Analgesics, Opioid: all 2,341 studies that test it
Page 1 of 24. Open to participants first (249), then studies with results posted, then the rest; newest registration first within each.
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationRecruitingNCT07877519Not applicable
- Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) TabletsRecruitingNCT07868419Phase 3
- Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck CancersRecruitingNCT07857655Phase 4
- ITM vs ITM+Clonidine for Lumbar FusionsNot yet recruitingNCT07846657Phase 3
- Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis ReleaseRecruitingNCT07840183Phase 4
- Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia RepairNot yet recruitingNCT07837492Phase 4
- REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential MonitoringNot yet recruitingNCT07835295Phase 4
- Adaptive Platform Trial for Pain Management in Sickle Cell Vaso-Occlusive CrisisNot yet recruitingNCT07826988Phase 4
- Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)RecruitingNCT07824817Phase 4
- Post-Vasectomy Pain StudyRecruitingNCT07824258Phase 1
- Abuse Potential of Gabapentin Taken Orally Concomitantly With Oxycodone Hydrochloride in Healthy, Non-Drug-Dependent, Recreational Opioid UsersRecruitingNCT07813026Phase 4
- Ultrasound-Guided Posterior Quadratus Lumborum Block With Bupivacaine and Dexmedetomidine Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean DeliveryNot yet recruitingNCT07807592Phase 4
- PENG Block Versus Intrathecal Morphine for Early Postoperative Recovery After Total Hip ArthroplastyNot yet recruitingNCT07803133Not applicable
- Remifentanil vs Fentanyl in Children 7-12 After Urologic Surgery: Emergence Delirium and Recovery QualityNot yet recruitingNCT07800845Phase 4
- Buprenorphine for the Management of Pain in Children With Sickle Cell DiseaseNot yet recruitingNCT07799571Phase 1
- Adductor Canal Block Versus Parasartorial Compartment Block for Pain Relief and Recovery After Arthroscopic Knee SurgeryNot yet recruitingNCT07790393Not applicable
- BUprenorphine Versus Morphine for Postcesarean Analgesia (BUMP)RecruitingNCT07786012Phase 4
- 90% Effective Infusion Time of Sufentanil to Prevent Induction Cough: A Biased Coin Sequential StudyNot yet recruitingNCT07778953Not applicable
- How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play?RecruitingNCT07778511Not applicable
- Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation SurgeriesRecruitingNCT07777627Not applicable
- Subcutaneous Methadone for Cesarean Analgesia: a Non Inferiority Study Using QoR-10Not yet recruitingNCT07777029Not applicable
- Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery PatientsNot yet recruitingNCT07768150Not applicable
- Afentanil and Remifentanil for Anesthesia Quality and RecoveryNot yet recruitingNCT07761312Phase 4
- A Study to Evaluate the Drug-Drug Interaction Between KL0011034 Injection and Alfentanil Hydrochloride Injection in Participants With Moderate-to-Severe Non-Cancer Chronic PainNot yet recruitingNCT07751094Phase 1
- Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric GastroscopyNot yet recruitingNCT07748884Phase 4
- Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.Not yet recruitingNCT07736352Not applicable
- Analgesia With Transdermal Buprenorphine Patch in Adults Undergoing Video-Assisted Thoracoscopic SurgeryRecruitingNCT07733128Not applicable
- Efficacy of Adding Intrathecal Morphine to Erector Spinae Plane Block for Postoperative Analgesia After Midline LaparotomyRecruitingNCT07720739Not applicable
- Quadro-Iliac Plane Block for Pain Control After Posterior Spinal Instrumentation SurgeryNot yet recruitingNCT07711522Early Phase 1
- The ED95 of Ciprofol for Laryngeal Mask Airway Insertion With Fentanyl in Children: A Biased-Coin Dose-Finding TrialRecruitingNCT07697404Phase 4
- REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.Not yet recruitingNCT07695220Not applicable
- The Effect of Nalbuphine Extended-Release (NAL ER) on Cough in Participants With Refractory Chronic Cough (RCC)RecruitingNCT07671924Phase 2
- Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine Extended-Release (NAL ER) TabletsRecruitingNCT07671911Phase 3
- Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic CholecystectomyNot yet recruitingNCT07670052Phase 4
- Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil EmbolizationNot yet recruitingNCT07660861Not applicable
- Remifentanil Monotherapy vs. Remifentanil-Nicardipine for Controlled Hypotension in Otolaryngological SurgeryNot yet recruitingNCT07659496Not applicable
- Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative PainNot yet recruitingNCT07657468Phase 2
- Effect of Liposomal Bupivacaine TAPB Combined With Oxycodone PCIA on Postoperative Gastrointestinal Recovery in Patients Undergoing Major Abdominal SurgeryRecruitingNCT07651722Not applicable
- The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .RecruitingNCT07640516Not applicable
- Sedation Methods in Percutaneous Transhepatic Biliary Drainage: Procedure Quality and RecoveryRecruitingNCT07640243Not applicable
- Intrathecal Analgesia in Laparoscopic Nissen Fundoplication.Enrolling by invitationNCT07629323Not applicable
- Evaluation of the Efficacy of Sublingual Sufentanil (Prescribed as Rescue Analgesia for Acute Postoperative Pain) on the Quality of Health Recovery After Surgery: a Randomized, Controlled, Multicenter, Open-label Trial Against an Active Comparator (SUBLIME)Not yet recruitingNCT07624006Phase 4
- Dose-Response Interaction of Metoprolol and Sufentanil for Attenuating Hemodynamic Responses in Tracheal IntubationNot yet recruitingNCT07597564Phase 4
- A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019)RecruitingNCT07595263Phase 1
- Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)Not yet recruitingNCT07565870Phase 3
- Patient Quality of Recovery After TAVR With Different Sedation RegimensRecruitingNCT07556523Phase 4
- Methadone Rapid RestartNot yet recruitingNCT07546396Phase 4
- Methadone for Post-operative Spine SurgeryRecruitingNCT07517679Phase 4
- Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer PainRecruitingNCT07489625Early Phase 1
- Methadone in the Management of Post-Operative Pain in Total Knee ReplacementRecruitingNCT07485803Phase 4
- A Bundled Intervention to End Opioid OverdosesRecruitingNCT07485335Phase 4
- Comparing Outpatient Treatment Retention Among Individuals Using Fentanyl Randomized to Low-dose and Direct-to-inject Buprenorphine InitiationNot yet recruitingNCT07469501Phase 4
- Prospective IR-led Sedation FeasibilityRecruitingNCT07443254Phase 1/2
- Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active LaborRecruitingNCT07440069Phase 4
- Symptom-Inhibited Naloxone Induction (SINI) for Buprenorphine Initiation: A Feasibility TrialRecruitingNCT07439549Phase 4
- Effect of Nalbuphine Versus Fentanyl on Hemdoynamic Effects of LaryngoscopyRecruitingNCT07435337Phase 4
- Examining Analgesic Synergy and Efficacy in Trauma CareNot yet recruitingNCT07435077Phase 4
- Comparison of the Efficacy and Safety of Intravenous Buprenorphine Administered Via PCA System Versus Oxycodone in the Management of Postoperative Pain After Video-Assisted Thoracoscopic SurgeryRecruitingNCT07434427Phase 4
- Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency DepartmentRecruitingNCT07430345Phase 1/2
- Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection PainNot yet recruitingNCT07422558Not applicable
- Opioid-Free Anesthesia Versus Opioid Based Anesthesia For Adolescent Idiopathic ScoliosisRecruitingNCT07389096Phase 4
- Intrathecal Versus Epidural Morphine for Post-Cesarean AnalgesiaRecruitingNCT07386353Phase 4
- Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean SectionNot yet recruitingNCT07377630Phase 4
- Inhalational Agents Versus Dexmedetomidine for Maintenance of General AnesthesiaRecruitingNCT07363681Not applicable
- Clinical Outcomes of Sedation in Cataract Surgery Performed Under Topical AnesthesiaNot yet recruitingNCT07347886Not applicable
- Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft SurgeryRecruitingNCT07340008Not applicable
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain ServiceNot yet recruitingNCT07296770Phase 3
