Beta-Lactamase Inhibitors: all 294 studies that test it
Page 1 of 3. Open to participants first (48), then studies with results posted, then the rest; newest registration first within each.
- Amoxicillin-clavulanate Versus Amoxicillin Versus Placebo in Acute Otitis Media in ChildrenNot yet recruitingNCT07878910Phase 4
- Comparison of Topical Antibiotics Versus Systemic Antibiotics in Preventing Burn Wound Infection in Pediatric Burn PatientsNot yet recruitingNCT07870239Not applicable
- Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated AppendicitisNot yet recruitingNCT07869095Phase 3
- Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE)Not yet recruitingNCT07857252Phase 2
- Targeted Versus Standard Peri-operative Antibiotic Prophylaxis in Patients Colonized With Carbapenemase Producing Enterobacterales Undergoing Liver TransplantationNot yet recruitingNCT07759453Phase 3
- Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Sinusitis)RecruitingNCT07732699Phase 4
- Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media)RecruitingNCT07730814Phase 4
- Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal AbscessNot yet recruitingNCT07704359Phase 4
- Prophylactic Antibiotics in Preventing Surgical Site Infection After Hepatobiliary Surgery in High-Resistant SettingsRecruitingNCT07620223Not applicable
- Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in ChildrenNot yet recruitingNCT07587450Phase 3
- Finnish Children´s Protracted CoughRecruitingNCT07582549Phase 3
- Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma.RecruitingNCT07556991Phase 2/3
- The Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)RecruitingNCT07556107Phase 4
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform TrialNot yet recruitingNCT07485010Phase 2
- Efficacy of an Empirical Treatment With Amoxicillin-clavulanate (AC) Compared to the Combination Amoxicillin-clavulanate and Ciprofloxacin (AC+C) in the Outpatient Care of Chemotherapy-induced Fever in Adult Haematology Patients.Not yet recruitingNCT07483736Phase 3
- Subcutaneous Piperacillin/Tazobactam Compared With Intravenous TreatmentRecruitingNCT07481539Phase 2
- A Study to Evaluate the Efficacy and Safety of Meropenem and Pralurbactam in HABP/VABPRecruitingNCT07327619Phase 3
- Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig)RecruitingNCT07202091Phase 2/3
- Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in Carbapenem-Resistant Enterobacteriaceae InfectionsRecruitingNCT07089186Phase 3
- Optimising TREATment for Severe Gram-Negative Bacterial InfectionsRecruitingNCT07004049Phase 4
- Appropriateness of Antibiotic Combination Therapy for Severe Community-acquired Pneumonia in South KoreaNot yet recruitingNCT06977347Not applicable
- A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized PatientsRecruitingNCT06954129Phase 4
- A Multicenter Clinical Study on the Continuous vs. Intermittent Infusion of Ceftazidime-Avibactam in Critically Ill Patients With Severe InfectionsNot yet recruitingNCT06939829Phase 4
- A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract InfectionsRecruitingNCT06828848Phase 2
- Comparison of Efficacy and Safety of Ceftazidime Avibactam Versus Extended Infusions of High Dose Meropenem in Patients of ACLF With Nosocomial Infections.Not yet recruitingNCT06818565Not applicable
- A Study to Assess Sulbactam-durlobactam in Pediatric Patients With Acinetobacter Baumannii-calcoaceticus Complex InfectionRecruitingNCT06801223Phase 1
- Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose CombinationRecruitingNCT06733675Phase 1
- Aminoglycosides in Early SepsisRecruitingNCT06712641Phase 4
- Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric ProphylaxisRecruitingNCT06709196Phase 4
- Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAINot yet recruitingNCT06633718Phase 3
- Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAPRecruitingNCT06494072Phase 4
- Therapeutic Options for CRABRecruitingNCT06440304Phase 4
- Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological PatientsRecruitingNCT06422533Not applicable
- Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing PathogensRecruitingNCT06342115Phase 4
- Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With AntibioticsNot yet recruitingNCT06250413Not applicable
- Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary StentNot yet recruitingNCT06123169Phase 3
- Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute SinusitisRecruitingNCT06076304Phase 4
- Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and BronchiectasisNot yet recruitingNCT06035055Phase 4
- Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis.RecruitingNCT05981079Phase 4
- Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown LengtheningNot yet recruitingNCT05925179Phase 4
- CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)RecruitingNCT05846399Phase 4
- Fast Track Therapeutic Model in Acute Complicated Appendicitis in PediatricsRecruitingNCT05761080Phase 4
- Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or ExtensionRecruitingNCT05678621Phase 2/3
- The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for TuberculosisRecruitingNCT05664568Phase 2
- Fast-track Blood Test for Suspected Fever by Deficiency of a Kind of White Blood Cells As Main Defense Against InfectionRecruitingNCT05393505Phase 4
- Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIsRecruitingNCT05224401Phase 3
- PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)RecruitingNCT03671967Phase 4
