ACE inhibitors: all 391 studies that test it

Page 2 of 4. Open to participants first (24), then studies with results posted, then the rest; newest registration first within each.

• Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.CompletedNCT00153101Phase 4Results posted
• Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)CompletedNCT00141778Phase 2/3Results posted
• Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart NetworkCompletedNCT00113087Phase 3Results posted
• The CLEVER Study - Coreg And Left Ventricular Mass RegressionCompletedNCT00108082Phase 3Results posted
• Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without ChemotherapyTerminatedNCT00077064Phase 2Results posted
• Effect of Continuing vs. Discontinuing ACE Inhibitors on Renal Function After Coronary AngiographyCompletedNCT07184918Not applicable
• A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of CaptoprilCompletedNCT06292091Phase 1
• Effects of Traditional Chinese Medicine (GSJYF) in Children With Inherited Proteinuric Kidney DiseaseCompletedNCT05759754Not applicable
• Diabetic Autonomic Neuropathy and Left Ventricular FunctionCompletedNCT05713396Phase 4
• Medicine-induced Cardiac Hemodialysis on COVID-19CompletedNCT05711810Phase 4
• Treatment Optimisation for Blood Pressure With Single-Pill Combinations in IndiaCompletedNCT05683301Phase 4
• Bioequivalence Study of Two Formulations of Tablets Ramipril 10 mg in Healthy Volunteers Under Fasting ConditionsCompletedNCT05438316Phase 1
• Intra-lesional ACE Inhibitor for Treatment of Hypertrophic ScarsWithdrawnNCT05259137Phase 2/3
• The Effect of Enalapril, Losartan or Not Antihypertensive on the Oxidative Status in Renal Transplant RecipientsCompletedNCT05232370Phase 2
• Bioequivalence Study of Two Formulations of Lisinopril Tablet 20 mg in Healthy Volunteers Under Fasting ConditionsCompletedNCT05061901Phase 1
• Lisinopril for Renal Protection in Postpartum Preeclamptic WomenWithdrawnNCT05016440Not applicable
• A Bioequivalence Study Between Capozide Versus ACE-Hemmer-ratiopharm in Healthy Adult Participants Under Fasting ConditionsWithdrawnNCT04964050Phase 1
• Bioequivalence Study Between Capoten Versus Captopril Reference Product in Healthy Adult Participants Under Fasting ConditionsWithdrawnNCT04878315Phase 1
• Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative NeoplasmsWithdrawnNCT04629651Phase 1/2
• Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and DyslipidemiaTerminatedNCT04591808Phase 3
• The COVID-RASi Trial (COVID-19)CompletedNCT04591210Phase 3
• Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast CancerCompletedNCT04588935Phase 2
• Ramipril in Pediatric Patients on HemodialysisCompletedNCT04582097Phase 2/3
• Blood Pressure Management in Stroke Following Endovascular TreatmentCompletedNCT04484350Phase 2
• The Standardized Management of Hypertension in Rural ShaanxiCompletedNCT04371874Not applicable
• African American Study of Kidney Disease and HypertensionCompletedNCT04364139Phase 3
• Efficacy of Captopril in Covid-19 Patients With Severe Acute Respiratory Syndrome (SARS) CoV-2 Pneumonia (CAPTOCOVID)Status unknownNCT04355429Phase 2
• Evaluation of the Efficacy of Captopril Versus Propranolol and Timolol as a Treatment of Infantile Capillary HemangiomaStatus unknownNCT04288700Phase 4
• Drug-drug-interaction Study of Ramipril, Amlodipine and AtorvastatinCompletedNCT04262765Phase 1
• Comparative Effects of Perindopril and Zofenopril on Blood Pressure Control and Oxidative Status Blacks Hypertensive Patients.CompletedNCT04254042Phase 4
• Explorative Study for Treating Persistent Developmental Stuttering With RamiprilActive, not recruitingNCT04173949Phase 3