- A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic CoughNot yet recruitingNCT07288528Phase 4
- Ultrasound-Guided Infraclvicular Block Using Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Upper Limb Orthopedic SurgeryNot yet recruitingNCT07279727Phase 1
- Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower ExtremityRecruitingNCT07276867Not applicable
- Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly PatientsRecruitingNCT07271849Phase 4
- Combined Intravenous Tramadol and Paracetamol Versus Intramuscular Pethidine for Pain Relief During the First Stage of Labor. Compare the Efficacy and Adverse EffectsRecruitingNCT07264309Not applicable
- Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency LaparotomyRecruitingNCT07262242Not applicable
- Intrathecal Morphine Versus Trocar-Site and Intraperitoneal Bupivacaine for Quality of Recovery After Laparoscopic HysterectomyRecruitingNCT07232108Not applicable
- Methadone in THA for Post-op Pain and Opioid ReductionRecruitingNCT07227064Phase 3
- Methadone in TKA for Post-op Pain and Opioid ReductionRecruitingNCT07226076Phase 3
- Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility StudyRecruitingNCT07222072Phase 4
- Hemodynamic and Cardiac Effects of Dexmedetomidine Versus Fentanyl by Intravenous Infusion as Adjuncts to General Anesthesia in Patients Undergoing Major Abdominal Cancer Surgeries.Not yet recruitingNCT07214714Phase 4
- EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and SedativesRecruitingNCT07211828Not applicable
- Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic CholecystectomyNot yet recruitingNCT07203794Not applicable
- Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm NeonatesRecruitingNCT07190625Early Phase 1
- Fentanyl vs. Remifentanil in Laparoscopic Cholecystectomy: Effects on Bowel Function and PainRecruitingNCT07182097Not applicable
- Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled HypotensionRecruitingNCT07181564Not applicable
- Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile Pharmacy ClinicRecruitingNCT07176351Phase 4
- Study Comparing Atomizerd Midazolam & Fentanyl and Dexmedomidine for Procedural Sedation in Adult and Pediatric Patient (2 to 60 Years Old)Not yet recruitingNCT07166666Not applicable
- Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip ArthroplastyEnrolling by invitationNCT07153003Phase 4
- Fentanyl Versus Ketorolac as an Adjuvant to Peribulbar Block for Anterior Segment SurgeriesRecruitingNCT07141589Not applicable
- Pain Control Alternatives in Pediatric Patients With Distal Radius FracturesRecruitingNCT07120763Phase 3
- Study of The Analgesic Profile of Two Adjuvants Added to Low Dose Hyperbaric Bupivacaine Versus One Adjuvant in Patients Undergoing Anal Surgery Using Spinal AnesthesiaNot yet recruitingNCT07114263Not applicable
- Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm InfantsNot yet recruitingNCT07112430Phase 1/2
- Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer PatientRecruitingNCT07110051Not applicable
- Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled TrialNot yet recruitingNCT07094802Phase 4
- The Effect-site Concentration of Remifentanil Blunting Endotracheal Intubation Responses During Anesthesia Induction With Lidocaine or Sufentanil Combined With Etomidate: A Randomized Controlled StudyRecruitingNCT07089173Not applicable
- Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and FentanylRecruitingNCT07078201Phase 4
- Ropivacaine and Fentanyl for Labor Epidural InitiationRecruitingNCT07076368Phase 3
- Effects of Intraarticular Tramadol and Tramadol-Dexamethasone on Postoperative Pain After Knee ArthroscopyNot yet recruitingNCT07064993Phase 4
- Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing ChildrenNot yet recruitingNCT07062601Not applicable
- Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean SectionRecruitingNCT07054775Phase 4
- Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIPEnrolling by invitationNCT07036237Not applicable
- Stellate Ganglion Morphine Infiltration on Myocardial I/R InjuryRecruitingNCT07023679Not applicable