Methotrexate: all 649 studies that test it
Page 5 of 7. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.
- Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe PsoriasisTerminatedNCT02829424Phase 4
- Pegaspargase and Methotrexate Based Regimens for Newly Diagnosed Extranodal NK/T Cell LymphomaCompletedNCT02825147Phase 2
- Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic LeukemiaCompletedNCT02779283Phase 1
- CNS Prophylaxis in Diffuse Large B-cell LymphomaStatus unknownNCT02777736Phase 3
- Clinical Trial to Evaluate Efficacy and Safety of Acellbia® (JSC "BIOCAD") With Methotrexate in First Line Biological Therapy of Patients With Active Rheumatoid ArthritisCompletedNCT02744196Phase 3
- Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For LymphomaWithdrawnNCT02724904Phase 1/2
- Pharmacogenomics Study on Treatment of Psoriasis Vulgaris by MethotrexateStatus unknownNCT02715947Phase 2
- The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic PregnancyCompletedNCT02714998Not applicable
- Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy SubjectsCompletedNCT02699710Phase 1
- A Study to Evaluate the Efficacy and Safety of Mabthera Alone and in Combination With Either Cyclophosphamide or Methotrexate in Patients With Rheumatoid ArthritisCompletedNCT02693210Phase 2
- Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia PatientsStatus unknownNCT02690922Phase 4
- Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic SyndromeTerminatedNCT02676323Phase 1
- Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALLStatus unknownNCT02660762Phase 2
- Comparison Study of Psoriasis Severity Assessment ToolsCompletedNCT02655705Phase 4
- Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm StudyStatus unknownNCT02644044Early Phase 1
- Different Dose of Methotrexate for the Treatment of Meningeal CarcinomatosisStatus unknownNCT02590510Phase 4
- Comparison of Compliance and Evolution of Functional Capacity of Patients With Rheumatoid Arthritis Treated by Methotrexate Either by Auto-injector or by Conventional Sub-cutaneous SyringeCompletedNCT02553018Phase 3
- Immune Modulation Therapy for Pompe DiseaseStatus unknownNCT02525172Phase 4
- Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid ArthritisCompletedNCT02480946Phase 1
- Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain TumorsCompletedNCT02458339Phase 1
- Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy PatientsCompletedNCT02456844Phase 1
- Methotrexate and Cytosine in Adult Langerhans Cell HistiocytosisCompletedNCT02389400Phase 2
- Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in ChildrenStatus unknownNCT02339350Phase 2
- Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell LymphomasTerminatedNCT02323659Phase 4
- Topical Steroids Alone or Associated With Methotrexate in Bullous PemphigoidCompletedNCT02313870Phase 3
- Maintenance Treatment Versus Observation in Elderly Patients With PCNS LymphomaStatus unknownNCT02313389Phase 3
- Low Dose Metronomic Poly-chemotherapy for Metastatic CRCCompletedNCT02280694Phase 2
- Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose EscalationCompletedNCT02269358Phase 4
- Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study.Status unknownNCT02248792Phase 4
- Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic SyndromeCompletedNCT02212561Phase 1
- LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell HistiocytosisActive, not recruitingNCT02205762Phase 2/3
- A proSpective Randomized Controlled Trial comParing infliximAb-antimetabolites Combination Therapy to Anti-metabolites monotheRapy and Infliximab monothErapy in Crohn's Disease Patients in Sustained Steroid-free Remission on Combination TherapyCompletedNCT02177071Phase 4
- Safety and Preliminary Efficacy Study of V404 PDS in UveitisTerminatedNCT02125266Phase 1/2
- Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe AsthmaStatus unknownNCT02124226Phase 3
- Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic MalignanciesCompletedNCT02122081Phase 1
- Bioavailability in Patient With Psoriasis: Metoject Prefilled PenCompletedNCT02097173Phase 1
- Inflammation Control For Elders: ICE StudyWithdrawnNCT02079948Phase 2
- Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis PatientsCompletedNCT02076659Phase 1
- RCT of Methotrexate Added to Treatment As Usual in SchizophreniaCompletedNCT02074319Phase 1
- Clinical Guidelines for APL TreatmentStatus unknownNCT02020161Phase 4
- Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic MalignanciesCompletedNCT02011022Not applicable
- RCT on the Efficacy of Methotrexate for the Prevention of GTDCompletedNCT01984099Phase 3
- Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes LeukemiaCompletedNCT01976182Phase 2
- Methotrexate in the Treatment of Chronic Idiopathic UrticariaCompletedNCT01960283Phase 3
- Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008Status unknownNCT01953770Not applicable
- A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic LeukemiaActive, not recruitingNCT01920737Phase 2
- Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)CompletedNCT01895764Phase 4
- A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of MethotrexateCompletedNCT01884636Phase 1
- A Study of The Effect of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate on Articular Damage in The Hand in Patients With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response to Non-Biological DMARDsWithdrawnNCT01878318Phase 4
- Effectiveness Of Expectant Management In The Tubal Ectopic PregnancyCompletedNCT01876004Phase 4