• One Versus Twice Daily Administration of Multiple Cardiovascular Agents in Patients With Ischemic Heart DiseaseStatus unknownNCT04148820Phase 4
• Efficacy of ACE Inhibitors, MRAs and ACE Inhibitor/ MRA CombinationStatus unknownNCT04143412Phase 2
• Effect of Angiotensin Converting Enzyme and Sacubitril Valsartan in Patients After Bone Marrow TransplantationStatus unknownNCT04092309Not applicable
• Evaluation of the Safety and Effectiveness of Switching From Humira® to Imraldi® in FlandersCompletedNCT04045782Phase 4
• Moxonidine + Perindopril in Hypertensive Patients With Metabolic SyndromeStatus unknownNCT04023565Phase 4
• The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis PatientsStatus unknownNCT03991910Phase 3
• Ramipril, Endothelial Function and Endothelial Progenitor Cells in Patients With Systemic Lupus ErythematosusCompletedNCT03979976Phase 2/3
• Impact of Angiotensin Converting Enzyme Activity on Exercise Training SensitivityCompletedNCT03949075Not applicable
• Reversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor on Serum Uric Acid and Oxypurines Levels by Estrogen-progestin Therapy in Hypertensive Postmenopausal Women.CompletedNCT03921736Phase 4
• Short-term Effects of Perindopril-amlodipine Versus Perindopril-indapamide in Type 2 DiabetesCompletedNCT03747978Phase 4
• Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BATTerminatedNCT03686696Phase 4
• Enalapril Maleate on Arterial Stiffness in Rheumatoid Arthritis.CompletedNCT03667131Phase 2
• Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective DrugsCompletedNCT03660293Not applicable
• The Role and Intervention of TGF-β in Abdominal Radiation InjuryStatus unknownNCT03613506Phase 2
• H-Type Hypertension Precision Medicine TrialStatus unknownNCT03472508Phase 4
• Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsiaCompletedNCT03466333Phase 2
• A Pilot Study: Preventing Adverse Remodelling Following Pacemaker ImplantationStatus unknownNCT03422705Phase 2
• Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CADActive, not recruitingNCT03417388Phase 4
• A Drug-Drug Interaction Study Between Sotagliflozin and RamiprilCompletedNCT03414723Phase 1
• Effect of Morning Versus Evening Perindopril on Blood Pressure Control in People With Type 2 DiabetesCompletedNCT03393715Phase 4
• Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.WithdrawnNCT03392740Phase 4
• Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid LeukemiaCompletedNCT03389724Phase 3
• PROACT: Can we Prevent Chemotherapy-related Heart Damage in Patients With Breast Cancer and Lymphoma?CompletedNCT03265574Phase 3
• Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)Status unknownNCT03249285Phase 3
• Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)Status unknownNCT03201185Phase 4
• Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01)Status unknownNCT03195023Phase 4
• Matão Controlling Hypertension (MatCH Study): Rationale and DesignStatus unknownNCT03147092Early Phase 1
• A Study for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer PatientsActive, not recruitingNCT03127631Not applicable
• Comparing ARNI With ACE Inhibitor on Endothelial FunctionWithdrawnNCT03119623Phase 4
• An Open-label, Non-comparative Study to Document the Tolerability to Ramipril in Patients With at Least One High Risk for Developing a Major Cardiovascular EventCompletedNCT03099213Phase 4
• Prevention of Renal and Vascular Endstage Disease Intervention TrialCompletedNCT03073018Phase 3
• Genetic Determinants of ACEI Prodrug ActivationCompletedNCT03051282Phase 4
• Fixed Combination for Lipid and Blood Pressure ControlWithdrawnNCT03047538Phase 4
• Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes MellitusCompletedNCT03031834Phase 4
• Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2WithdrawnNCT03005184Phase 2
