Hypoglycemic Agents: all 3,927 studies that test it

Page 6 of 40. Open to participants first (294), then studies with results posted, then the rest; newest registration first within each.

• Topiramate Treatment of Alcohol Use Disorders in African AmericansTerminatedNCT03018704Phase 4Results posted
• Glargine U300 Hospital TrialCompletedNCT03013985Phase 4Results posted
• Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart DiseaseCompletedNCT03011775Phase 4Results posted
• Effects of Agonists of Glucagon Like Peptide - 1 Receptors (GLP-1R) on Arterial Stiffness, Endothelial Glycocalyx and Coronary Flow Reserve in Patients With Coronary Artery Disease and Patients With Diabetes MellitusCompletedNCT03010683Not applicableResults posted
• Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)CompletedNCT03001076Phase 3Results posted
• Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or PlaceboCompletedNCT02993406Phase 3Results posted
• Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular RiskCompletedNCT02991118Phase 3Results posted
• Intranasal Insulin for Improving Cognitive Function in Multiple SclerosisCompletedNCT02988401Phase 1/2Results posted
• Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin IntolerantCompletedNCT02988115Phase 3Results posted
• Genomic Outcomes of MetforminCompletedNCT02986659Phase 4Results posted
• RCT Metformin for Reduction of Gestational Diabetes Mellitus EffectsCompletedNCT02980276Phase 3Results posted
• Interaction of Bexagliflozin With Metformin, Glimepiride and SitagliptinCompletedNCT02956044Phase 1Results posted
• Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell CarcinomaCompletedNCT02949700Phase 1/2Results posted
• Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation TherapyTerminatedNCT02946996Phase 2Results posted
• A Study of LY900014 Formulation in Healthy ParticipantsCompletedNCT02942654Phase 1Results posted
• Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)TerminatedNCT02932475Phase 3Results posted
• Metformin as an Upstream Therapy in Atrial FibrillationTerminatedNCT02931253Phase 2Results posted
• Treatment of Diabetes in Patients With Systolic Heart FailureCompletedNCT02920918Phase 4Results posted
• Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart FailureCompletedNCT02917031Phase 4Results posted
• A 38 Week Trial Comparing Effect and Safety of Insulin Degludec/Insulin Aspart vs. Insulin Glargine Plus Insulin Aspart in Subjects With Type 2 Diabetes Treated With Basal Insulin With or Without Oral Antidiabetic Treatment in Need of Treatment IntensificationCompletedNCT02906917Phase 3Results posted
• Omarigliptin Add-on to Insulin in Japanese Participants With Type 2 Diabetes Mellitus (T2DM, MK-3102-039)CompletedNCT02906709Phase 4Results posted
• Feasibility Study of Metformin Therapy in ADPKDCompletedNCT02903511Phase 2Results posted
• Linagliptin Add-on to Insulin Background TherapyCompletedNCT02897349Phase 3Results posted
• A Study of the Effect of Abemaciclib on Metformin and Iohexol in Healthy ParticipantsCompletedNCT02884089Phase 1Results posted
• Topiramate for Cryptogenic Sensory Peripheral Neuropathy in Metabolic Syndrome (CSPN)CompletedNCT02878798Phase 2Results posted
• Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine CancerTerminatedNCT02874430Phase 2Results posted
• Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric InfarctionTerminatedNCT02864953Phase 3Results posted
• Phase 3 Alogliptin Pediatric StudyCompletedNCT02856113Phase 3Results posted
• Transporter Cocktail Mutual InteractionCompletedNCT02854527Phase 1Results posted
• Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?CompletedNCT02846233Not applicableResults posted
• Safety and Efficacy of Bexagliflozin in Type 2 Diabetes Mellitus Patients With Moderate Renal ImpairmentCompletedNCT02836873Phase 3Results posted
• Efficacy and Safety of Continuous Subcutaneous Insulin Infusion of Faster-acting Insulin Aspart Compared to NovoRapid® in Adults With Type 1 DiabetesCompletedNCT02825251Phase 3Results posted
• Study to Evaluate the Effects of a High-Fat Meal on Bexagliflozin in Healthy SubjectsCompletedNCT02820298Phase 1Results posted
• Empa/Lina FDC Food Effect Study (Japan)CompletedNCT02815644Phase 1Results posted
