Lacosamide: all 90 studies that test it

Page 1 of 1. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.RecruitingNCT07412132Phase 3
• Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic NeuralgiaRecruitingNCT06969417Not applicable
• Seizure Prevention in Traumatic Brain Injury With Levetiracetam and LacosamideRecruitingNCT06866691Phase 4
• Lacosamide Versus Topiramate in MigraineRecruitingNCT06243692Phase 3
• Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With EpilepsyRecruitingNCT05969054Phase 4
• Antiseizure Medication in Seizure Networks at Early Acute Brain InjuryTerminatedNCT06081283Phase 4Results posted
• A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide TreatmentCompletedNCT04627285Phase 3Results posted
• A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal SeizuresTerminatedNCT04519645Phase 2Results posted
• Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD)CompletedNCT03897348Phase 2Results posted
• Seizure Prophylaxis in Patients With Glioma or Brain MetastasisTerminatedNCT03436433Phase 2Results posted
• Lacosamide Effects on Alcohol Self Administration and Craving in Heavy DrinkersCompletedNCT03271528Phase 1Results posted
• Study to Investigate Safety and Tolerability of Intravenous Lacosamide in Children.CompletedNCT02710890Phase 2/3Results posted
• A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994CompletedNCT02582866Phase 3Results posted
• Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ≥1 Month to <4 Years With Partial-onset SeizuresCompletedNCT02477839Phase 3Results posted
• Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic SeizuresCompletedNCT02408549Phase 3Results posted
• A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic MedicationsCompletedNCT02408523Phase 3Results posted
• Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset SeizuresCompletedNCT02192814Phase 3Results posted
• A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset SeizuresCompletedNCT02124564Phase 3Results posted
• A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.CompletedNCT01969851Phase 2Results posted
• A Clinical Study to Investigate the Efficacy and Safety of Lacosamide as an Add on Therapy in Children With Epilepsy With Partial-onset SeizuresCompletedNCT01964560Phase 3Results posted
• Study to Investigate Lacosamide as Add-on Therapy in Subjects ≥4 Years to <17 Years of Age With Partial Onset SeizuresCompletedNCT01921205Phase 3Results posted
• Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Adjunctive Therapy With Lacosamide in Adults With Partial-onset SeizuresCompletedNCT01832038Phase 3Results posted
• A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset SeizuresCompletedNCT01710657Phase 3Results posted
• eValuation of the Efficacy and toleRability of Vimpat When Added to lEvetiracetamCompletedNCT01484977Phase 3Results posted
• Evaluating Long Term Safety of Lacosamide (LCM) to Carbamazepine Controlled-release (CBZ-CR); Initial Monotherapy in Epilepsy Subjects 16 Years and OlderCompletedNCT01465997Phase 3Results posted
• Intravenous Lacosamide Compared With Fosphenytoin in the Treatment of Patients With Frequent Nonconvulsive SeizuresCompletedNCT01458522Phase 2Results posted
• Lacosamide in Preventing Seizures in Participants With Malignant GliomaTerminatedNCT01432171Not applicableResults posted
• Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to LacosamideTerminatedNCT01375374Phase 3Results posted
• Add on Lacosamide Versus High Dose MonotherapyCompletedNCT01345058Phase 3Results posted
• Trial Comparing the Efficacy and Safety of Lacosamide (LCM) to Carbamazepine Controlled-Release (CBZ-CR); Initial Monotherapy in Epilepsy; Subjects Aged 16 and OlderCompletedNCT01243177Phase 3Results posted
• Trial to Assess Optimized Dosage of Lacosamide as add-on Therapy in Patients With Partial Onset SeizureCompletedNCT01235403Phase 4Results posted
• Randomized Controlled Trial to Assess Effects of Lacosamide on Sleep and Wake in Adults With Focal EpilepsyCompletedNCT01190098Phase 4Results posted
• Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With EpilepsyCompletedNCT01118962Phase 2Results posted
• Open-Label Study to Assess Lacosamide Safety as Add-on Therapy for Primary Generalized Tonic-Clonic Seizures in Subjects With EpilepsyCompletedNCT01118949Phase 2Results posted
• A Pilot Study of NSICU Assessment of Seizure Prophylaxis With LacosamideTerminatedNCT01110187Not applicableResults posted
• Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset SeizuresCompletedNCT00955357Phase 4Results posted
• An Open-Label Study to Determine Safety , Tolerability, and Efficacy of Oral Lacosamide in Children With EpilepsyCompletedNCT00938912Phase 2Results posted
• A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial SeizuresCompletedNCT00938431Phase 2Results posted
• Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset SeizuresCompletedNCT00655551Phase 3Results posted
• Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset SeizuresCompletedNCT00655486Phase 3Results posted
• To Determine Tolerability and Efficacy of Long-term Oral Lacosamide in Patients With Partial SeizuresCompletedNCT00552305Phase 2Results posted
• Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.CompletedNCT00546351Phase 3Results posted
• Trial to Assess Long-term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-onset SeizuresCompletedNCT00530855Phase 3Results posted
• Determine Safety and Efficacy of Long-term Oral Lacosamide in Patients With Partial SeizuresCompletedNCT00522275Phase 3Results posted
• Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset SeizuresCompletedNCT00520741Phase 3Results posted
• Assess Safety and Efficacy of Lacosamide in Patients With Partial SeizuresCompletedNCT00515619Phase 3Results posted
• Trial to Assess Efficacy and Safety of Lacosamide in Subjects With Osteoarthritis of the KneeTerminatedNCT00485472Phase 2Results posted
• A Study Designed to Test the Effectiveness and Safety of Treating Patients With Lacosamide for Migraine ProphylaxisCompletedNCT00440518Phase 2Results posted
• Assessing Efficacy and Safety of Lacosamide Compared to Placebo in Reducing Signs and Symptoms of Fibromyalgia Syndrome.CompletedNCT00401830Phase 2Results posted
• A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic NeuropathyCompletedNCT00350103Phase 3Results posted
• An Open-label Continuation Trial to Assess the Continued Efficacy and Safety of Ascending Doses of Lacosamide in Subjects With Chronic Refractory Neuropathic PainCompletedNCT00237458Phase 2Results posted
• A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic NeuropathyCompletedNCT00235443Phase 2/3Results posted
• A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic NeuropathyCompletedNCT00220337Phase 3Results posted
• Lacosamide Versus Propranolol in MigraineCompletedNCT05851781Phase 3
• An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.Status unknownNCT05788159Phase 1
• The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine PatientsCompletedNCT05632133Phase 3
• STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic PancreatitisActive, not recruitingNCT05603702Phase 1
• Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on BreathingCompletedNCT05598905Phase 4
• Lacosamide in Neonatal Status EpilepticusStatus unknownNCT05291455Phase 3
• Evaluation of the Efficacy and Safety of Lacosamide in Pediatric Patients With EpilepsyStatus unknownNCT04144218Phase 4
• The Effect of Lacosamide in Peripheral Neuropathic PainTerminatedNCT03777956Phase 2
• A Study to Investigate the Bioequivalence of Lacosamide 200mg Administered as Intravenous Solution and Oral Tablet in Healthy Chinese Male SubjectsCompletedNCT03204474Phase 1
• Open-label Clinical Trial of Lacosamide in ALSCompletedNCT03186040Phase 1/2
• A Study to Demonstrate the Bioequivalence of Lacosamide Tablets and Dry Syrup in Healthy Male Japanese SubjectsCompletedNCT02972125Phase 1
• Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status EpilepticusWithdrawnNCT02726867Phase 3
• Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure ManagementTerminatedNCT02409433Phase 4
• Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3
• Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty:WithdrawnNCT02342977Phase 2
• Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese SubjectsCompletedNCT01986608Phase 1
• IV Lacosamide: The Safety of Intravenous LacosamideCompletedNCT01981447Phase 3
• Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber NeuropathyCompletedNCT01911975Phase 3
• Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Single Dose Lacosamide in Subjects With Renal Impairment Compared to Healthy SubjectsCompletedNCT01796938Phase 1
• Lacosamide IV and EEG/EKG (LIVE) StudyTerminatedNCT01724918Phase 2
• A Multicenter, Open-label Study to Determine the Effects of Lacosamide on Sleep in Healthy SubjectsCompletedNCT01530386Phase 1
• Crossover Study of Neuropsychological Effects of Lacosamide and Carbamazepine Immediate Release in Healthy SubjectsCompletedNCT01530022Phase 1
• To Evaluate the Pharmacokinetics and Safety/Tolerability of Lacosamide in 3 Dosages in Healthy Male Korean SubjectsCompletedNCT01450111Phase 1
• Effects of Lacosamide on Human Motor Cortex Excitability: a Transcranial Magnetic Stimulation StudyCompletedNCT01382017Not applicable
• Three-way-cross-over Study to Evaluate Safety and Pharmacokinetics of Lacosamide in Healthy Japanese and Chinese MalesCompletedNCT01375387Phase 1
• Cognitive and Behavioral Effects of LacosamideCompletedNCT01175954Phase 4
• A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic NeuropathyCompletedNCT00861445Phase 2
• A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).CompletedNCT00861068Phase 2
• An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic NeuropathyCompletedNCT00861042Phase 2
• The Safety of Intravenous LacosamideCompletedNCT00832884Phase 4
• A Trial to Assess the Efficacy and Safety of SPM 927 (Lacosamide) in Subjects With Painful Distal Diabetic NeuropathyCompletedNCT00238524Phase 3
• An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)CompletedNCT00238511Phase 2
• A Trial to Assess the Efficacy and Safety of SPM 927 in Subjects With Painful Distal Diabetic NeuropathyCompletedNCT00235469Phase 2/3
• A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Trial to Investigate the Efficacy and Safety of SPM 927 (200mg/Day and 400mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary GeneralizationCompletedNCT00220415Phase 3
• Safety and Tolerability of Intravenous SPM 927 as Replacement for Oral SPM 927 in Subjects With Partial SeizuresCompletedNCT00151879Phase 2/3
• SPM 927 (400mg/Day and 600mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary GeneralizationCompletedNCT00136019Phase 3
• Trial to Assess the Efficacy and Safety of SPM 927 (200, 400, and 600mg/Day) in Subjects With Painful Distal Diabetic NeuropathyCompletedNCT00135109Phase 3

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