Histone Deacetylase Inhibitors: all 1,242 studies that test it
Page 11 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.
- Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid LeukemiaCompletedNCT00867672Phase 2
- Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous SystemCompletedNCT00867178Phase 1
- A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential ThrombocythaemiaStatus unknownNCT00866762Phase 2
- Bioequivalence Study of Divalproex Sodium 125 MG Delayed Release Tablets Under Fasting ConditionsCompletedNCT00864006Phase 1
- Study of Vorinostat Plus Melphalan and Prednisone (Zmp) in Advanced, Refractory Multiple Myeloma PatientsTerminatedNCT00857324Phase 1/2
- Study of LBH589 (Panobinostat) to Treat Malignant Brain TumorsTerminatedNCT00848523Phase 2
- Panobinostat in Combination With Idarubicin and Cytarabine in Patients Aged 65 Years or Older With Newly Diagnosed Acute Myeloblastic Leukaemia (AML)CompletedNCT00840346Phase 1/2
- Relapsed and/or Refractory Non-Hodgkin Lymphoma StudyWithdrawnNCT00837174Phase 2
- Sorafenib and LBH589 in Hepatocellular Carcinoma (HCC)TerminatedNCT00823290Phase 1
- Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid MalignanciesCompletedNCT00820508Phase 1
- Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic LeukemiaCompletedNCT00816283Phase 1
- Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)Status unknownNCT00810680Not applicable
- Vorinostat in Combination With Vinorelbine in Patients With Advanced CancerTerminatedNCT00801151Phase 1
- Therapeutic Induction of Endogenous AntibioticsCompletedNCT00800930Phase 2
- Phase II Study of Histone-deacetylase Inhibitor ITF2357 in Refractory/Relapsed Lymphocytic LeukemiaTerminatedNCT00792831Phase 2
- Phase II Clinical Trial of ITF2357 In Patients With Relapsed/Refractory Multiple MyelomaTerminatedNCT00792506Phase 2
- A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast CancerCompletedNCT00788931Phase 1
- Vorinostat in Treating Women With Ductal Carcinoma in Situ of the BreastCompletedNCT00788112Phase 1
- Vorinostat and Low Dose Cytarabine for High Risk MyelodysplasiaCompletedNCT00776503Phase 1/2
- A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian CancerStatus unknownNCT00772798Phase 2
- A Phase I Trial of Vorinostat in Combination With Bevacizumab & Irinotecan in Recurrent GlioblastomaCompletedNCT00762255Phase 1
- A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and EtoposideCompletedNCT00759824Phase 2
- A Phase I, Multicenter, Open Label Study on the Effects of SNDX-275 on Expression of Biomarkers in Subjects With Newly Diagnosed Breast CancerTerminatedNCT00754312Phase 1
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MK0683 in Patients With Advanced Cancer (0683-008)CompletedNCT00750178Phase 1
- Vorinostat, Bortezomib, and Doxorubicin Hydrochloride Liposome in Treating Patients With Relapsed or Refractory Multiple MyelomaTerminatedNCT00744354Phase 1
- Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid TumorsCompletedNCT00739414Phase 1
- Phase I Study of LBH589 & Erlotinib for Advanced Aerodigestive Tract CancersCompletedNCT00738751Phase 1
- Phase I Study of Induction Therapy With VELCADE and Vorinostat in Patients With Surgically Resectable Non-Small Cell Lung CancerCompletedNCT00731952Phase 1
- Vorinostat and Lenalidomide After Autologous Stem Cell Transplant in Treating Patients With Multiple MyelomaCompletedNCT00729118Phase 1
- A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of CUDC-101 in Patients With Advanced Solid TumorsCompletedNCT00728793Phase 1
- The Effects of Butyrate Enemas on Visceral PerceptionCompletedNCT00726817Not applicable
- HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast CancerCompletedNCT00719875Phase 1
