Florbetapir clinical trials
Also written Amyvid and 18F-AV-45.
How each study uses florbetapir is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- 14 Jan 2013 · Amyvid · EMEA/H/C/002422 (EMA)
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
35 studies that test it; most in 2012 (6)
| Year | Studies |
|---|---|
| 2007 | 2 |
| 2008 | 4 |
| 2009 | 5 |
| 2010 | 3 |
| 2011 | 4 |
| 2012 | 6 |
| 2013 | 2 |
| 2014 | 5 |
| 2017 | 1 |
| 2019 | 1 |
| 2021 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 27 · Other 8
Avid Radiopharmaceuticals (27) · University of California, San Francisco (1) · Centre Hospitalier Universitaire, Amiens (1) · University Hospital, Tours (1) · Invicro (1) · Institute for Neurodegenerative Disorders (1) · Universidad Central del Caribe (1) · The Cleveland Clinic (1)
Often tested with
Tested in the same studies.
Flortaucipir (1) · Pittsburgh compound B (1) · Fluorodeoxyglucose F18 (1) · Florbenazine F 18 (1) · Florzolotau F-18 (1)
Related medicines
As reviewed, each with the page that says it.
- One of Radiopharmaceuticals source
Studies
Open first, then newest update. How each study uses florbetapir is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 35
- B-amyloid as a Marker for GBM BioimagingNot yet recruitingPhase 2Universidad Central del CaribeNCT05820191Written as Amyvid, Intravenous Solution
- Cerebral Amyloid Imaging Using Florbetapir (AV-45)CompletedPhase 3Centre Hospitalier Universitaire, AmiensNCT02813434Written as florbetapir
- Depression in the Elderly and Cerebral Amyloid Plaques: Characterization by [18F] AV-45 Affectives Symptoms and Amyloïd Plaques (ASAP)CompletedNot applicableUniversity Hospital, ToursNCT01962753Written as 18FAV45
- Effects of Brain Beta-Amyloid on Postoperative CognitionActive, not recruitingPhase 4University of California, San FranciscoNCT01606488Written as Florbetapir F 18 (18F-AV-45)
- Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07CompletedPhase 3Avid RadiopharmaceuticalsNCT01447719Written as florbetapir F 18
- Plasma P-tau2017 and Quantitative Amyloid PET ImagingCompletedPhase 1InvicroNCT05164536Written as Amyvid
- Evaluation of Inter-reader Reliability Using Images From Subjects With Alzheimer's Disease (AD) or Mild Cognitive Impairment (MCI)CompletedPhase 3Avid RadiopharmaceuticalsNCT01565382Written as florbetapir F 18
- Study to Evaluate the Feasibility of [18F]Florbetapir PET for Assessment in MS PatientsCompletedPhase 4Institute for Neurodegenerative DisordersNCT01767493Written as [18F]Florbetapir PET imaging
- The Role of F-18 Florbetapir in the Early Detection of Cardiac AmyloidosisTerminatedPhase 4The Cleveland ClinicNCT03040427Written as F-18 florbetapir
- Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired SubjectsCompletedEarly Phase 1Avid RadiopharmaceuticalsNCT04474405Written as Florbetapir F 18
- Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18F-florbetapir (AV-45) PET ExaminationStatus unknownPhase 2Chang Gung Memorial HospitalNCT04305210Written as 18F-florbetapir
- Clinical Evaluation of Florbetapir F 18 (18F-AV-45)CompletedPhase 2Avid RadiopharmaceuticalsNCT01518374Written as Florbetapir F 18
- Florbetapir Calibration to the Centiloid ScaleCompletedPhase 1Avid RadiopharmaceuticalsNCT02120664Written as Florbetapir (18F)
- Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive DeclineCompletedPhase 4Avid RadiopharmaceuticalsNCT01703702Written as florbetapir (18F)
- Evaluation of Reader Training ProcessesCompletedPhase 4Avid RadiopharmaceuticalsNCT02051790Written as florbetapir F 18
- The Feasibility of Florbetapir Quantitation in EuropeCompletedPhase 4Avid RadiopharmaceuticalsNCT02107599Written as Florbetapir (18F)
- The Feasibility of Florbetapir QuantitationCompletedPhase 4Avid RadiopharmaceuticalsNCT01946243Written as Florbetapir F18
- Evaluation of Electronic Florbetapir (18F) Interpretation Training in Japanese PhysiciansWithdrawnNot applicableAvid RadiopharmaceuticalsNCT02029547Written as Florbetapir (18F)
- Imaging Characteristics of Florbetapir 18F in Patients With Frontotemporal Dementia, Alzheimer's Disease and Normal Controls.CompletedPhase 2Avid RadiopharmaceuticalsNCT01890343Written as florbetapir 18F
- A Phase II Trial of Florbetapir (18F) Positron Emission Tomography (PET) Imaging in Japan of Healthy Volunteers, Patients With Mild Cognitive Impairment (MCI) and Patients With Alzheimer's Disease (AD)CompletedPhase 2/3Avid RadiopharmaceuticalsNCT01662882Written as florbetapir (18F)
See all 35 studies that test florbetapir →
Given beside what is tested · 6 — florbetapir is usual care or a partner of the new treatment
- Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and TauNot yet recruitingPhase 1Columbia UniversityNCT06600880Written as Amyvid
- A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's DiseaseCompletedPhase 1Eli Lilly and CompanyNCT03019536Written as Florbetapir F 18
- Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD SubjectsCompletedPhase 2/3Avid RadiopharmaceuticalsNCT02016560Written as florbetapir F 18
- 18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic EncephalopathyCompletedPhase 2Avid RadiopharmaceuticalsNCT02079766Written as florbetapir F 18
- Imaging Characteristics of a Follow-up 18F-AV-1451 ScanTerminatedPhase 2Avid RadiopharmaceuticalsNCT02051764Written as Florbetapir F 18
- Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's DiseaseWithdrawnPhase 2SanofiNCT02667496Written as Florbetapir F18
Codes
What other systems call florbetapir · ClinicalTrials.gg INT005524
- MeSH (NLM) C545186florbetapirConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6867Q6IKODFLORBETAPIRConfirmed NLM, Wikidata
- RxNorm 1427225Confirmed FDA, Wikidata
- Wikidata Q27264221florbetapirConfirmed NLM, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C545186 | florbetapir | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6867Q6IKOD | FLORBETAPIR | Confirmed NLM, Wikidata |
| RxNorm | 1427225 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27264221 | florbetapir | Confirmed NLM, Wikidata |
Also registered as florbetapir f-18 (UNII 6W15Z5R0RU · RxNorm 1427224).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.