Cytochrome P-450 CYP3A Inhibitors: all 906 studies that test it

Page 8 of 10. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.

• A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal InfectionsCompletedNCT00647907Phase 4
• Comparative Study of 5 Days of M02-472 Clarithromycin Extended-Release Tablets to 7 Days of Clarithromycin Immediate-Release Tablets for the Treatment of Exacerbation of Chronic BronchitisCompletedNCT00645086Phase 3
• Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial SinusitisCompletedNCT00644553Phase 3
• A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Clarithromycin Extended Release for the Treatment of Pneumonia in Adult PatientsCompletedNCT00643227Phase 3
• Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South AfricaCompletedNCT00640887Phase 2
• External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain MetastasesStatus unknownNCT00637637Phase 2
• Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based RegimensCompletedNCT00627055Phase 4
• Lopinavir/Ritonavir Monotherapy in ChildrenCompletedNCT00626301Phase 4
• Antifungal Prophylaxis in Pediatric Acute LeukemiaStatus unknownNCT00624143Phase 3
• Pharmacokinetics of Low Dose RitonavirCompletedNCT00622206Phase 1/2
• Clinical Trial to Assess the Security of the Dose Reduction of Ritonavir in HIV-Infected Patients in Treatment With Tipranavir/Ritonavir 500/200 mg Every 12 HoursCompletedNCT00607958Phase 4
• Bioequivalency Study of Clarithromycin Tablets Under Fed ConditionsCompletedNCT00602498Not applicable
• Bioequivalency Study of Clarithromycin Tablets Under Fasting ConditionsCompletedNCT00601315Not applicable
• Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)CompletedNCT00600769Phase 4
• Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung DiseaseCompletedNCT00598897Phase 4
• Concentration of Itraconazole Solution in Nasal SecretionsCompletedNCT00588016Phase 1
• A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory SyndromeStatus unknownNCT00578825Not applicable
• Raltegravir Kaletra PharmacokineticsCompletedNCT00564772Phase 4
• Ketoconazole, Dexamethasone, and Hydrocortisone in Treating Patients With Prostate Cancer That Did Not Respond to Androgen-Deprivation TherapyWithdrawnNCT00559481Not applicable
• Comparison of Epzicom and Truvada for the Initial Once Daily HIV TreatmentCompletedNCT00544128Phase 4
• Measure of Pharmacokinetic Parameters and Adherence With MEMS in Naive HIV Infected Patients Treated With Reyataz Once Daily Combined With Norvir and TruvadaCompletedNCT00528060Phase 2
• HIV Antiretroviral Drugs and MetabolismStatus unknownNCT00525239Not applicable
• A Study of the Effects of Ketoconazole Taken Orally Has on the PK Profiles of a Dose of GSK189075 in Healthy VolunteersCompletedNCT00501397Phase 1
• Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.CompletedNCT00481182Phase 1
• Efficacy and Safety of SQV in Patients Who Have Chronic IDV NephrotoxicityCompletedNCT00477048Phase 2
• Pharmacokinetic and Efficacy of SQV/r 1500/100 Plus Tenofovir/Emtricitabine 300/200 mgWithdrawnNCT00476983Phase 2/3
• A PK and Salvage Study for Children With HIV-infectionCompletedNCT00476359Phase 4
• Helicobacter Pylori and Iron Deficiency: Prevalence of Association and Effect of TherapyWithdrawnNCT00475527Phase 4
• Evaluation Of SB-751689 Administered At Supratherapeutic Dose Levels In Healthy Adult Subjects.CompletedNCT00468689Phase 1
• Helicobacter Pylori Infection in Children With Chronic Idiopathic Thrombocytopenic PurpuraCompletedNCT00467571Phase 4
• Voriconazole as Prophylactic Therapy in Lung Transplant RecipientsTerminatedNCT00455364Phase 4
• Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate CancerTerminatedNCT00447473Phase 2
• Lopinavir Capsules to Kaletra or Invirase TabletsCompletedNCT00438152Phase 4
• SHARE: Simple HAART With Abacavir, Reyataz, and EpivirStatus unknownNCT00426296Phase 4
