Histone Deacetylase Inhibitors: all 1,242 studies that test it
Page 12 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.
- MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory DiseaseTerminatedNCT00374296Phase 2
- Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular AtrophyCompletedNCT00374075Phase 1
- A Phase I/II Study of MGCD0103 (MG-0103) in Combination With GemcitabineCompletedNCT00372437Phase 1/2
- Study of MGCD0103 Given Three Times Weekly in Patients With Relapsed and Refractory LymphomaCompletedNCT00359086Phase 2
- Study of MGCD0103 (MG-0103) in Patients With Relapsed or Refractory Hodgkin's LymphomaTerminatedNCT00358982Phase 2
- Phase I/II Trial of Valproic Acid and Karenitecin for MelanomaTerminatedNCT00358319Phase 1/2
- Vorinostat and Decitabine in Treating Patients With Relapsed, Refractory, or Poor-Prognosis Hematologic Cancer or Other DiseasesCompletedNCT00357708Phase 1
- Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative DisordersCompletedNCT00357305Phase 1
- PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic or Unresectable Solid Tumors or LymphomaTerminatedNCT00354185Phase 1
- Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other DiseasesCompletedNCT00351975Phase 1
- PXD101 and Bortezomib in Treating Patients With Advanced Solid Tumors or LymphomasCompletedNCT00348985Phase 1
- Comparison of Immediate vs Gradual Switch to Divalproex in Adults With Intellectual DisabilityCompletedNCT00347152Not applicable
- Vorinostat and IV Fluorouracil/Leucovorin (5FU/LV) in Patients With Metastatic Colorectal CancerCompletedNCT00336141Phase 1
- Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell LymphomaActive, not recruitingNCT00336063Phase 1
- Belinostat and Isotretinoin in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by SurgeryCompletedNCT00334789Phase 1
- A Comparison Study of the Efficacy and Tolerability of Depakote ER and Depakote DRCompletedNCT00334347Phase 4
- Vorinostat and Doxorubicin in Treating Patients With Metastatic or Locally Advanced Solid TumorsCompletedNCT00331955Phase 1
- Vorinostat and Idarubicin in Treating Patients With Relapsed or Refractory Leukemia or Myelodysplastic SyndromesCompletedNCT00331513Phase 1
- Vorinostat and Alvocidib in Treating Patients With Advanced Solid TumorsCompletedNCT00324480Phase 1
- A Phase I/II Study of MGCD0103 With Azacitidine in Patients With High-Risk Myelodysplastic Syndrome (MDS) or Acute Myelogenous LeukemiaCompletedNCT00324220Phase 1/2
- A Phase I Study of MGCD0103 Given Twice Weekly in Patients With Leukemia or Myelodysplastic SyndromesCompletedNCT00324194Phase 1
- A Phase I Study of MGCD0103 Given Three-Times Weekly In Patients With Leukemia Or Myelodysplastic SyndromesCompletedNCT00324129Phase 1
- Study of MGCD0103 Given Three-Times Weekly in Patients With Advanced Solid Tumors or Non-Hodgkin's LymphomaCompletedNCT00323934Phase 1
- Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With DementiaTerminatedNCT00315900Phase 3
- Study of Valproic Acid to Treat HIV Infected AdultsTerminatedNCT00312546Phase 1
- Vorinostat and Bortezomib in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT00310024Phase 1
- Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and HostilityCompletedNCT00308360Phase 4
- A Pharmacokinetic Study to Compare the Dosing of Valproic Acid in Subjects With Different Body WeightsTerminatedNCT00298857Phase 4
- Valproic Acid and Its Effects on HIV Latent ReservoirsCompletedNCT00289952Phase 2
- Vorinostat, Paclitaxel, and Carboplatin in Treating Patients With Advanced or Refractory Solid TumorsCompletedNCT00287937Phase 1
- Study of Divalproex Extended Release Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomania or Mild ManiaCompletedNCT00278772Phase 3
- Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory AnemiaCompletedNCT00278330Phase 1
- Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous LeukemiaCompletedNCT00275080Phase 1
- Safety Study of Sodium Divalproate in Bipolar Disorder in AdolescentsCompletedNCT00271258Phase 3
- Vorinostat and Temozolomide in Treating Patients With Malignant GliomasActive, not recruitingNCT00268385Phase 1
- VALID : VAlproate Versus LIthium in Bipolar DisordersCompletedNCT00264173Phase 4
- Phase I Trial of Valproic Acid and Epirubicin in Solid Tumor MalignanciesCompletedNCT00246103Phase 1
- Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00243100Phase 1
- A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With EpilepsyCompletedNCT00236717Phase 3
- Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity DisorderCompletedNCT00228046Phase 4
- Vorinostat and Bortezomib in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00227513Phase 1
- Depakote-ER for Depressive and Bipolar DepressionCompletedNCT00226343Phase 4
- Depakote ER in Borderline Personality DisorderCompletedNCT00222482Not applicable
- Efficacy of Valproate in Peripheral Neuropathic PainTerminatedNCT00221637Phase 2/3
- Lithium Versus Divalproex for Treating Pediatric Bipolar DisorderCompletedNCT00221429Phase 3
- Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and AdultsCompletedNCT00218114Phase 3
- Effectiveness of Divalproex Sodium (Depakote) in Treating Children With Temper Outbursts and Severe Mood SwingsCompletedNCT00217932Phase 2
- Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD)CompletedNCT00212316Phase 2
- Divalproex Sodium ER in Adult AutismCompletedNCT00211796Phase 4
- Comparing Compliance, Tolerability, Efficacy and Adverse Events in Bipolar Tients From Valproic Acid to Depakote ERCompletedNCT00211250Phase 4
