Methotrexate: all 649 studies that test it
Page 4 of 7. Open to participants first (88), then studies with results posted, then the rest; newest registration first within each.
- Impact of Selenium on Methotrexate Induced Spermatotoxicity; A Comparative StudyCompletedNCT06951282Phase 1/2
- Local Methotrexate Injections for the Treatment of Nail PsoriasisTerminatedNCT06578728Phase 4
- Phase I Study Evaluating Tolerability, Safety, Pharmacokinetics, and Efficacy of Combined ONO-4059 and R-MPV Therapy for PCNSLActive, not recruitingNCT06541665Phase 1
- Comparison of the Effectiveness of Single-Dose Methotrexate Protocol With Letrozole + Single-Dose Methotrexate in the Medical Treatment of Patients Diagnosed With Ectopic PregnancyCompletedNCT06504082Not applicable
- Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS MalignanciesWithdrawnNCT06466798Phase 1
- Methotrexate Infusion and Intrasilicone Injection During Diabetic VitrectomyCompletedNCT06038968Early Phase 1
- Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for HypophosphatasiaWithdrawnNCT06015750Phase 4
- Methotrexate for Immune Related Arthritis or Arthralgias (IMPACT 2.1)TerminatedNCT06001125Phase 2
- Assessment of the Efficacy of Letrozole in the Treatment of Ectopic PregnancyStatus unknownNCT05918718Phase 1/2
- Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell ArteritisActive, not recruitingNCT05623592Phase 2
- A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy ParticipantsCompletedNCT05615012Phase 1
- A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)TerminatedNCT05600426Phase 3
- A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy SubjectsCompletedNCT05575297Phase 1
- Orelabrutinib,Rituximab and Methotrexate in Newly-diagnosed Primary Central Nervous System Lymphoma(PCNSL)Status unknownNCT05549284Phase 2
- MAD Study of IA-14069CompletedNCT05533372Phase 1
- Methotrexate Combined With Immunotherapy During Radiotherapy for Solid TumorsActive, not recruitingNCT05522582Phase 2
- Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingNCT05457556Phase 3
- A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of SulfasalazineCompletedNCT05445440Phase 1
- Thyroid Associated Orbitopathy Treatment by Methotrexate Against Triamcinolone Periocular InjectionsCompletedNCT05429450Phase 2
- Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum Chitotriosidase Level in PsoriasisStatus unknownNCT05427175Phase 4
- RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSLStatus unknownNCT05425654Phase 2
- R-MTX-zanbrutinib in Secondary CNS LymphomaStatus unknownNCT05398224Phase 2
- A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy SubjectsCompletedNCT05380934Phase 1
- Methotrexate in Patients with Early Rheumatoid ArthritisActive, not recruitingNCT05353829Phase 4
- Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin CancersCompletedNCT05315128Phase 2
- MTX Hold During Covid-19 BoosterStatus unknownNCT05313061Phase 3
- Medical Treatment in Ectopic Tubal PregnancyCompletedNCT05208034Not applicable
- Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14.Status unknownNCT05049473Phase 2
- A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSLCompletedNCT05036577Phase 1
- Fractional CO2 Laser-assisted Cutaneous Delivery of Methotrexate Versus 5-fluorouracil in Stable Non-segmental VitiligoStatus unknownNCT05008887Phase 4
- Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and LeukemiaWithdrawnNCT04961801Phase 1/2
- MTX and Steroid as First-line Therapy for aGVHDCompletedNCT04960644Phase 3
- MTX and Steroid for III-IV aGVHD TreatmentStatus unknownNCT04958538Phase 2
- Rituximab,Methotrexate and Lenalidomide in Newly Diagnosed Primary Central Nervous System LymphomaCompletedNCT04934579Phase 2
- Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRLStatus unknownNCT04899453Phase 2
- Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaWithdrawnNCT04845035Phase 2
- Ruxolitinib With Calcineurin Inhibitor and Methotrexate vs. Calcineurin Inhibitor Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell TransplantationCompletedNCT04838704Not applicable
- Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric PatientsWithdrawnNCT04830878Phase 1
- Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum TWEAK Level in PsoriasisStatus unknownNCT04811911Phase 4
- MTX and Steroid for aGVHD TreatmentStatus unknownNCT04677868Phase 2
- Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS LymphomaActive, not recruitingNCT04609046Phase 1
- Adalimumab Plus Methotrexate for the Treatment of Pediatric UveitisStatus unknownNCT04588818Phase 2
- Methotrexate in Erosive Inflammatory Hand OsteoarthritisActive, not recruitingNCT04579848Phase 4
- Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic NeoplasiaActive, not recruitingNCT04562558Not applicable
- A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological MalignanciesActive, not recruitingNCT04547049Phase 3
- Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal PolyposisCompletedNCT04532736Phase 2
- Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in AdultsActive, not recruitingNCT04530565Phase 3
- Ibrutinib With Methotrexate and Temozolomide for Patients With Newly Diagnosed Primary CNS LymphomaStatus unknownNCT04514393Phase 2
- Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH)Active, not recruitingNCT04483466Phase 3
