phase 1
• Carboplatin, Gemcitabine Hydrochloride, and Mifepristone in Treating Patients With Advanced Breast Cancer or Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT02046421Phase 1
• Mifepristone and Eribulin in Patients With Metastatic Triple Negative Breast Cancer or Other Specified Solid TumorsCompletedNCT02014337Phase 1
• Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older IndividualsCompletedNCT01988610Phase 1
• Pretreatment With Mifepristone Prior to Mirena InsertionCompletedNCT01931657Phase 2
• Mifepristone in Children With Refractory Cushing's DiseaseWithdrawnNCT01925092Phase 3
• BRCA1/2 and Effect of Mifepristone on the BreastCompletedNCT01898312Phase 2

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