• A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive AspergillosisWithdrawnNCT00423163Phase 4
• Study Comparing Efficacy and Safety of Darunavir Boosted With Ritonavir to HART With 2 NRTI and Darunavir Boosted With Ritonavir in HIV-1 Infected Patients ANRS136CompletedNCT00421551Phase 3
• Relative Bioavailability of PM101 IV and Cordarone IVCompletedNCT00420953Phase 1
• The Pharmacokinetics and Safety of IDV/r With NRTIs in HIV/TB Co-infected Patients Receiving RifampicinCompletedNCT00411996Phase 1/2
• Study Of Healthy Subjects To Assess The Effect Of Ketoconazole And The Way The Body Will React To Casopitant [GW679769]CompletedNCT00404378Phase 1
• The Pharmacokinetics of Double Boosted Protease Inhibitors in Antiretroviral-naive HIV-1 Infected PatientsCompletedNCT00400738Phase 2
• Bioequivalence Study of Atazanavir 300 mg CapsuleCompletedNCT00393328Phase 1
• Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial FibrillationCompletedNCT00392431Not applicable
• BASIC: Boosted Atazanavir or Saquinavir Induced Lipid ChangesCompletedNCT00389402Phase 4
• Antifungal Use in Oncohematological Neutropenic PatientsCompletedNCT00386802Phase 4
• Immune Reconstitution in naïve HIV Patients With CD4 <100 Cells/mL When Treated With Lopinavir or Efavirenz.TerminatedNCT00386659Phase 4
• Study to Determine the Impact of Multiple Doses of Ketoconazole on Single-Dose Pharmacokinetics of HCV-796CompletedNCT00384917Phase 1
• Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected PatientsCompletedNCT00384904Phase 4
• Iv Amiodarone Versus Iv Procainamide to Treat Haemodynamically Well Tolerated Ventricular TachycardiaTerminatedNCT00383799Phase 4
• Use of Clarithromycin in Mustard-Induced BronchiolitisCompletedNCT00381147Phase 3
• Saquinavir/Ritonavir in Single Therapy as Maintenance TreatmentCompletedNCT00379405Phase 4
• Chronic Bronchiolitis or Resistant Asthma?CompletedNCT00368342Phase 4
• Drug Interaction Study With Famotidine, Atazanavir, and Atazanavir/Ritonavir/TenofovirCompletedNCT00365339Phase 1
• Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate RosiglitazoneCompletedNCT00362726Phase 1
• Drug Interaction Study With Proton Pump InhibitorCompletedNCT00357240Phase 1
• Dose Finding Confirmation of Atazanavir With Ritonavir and Efavirenz (ATV/RTV + EFV) in Healthy SubjectsCompletedNCT00357188Phase 1
• Pharmacokinetic (PK) Study of Single-dose Rosuvastatin and Tipranavir/Ritonavir in Healthy SubjectsCompletedNCT00344123Phase 1
• Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell TransplantationCompletedNCT00336531Phase 4
• Prospective Study of First-line Antibiotic Therapy for Early-stage Gastric MALT Lymphoma for Treatment OutcomeCompletedNCT00327132Not applicable
• Ketoconazole, Hydrocortisone, and GM-CSF in Treating Patients With Progressive Prostate Cancer After Hormone TherapyCompletedNCT00309894Phase 2
• Study to Determine the Pharmacokinetic Behavior of Antiretroviral Drugs in Patients Infected by HIVCompletedNCT00307502Phase 1
• Intravenous Clarithromycin in Septic SyndromeCompletedNCT00297674Phase 4
• N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent NeuroblastomaCompletedNCT00295919Phase 1
• A Study To Assess The Efficacy And Safety Of Voriconazole In Chinese Patients With Serious Deep Tissue Fungal InfectionsCompletedNCT00288197Phase 4
• Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)CompletedNCT00287209Phase 4
• Radiofrequency Catheter Ablation for Chronic Atrial FibrillationCompletedNCT00272636Not applicable
• Clarithromycin in Active Crohn's DiseaseCompletedNCT00269386Phase 3
• Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected ChildrenCompletedNCT00260078Phase 1/2
• GW640385 Plus Ritonavir And NRTIs For 48 Weeks In HIV-1 Infected AdultsCompletedNCT00257621Phase 2