- Repeated Methotrexate for Proliferative Vitreoretinopathy Grade CStatus unknownNCT04482543Phase 2/3
- Tofacitinib Versus Methotrexate as the First Line DMARD in the Treatment of Rheumatoid ArthritisStatus unknownNCT04464642Phase 4
- Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar PregnancyStatus unknownNCT04379219Phase 4
- Effect of Two Methotrexate in Sync With the First Adalimumab to Prevent the Immunisation Anti Ada in SpondyloarthritisCompletedNCT04360785Not applicable
- Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 PatientsStatus unknownNCT04352465Phase 1/2
- Effectiveness of Methotrexate Versus Prednisone as First-line Therapy for Pulmonary SarcoidosisActive, not recruitingNCT04314193Phase 4
- A Study Assessing the Efficacy and Safety of SM03 in Patients With Active Rheumatoid Arthritis Receiving MTXStatus unknownNCT04312815Phase 3
- The Aromatase Inhibitor and Gnrh Antagonist Versus Methotrexate for Management of Undisturbed Ectopic PregnancyStatus unknownNCT04308343Not applicable
- A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677CompletedNCT04268394Phase 1
- Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive VitiligoCompletedNCT04237103Phase 2
- Clinical Comparative Study to Evaluate the Efficacy and Safety of Recombinant Anti-TNF-alpha Antibodies for InjectionStatus unknownNCT04178850Phase 3
- Tocilizumab REMission in Early RACompletedNCT04157010Phase 4
- Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell TransplantationActive, not recruitingNCT04018937Phase 2
- Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitisCompletedNCT03815448Not applicable
- Methotrexate and Prednisolone Study in Erythema Nodosum LeprosumActive, not recruitingNCT03775460Not applicable
- Early Systemic Central Nervous System Prophylaxis in Diffuse Large B-cell LymphomaWithdrawnNCT03719560Phase 2
- The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in ChildrenStatus unknownNCT03692416Phase 3
- PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease ProphylaxisStatus unknownNCT03689465Phase 4
- Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell TransplantationWithdrawnNCT03602898Phase 2
- Molecular Profile of Breast Cancer in Ugandan Patients With Stage IIB-III Breast CancerCompletedNCT03518242Phase 1
- Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMITerminatedNCT03516903Phase 2/3
- Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous SystemCompletedNCT03495960Phase 2
- Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe PsoriasisStatus unknownNCT03408756Phase 4
- A Study to Investigate BMS-986165 and Methotrexate in Healthy Male PatientsCompletedNCT03402087Phase 1
- To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With CorticosteroidsCompletedNCT03371667Phase 3
- Add-on Methotrexate for the Treatment of SchizophreniaStatus unknownNCT03369795Phase 2
- Efficacy, Safety and Immunogenicity of Enerceptan Compared to Enbrel in Rheumatoid ArthritisCompletedNCT03332719Phase 3
- Effect of Methotrexate on Inflammatory Response in Adult Atopic Dermatitis PatientsCompletedNCT03327116Not applicable
- Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)Status unknownNCT03321890Phase 2
- Methotrexate, Blood Pressure and Arterial Function in Rheumatoid ArthritisCompletedNCT03254589Phase 4
- Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With MethotrexateCompletedNCT03244462Phase 1
- MAP Study: Methotrexate and Adalimumab in PsoriasisCompletedNCT03217734Phase 2/3
- Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia MajorStatus unknownNCT03171831Phase 4
- An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) TherapyCompletedNCT03155347Phase 3
- Impact of Concomitant MTX on Efficacy, Safety and Adherence of Ustekinumab-treatment in Patients With Active PsACompletedNCT03148860Phase 3
- Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and PravastatinCompletedNCT03131973Phase 1
- High-dose Intravenous Methotrexate Versus Intrathecal Methotrexate for Central Nervous System Prophylaxis in DLBCLStatus unknownNCT03123718Phase 3
- Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingNCT03117751Phase 2/3
- Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's ArteritisCompletedNCT03096275Phase 3
- Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic OsteosarcomaStatus unknownNCT03063983Phase 2
- Efficacy of Starting Methotrexate Early in Chikungunya ArthritisCompletedNCT03058471Not applicable
- BE Study in Patients - Methotrexate TabletsStatus unknownNCT02940561Phase 1
- Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain TumorsCompletedNCT02905110Early Phase 1
- Trial in Patients With Psoriasis Treated With Methotrexate Using an Optimized Treatment Schedule (METOP)CompletedNCT02902861Phase 3
- 2-week dc of MTX and Influenza Vaccination in RAStatus unknownNCT02897011Not applicable
- Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified TreatmentCompletedNCT02881086Phase 3
- A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid ArthritisCompletedNCT02867306Phase 1
- Reduce Risk for Crohn's Disease PatientsCompletedNCT02852694Phase 4
- LBL-2016 for Children or Adolescents in ChinaActive, not recruitingNCT02845882Phase 3
- Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic AnemiaCompletedNCT02845596Not applicable
- Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid ArthritisStatus unknownNCT02837146Phase 3