Metformin: all 1,377 studies that test it

Page 4 of 14. Open to participants first (169), then studies with results posted, then the rest; newest registration first within each.

• Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer RiskCompletedNCT02028221Phase 2Results posted
• Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC)TerminatedNCT02019979Phase 2Results posted
• Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and GlimepirideCompletedNCT02007278Phase 4Results posted
• Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Compared With Single TabletsCompletedNCT01975220Phase 1Results posted
• Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral TherapyCompletedNCT01972724Phase 4Results posted
• Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial AdenocarcinomaCompletedNCT01968317Phase 2Results posted
• Effect of Insulin Sensitizer Metformin on AD BiomarkersCompletedNCT01965756Phase 2Results posted
• Two-way Crossover Study in Healthy Male and Female Subjects to Evaluate the Bioequivalence of Jentadueto®.CompletedNCT01947153Phase 1Results posted
• Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking MetforminCompletedNCT01929863Phase 2Results posted
• Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast CancerActive, not recruitingNCT01905046Phase 3Results posted
• Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery DiseaseTerminatedNCT01901224Phase 4Results posted
• Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 DiabetesCompletedNCT01890122Phase 3Results posted
• Metformin Therapy for Overweight Adolescents With Type 1 DiabetesCompletedNCT01881828Phase 3Results posted
• A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic WomenCompletedNCT01877564Phase 2Results posted
• Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)TerminatedNCT01876992Not applicableResults posted
• Safety of Continuing Metformin in Diabetic Patients With Normal Kidney Function Receiving Contrast MediaCompletedNCT01873859Not applicableResults posted
• Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 DiabetesCompletedNCT01864174Phase 4Results posted
• Metformin+Cytarabine for the Treatment of Relapsed/Refractory AMLTerminatedNCT01849276Phase 1Results posted
• Sitagliptin Therapy in Hospitalized Patients With Type 2 DiabetesCompletedNCT01845831Phase 4Results posted
• Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single TabletsCompletedNCT01845077Phase 1Results posted
• Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single TabletsCompletedNCT01844531Phase 1Results posted
• OXEMET™ 1000 mg Coated Tablets (Metformin Hydrochloride) Bioequivalence Study. OXEMET (TM) is a Trademark of the GlaxoSmithKline Group of Companies. GLAFORNIL(TM) is a Trademark of Merck.CompletedNCT01842620Phase 4Results posted
• Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)CompletedNCT01825798Phase 3Results posted
• Assessing the Efficacy, Safety, and Tolerability of Met DR in Subjects With T2DM Over 12 WeeksCompletedNCT01819272Phase 2Results posted
• Effect of Metformin on Vascular and Mitochondrial Function in Type 1 DiabetesCompletedNCT01813929Phase 4Results posted
• Equivalence of Resorption of Empagliflozin/Metformin Administered as Combination Tablet Compared With Empagliflozin/Metformin as Single Tablets Administered TogetherCompletedNCT01811953Phase 1Results posted
• A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and ExerciseCompletedNCT01809327Phase 3Results posted
• EMERALD: Effects of Metformin on Cardiovascular Function in Adolescents With Type 1 DiabetesCompletedNCT01808690Phase 3Results posted
• Assessing the Effect of Met DR on Plasma Glucose and PK in Subjects With T2DMCompletedNCT01804842Phase 1/2Results posted
• Metformin and Muscle in Insulin-resistant Older VeteransCompletedNCT01804049Phase 1/2Results posted
• A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial CarcinomaCompletedNCT01797523Phase 2Results posted
• Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) PatientsCompletedNCT01792830Phase 3Results posted
• RISE Adult Medication StudyCompletedNCT01779362Phase 3Results posted
• The Health Influences of Puberty (HIP) StudyCompletedNCT01775813Phase 4Results posted
• Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by MetforminCompletedNCT01766778Phase 4Results posted
• Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in HumansCompletedNCT01762046Phase 1Results posted
• A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)CompletedNCT01760447Phase 3Results posted
• A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLLCompletedNCT01750567Phase 2Results posted
• Effects of Metformin on Hepatic FFA MetabolismCompletedNCT01729156Phase 4Results posted
• Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 DiabetesCompletedNCT01719003Phase 3Results posted
• Metformin as a Chemoprevention Agent in Non-small Cell Lung CancerTerminatedNCT01717482Phase 2Results posted
• BE Study of Metformin GSK 500mgCompletedNCT01710527Phase 2Results posted
• Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 PatientsCompletedNCT01708902Phase 3Results posted
• A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)CompletedNCT01702298Phase 3Results posted
• An Endometrial Cancer Chemoprevention Study of MetforminCompletedNCT01697566Phase 3Results posted
• Demonstration of Bioequivalence of Empagliflozin and Metformin Given in One Tablet Compared to the Intake of Single TabletsCompletedNCT01672788Phase 1Results posted
• Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic CancerCompletedNCT01666730Phase 2Results posted