• DA-EPOCH-Rituximab/Metformin (RM) for Double Hit LymphomaTerminatedNCT02815397Phase 2Results posted
• Intranasal Insulin and Post-stroke Cognition: A Pilot StudyCompletedNCT02810392Phase 2Results posted
• MEtformin and Lorcaserin for WeighT Loss in SchizophreniaTerminatedNCT02796144Phase 4Results posted
• A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)CompletedNCT02791490Phase 3Results posted
• Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension PeriodCompletedNCT02787551Phase 3Results posted
• PPARγ Agonist Treatment for Cocaine DependenceCompletedNCT02774343Phase 1/2Results posted
• An Exploratory Study of the Effects of Trelagliptin and Alogliptin on Glucose Variability in Patients With Type 2 Diabetes MellitusCompletedNCT02771093Phase 4Results posted
• A Study of Treprostinil and a New Formulation of LY900014 in Healthy Japanese ParticipantsCompletedNCT02770521Phase 1Results posted
• Safety and Efficacy of Bexagliflozin Compared to Glimepiride as Add-on Therapy to Metformin in Type 2 Diabetes SubjectsCompletedNCT02769481Phase 3Results posted
• Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Subjects With Type 2 DiabetesCompletedNCT02762578Phase 3Results posted
• Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Linagliptin Compared With the Free Combination of Empagliflozin Tablet and Linagliptin Tablet in Healthy Male and Female SubjectsCompletedNCT02758171Phase 1Results posted
• A Study to Compare the Effects of a Test and Reference Formulation of LY900014 in Healthy ParticipantsCompletedNCT02752087Phase 1Results posted
• Sitagliptin in Non-Diabetic Patients Undergoing General SurgeryCompletedNCT02741687Phase 4Results posted
• Randomized Sitagliptin Withdrawal Study (MK-0431-845)CompletedNCT02738879Phase 3Results posted
• Efficacy and Safety of Toujeo® Versus Tresiba® in Insulin-Naive Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Antihyperglycemic Drug(s) ± GLP-1 Receptor AgonistCompletedNCT02738151Phase 4Results posted
• Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes MellitusCompletedNCT02735044Phase 3Results posted
• Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid LeukemiaTerminatedNCT02730195Phase 2Results posted
• An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed ConditionsCompletedNCT02722239Phase 1Results posted
• Safety and Efficacy of Bexagliflozin as Monotherapy in Patients With Type 2 DiabetesCompletedNCT02715258Phase 3Results posted
• A Pharmacokinetic Study Comparing VI-0521 With Placebo in Obese AdolescentsCompletedNCT02714062Phase 4Results posted
• Characterization of Epilepsy Patients BEEP 2bCompletedNCT02707965Phase 1Results posted
• A Study of LY900014 in Participants With Type 1 Diabetes on Insulin Injection TherapyCompletedNCT02703350Phase 1Results posted
• A Study of LY900014 in Participants With Type 2 Diabetes on Insulin Injection TherapyCompletedNCT02703337Phase 1Results posted
• A Study of LY900014 Formulation in Participants With Type 1 Diabetes Mellitus Using Insulin PumpsCompletedNCT02703324Phase 1Results posted
• Use of Low Dose Pioglitazone to Treat Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT02697617Phase 2Results posted
• A Study Comparing the Efficacy and Safety of the Morning Injection of Toujeo Versus Lantus in Patients With Type 1 Diabetes MellitusCompletedNCT02688933Phase 4Results posted
• Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMDCompletedNCT02684578Phase 2Results posted
• Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT02683525Phase 2Results posted
• DPP4 Inhibition & Beta Cell FunctionCompletedNCT02683187Phase 1Results posted
• Effect of Insulin Degludec Versus Insulin Glargine on Glycemic Variability in Patients With Type 2 Diabetes MellitusCompletedNCT02680457Phase 4Results posted
• Additional Insulin for Fat and Protein in Children With Diabetes StudyTerminatedNCT02680054Phase 4Results posted
• Efficacy and Safety of Faster-acting Insulin Aspart Compared to NovoRapid® Both in Combination With Insulin Degludec in Children and Adolescents With Type 1 DiabetesCompletedNCT02670915Phase 3Results posted
• Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)CompletedNCT02666664Phase 3Results posted
• Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT02656017Phase 2Results posted
• A Pilot Study to Assess the Safety of Oral Insulin in Patients With Nonalcolholic Steatohepatitis (NASH)CompletedNCT02653300Phase 2Results posted
• Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart Twice Daily and Biphasic Insulin Aspart Twice Daily in Subjects With Type 2 Diabetes Mellitus Before, During and After RamadanCompletedNCT02648217Phase 3Results posted
• 12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on MetforminCompletedNCT02647320Phase 2Results posted
• A Study of Various Formulations of LY900014 in Healthy ParticipantsCompletedNCT02636361Phase 1Results posted
• EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)CompletedNCT02635386Phase 3Results posted
• Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic SyndromeCompletedNCT02633488Not applicableResults posted
• Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)CompletedNCT02623998Phase 3Results posted
• Long-Term Safety Study of Canagliflozin (TA-7284) in Combination With Insulin in Patients With Type 2 Diabetes MellitusCompletedNCT02622113Phase 4Results posted
• Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer PatientsCompletedNCT02614859Phase 2Results posted
• Continuous Glucose Monitoring to Assess Glycemia in Chronic Kidney Disease - Changing Glucose ManagementCompletedNCT02608177Not applicableResults posted
• Metformin for the Prevention of Episodic Migraine (MPEM)CompletedNCT02593097Phase 3Results posted
• A Study of U-500 Insulin (LY041001) in Participants With Type 2 DiabetesTerminatedNCT02588950Phase 1Results posted
• Comparing Efficacy and Safety of Thrice Daily Versus Twice Daily NovoMix® 30 (Biphasic Insulin Aspart 30) in Subjects With Type 2 Diabetes Inadequately Controlled With Basal InsulinCompletedNCT02582242Phase 4Results posted
• Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant LesionActive, not recruitingNCT02581137Phase 2Results posted
• Demonstrate Bioequivalence of Two 12.5 mg Empagliflozin/500 mg Metformin Fixed Dose Combination Tablets With Free Combination of Empagliflozin 25 mg and Metformin 1000 mg in Healthy Male and Female Volunteers Under Fed ConditionsCompletedNCT02577315Phase 1Results posted
• Double-blind Sitagliptin Add-on Study in Japanese Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Ipragliflozin (MK-0431J-842)CompletedNCT02577016Phase 3Results posted
• DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)CompletedNCT02574845Phase 1Results posted
• Metformin for Preventing Frailty in High-risk Older AdultsCompletedNCT02570672Phase 2Results posted
• Ipragliflozin Add-on Long-term Study in Japanese Participants With Type 2 Diabetes Mellitus on Sitagliptin (MK-0431J-849)CompletedNCT02564211Phase 3Results posted
• A Novel Positron Emission Tomography (PET) Approach to Measuring Myocardial MetabolismCompletedNCT02563834Not applicableResults posted
• Validation of Macimorelin as a Test for Adult Growth Hormone DeficiencyCompletedNCT02558829Phase 3Results posted
• Bexagliflozin Efficacy and Safety TrialCompletedNCT02558296Phase 3Results posted
• Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac SurgeryCompletedNCT02556918Phase 4Results posted
• Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide MetforminCompletedNCT02552355Phase 2Results posted
• A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on MetforminCompletedNCT02551874Phase 3Results posted
• Sitagliptin Therapy and Kinetics of Inflammatory MarkersCompletedNCT02536248Phase 3Results posted
• A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)CompletedNCT02532855Phase 3Results posted
• Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL)TerminatedNCT02531308Phase 2Results posted
• Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DMCompletedNCT02526524Phase 2Results posted
• A Study of a New LY900014 Formulation in Healthy ParticipantsCompletedNCT02525744Phase 1Results posted
• Spinal Cord Injury Neuroprotection With GlyburideTerminatedNCT02524379Phase 1/2Results posted
• Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAsCompletedNCT02515773Phase 4Results posted

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