Metformin: all 1,377 studies that test it

Page 5 of 14. Open to participants first (169), then studies with results posted, then the rest; newest registration first within each.

• A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178)CompletedNCT01034111Phase 3Results posted
• Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 DiabetesCompletedNCT01023581Phase 3Results posted
• Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)CompletedNCT00993187Phase 4Results posted
• Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy SubjectsCompletedNCT00986401Phase 1Results posted
• Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By SurgeryTerminatedNCT00984490Not applicableResults posted
• Metformin Compared to Glyburide in Gestational DiabetesCompletedNCT00965991Not applicableResults posted
• Pre-Surgical Study: Effect of Metformin on Breast Cancer ProliferationCompletedNCT00930579Phase 2Results posted
• Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)CompletedNCT00929201Phase 1Results posted
• Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg BidCompletedNCT00915772Phase 3Results posted
• Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (B)CompletedNCT00897390Phase 1Results posted
• Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes MellitusCompletedNCT00885378Phase 3Results posted
• Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 DiabetesCompletedNCT00859898Phase 3Results posted
• Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension TrialCompletedNCT00851903Phase 3Results posted
• Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, FastingCompletedNCT00836472Phase 1Results posted
• Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, FedCompletedNCT00835991Phase 1Results posted
• Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational DiabetesCompletedNCT00835861Phase 2Results posted
• Metformin ER 750 mg Tablets, FastingCompletedNCT00834743Phase 1Results posted
• Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and OverweightCompletedNCT00834652Phase 4Results posted
• Metformin ER 750 mg Tablets, FedCompletedNCT00834613Phase 1Results posted
• A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)CompletedNCT00830076Phase 1Results posted
• Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DMCompletedNCT00820573Phase 4Results posted
• Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering DrugsCompletedNCT00819741Phase 4Results posted
• The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)CompletedNCT00816907Phase 4Results posted
• Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With AntipsychoticsCompletedNCT00806234Phase 4Results posted
• Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial DesignCompletedNCT00798161Phase 3Results posted
• Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for SchizophreniaTerminatedNCT00794963Not applicableResults posted
• 12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic PatientsCompletedNCT00789035Phase 2Results posted
• Response To Oral Agents in Diabetes (ROAD)- Pilot StudyCompletedNCT00780715Phase 4Results posted
• Body Weight Effects on Glucophage's Efficacy in Chinese Diagnosed T2DM PatientsCompletedNCT00778622Phase 4Results posted
• Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.CompletedNCT00770653Phase 3Results posted
• Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)TerminatedNCT00736385Phase 4Results posted
• Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.CompletedNCT00727857Phase 3Results posted
• Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)CompletedNCT00714233Phase 3Results posted
• Pharmacogenetics of Metformin Action in PCOSCompletedNCT00703508Not applicableResults posted
• Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)TerminatedNCT00682890Phase 4Results posted
• Metformin for the Prevention of the Metabolic Side-effects of ZyprexaCompletedNCT00682448Phase 4Results posted
• Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone HealthCompletedNCT00679939Phase 4Results posted
• Metformin Versus Insulin in Pregnant Women With Type 2 DiabetesCompletedNCT00678080Not applicableResults posted
• Study of Brain Function in Women With Insulin Resistant Polycystic Ovary SyndromeCompletedNCT00670800Not applicableResults posted
• Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal InsulinCompletedNCT00669864Phase 4Results posted
• An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release TabletsCompletedNCT00643851Phase 3Results posted
• A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)CompletedNCT00631488Phase 2Results posted
• Metformin in Amnestic Mild Cognitive ImpairmentCompletedNCT00620191Phase 2Results posted
• EMPOWIR:Enhance the Metabolic Profile of Women With Insulin ResistanceCompletedNCT00618072Phase 2Results posted
• Strategies to Reduce Antipsychotic-Associated Weight Gain in YouthCompletedNCT00617240Phase 2Results posted
• Improving Metabolic Parameters of Antipsychotic Child Treatment With Ziprasidone, Aripiprazole, and ClozapineTerminatedNCT00617058Phase 2Results posted
• Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.CompletedNCT00570739Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Sitagliptin and MK0431A in Comparison to a Commonly Used Medication in Patients With Type 2 Diabetes (0431-068)(COMPLETED)CompletedNCT00541450Phase 3Results posted
• MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)CompletedNCT00532935Phase 3Results posted
• MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)CompletedNCT00482729Phase 3Results posted
• Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)CompletedNCT00473876Phase 4Results posted
• Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin ResistanceCompletedNCT00443755Phase 2Results posted
• Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With OlanzapineCompletedNCT00401973Phase 3Results posted
• Lifestyle Modification and Metformin Use in the Treatment of HIVCompletedNCT00399360Not applicableResults posted
• RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in DiabetesCompletedNCT00379769Phase 3Results posted
• Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 DiabetesCompletedNCT00367055Phase 4Results posted
• The LANCET Trial: A Trial of Long-acting Insulin Injection to Reduce C-reactive Protein in Patients With Type 2 DiabetesTerminatedNCT00366301Phase 4Results posted
• A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and ExerciseCompletedNCT00327015Phase 3Results posted
• 24-Hour Glycemia: Rosiglitazone Versus Glimepiride In Type 2 DiabetesCompletedNCT00318656Phase 4Results posted
• Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes MellitusCompletedNCT00286442Phase 3Results posted
• Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive TherapyCompletedNCT00283816Phase 3Results posted
• Preservation of Beta-cell Function in Type 2 Diabetes MellitusCompletedNCT00232583Not applicableResults posted
• Genetic Basis for Variation in the Renal Elimination of MetforminCompletedNCT00187720Phase 4Results posted
• Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy SubjectsCompletedNCT00187681Phase 4Results posted
• Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)CompletedNCT00151411Phase 2Results posted
• Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication InterventionCompletedNCT00139477Not applicableResults posted
• Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study)CompletedNCT00131664Phase 3Results posted
• Insulin Resistance and Testosterone in WomenCompletedNCT00123110Phase 2Results posted
• Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin AloneCompletedNCT00121667Phase 3Results posted
• The Effects of Metformin on Blood Vessel Structure and FunctionCompletedNCT00105066Phase 2Results posted
• MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)CompletedNCT00103857Phase 3Results posted
• Treatment of Nonalcoholic Fatty Liver Disease in Children (TONIC)CompletedNCT00063635Phase 3Results posted
• Treating Nonalcoholic Steatohepatitis (NASH) With MetforminCompletedNCT00063232Phase 2Results posted
• Diabetes Prevention Program Outcomes StudyCompletedNCT00038727Phase 3Results posted
• Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)CompletedNCT00032487Phase 3Results posted
• Metformin to Treat Obesity in Children With Insulin ResistanceCompletedNCT00005669Phase 2Results posted
• Action to Control Cardiovascular Risk in Diabetes (ACCORD)CompletedNCT00000620Phase 3Results posted
• Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release TabletsCompletedNCT07872358Phase 1
• Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary SyndromeCompletedNCT07811856Phase 4
• Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOSCompletedNCT07793838Phase 4
• Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary RegionCompletedNCT07770087Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNCT07763964Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fast Study.CompletedNCT07763951Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.CompletedNCT07763912Not applicable
• Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.CompletedNCT07763899Not applicable
• Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in JordanCompletedNCT07759674Phase 4
• Effects of Various Types of Ultrasound Therapy in Knee OsteoarthritisCompletedNCT07738692Not applicable
• Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mgCompletedNCT07694115Phase 1
• Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release TabletsCompletedNCT07691203Phase 1
• Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy SubjectsCompletedNCT07679711Phase 1
• Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy ObesityCompletedNCT07604870Phase 2
• Enhancing PCOS Management for Better Outcomes of Intracytoplasmic Sperm InjectionActive, not recruitingNCT07604779Not applicable
• Effect of NAE on Polycystic Ovarian Syndrome (PCOS)CompletedNCT07603505Phase 1
• Inositol in Letrozol Resistant PCOS WomenCompletedNCT07585396Phase 2/3
• A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.CompletedNCT07567781Phase 1
• Effects of Empagliflozin-Metformin, Sitagliptin-Metformin, and Metformin on Adipokines in Type 2 DiabetesCompletedNCT07531108Phase 4
• A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)CompletedNCT07530289Phase 1
• Combination Gerotherapeutic Interventions for Healthspan ImprovementActive, not recruitingNCT07475546Phase 3
• Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian SyndromeCompletedNCT07399535Phase 1
• Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat ObesityCompletedNCT07387679Not applicable

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