• Assessing the Behavior of Met DR in Subjects With Kidney DysfunctionCompletedNCT01658514Phase 2Results posted
• Effect of Metformin on Biomarkers of Colorectal Tumor Cell GrowthTerminatedNCT01632020Phase 2Results posted
• Exemestane-RAD001-MetforminTerminatedNCT01627067Phase 2Results posted
• Cavitation Ultrasound in Treatment of Patients With PCOSCompletedNCT01622257Phase 2Results posted
• Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate CancerCompletedNCT01620593Phase 2Results posted
• Metabolic Abnormalities in HIV-infected PersonsCompletedNCT01612858Phase 4Results posted
• Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus SubjectsCompletedNCT01589445Phase 4Results posted
• Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single TabletsCompletedNCT01581931Phase 1Results posted
• Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic PatientsCompletedNCT01579812Phase 2Results posted
• Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.TerminatedNCT01578551Phase 2Results posted
• A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)CompletedNCT01573949Not applicableResults posted
• A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)CompletedNCT01557504Phase 1Results posted
• Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)CompletedNCT01545388Phase 3Results posted
• Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /MetforminCompletedNCT01540487Phase 1Results posted
• Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DMTerminatedNCT01525225Phase 1Results posted
• Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on MetforminCompletedNCT01517412Phase 3Results posted
• Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 DiabetesCompletedNCT01512979Phase 4Results posted
• Metformin and Transient HyperglycemiaTerminatedNCT01486043Not applicableResults posted
• REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)CompletedNCT01483560Phase 3Results posted
• Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOSTerminatedNCT01482286Phase 3Results posted
• Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett EsophagusCompletedNCT01447927Phase 2Results posted
• Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing SurgeryCompletedNCT01433913Phase 2Results posted
• Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and ProgesteroneCompletedNCT01427595Not applicableResults posted
• Adipokines in Obese Adolescents With Insulin ResistanceCompletedNCT01410604Phase 4Results posted
• Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-BrazilCompletedNCT01365091Phase 1Results posted
• Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With ObesityTerminatedNCT01351753Phase 2Results posted
• Exercise and Metformin in Colorectal and Breast Cancer SurvivorsCompletedNCT01340300Phase 2Results posted
• Adjunctive Metformin Therapy in Double DiabetesCompletedNCT01334125Phase 3Results posted
• Prevention of Metabolic Complications of Glucocorticoid ExcessCompletedNCT01319994Phase 2/3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318135Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318109Phase 2/3Results posted
• Metformin for the Treatment of Premature Pubarche in GirlsTerminatedNCT01316042Not applicableResults posted
• Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMICompletedNCT01312467Phase 2Results posted
• A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast CancerCompletedNCT01310231Phase 2Results posted
• Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer SurvivorsCompletedNCT01302379Not applicableResults posted
• Efficacy and Safety of Alogliptin in Participants With Type 2 DiabetesCompletedNCT01289119Phase 3Results posted
• Metformin Postpartum for GDM RCT for Reduced Weight RetentionCompletedNCT01280409Phase 4Results posted
• Metformin Versus Insulin in Gestational DiabetesCompletedNCT01240785Phase 4Results posted
• Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)CompletedNCT01234649Phase 3Results posted
• Metformin to Reduce Heart Failure After Myocardial InfarctionCompletedNCT01217307Phase 2/3Results posted
• Relative Bioavailability of Two Different Batches of a Linagliptin / Metformin Combination Tablet in Healthy VolunteersCompletedNCT01216397Phase 1Results posted
• Metformin in Castration-Resistant Prostate CancerTerminatedNCT01215032Phase 2Results posted
• Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XRCompletedNCT01192152Phase 1Results posted
• Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)CompletedNCT01192139Phase 1Results posted
• Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial)CompletedNCT01181674Phase 4Results posted
• Metformin for Weight Loss in SchizophreniaTerminatedNCT01177709Not applicableResults posted
• Management of Diabetes With Metformin In Patients With Chronic Heart FailureCompletedNCT01122316Not applicableResults posted
• A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast CancerCompletedNCT01101438Phase 3Results posted
• Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin TreatmentCompletedNCT01099618Phase 4Results posted
• Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)CompletedNCT01093794Phase 1Results posted
• Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)CompletedNCT01076088Phase 3Results posted
• Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-AdministeredCompletedNCT01068743Phase 1Results posted
• Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy SubjectsCompletedNCT01068730Phase 1Results posted

← Metformin overview