Cytochrome P-450 CYP3A Inhibitors: all 906 studies that test it

Page 9 of 10. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.

• Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIVCompletedNCT00084058Phase 1/2
• Atazanavir/Ritonavir Maintenance TherapyCompletedNCT00084019Not applicable
• Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT00079222Not applicable
• Voriconazole in Preventing Fungal Infections in Children With Neutropenia After ChemotherapyCompletedNCT00066599Phase 2
• Voriconazole With or Without Interferon Gamma in Treating Patients With Aspergillosis or Other Fungal InfectionsCompletedNCT00059878Phase 2
• Dual Boosted - Protease Inhibitor (PI) Pharmacokinetics (PK) Trial (Tipranavir / Ritonavir) in Highly Treatment-experienced HIV-1 Infected PatientsCompletedNCT00056641Phase 2
• Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy VolunteersCompletedNCT00050180Phase 4
• Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug ResistanceCompletedNCT00046033Phase 2
• Lopinavir/Ritonavir in Combination With Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral HIV-Infected SubjectsCompletedNCT00043953Phase 2
• Study to Explore Safety And Tolerability of Fosamprenavir With or Without Ritonavir in Combination With TRIZIVIR or COMBIVIRCompletedNCT00043888Phase 3
• A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase InhibitorsCompletedNCT00038636Phase 3
• Amprenavir/Ritonavir, Saquinavir/Ritonavir or Efavirenz in HIV-Infected Subjects Following Failure With Kaletra (ABT-378/Ritonavir) as Their First Protease Inhibitor Based HAARTCompletedNCT00038532Phase 2
• Amprenavir/Ritonavir or Saquinavir/Ritonavir in HIV-Infected Subjects Following Failure With Kaletra as Their Second Protease InhibitorCompletedNCT00038519Phase 2/3
• Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate CancerCompletedNCT00030654Phase 3
• Dual Versus Triple Protease Inhibitor Combinations, Including Ritonavir, in HIV Infected PeopleCompletedNCT00028366Not applicable
• Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate CancerCompletedNCT00027859Phase 3
• Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIVCompletedNCT00027339Phase 2
• Comparison of Two Dosing Regimens of GW433908/Ritonavir Versus Lopinavir/Ritonavir for 48 Weeks in HIV Patients Who Have Taken Protease Inhibitors and Experienced Virological FailureStatus unknownNCT00025727Phase 3
• Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate CancerTerminatedNCT00019695Phase 2
• Emergency Use of Voriconazole in Patients With Life-Threatening Invasive Fungal InfectionsCompletedNCT00015665Phase 3
• Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate CancerCompletedNCT00014352Phase 2
• Ritonavir and Indinavir in Children Failing Other Anti-HIV TreatmentCompletedNCT00012519Phase 1/2
• Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral DrugsStatus unknownNCT00009061Phase 3
• Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus RhythmCompletedNCT00007605Phase 3
• Ritonavir and Agenerase Treatment for Patients Who Have Failed Previous Anti-HIV TreatmentStatus unknownNCT00006591Not applicable
• Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV DrugsStatus unknownNCT00006397Phase 3
• A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate CancerTerminatedNCT00006371Phase 2
• A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV InfectionCompletedNCT00006154Phase 3
• Voriconazole to Prevent Systemic Fungal Infections in ChildrenCompletedNCT00005912Phase 1
• A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of AspergillomaCompletedNCT00005668Phase 2
• The Safety and Effectiveness of Indinavir Plus Ritonavir Plus Two NRTIs in HIV-Infected Patients Who Need Early Intervention TreatmentStatus unknownNCT00005118Phase 2
• Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and SporotrichosisCompletedNCT00004811Phase 1/2
• Effects of Miconazole on Blood FlowCompletedNCT00004575Phase 1
• Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow TransplantationCompletedNCT00003883Phase 3
• Carboxyamidotriazole and Ketoconazole in Treating Patients With Advanced CancersCompletedNCT00003249Phase 1
• Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate CancerCompletedNCT00003084Phase 2
• Comparison of Voriconazole and Amphotericin B in Treating Patients With AspergillosisCompletedNCT00003031Phase 3
• Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate CancerCompletedNCT00002855Phase 3
• Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate CancerCompletedNCT00002760Phase 3
• Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the StomachCompletedNCT00002682Phase 2
• Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV DrugsStatus unknownNCT00002451Phase 2
• A Study to Compare the Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected PatientsCompletedNCT00002448Phase 3
• A Study to Compare Two Anti-HIV Drug CombinationsCompletedNCT00002447Phase 3
• A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected PatientsCompletedNCT00002438Not applicable
• The Safety and Effectiveness of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV DrugsCompletedNCT00002425Phase 4
• A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients With HIV-Associated Kidney DiseaseCompletedNCT00002397Phase 3
• A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected PatientsCompletedNCT00002383Phase 1
• A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected PatientsCompletedNCT00002382Phase 3
• The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and ChildrenCompletedNCT00002380Phase 1
• A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected PatientsCompletedNCT00002378Phase 3