• Fixed vs Free Dose of ACEi/CCB Combination TherapyCompletedNCT02995954Phase 4
• Doxazosin and Ramipril in HypertensionCompletedNCT02901977Phase 4
• Expression and Function of the Renin-Angiotensin System in the EsophagusCompletedNCT02879721Early Phase 1
• Ramipril Treatment of Claudication: Oxidative Damage and Muscle FibrosisActive, not recruitingNCT02842424Phase 4
• Influence of Carboxypeptidase D (CPD) Gene on Body Weight and Fat Mass Reduction by Perindopril in Obese SubjectsTerminatedNCT02777489Phase 2
• The Precision Hypertension Care StudyCompletedNCT02774460Phase 4
• Comparison of Three Combination Therapies in Lowering Blood Pressure in Black AfricansCompletedNCT02742467Phase 4
• Perindopril vs Ramipril for Persistence in MAU Reduction StudyCompletedNCT02729441Phase 3
• Once-daily Fixed Combination of Three Antihypertensive DrugsStatus unknownNCT02710539Phase 4
• ACE-inhibitors in Extracapillary GlomerulonephritisStatus unknownNCT02682459Phase 2
• Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied DrugsCompletedNCT02641899Phase 1
• The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme InhibitorsStatus unknownNCT02623036Phase 1
• The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and TreatmentCompletedNCT02575092Phase 2/3
• The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in ChildrenStatus unknownNCT02532790Phase 2
• Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular DysfunctionCompletedNCT02525081Phase 4
• REducing Blood Pressure Variability in Essential Hypertension With RAmipril vErsus Nifedipine GITS TrialCompletedNCT02499822Phase 4
• Evaluation of Periop Biochemical Stress Factors in Craniotomy Neurosurgical Procedure With Respect to Preop HypertensionCompletedNCT02441842Phase 4
• Myocardial Fibrosis Progression in Duchenne and Becker Muscular Dystrophy - ACE Inhibitor Therapy TrialCompletedNCT02432885Phase 3
• Drug to Prevent Pneumonia in the Tube FedTerminatedNCT02358642Phase 4
• DOXAZOSIN FOR PTSDCompletedNCT02308202Phase 1
• The Intracerebral Hemorrhage Acutely Decreasing Arterial Pressure Trial IITerminatedNCT02281838Phase 2
• Relative Bioavailability Study With Enalapril in Healthy VolunteersStatus unknownNCT02252692Phase 1
• Cardiotoxicity Prevention in Breast Cancer Patients Treated With Anthracyclines and/or TrastuzumabStatus unknownNCT02236806Phase 3
• Modulation of Heme Oxygenase 1 by Nizatidine and Lisinopril in Healthy SubjectsCompletedNCT02232308Phase 1
• Treatment of Hypertension in Tibetan Adult PopulationStatus unknownNCT02217852Phase 4
• Steady State Pharmacokinetics of Telmisartan, Ramipril or the Combination Following Repeated Oral Doses to Healthy Male and Female VolunteersCompletedNCT02215005Phase 1
• Bioequivalence of Telmisartan/g Ramipril Fixed Dose Combination Compared With the Monocomponents Telmisartan and Ramipril (Two Different Formulations) Given Concomitantly to Healthy Male and Female VolunteersCompletedNCT02214992Phase 1
• Bioequivalence of Telmisartan / Ramipril Fixed Dose Combination Compared With the Monocomponents Given Concomitantly to Healthy Male and Female VolunteersCompletedNCT02214979Phase 1
• Treatment of HYpertension: Morning Versus EveningStatus unknownNCT02214498Phase 4
• Perindopril and Telmisartan for the Treatment of Nonalcoholic Fatty Liver DiseaseStatus unknownNCT02213224Phase 4
• Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary HypertensionCompletedNCT02184858Phase 4
• Metabolism of Methylphenidate and Enalapril Based on CES1 GenotypeCompletedNCT02135263Phase 4
• Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCADTerminatedNCT02008786Phase 4
• Non-invasive Haemodynamic Assessment in HypertensionCompletedNCT01996085Not applicable

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