Histamine Antagonists: all 646 studies that test it
Page 1 of 7. Open to participants first (64), then studies with results posted, then the rest; newest registration first within each.
- A Single and Multiple Ascending Dose Study of EPX-100 in Healthy Adult ParticipantsRecruitingNCT07879170Phase 1
- Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/GlioblastomaNot yet recruitingNCT07859059Phase 1/2
- DV Plus Toripalimab With Cetirizine and Mecobalamin Pretreatment in Patients With Locally Advanced Unresectable or Metastatic Bladder CancerNot yet recruitingNCT07853053Phase 1
- Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular CancerNot yet recruitingNCT07836712Phase 2
- A Study to Evaluate the Preliminary Efficacy and Safety of Terfenadine in Patients With Relapsing-Remitting Multiple SclerosisRecruitingNCT07827716Phase 2
- Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With EndometriosisNot yet recruitingNCT07821320Phase 2
- Ebastine for Adjuvant Treatment of Tumor Budding-Positive Liver Cancer After SurgeryNot yet recruitingNCT07734766Phase 4
- Neonatal White Matter Injury Trial (WRAP)RecruitingNCT07688746Phase 1
- Optimizing Ancillary Therapies With Immune Checkpoint Inhibitors for Solid Tumors (OAT ICI)RecruitingNCT07661459Phase 2
- Desloratadine as Adjunct Therapy for Rheumatoid ArthritisRecruitingNCT07632872Phase 2
- Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid ArthritisRecruitingNCT07566351Phase 2
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingNCT07542756Phase 4
- Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester AbortionsRecruitingNCT07542730Phase 4
- Antihistamine for Prevention of HTR After Blood Primed CPBRecruitingNCT07536152Phase 4
- Comparison of Antihistamine and Antileukotriene Add-On Therapy to Intranasal Corticosteroid in Allergic RhinitisNot yet recruitingNCT07532993Phase 4
- Mast Cell Treatment in Post-tick Bite Illness (PTBI)Not yet recruitingNCT07526558Phase 2
- Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot ProjectNot yet recruitingNCT07472413Phase 3
- The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial InfarctionRecruitingNCT07381803Phase 3
- Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung CancerNot yet recruitingNCT07358689Phase 2
- Desloratadine in Patients With Ulcerative ColitisRecruitingNCT07333716Phase 2
- Histamines and Central HemodynamicsRecruitingNCT07285031Not applicable
- Topical Ketotifen 0.25% for Secondary VestibulodyniaRecruitingNCT07257029Phase 2
- Comparing Standard-Dose and High-Dose Cetirizine for Acute UrticariaRecruitingNCT07236372Not applicable
- Effect of Ebastine in Patients With Diarrhea Predominant Irritable Bowel SyndromeRecruitingNCT07114055Phase 2/3
- Rupatadine in Patients With Ulcerative ColitisRecruitingNCT07064707Phase 2
- Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration RepairsRecruitingNCT06910241Phase 3
- Phase III Clinical Study of Cetirizine Hydrochloride Injection in Treatment of Acute UrticariaRecruitingNCT06819774Phase 3
- Treatment Options for Chronic UrticariaNot yet recruitingNCT06816784Phase 2
- Fexofenadine as Adjuvant Therapy in Parkinson DiseaseRecruitingNCT06785298Phase 2/3
- Pharmacokinetics and Safety of Rupatadine in Participants With Renal Impairment Compared to Control ParticipantsRecruitingNCT06708520Phase 1
- Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung CancerNot yet recruitingNCT06704620Phase 3
- Anticholinergics for Cervical Edema in LaborRecruitingNCT06702670Phase 2/3
- A Trial of Camrelizumab Plus Nab-paclitaxel and Levocetirizine in Metastatic or Recurrent TNBCNot yet recruitingNCT06632405Phase 2
- Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life DepressionRecruitingNCT06591091Phase 2
- Effect and Safety of Fexofenadine Hydrochloride vs Placebo in Patients With Acute Myocardial Infaction: A Randomized Clinical TrialRecruitingNCT06548204Phase 2
- Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate CancerRecruitingNCT06480110Phase 1/2
- A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.Not yet recruitingNCT06396013Phase 1
- Diphenhydramine in Catheter Related Bladder DiscomfortEnrolling by invitationNCT06345261Not applicable
- Combining Clemastine and Aerobic Exercise to Treat Cognitive Dysfunction in Schizophrenia by Targeting Myelin PlasticityNot yet recruitingNCT06315972Phase 2
- Over-the-Counter Antihistamines & Heat StressRecruitingNCT06217367Phase 4
- The Role of Histamine in Muscle Protein Synthesis Following Resistance TrainingRecruitingNCT06152497Not applicable
- Organ Protective Effect of Cetirizine In Patients With Severe BurnsRecruitingNCT06126991Phase 1/2
- Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair TherapyNot yet recruitingNCT06065670Phase 1/2
- A Pilot Clinical Evaluation of Astepro® Nasal Spray for Management of Early SARS-CoV-2 InfectionRecruitingNCT06008860Phase 4
- IKS014 in Advanced Solid Tumors That Express HER2RecruitingNCT05872295Phase 1
- FS-1502 Versus T-DM1 for HER2-Positive Unresectable Locally Advanced or Metastatic Breast CancerRecruitingNCT05755048Phase 3
- Efficacy of Hydroxyzine for Patients With Panic DisorderNot yet recruitingNCT05737511Phase 4
- Antazoline in Comparison to Propafenone in Pharmacological Cardioversion of Atrial Fibrillation.RecruitingNCT05720572Phase 4
- Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic RhinitisRecruitingNCT05626621Phase 4
- The Possible Protective Role of Ketotifen Against Oxaliplatin Induced Peripheral NeuropathyRecruitingNCT05624138Phase 3
