DrugBiological
Dalotuzumab clinical trials
Also written MK-0646.
- studies test it
- 19
- open now
- 0
- in phase 3
- 0
- first study started
- 2006
How studies write it
Studies that test it under each name
Studies by the year they started
19 studies that test it; most in 2008 (6)
| Year | Studies |
|---|---|
| 2006 | 2 |
| 2007 | 1 |
| 2008 | 6 |
| 2009 | 5 |
| 2010 | 3 |
| 2012 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 13 · Other 6
Merck Sharp & Dohme LLC (13) · M.D. Anderson Cancer Center (2) · NCIC Clinical Trials Group (1) · Memorial Sloan Kettering Cancer Center (1) · University of Kansas (1) · H. Lee Moffitt Cancer Center and Research Institute (1)
Often tested with
Tested in the same studies.
Ridaforolimus (3) · Erlotinib (2) · Cisplatin (1) · Etoposide (1) · Erlotinib Regimen (1) · Dasatinib (1)
Studies
Open first, then newest update. How each study uses dalotuzumab is read from its arms, and is right about nine times in ten.
Testing it · 19
- MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung CancerCompletedPhase 1/2NCIC Clinical Trials GroupNCT00869752Written as anti-IGF-1R recombinant monoclonal antibody MK-0646
- MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic CancerCompletedPhase 1/2M.D. Anderson Cancer CenterNCT00769483Written as MK-0646
- A Trial of Dalotuzumab in Combination With Irinotecan Versus Cetuximab and Irinotecan for Participants With Metastatic Rectal Cancers (mRC) (MK-0646-025)TerminatedPhase 2Merck Sharp & Dohme LLCNCT01609231Written as Dalotuzumab
- A Phase II Trial of Ridaforolimus and Exemestane, Compared to Ridaforolimus, Dalotuzumab and Exemestane in Participants With Breast Cancer (MK-8669-064)CompletedPhase 2Merck Sharp & Dohme LLCNCT01605396Written as Dalotuzumab
- A Dose-finding Study of Dalotuzumab in Subjects With Advanced Solid Tumors (MK-0646-002)CompletedPhase 1Merck Sharp & Dohme LLCNCT00635778Written as dalotuzumab
- Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016)CompletedPhase 1Merck Sharp & Dohme LLCNCT00925015Written as Dalotuzumab 10 mg/kg
- A Study of Dalotuzumab (MK-0646) in Breast Cancer Patients (MK-0646-013)CompletedPhase 1Merck Sharp & Dohme LLCNCT00759785Written as dalotuzumab (MK0646)
- A Study Evaluating Dalotuzumab (MK-0646) in Combination With Erlotinib for Participants With Non-Small Cell Lung Cancer (MK-0646-007)CompletedPhase 2Merck Sharp & Dohme LLCNCT00654420Written as Dalotuzumab
- Dose Escalation Trial of Dalotuzumab (MK-0646) in Advanced Solid Tumors and Multiple Myeloma (MK-0646-001)CompletedPhase 1Merck Sharp & Dohme LLCNCT00701103Written as Dalotuzumab
- Study of Dalotuzumab (MK-0646) in Adults With Solid Tumors (MK-0646-009)CompletedPhase 1Merck Sharp & Dohme LLCNCT00694356Written as Dalotuzumab
- Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Metastatic Colorectal Cancer (MK-0646-004)CompletedPhase 2Merck Sharp & Dohme LLCNCT00614393Written as dalotuzumab
- A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3)CompletedPhase 2Merck Sharp & Dohme LLCNCT01234857Written as ridaforolimus + dalotuzumab
- Phase I Imaging Study Evaluating Dalotuzumab (MK0646) in Combination With Erlotinib for Patients With Non-Small Cell Lung Cancer (MK-0646-008)CompletedPhase 1Merck Sharp & Dohme LLCNCT00729742Written as Comparator: erlotinib + dalotuzumab
- Clinical and Translational Study of MK-0646 in Patients With Metastatic Neuroendocrine Tumors (NET)CompletedPhase 2Memorial Sloan Kettering Cancer CenterNCT00610129Written as MK-0646
- A Combination Study With Ridaforolimus (MK8669) and Dalotuzumab (MK0646) in Patients With Advanced Cancer (8669-004)CompletedPhase 1Merck Sharp & Dohme LLCNCT00730379Written as Comparator: ridaforolimus + dalotuzumab
- Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast CancerTerminatedPhase 1/2M.D. Anderson Cancer CenterNCT00903006Written as MK-0646
- The Growth Factor Signature (GFS) as an Intermediate Biomarker of Response for Development of PI3K-Pathway Inhibitors in Patients With Breast Cancer (MK-8669-050)CompletedPhase 1Merck Sharp & Dohme LLCNCT01220570Written as Ridaforolimus + Dalotuzumab
- MK-0646 Insulin Growth Factor 1 Receptor Antibody in Stage IIIb or IV Metastatic Non-Squamous Lung CancerCompletedPhase 2University of KansasNCT00799240Written as Arm A: Pemetrexed Cisplatin
- FOLFOX/Bevacizumab +/- MK-0646 in Metastatic Colorectal CancerWithdrawnPhase 2H. Lee Moffitt Cancer Center and Research InstituteNCT01175291Written as MK-0646
Given in every arm · 3 — dalotuzumab is usual care beside what is tested
- A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)TerminatedPhase 1Merck Sharp & Dohme LLCNCT01243762Written as dalotuzumab
- Gemcitabine Hydrochloride and Carboplatin With or Without MK-0646 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerWithdrawnPhase 2Alliance for Clinical Trials in OncologyNCT00951444Written as dalotuzumab
- Study of Dalotuzumab Alone and With Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-062 AM1)CompletedPhase 1Merck Sharp & Dohme LLCNCT01431547Written as dalotuzumab
Codes
What other systems call dalotuzumab · ClinicalTrials.gg INT005973
- MeSH (NLM) C569480dalotuzumabConfirmed NLM, Wikidata
- UNII (FDA) 6YI1L648RHDALOTUZUMABConfirmed FDA, NLM, Wikidata
- RxNorm 1432293Confirmed FDA, Wikidata
- Wikidata Q5211586dalotuzumabConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C74011DalotuzumabConfirmed FDA, Wikidata
- DrugBank DB11840One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C569480 | dalotuzumab | Confirmed NLM, Wikidata |
| UNII (FDA) | 6YI1L648RH | DALOTUZUMAB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1432293 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5211586 | dalotuzumab | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C74011 | Dalotuzumab | Confirmed FDA, Wikidata |
| DrugBank | DB11840 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.