Drug
Ceftolozane clinical trials
Also written CXA-101.
- studies test it
- 17
- open now
- 2
- in phase 3
- 3
- first study started
- 2009
Keep track of what changes. Save the ceftolozane studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Combined with it in one product
Studies by the year they started
17 studies that test it; most in 2018 (4)
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2010 | 2 |
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 4 |
| 2019 | 1 |
| 2020 | 1 |
| 2023 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 4
- Phase 2
- 6
- Phase 3
- 3
- Phase 4
- 4
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 8
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (5) · Merck Sharp & Dohme LLC (4) · M.D. Anderson Cancer Center (1) · Royal Brisbane and Women's Hospital (1) · Joseph L. Kuti, PharmD (1) · Hartford Hospital (1) · Sunshine Coast Hospital and Health Service (1) · Instituto Nacional de Cancerologia de Mexico (1)
Often tested with
Tested in the same studies.
Ceftolozane, tazobactam drug combination (13) · Metronidazole (3) · Tazobactam (2)
Studies
Open first, then newest update. How each study uses ceftolozane is read from its arms, and is right about nine times in ten.
Testing it · 17
- Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological PatientsRecruitingNot applicableInstituto Nacional de Cancerologia de MexicoNCT06422533Written as Ceftolozane/tazobactam
- Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and BronchiectasisNot yet recruitingPhase 4Sunshine Coast Hospital and Health ServiceNCT06035055Written as Ceftolozane/tazobactam
- Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell TransplantationTerminatedPhase 4Weill Medical College of Cornell UniversityNCT04673175Written as Ceftolozane / Tazobactam Injection
- Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)CompletedPhase 1Merck Sharp & Dohme LLCNCT04223752Written as Ceftolozane/Tazobactam
- MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)CompletedPhase 2Merck Sharp & Dohme LLCNCT03230838Written as Ceftolozane/Tazobactam
- MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)CompletedPhase 2Merck Sharp & Dohme LLCNCT03217136Written as Ceftolozane/Tazobactam
- Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015)CompletedPhase 3Merck Sharp & Dohme LLCNCT03830333Written as Ceftolozane/Tazobactam
- Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-TazobactamCompletedPhase 2M.D. Anderson Cancer CenterNCT03485950Written as Ceftolozane
- Pharmacokinetics of Ceftolozane/Tazobactam in Patients With BurnsTerminatedPhase 4Texas Tech University Health Sciences CenterNCT03002506Written as Ceftolozane/tazobactam
- Pharmacokinetics of Ceftolozane/Tazobactam in Plasma and Cerebrospinal FluidCompletedPhase 1/2Royal Brisbane and Women's HospitalNCT03309657Written as Ceftolozane/tazobactam
- Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis PatientsCompletedPhase 4Joseph L. Kuti, PharmDNCT02421120Written as Ceftolozane/Tazobactam
- Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)CompletedPhase 3Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT02070757Written as Ceftolozane/tazobactam
- Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb InfectionsCompletedPhase 1Hartford HospitalNCT02620774Written as Ceftolozane/tazobactam
- Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated PneumoniaTerminatedPhase 3Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT01853982Written as Ceftolozane/Tazobactam
- Safety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Intraabdominal InfectionsCompletedPhase 2Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT01147640Written as CXA-101/ tazobactam and metronidazole
- Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract InfectionsCompletedPhase 2Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT00921024Written as CXA-101
- Safety Study Designed to Study the Effects of Two Different Doses of CXA-101/Tazobactam, a Low Dose and a High Dose, on the QT/QTc Intervals in Healthy SubjectsCompletedPhase 1Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)NCT02508753Written as CXA-101/tazobactam
Codes
What other systems call ceftolozane · ClinicalTrials.gg INT005077
- MeSH (NLM) C519491ceftolozaneConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 37A4IES95QCEFTOLOZANEConfirmed FDA, NLM, Wikidata
- RxNorm 1597609Confirmed FDA, Wikidata
- Wikidata Q21011231ceftolozane/tazobactamConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C150024CeftolozaneOne source FDA
- DrugBank DB09050One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C519491 | ceftolozane | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 37A4IES95Q | CEFTOLOZANE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1597609 | — | Confirmed FDA, Wikidata |
| Wikidata | Q21011231 | ceftolozane/tazobactam | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C150024 | Ceftolozane | One source FDA |
| DrugBank | DB09050 | — | One source Wikidata |
Also registered as ceftolozane sulfate (UNII 7R247U84HY · RxNorm 1597608).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.