- Comparing The Effect On Cognition Of Adjunctive Therapy With Zonisamide Versus Sodium ValproateCompletedNCT00713622Phase 4
- Carboplatin, Paclitaxel, Bevacizumab and Vorinostat for Patients With Advanced Non-Small Cell Lung CancerTerminatedNCT00702572Phase 1
- Study of Oral LBH589 in Patients With Cutaneous T-cell Lymphoma and Adult T-cell Leukemia/LymphomaTerminatedNCT00699296Phase 2
- Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid TumoursCompletedNCT00697879Phase 1
- Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLCTerminatedNCT00697476Phase 1/2
- Phase II Trial of LBH589 in Refractory Colorectal CancerCompletedNCT00690677Phase 2
- Panobinostat (LBH589) and Imatinib Mesylate in Treating Patients With Previously Treated Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT00686218Phase 1
- Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM)CompletedNCT00681980Phase 3
- A Safety and Dose-finding Study of JNJ-26481585 for Patients With Advanced Solid Malignancies and Lymphoma.CompletedNCT00677105Phase 1
- A Research Study to Evaluate the Safety of R306465, a Drug in Development for Cancer and to Study the Absorption, Break Down and Elimination in Patients With Advanced Solid Malignancies.CompletedNCT00677001Phase 1
- A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic SyndromeTerminatedNCT00676728Phase 1
- A Phase I Study of LBH589 (Panobinostat) in Combination With External Beam Radiotherapy for the Treatment of Prostate Cancer, Esophageal Cancer and Head and Neck CancerCompletedNCT00670553Phase 1
- Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)TerminatedNCT00666497Phase 2
- A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate CancerCompletedNCT00663832Phase 1
- Food Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mgCompletedNCT00648076Phase 1
- Fasting Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mgCompletedNCT00647712Phase 1
- Pediatric Switch Study for Children and Adolescent Patients With EpilepsyCompletedNCT00646711Phase 2
- Phase I Study of Vorinostat and Sorafenib in Advanced CancerCompletedNCT00635791Phase 1
- Phase II Study of Valproate and Doxorubicin in Malignant MesotheliomaCompletedNCT00634205Phase 2
- A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid TumorsCompletedNCT00570284Phase 1
- The Effect of Valproate on Benzodiazepine Withdrawal SeverityCompletedNCT00570219Not applicable
- Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and Relapsed Solid Malignancies.TerminatedNCT00565227Phase 1
- Effectiveness of Lithium and Valproate in Treating High-Risk Bipolar DisorderCompletedNCT00563992Phase 1
- Study of the Safety and Tolerability of Oral Capsule Form of PCI-24781 in Advanced Cancer PatientsCompletedNCT00562224Phase 1
- LBH589, Paclitaxel, Carboplatin +/- Bevacizumab for Solid TumorsCompletedNCT00556088Phase 1
- Effects of Atypical Antipsychotic and Valproate Combination Therapy on Glucose and Lipid Metabolism in SchizophreniaCompletedNCT00552500Not applicable
- LBH589 and Gemcitabine in the Treatment of Solid TumorsTerminatedNCT00550199Phase 1
- Abilify in Bipolar Disorder for 6 Weeks Treatment EffectivenessCompletedNCT00545142Phase 4
- MGCD0103 Administered in Combination With Azacitidine (Vidaza®) to Subjects With Relapsed or Refractory Hodgkin or Non-Hodgkin LymphomaTerminatedNCT00543582Phase 2
- Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal CancerCompletedNCT00537121Phase 1
- Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural MesotheliomaCompletedNCT00535951Phase 1
- Mechanism of Fatty Acid-induced Impairment of Glucose-simulated Insulin Secretion - Effect of BuphenylCompletedNCT00533559Phase 4