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
- A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)CompletedNCT06059846Phase 3Results posted
- eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPFTerminatedNCT05753735Phase 2Results posted
- Early Antibiotics After Aspiration in ICU PatientsTerminatedNCT05079620Phase 4Results posted
- PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONINCompletedNCT04983901Phase 2Results posted
- Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell TransplantationTerminatedNCT04673175Phase 4Results posted
- Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic AcidCompletedNCT04411914Phase 1Results posted
- Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)CompletedNCT04223752Phase 1Results posted
- Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial PneumoniaTerminatedNCT04040621Phase 1Results posted
- A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With AztreonamCompletedNCT03978091Phase 1/2Results posted
- Safety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)CompletedNCT03969901Phase 2/3Results posted
- Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus ComplexCompletedNCT03894046Phase 3Results posted
- Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015)CompletedNCT03830333Phase 3Results posted
- Antibiotic Duration in Post-appendectomy AbscessTerminatedNCT03795194Phase 4Results posted
- Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)CompletedNCT03788967Phase 3Results posted
- Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)CompletedNCT03583333Phase 3Results posted
- Use of Perioperative Antibiotics in Endoscopic Sinus SurgeryTerminatedNCT03369717Phase 4Results posted
- Pharmacokinetics of Ceftolozane/Tazobactam in Plasma and Cerebrospinal FluidCompletedNCT03309657Phase 1/2Results posted
- Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)CompletedNCT03293485Phase 3Results posted
- Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated AppendicitisCompletedNCT03289351Phase 4Results posted
- Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?CompletedNCT03269994Phase 3Results posted
- A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)CompletedNCT03230916Phase 1Results posted
- MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)CompletedNCT03230838Phase 2Results posted
- MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)CompletedNCT03217136Phase 2Results posted
- Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TBCompletedNCT03174184Phase 2Results posted
- Pharmacokinetics of Ceftolozane/Tazobactam in Patients With BurnsTerminatedNCT03002506Phase 4Results posted
- Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in ChildrenCompletedNCT02891915Phase 4Results posted
- A Study of Avycaz (Ceftazidime/Avibactam) Pharmacokinetics/Pharmacodynamics (PK/PD) in Critically Ill PatientsCompletedNCT02822950Phase 1Results posted
- Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With CancerTerminatedNCT02732327Phase 2Results posted
- Role of Intravenous Versus Home Oral Antibiotics in Perforated AppendicitisCompletedNCT02724410Not applicableResults posted
- Reduced Clavulanate Formulation of Amoxicillin-Clavulanate in Children 6-23 Months With Acute Otitis MediaCompletedNCT02630992Phase 3Results posted
- Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb InfectionsCompletedNCT02620774Phase 1Results posted
- Clavulanic Acid (CLAV) and Cocaine Interaction Safety StudyCompletedNCT02563769Phase 1Results posted
- Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit?CompletedNCT02554383Phase 3Results posted
- Preschool Wheeze: Inflammation/Infection Guided ManagementCompletedNCT02517099Phase 2Results posted
- Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic FibrosisCompletedNCT02504827Phase 4Results posted
- Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)CompletedNCT02493764Phase 3Results posted
- Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013)CompletedNCT02452047Phase 3Results posted
- Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis PatientsCompletedNCT02421120Phase 4Results posted
- Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/ClavulanateCompletedNCT02340000Phase 4Results posted
- Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in AdultsCompletedNCT02168946Phase 3Results posted
- Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and APCompletedNCT02166476Phase 3Results posted
- AUGMENTIN™ in Dental InfectionsCompletedNCT02141217Phase 4Results posted
- Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)CompletedNCT02070757Phase 3Results posted
- Antibiotic Safety (SCAMP)CompletedNCT01994993Phase 2/3Results posted
- Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial RhinosinusitisCompletedNCT01934231Phase 3Results posted
- PK/PD of High Dose Pip/Tazo in Obese PatientsCompletedNCT01923363Not applicableResults posted
- Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled TrialCompletedNCT01919411Phase 4Results posted
- Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed InfectionsCompletedNCT01893346Phase 1Results posted
- Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated PneumoniaTerminatedNCT01853982Phase 3Results posted
- Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd InfectionsCompletedNCT01726023Phase 3Results posted
- Continuous Infusion Piperacillin-tazobactam for the Treatment of Cystic FibrosisTerminatedNCT01694069Phase 4Results posted
- To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)CompletedNCT01689207Phase 1Results posted