Drug
Colistin clinical trials
Also written polymyxin e.
- studies test it
- 30
- open now
- 3
- in phase 3
- 12
- first study started
- 2001
Keep track of what changes. Save the Colistin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
30 studies that test it; most in 2009 (3)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2006 | 2 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 2 |
| 2012 | 3 |
| 2013 | 2 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 3 |
| 2017 | 1 |
| 2019 | 1 |
| 2021 | 3 |
| 2022 | 2 |
| 2025 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 1
- Phase 2
- 3
- Phase 3
- 12
- Phase 4
- 10
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 30
Mahidol University (6) · National Jewish Health (1) · Tanta University (1) · Beni-Suef University (1) · University of Michigan (1) · Nourhan Hassan Osama Thuraya Mohamed (1) · Rambam Health Care Campus (1) · Poitiers University Hospital (1)
Often tested with
Tested in the same studies.
Meropenem (2) · Colistinmethanesulfonic acid (2) · Fosfomycin (2) · Norfloxacin (1) · Nitazoxanide (1) · Imipenem (1) · Ciprofloxacin (1) · Polymyxin B (1)
Studies
Open first, then newest update. How each study uses Colistin is read from its arms, and is right about nine times in ten.
Testing it · 30
- Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke PatientsNot yet recruitingEarly Phase 1Ain Shams UniversityNCT07865871Written as Inhaled colistin
- Inhaled Colistin to Prevent Ventilator-Associated Pneumonia in Patients With Acute Brain InjuryRecruitingNot applicableSoutheast University, ChinaNCT06819462Written as Inhaled colistin
- Optimising TREATment for Severe Gram-Negative Bacterial InfectionsRecruitingPhase 4National University of SingaporeNCT07004049Written as Colistin/Polymyxin B + Sulbactam
- IV Colistin for Pulmonary Exacerbations: Improving Safety and EfficacyCompletedPhase 4National Jewish HealthNCT02918409Written as Colistin
- Comparative Study of Secondary Prophylaxis for SBPCompletedPhase 4Tanta UniversityNCT06827756Written as Colistin
- Pharmacokinetics of Colistin in Critically Ill Patients With Extracorporeal Membrane OxygenationTerminatedPhase 4St. Anne's University Hospital Brno, Czech RepublicNCT05542446Written as Colistin
- Aerosolized Versus Intravenous Colistin-based Antimicrobial Regimens in Hospitalized COVID-19 Patients With Bacterial Coinfection: A Randomized Controlled TrialCompletedPhase 3Beni-Suef UniversityNCT05689229Written as Colistin
- Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)CompletedPhase 3University of MichiganNCT01597973Written as colistin and meropenem
- Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic PatientsStatus unknownEarly Phase 1Madonna Magdy FahmyNCT05279586Written as colistin
- Colistin Intravenous Administration in Critically Ill Patients Suffering From Hospital Infections Caused by Multi-antibiotic-resistant Germs.Status unknownPhase 4Fondazione Policlinico Universitario Agostino Gemelli IRCCSNCT04995133Written as Colistin
- Nebulized Colistin for Gram Negative VAP Prevention.Status unknownNot applicableUniversity of ThessalyNCT04208945Written as Colistin
- Nebulized and Intravenous Colistin in Ventilator Associated-pneumoniaTerminatedPhase 3Assistance Publique - Hôpitaux de ParisNCT02906722Written as Intravenous colimycin
- The Effect of Colistin Inhalation on Ventilator Associated PneumoniaCompletedPhase 2/3Nourhan Hassan Osama Thuraya MohamedNCT03622450Written as Colistin
- Efficacy and Mortality of a Loading Dose of Colistin in Critical Ill PatientsStatus unknownPhase 4Hospital Barros Luco TrudeauNCT02117986Written as colistin
- Eradication of Antibiotic-resistant Bacteria Through Antibiotics and Fecal BacteriotherapyStatus unknownPhase 2Stephen HarbarthNCT02472600Written as Colistin
- A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).CompletedNot applicableRambam Health Care CampusNCT01266499Written as Colistin (Polymyxin E) 100mg x 4/d