- Trial of Diphenhydramine for Sleep in Children With AutismRecruitingNCT05501678Phase 2
- Serotonin Receptor Blockers in Ischemic Mitral RegurgitationRecruitingNCT05469165Phase 2
- Loratadine for the Prevention of G-CSF-related Bone PainRecruitingNCT05421416Phase 2
- Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair TherapyRecruitingNCT05359653Phase 1/2
- Comparison of the Effects for Lightening the Shiners Among Different Treatments for RhinitisRecruitingNCT05348148Not applicable
- A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)RecruitingNCT05319730Phase 1/2
- Fexofenadine in Patients With Active Rheumatoid ArthritisRecruitingNCT05264025Phase 1/2
- An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut SyndromeRecruitingNCT05066217Phase 3
- A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet SyndromeRecruitingNCT04462770Phase 3
- Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
- Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell MobilizationRecruitingNCT04211259Early Phase 1
- Effect of Some Drugs on Rheumatoid Arithritis ActivityRecruitingNCT03770923Phase 3
- Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)RecruitingNCT02521311Phase 2
- Ketotifen for Children With Functional Dyspepsia in Association With Duodenal EosinophiliaRecruitingNCT02484248Phase 3
- Pediatric Oncology Nutrition Intervention TrialCompletedNCT06175273Phase 2/3Results posted
- Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility TrialTerminatedNCT05946551Phase 3Results posted
- A Placebo-controlled Study of 2-day Pre-treatment With Fexofenadine in Seasonal Allergic RhinitisCompletedNCT05692154Phase 3Results posted
- Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic ConjunctivitisCompletedNCT05591755Phase 3Results posted
- Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic ModelingTerminatedNCT05219604Phase 4Results posted
- The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained SwimmersTerminatedNCT05095311Phase 4Results posted
- Effect of Antihistamines on Ureteral Stent-Related SymptomsCompletedNCT04726345Phase 2Results posted
- Clinical Study for the Evaluation of Safety and Tolerability of PRO-172 Ophthalmic Solution+CompletedNCT04693429Phase 1Results posted
- Antihistamines in Eosinophilic EsophagitisTerminatedNCT04248712Phase 2Results posted
- Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V DiphenhydramineCompletedNCT04189588Phase 2Results posted
- Personalized Treatment Algorithms for Difficult-to-treat AsthmaCompletedNCT04179461Phase 2Results posted
- Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to OcrelizumabCompletedNCT04175834Phase 3Results posted
- A Study to Evaluate Cooling Sensation of an Allergy Product in Adults With a History of AllergiesCompletedNCT04162795Phase 4Results posted
- Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 YearsCompletedNCT04068948Phase 4Results posted
- Total Joint Arthroplasty and SleepCompletedNCT03968939Phase 4Results posted
- Loratadine for Improvement of Bone Pain in Patients With Chronic Granulocyte-Colony Stimulating Factor (G-CSF) UseTerminatedNCT03883386Phase 2Results posted
- Safety and Efficacy of Mometasone Furoate Nasal Spray With the Addition of Loratadine Versus Placebo in Participants With Seasonal Allergic Rhinitis (C94-145)CompletedNCT03855228Phase 3Results posted
- A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and VehicleCompletedNCT03489941Phase 3Results posted
- A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model.CompletedNCT03479307Phase 3Results posted
- Fexofenadine Use in Gastroesophageal Reflux SymptomsTerminatedNCT03425097Phase 2Results posted
- Clinical Evaluation of Etafilcon A With KetotifenCompletedNCT03388138Phase 2Results posted
- A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedNCT03368664Phase 3Results posted
- A Single-Center, Phase 2 Study Evaluating Bilastine Ophthalmic Solution in the CAC® ModelCompletedNCT03231969Phase 2Results posted
- Effect of an H1 Receptor Antagonist on Exercise Performance in HypoxiaCompletedNCT03192488Phase 4Results posted
- Safety and Efficacy of Isatuximab in Lymphoblastic LeukemiaTerminatedNCT02999633Phase 2Results posted
- Clinical Trial Comparing JDP-205 to Diphenhydramine Injection for the Treatment of Acute UrticariaCompletedNCT02935699Phase 3Results posted
- Neuromyelitis Optica (NMO) & CetirizineCompletedNCT02865018Phase 1/2Results posted
- Efficacy of Co-administration of Bilastine and Montelukast in Patients With SARC and AsthmaCompletedNCT02761252Phase 4Results posted
- A Multi-Center, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety of AC-170 Ophthalmic SolutionCompletedNCT02756624Phase 3Results posted
- Treg Therapy in Subclinical Inflammation in Kidney TransplantationCompletedNCT02711826Phase 1/2Results posted
- A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and ComorbidityCompletedNCT02655354Not applicableResults posted
- Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
- Evaluation of Diphenhydramine Hydrochloride Effects in Subjects With Occasional SleeplessnessCompletedNCT02578186Phase 4Results posted
- Effects of Bilastine on F1 Simulator Driving Performance in Patients Affected by Allergic Rhinitis and/or UrticariaCompletedNCT02576041Phase 4Results posted
- Effects of Cyproheptadine on Growth and Behavior in Pediatric Feeding DisordersTerminatedNCT02568007Phase 4Results posted
- Comparability and Standardization of Controlled Allergen Challenge FacilitiesCompletedNCT02543346Phase 4Results posted