- Long-Term Efficacy and Safety of CT-P10 in Patients With RACompletedNCT01873443Phase 1
- Evaluation of Patient Performance Using the Metoject Device for Subcutaneous Injection in Rheumatoid Arthritis (RA)PatientCompletedNCT01871961Phase 1
- A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate TherapyTerminatedNCT01862224Phase 2
- BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment SuccessStatus unknownNCT01860690Phase 4
- the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia PatientStatus unknownNCT01766375Phase 3
- Dose Adjusted EPOCH-R, to Treat Mature B Cell MalignanciesCompletedNCT01760226Early Phase 1
- A Clinical Research on the Relation of Blood Drug Concentration and Calcium Folinate Rescued in High-dose MTX TherapyStatus unknownNCT01758666Not applicable
- A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid ArthritisCompletedNCT01754805Phase 1
- CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell LymphomaStatus unknownNCT01746992Phase 4
- Efficacy and Safety Study of Tacrobell to Treat Rheumatoid ArthritisCompletedNCT01746680Phase 4
- The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial)Status unknownNCT01741558Phase 2
- Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot StudyCompletedNCT01737671Early Phase 1
- Maintenance Metronomic Chemotherapy for Metastatic Colorectal CarcinomaTerminatedNCT01668680Phase 2
- Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging StudyTerminatedNCT01659242Phase 4
- Methotrexate in Symptomatic Knee OsteoarthritisCompletedNCT01654575Not applicable
- Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial CancerWithdrawnNCT01639521Phase 2
- Methotrexate for Central Serous Chorioretinopathy Treatment TrialStatus unknownNCT01633983Phase 2
- Efficacy and Safety of Tripterygium Wilfordii in Patients With Rheumatoid ArthritisCompletedNCT01613079Phase 2/3
- Low Dose Chemotherapy With Aspirin in Patients With Breast Cancer After Neoadjuvant ChemotherapyStatus unknownNCT01612247Not applicable
- Long-term Efficacy of Iguratimod Alone or Iguratimod in Combination With Methotrexate in Patients With Rheumatoid ArthritisStatus unknownNCT01548001Phase 4
- Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk PatientsCompletedNCT01516580Phase 3
- A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis ParticipantsCompletedNCT01450982Phase 1
- A Study to Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis ParticipantsCompletedNCT01442545Phase 1
- Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal DiseaseWithdrawnNCT01438021Not applicable
- Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis PatientsCompletedNCT01347983Phase 3
- A Clinical Trial Using Metronomic Oral Low-dose Cyclophosphamide Alternating With Low-dose Oral Methotrexate With Continuous Celecoxib and Weekly Vinblastine in Children and Adolescents With Relapsed or Progressing soliD Tumours.CompletedNCT01285817Phase 2
- Study of Tocilizumab in Combination With Methotrexate for Treatment of Moderate to Severe Rheumatoid Arthritis PatientsCompletedNCT01258712Phase 3
- Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter TrialStatus unknownNCT01240850Phase 3
- Hematopoietic Stem Cell Transplantation for MucopolysaccharidosisStatus unknownNCT01238328Phase 2/3
- Neoadjuvant Doxorubicin, Polyglutamate Paclitaxel, Capecitabine and Metronomic Chemotherapy in Breast CancerWithdrawnNCT01227408Phase 2
- Dose Ranging Study to Compare the Efficacy and Safety of Methotrexate in Plaque Type PsoriasisCompletedNCT01187264Phase 4
- Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment StrategyTerminatedNCT01175772Phase 2
- High-dose Chemotherapy and Stem Cell Transplantation for Central Nervous System (CNS) Relapse of Aggressive LymphomasStatus unknownNCT01148173Phase 2
- Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After DiscontinuationCompletedNCT01120366Phase 4
- Hematopoietic Stem Cell Transplantation for Malignant Infantile OsteopetrosisStatus unknownNCT01087398Phase 2/3
- Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT01085617
- Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus PlaceboCompletedNCT01068405Phase 3
- Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast CancerTerminatedNCT01067989Phase 2
- Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid MalignanciesCompletedNCT01056614Phase 2
- Combination Disease-Modifying Antirheumatic Drugs (DMARDs) Versus Sulfasalazine in Inflammatory Back PainCompletedNCT01040195Phase 3
- Cyclophosphamide, Methotrexate, and Fluorouracil, With or Without Epirubicin Hydrochloride, in Treating Women Who Have Undergone Surgery for Breast Cancer (Group III Closed to New Patients as of 12/7/2009)Status unknownNCT01031030Phase 3
- Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in RemissionCompletedNCT01020734Phase 2
- Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic ArthritisCompletedNCT01015547Phase 3
- SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid ArthritisCompletedNCT01010581Phase 2
- Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell TransplantationCompletedNCT00993343Phase 3
- GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy SubjectsCompletedNCT00989703Phase 1
- Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-LymphomaStatus unknownNCT00989352Phase 2
- A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid ArthritisCompletedNCT00965653Phase 1
- Methotrexate in Metastatic Colorectal Cancer With MSH2 DeficiencyTerminatedNCT00952016Phase 2
- Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's DiseaseStatus unknownNCT00931957Not applicable