- A Comparison of Two Standard Therapies in the Management of Dementia With AgitationCompletedNCT00208819Phase 4
- Depakote ER Therapy for Mania Comorbid With Substance AbuseCompletedNCT00208195Phase 4
- Six Month Trial of Lamotrigine vs. Sodium Valproate for Treatment of Mixed ManiaCompletedNCT00206778Phase 2
- Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or DependenceWithdrawnNCT00204503Phase 2
- Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use DisorderCompletedNCT00203528Phase 4
- Maintenance Phase Treatment With Divalproex for Post Traumatic Stress DisorderTerminatedNCT00203385Phase 4
- Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety SymptomsCompletedNCT00202514Phase 2/3
- Safety And Efficacy Study Of Depakote ER To Treat Pediatric Bipolar DisorderCompletedNCT00199966Phase 4
- Study of Depakote for Behavioral and Psychological Symptoms in DementiaStatus unknownNCT00197834Phase 1
- Study Designed to Evaluate the Safety of Prophylactic Depakote ER in the Treatment of Adolescents With MigraineCompletedNCT00195806Phase 3
- A Study for the Treatment of Mania Associated With Bipolar I Disorder in Children and AdolescentsCompletedNCT00195780Phase 3
- Evaluate the Safety of Depakote Extended Release Tablets in the Treatment of Mania Associated With Bipolar Disorder in Children and AdolescentsCompletedNCT00195767Phase 3
- A Phase III Open-Label, Multi-Center, Long-Term Extension Study of Depakote ER in Subjects Who Either Completed or Prematurely Discontinued Due to Ineffectiveness From Study M02-488.CompletedNCT00195754Phase 3
- The Safety and Efficacy of Divalproex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Study in AdolescentsCompletedNCT00195741Phase 3
- Treatment With ATRA-IV and Depakote in Patients With Advanced Solid Tumor MalignanciesTerminatedNCT00195156Phase 1
- Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic MelanomaCompletedNCT00185302Phase 2
- Study of Depakote ER for the Treatment of Mania in Children Ages 6-12 With Bipolar DisorderCompletedNCT00181727Phase 4
- Valproic Acid in the Induction of EBV Lytic Cycle Antigen Expression in Nasopharyngeal CarcinomaWithdrawnNCT00181220Phase 1
- Differentiation Induction in Acute Myelogenous LeukemiaCompletedNCT00175812Phase 1/2
- Study of Efficacy of Sodium Valproate in Therapy of Bronchial AsthmaCompletedNCT00153270Phase 4
- Seroquel in Acute Mania: Study to Investigate if Valproate Add-On Therapy is Superior to Quetiapine Monotherapy in Acutely Manic PatientsTerminatedNCT00139074Phase 4
- Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid TumorsCompletedNCT00138177Phase 1
- Hormone Profiles in Adults With Newly Diagnosed EpilepsyStatus unknownNCT00137709Phase 4
- Trial of Sodium Valproate in Amyotrophic Lateral SclerosisCompletedNCT00136110Phase 3
- Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity CancerCompletedNCT00132067Phase 2
- Clinical Trial of PXD101 in Patients With Advanced Multiple MyelomaCompletedNCT00131261Phase 2
- A Study of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Malignant Lymphoma (0683-030)CompletedNCT00127140Phase 1
- A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)TerminatedNCT00126451Phase 2
- Vorinostat and Capecitabine in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00121277Phase 1
- Efficacy and Safety of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Alcohol Dependency in Patients With Bipolar DisorderCompletedNCT00114686Phase 3
- Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's LymphomaCompletedNCT00109824Phase 1
- A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Advanced Multiple Myeloma (0683-004)TerminatedNCT00109109Phase 1
- Divalproex Sodium in the Treatment of PTSD (Post-Traumatic Stress Disorder)CompletedNCT00108576Phase 3
- Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis)CompletedNCT00107770Phase 1/2
- Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS TumorsCompletedNCT00107458Phase 1
- A Research Study for Patients With Metastatic Renal Cell CarcinomaCompletedNCT00106613Phase 2
- A Research Study for Patients With Prostate CancerCompletedNCT00106418Phase 2
- Continuation Trial Evaluating the Tolerability and Activity of FK228 in Patients That Completed Prior Study With FK228CompletedNCT00106301Phase 2
- A Study for Treatment of Partial Seizures in ChildrenCompletedNCT00102713Phase 3
- MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid LeukemiaCompletedNCT00101179Phase 1
- FR901228 in Treating Patients With Refractory Stomach Cancer or Gastroesophageal Junction CancerTerminatedNCT00098527Phase 2
- FR901228 in Treating Patients With Metastatic Breast CancerCompletedNCT00098397Phase 2
- An Investigational Drug Study With Suberoylanilide Hydroxamic Acid in Relapsed Diffuse Large B-cell Lymphoma (0683-013)CompletedNCT00097929Phase 2
- Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's DiseaseCompletedNCT00095355Phase 2
- Olanzapine vs. Comparator and Placebo in the Treatment of Patients With Bipolar I DisorderCompletedNCT00094549Phase 4
- Oral SAHA (Suberoylanilide Hydroxamic Acid) in Advanced Cutaneous T-cell Lymphoma (0683-001)CompletedNCT00091559Phase 2
- Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or Peritoneal Cavity CancerTerminatedNCT00091195Phase 2
- Effect of Lithium and Divalproex in Alzheimer's DiseaseCompletedNCT00088387Phase 2
- Romidepsin in Treating Patients With Relapsed Small Cell Lung CancerCompletedNCT00086827Phase 2
- Decitabine and Valproic Acid in Treating Patients With Non-Small Cell Lung CancerCompletedNCT00084981Phase 1