- Hydralazine Valproate for Ovarian CancerStatus unknownNCT00533299Phase 3
- Hydralazine Valproate for Cervical CancerStatus unknownNCT00532818Phase 3
- Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.CompletedNCT00532675Phase 1
- Safety Study of LBH589 When Given in Combination With Bortezomib in Adult Patients With Multiple MyelomaCompletedNCT00532389Phase 1
- Valproic Acid and Bevacizumab in Patients With Advanced CancerCompletedNCT00530907Phase 1
- Azacitidine and Valproic Acid Plus Carboplatin in Patients With Ovarian CancerCompletedNCT00529022Phase 1
- HDAC Inhibitor Valproic Acid as an Effective Therapy for Chronic Lymphocytic LeukemiaTerminatedNCT00524667Phase 2
- Safety and Efficiency Study of Valproic Acid In HAM/TSPTerminatedNCT00519181Not applicable
- Valproate and Etoposide for Patients With Neuronal Tumors and Brain MetastasesCompletedNCT00513162Phase 1
- Study to Evaluate Combination Treatment of MGCD0103 and Docetaxel (Taxotere®) for Subjects With Advanced Cancer TumorsTerminatedNCT00511576Phase 1
- SB939 in Treating Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT00504296Phase 1
- A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid TumorsCompletedNCT00503451Phase 1
- Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver DysfunctionCompletedNCT00499811Phase 1
- Azacytidine and Valproic Acid in Patients With Advanced CancersCompletedNCT00496444Phase 1
- phII Study of an HDAC Inhibitor in Very High-risk Relapsed/Refractory Hodgkin's Lymphoma PatientsTerminatedNCT00496431Phase 1/2
- Safety of LBH589 Alone and in Combination With IV Docetaxel and PrednisoneTerminatedNCT00493766Phase 1
- Valproic Acid in Ambulant Adults With Spinal Muscular AtrophyCompletedNCT00481013Phase 2
- Study of the Tolerability, Safety, and Pharmacokinetics of CRA-024781 in Cancer PatientsCompletedNCT00473577Phase 1
- A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589CompletedNCT00472368Phase 1
- Vorinostat and Palliative RadiotherapyCompletedNCT00455351Phase 1
- The Efficacy and Safety of ITF2357 in AISStatus unknownNCT00442182Phase 2
- Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain MetastasesTerminatedNCT00437957Phase 1
- A Phase II Study of MGCD0103 (MG-0103) in Patients With Refractory Chronic Lymphocytic LeukemiaCompletedNCT00431873Phase 2
- Valproic Acid Sodium Salt in Bipolar DisorderCompletedNCT00431522Phase 4
- A Phase II Study of Belinostat in Combination With Bortezomib in Patients With Relapsed, Refractory Multiple MyelomaTerminatedNCT00431340Phase 2
- Safety of LBH589 Alone and in Combination With Intravenous Docetaxel and PrednisoneTerminatedNCT00419536Phase 1
- Clinical Trial of SAHA in Patients With Breast CancerStatus unknownNCT00416130Phase 1/2
- Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid TumorsCompletedNCT00413322Phase 1
- Study of Oral PXD101 in Patients With Advanced Solid Tumors or LymphomaCompletedNCT00413075Phase 1
- LBH589 in Adult Patients With Advanced Solid Tumors or Cutaneous T-cell LymphomaCompletedNCT00412997Phase 1
- A Phase II Study of Epigenetic Therapy to Overcome Chemotherapy Resistance in Refractory Solid TumorsCompletedNCT00404508Phase 2
- Hydralazine and Valproate Plus Cisplatin Chemoradiation in Cervical CancerCompletedNCT00404326Phase 2
- Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid LeukemiaActive, not recruitingNCT00392353Phase 1/2
- Phenylbutyrate and Valganciclovir in Treating Patients With Relapsed or Refractory Epstein-Barr Virus-Positive CancerWithdrawnNCT00387530Phase 2
- Trial of Valproic Acid in Patients With Progressive Supranuclear Palsy (Depakine)CompletedNCT00385710Phase 2
- Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia PatientsWithdrawnNCT00375557Phase 4