- Population Pharmacokinetic Study of Colistin in Patients Infected With Multiresistant Gram-negative BacteriaCompletedPhase 1Poitiers University HospitalNCT01060891Written as colimycin
- Effect of Aerosolised Colistin in Ventilator Associated PneumoniaCompletedPhase 4Tunis UniversityNCT02683603Written as AS colimycin (colistin)
- Trial of Colistin Versus Meropenem in Ventilator-associated Pneumonia (VAP) (CR-GNB)CompletedPhase 3Fundación Pública Andaluza para la gestión de la Investigación en SevillaNCT01292031Written as Colistin
- Therapy of Ventilator-associated Tracheobronchitis Caused by Gram Negative Bacteria With Nebulized ColistinStatus unknownPhase 3Mahidol UniversityNCT02619786Written as Inhaled colistin
See all 30 studies that test Colistin →
Given in every arm · 7 — Colistin is usual care beside what is tested
- The Effect of Curcumin Against Colistin-induced NephrotoxicityRecruitingPhase 3October 6 UniversityNCT05613361Written as Colistin
- Efficacy of Colistin Monotherapy Versus Colistin Plus Minocycline for Carbapenem-Resistant A. Baumannii InfectionStatus unknownPhase 4Mahidol UniversityNCT05586815Written as Colistin
- A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.Status unknownNot applicableInstitute of Liver and Biliary Sciences, IndiaNCT04208763Written as Colistin
- Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella PneumoniaeStatus unknownPhase 4Al-Azhar UniversityNCT04489459Written as Colistin
- Combined Dry Powder Tobramycin and Nebulized Colistin Inhalation in CF PatientsCompletedPhase 3University Hospital TuebingenNCT03341741Written as Colistin
- Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus MeropenemCompletedPhase 4Mical PaulNCT01732250Written as Colistin
- Colistin and Rifampicin for MDR-AcinetobacterCompletedPhase 3University of Campania Luigi VanvitelliNCT01577862Written as Colistin
As the comparator · 7 — what is tested is compared with Colistin
- Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus ComplexRecruitingPhase 3BioVersys SASNCT07326540Written as Colistin
- Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. BaumanniiRecruitingPhase 4Rambam Health Care CampusNCT05922124Written as Colistin
- Colistin Versus Colistin Combined With Cefoperazone-sulbactam for Multiresistant Acinetobactor Baumannii Ventilator-associated Pneumonia TreatmentCompletedNot applicableShaheed Mohtarma Benazir Bhutto Institue of TraumaNCT07671755Written as Colistin
- Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae InfectionsTerminatedPhase 3King Faisal Specialist Hospital & Research CenterNCT05258851Written as Colistin
- Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus ComplexCompletedPhase 3Entasis TherapeuticsNCT03894046Written as Colistin
- A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)CompletedPhase 3Achaogen, Inc.NCT01970371Written as colistin
- Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in NeonatesTerminatedPhase 3Hat Yai Medical Education CenterNCT02806141Written as Intravenous colistin
Codes
What other systems call Colistin · ClinicalTrials.gg INT007251
- MeSH (NLM) D003091ColistinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Z67X93HJG1COLISTINConfirmed FDA, NLM, Wikidata
- RxNorm 2709Confirmed FDA, Wikidata
- Wikidata Q418946colistinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C65350ColistinConfirmed FDA, Wikidata
- DrugBank DB00803One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003091 | Colistin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Z67X93HJG1 | COLISTIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2709 | — | Confirmed FDA, Wikidata |
| Wikidata | Q418946 | colistin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C65350 | Colistin | Confirmed FDA, Wikidata |
| DrugBank | DB00803 | — | One source Wikidata |
Also registered as colistin sulfate (UNII WP15DXU577 · RxNorm 2710).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.