• Amiodarone to Prevent Post-Operative ArrhythmiasCompletedNCT00251706Phase 3
• Outpatient Registry Trial of Respiratory Tract Infections in AdultsWithdrawnNCT00245453Phase 4
• Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00238225Phase 1
• Docetaxel Combined With Ketoconazole in Treatment of Breast CancerCompletedNCT00212095Phase 2
• A Pilot Study of the Treatment of Central Serous Chorioretinopathy With KetoconazoleCompletedNCT00211393Phase 2
• Macrolide Antibiotic Therapy for Patients With Cystic FibrosisCompletedNCT00205634Phase 2
• Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) InfectionStatus unknownNCT00197418Phase 2/3
• Salvage Therapy With Amprenavir, Lopinavir and Ritonavir in HIV-infected Patients in Virological Failure.CompletedNCT00196625Phase 2
• Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the VaginaCompletedNCT00194324Phase 4
• Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Combivir® in HIV-Negative Healthy SubjectsCompletedNCT00192621Phase 4
• Thalidomide, Dexamethasone, and Clarithromycin in Treating Patients With Multiple Myeloma Previously Treated With TransplantCompletedNCT00182663Phase 2
• A Study to Investigate the Pharmacokinetics, Safety and Tolerability of Voriconazole in ChildrenCompletedNCT00174473Phase 1/2
• ATV/Ritonavir Nevirapine Interaction (USPAC)CompletedNCT00162149Phase 1
• Lopinavir/r Monotherapy as Maintenance Therapy After Long Term Viral SuppressionCompletedNCT00160849Phase 4
• Voriconazole or Placebo in the Prophylaxis of Lung Infiltrates in Patients Undergoing Induction Chemotherapy for Acute Myelogenous LeukemiaTerminatedNCT00152594Phase 3
• Phase II Study of Biaxin, Revlimid, and Dexamethasone for Untreated Multiple MyelomaCompletedNCT00151203Phase 2
• An Open-Label Study To Assess The Pharmacokinetics, Safety And Toleration Of Vfend®; Following Multiple Dosing With VfendTerminatedNCT00150319Phase 1/2
• Tailored Treatment of H. Pylori Infection Based Polymorphisms of CYP2C19 and 23S rRNA of H. PyloriStatus unknownNCT00149084Phase 3
• A Pharmacokinetic (PK) Study of a Combination of Indinavir, Ritonavir, and AmprenavirCompletedNCT00148785Phase 4
• The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-infected Pregnant Women.CompletedNCT00145561Phase 1/2
• Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV SubjectsTerminatedNCT00144833Phase 3
• Safety Study of Tipranavir Co-administered With Low-dose Ritonavir (TPV/r) in Patients With Advanced HIV-1 Infection and Limited Treatment OptionsCompletedNCT00144287Phase 3
• NRTI-Sparing Pilot StudyCompletedNCT00143689Phase 4
• Assessment of Voriconazole Penetration Into the Brain by Fluorine-Magnetic Resonance SpectroscopyCompletedNCT00136968Phase 1
• Effect of HIV Protease Inhibitor Drugs on Glucose and Insulin MetabolismCompletedNCT00135434Phase 1
• A Phase IIIb Study Comparing Two Boosted Protease Inhibitor-based HAART Regimens in HIV-infected Patients Experiencing Their First Virologic Failure While Receiving an NNRTI-containing HAART RegimenCompletedNCT00135395Phase 3
• Dual Boosted Protease Inhibitor Regimens Without Any Additional Antiretroviral Therapy in HIV-1 Infected Patients (ANRS127)CompletedNCT00122603Phase 2
• Efficacy and Safety of Tenofovir DF/Atazanavir Enhanced With Low Dose of Ritonavir in HIV-Infected PatientsTerminatedNCT00122577Phase 2
• The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart DiseaseCompletedNCT00121550Phase 3
• Safety, Tolerability, and Blood Levels of Ritonavir-Boosted Atazanavir and Rifampin When Taken Together in HIV Uninfected AdultsCompletedNCT00096850Not applicable
• Ixabepilone and Ketoconazole in Treating Patients With Advanced Solid TumorsCompletedNCT00096317Phase 1
• KALETRA Or LEXIVA With Ritonavir Combined With EPIVIR And Abacavir In Naive Subjects Over 48 WeeksCompletedNCT00085943Phase 3

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