• A Study of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs in HIV-1 Infected PatientsCompletedNCT00002374Phase 3
• Study of Itraconazole in Patients With Advanced HIV InfectionCompletedNCT00002370Not applicable
• A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV DrugsCompletedNCT00002367Phase 3
• The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's SarcomaCompletedNCT00002366Phase 2
• Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease InhibitorsCompletedNCT00002361Phase 2
• A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With FluconazoleCompletedNCT00002341Not applicable
• The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium Avium Complex (MAC) Infection in HIV-Infected PatientsCompletedNCT00002336Not applicable
• A Study of Zidovudine (AZT) Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients With Little or No Previous TreatmentCompletedNCT00002334Phase 3
• A Study of Saquinavir and Zalcitabine, Used Alone and Together, in the Treatment of Advanced HIV Infection in Patients Who Stopped Taking or Who Cannot Take ZidovudineCompletedNCT00002333Phase 2
• The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDSCompletedNCT00002331Not applicable
• A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune SystemsCompletedNCT00002304Not applicable
• Safety and Effectiveness of an Anti-HIV Drug Combination Taken Twice DailyStatus unknownNCT00002241Phase 2
• A Study to Compare Three Doses of T-20 When Given in Combination With Abacavir, Amprenavir, Ritonavir, and Efavirenz to HIV-Infected AdultsCompletedNCT00002239Phase 2
• Safety and Effectiveness of Adding Saquinavir (FORTOVASE) in Soft Gel Capsule Form to an Anti-HIV Drug Combination in HIV-Infected PatientsCompletedNCT00002229Phase 4
• A Study of Ritonavir/Indinavir Combination in HIV-Infected PatientsCompletedNCT00002223Not applicable
• A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected PatientsCompletedNCT00002201Not applicable
• An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.CompletedNCT00002194Phase 1
• A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected PatientsCompletedNCT00002190Phase 2
• A Phase IIIB Open-Label, Comparative Study to Evaluate Saquinavir Soft Gel Capsule (SGC) Treatment in Combination With Other Antiretrovirals in HIV-1 Infected Antiretroviral-Naive PatientsCompletedNCT00002178Phase 3
• A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral DrugsCompletedNCT00002162Phase 2
• A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or HistoplasmosisCompletedNCT00002159Phase 3
• A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs PatientsCompletedNCT00002140Phase 3
• An Open Study of the Effect of Itraconazole Oral Solution for the Treatment of Fluconazole Refractory Oropharyngeal Candidiasis in HIV-Positive Subjects.CompletedNCT00002133Not applicable
• Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.CompletedNCT00002132Not applicable
• A Dose-Escalating Study of Ro 31-8959 ( HIV Protease Inhibitor ) in Patients With HIV Disease.CompletedNCT00002111Phase 1
• A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or PlaceboCompletedNCT00002101Phase 3
• Once-Daily Drug Regimen for HIV-Infected PatientsCompletedNCT00001968Phase 1
• Voriconazole to Treat Fungal InfectionsCompletedNCT00001940Phase 3
• An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal InfectionsCompletedNCT00001810Phase 3
• An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal InfectionsCompletedNCT00001757Phase 3
• A Pilot Study of the Immunologic Reconstitution in HIV-1 Infected Children Receiving Highly Active Antiretroviral Therapy With Combination Ritonavir, Nevirapine and StavudineCompletedNCT00001688Phase 2
• Voriconazole vs. Amphotericin B in the Treatment of Invasive AspergillosisCompletedNCT00001646Phase 3
• Itraconazole for the Prevention of Fungal Infections in Chronic Granulomatous DiseaseCompletedNCT00001280Phase 2
• Safety and Tolerance of Indinavir Plus Ritonavir in HIV-Positive Patients Failing Therapy With Amprenavir, Nelfinavir, or SaquinavirCompletedNCT00001133Phase 1
• A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected PatientsWithdrawnNCT00001094Phase 2
• Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV DrugsCompletedNCT00001083Phase 2
• The Effectiveness of Ritonavir Plus Zidovudine Plus Lamivudine in HIV-Infected PatientsCompletedNCT00001075Not applicable
• A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDSCompletedNCT00001058Phase 2
• The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 3
• The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected PatientsCompletedNCT00001023Not applicable
• A Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000992Phase 1
• A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000975Phase 2
• The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDSCompletedNCT00000971Phase 1
• A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and ChildrenCompletedNCT00000952Phase 1
• Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIVCompletedNCT00000940Phase 2
• Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their NewbornsCompletedNCT00000920Phase 1
• A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive ChildrenCompletedNCT00000913Phase 2
• The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and SaquinavirCompletedNCT00000898Not applicable
• A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used IndinavirCompletedNCT00000892Not applicable
• Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their BabiesCompletedNCT00000888Phase 1

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