Ganaxolone: all 24 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Clinical Trial Evaluating the Effects of Ganaxolone in Children With AutismNot yet recruitingNCT07635862Phase 2
• Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years OldNot yet recruitingNCT05249556Phase 3
• Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related EpilepsyTerminatedNCT05604170Phase 3Results posted
• Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related EpilepsyCompletedNCT05323734Phase 3Results posted
• Randomized Therapy In Status EpilepticusCompletedNCT04391569Phase 3Results posted
• Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B)CompletedNCT04285346Phase 2Results posted
• Study of Adjunctive Ganaxolone Treatment in Female Children With Protocadherin 19 (PCDH19)-Related Epilepsy (Violet Study)CompletedNCT03865732Phase 2Results posted
• Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency DisorderCompletedNCT03572933Phase 3Results posted
• A Clinical Trial of Oral Ganaxolone in Women With Postpartum DepressionCompletedNCT03460756Phase 2Results posted
• A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum DepressionCompletedNCT03228394Phase 2Results posted
• Augmentation of Treatment-Resistant Depression With An Analog of the Neuroactive Steroid AllopregnanoloneCompletedNCT02900092Not applicableResults posted
• A Two-year Open-label Extension Study of Ganaxolone in Patients With Drug-resistant Partial-onset SeizuresTerminatedNCT02519439Phase 3Results posted
• Open-Label PoC Trial of Ganaxolone in Children With PCDH19 Female Pediatric Epilepsy and Other Rare Genetic EpilepsiesCompletedNCT02358538Phase 2Results posted
• Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label ExtensionCompletedNCT01963208Phase 3Results posted
• Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation CandidateCompletedNCT01857531Phase 2Results posted
• Ganaxolone Treatment in Children With Fragile X SyndromeCompletedNCT01725152Phase 2Results posted
• Ganaxolone in Posttraumatic Stress Disorder (PTSD)CompletedNCT01339689Phase 2Results posted
• A Treatment Use Protocol for Subjects Continuing on From the Open-label Extension 0601CompletedNCT01002820Phase 2Results posted
• Open-label Extension to Protocol 1042-0600CompletedNCT00512317Phase 2Results posted
• A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset SeizuresCompletedNCT00465517Phase 2Results posted
• Open-label Extension to Protocol 1042-0500TerminatedNCT00442104Phase 2Results posted
• A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile SpasmsCompletedNCT00441896Phase 2Results posted
• To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)WithdrawnNCT05814523Phase 3
• Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE)WithdrawnNCT05757544Phase 2

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