Alkylating agents: all 3,295 studies that test it
Page 15 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.
- Cyclophosphamide, Fludarabine, and High-Dose Interleukin-2 in Treating Patients With Metastatic MelanomaCompletedNCT00085423Phase 2Results posted
- Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00085254Phase 1/2Results posted
- Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid TumorCompletedNCT00085202Phase 3Results posted
- Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell TumorCompletedNCT00085098Phase 3Results posted
- Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RTCompletedNCT00084838Phase 2Results posted
- DTPACE Followed by Tandem Transplant With Melphalan (MEL) 200 Versus MEL/Dexamethasone/Thalidomide (DT) Platinol/Adriamycin/Etoposide (PACE) Hybrid and DTPACE ConsolidationCompletedNCT00083915Phase 3Results posted
- Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung CancerCompletedNCT00080938Phase 2Results posted
- Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade GliomaCompletedNCT00077207Not applicableResults posted
- Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus ErythematosusCompletedNCT00076752Phase 2Results posted
- 2nd Autologous Stem Cell Transplant in Patients With Persistent/Recurrent (AL) AmyloidosisTerminatedNCT00075608Phase 2Results posted
- Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk RhabdomyosarcomaCompletedNCT00075582Phase 3Results posted
- Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLLCompletedNCT00074282Phase 2Results posted
- Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast CancerTerminatedNCT00074269Phase 2Results posted
- Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's LymphomaCompletedNCT00073918Phase 2Results posted
- Bevacizumab and Low-Dose Cyclophosphamide in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal CancerCompletedNCT00072566Phase 2Results posted
- Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood FibrosarcomaTerminatedNCT00072280Phase 2Results posted
- S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast CancerActive, not recruitingNCT00070564Phase 3Results posted
- Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete RemissionCompletedNCT00070135Phase 2Results posted
- S0313 Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Radiation Therapy Followed By Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Stage I or Stage II Non-Hodgkin's LymphomaCompletedNCT00070018Phase 2Results posted
- Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System LymphomaCompletedNCT00068250Phase 1/2Results posted
- Randomized Double Cord Blood Transplant StudyCompletedNCT00067002Phase 2Results posted
- Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ TransplantationCompletedNCT00066469Phase 2Results posted
- S0115, High-Dose Melphalan and Autologous Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Primary Systemic AmyloidosisCompletedNCT00064337Phase 2Results posted
- Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With MedulloblastomaCompletedNCT00058370Not applicableResults posted
- Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple MyelomaCompletedNCT00054353Phase 1/2Results posted
- Donor Stem Cell Transplant in Treating Patients With Hematologic CancerCompletedNCT00054327Phase 2Results posted
- NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/DisordersCompletedNCT00053989Phase 2Results posted
- Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic CancerCompletedNCT00049504Phase 2Results posted
- Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell TumorsCompletedNCT00047320Phase 2Results posted
- Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric SarcomasCompletedNCT00043979Phase 2Results posted
- Four Versus Six Cycles of Cyclophosphamide/Doxorubicin or Paclitaxel in Adjuvant Breast CancerCompletedNCT00041119Phase 3Results posted
- S0204 Thalidomide, Chemotherapy, and Peripheral Stem Cell Transplant in Treating Patients With Multiple MyelomaCompletedNCT00040937Phase 2Results posted
- Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant DiseasesCompletedNCT00038857Phase 2Results posted
- Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed MedulloblastomaTerminatedNCT00031590Phase 2Results posted
- Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for EpendymomaCompletedNCT00027846Phase 2Results posted
- Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic CancerCompletedNCT00027560Phase 2Results posted
- Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain MetastasesCompletedNCT00026494Phase 1/2Results posted
- Low-dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-negative Early Breast CancerCompletedNCT00022516Phase 3Results posted
- Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast CancerCompletedNCT00021255Phase 3Results posted
- Chemotherapy Followed by Peripheral Stem Cell Transplantation Plus Biological Therapy in Treating Women With Stage IV Breast CancerTerminatedNCT00020722Phase 2Results posted
- Permeability Factor in Focal Segmental GlomerulosclerosisCompletedNCT00007475Phase 1/2Results posted
- Melphalan, Peripheral Stem Cell Transplantation, and Interleukin-2 Followed by Interferon Alfa in Treating Patients With Advanced Multiple MyelomaCompletedNCT00006244Phase 2Results posted
- Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple MyelomaCompletedNCT00006184Phase 2Results posted
- Multimodality Treatment for Women With Stage II, Stage III, or Stage IV Breast CancerCompletedNCT00006110Phase 2Results posted
- Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory LymphomaCompletedNCT00005803Phase 1/2Results posted
- Scleroderma Lung DiseaseCompletedNCT00004563Phase 3Results posted
- Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed GliomasCompletedNCT00004259Phase 3Results posted
- Combination Chemo, Peripheral Stem Cell Transplant, Biological Therapy, Pamidronate and Thalidomide for Multiple MyelomaCompletedNCT00004088Phase 2Results posted
- Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic LeukemiaTerminatedNCT00003910Phase 2Results posted
- Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the LiverCompletedNCT00003907Phase 2Results posted
- Busulfan and Etoposide Followed by Peripheral Blood Stem Cell Transplant and Low-Dose Aldesleukin in Treating Patients With Acute Myeloid LeukemiaCompletedNCT00003875Phase 2Results posted
- Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic CancerCompletedNCT00003816Phase 2/3Results posted
- Fludarabine, Cyclophosphamide, and Rituximab in Treating Patients Who Have Chronic Lymphocytic LeukemiaCompletedNCT00003659Phase 2Results posted
- Chemotherapy Plus Radiation Therapy in Treating Patients With Refractory or Relapsed Hodgkin's LymphomaCompletedNCT00003631Phase 2Results posted
- Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's LymphomaCompletedNCT00003389Phase 3Results posted
- Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic CancerCompletedNCT00003270Phase 2Results posted
- Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast CancerCompletedNCT00003199Phase 2Results posted
- Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast CancerCompletedNCT00003042Phase 2Results posted
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell CancerCompletedNCT00002931Phase 2Results posted
- Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With SarcomaCompletedNCT00002601Phase 2Results posted
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell TumorsCompletedNCT00002558Phase 1/2Results posted
- Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic MelanomaCompletedNCT00001832Phase 2Results posted
- Bladder Preservation or Cystectomy for MIBCActive, not recruitingNCT07821177Early Phase 1
- Adjuvant Therapy of Skin Melanoma With Alpha Interferon and NaderinCompletedNCT07671495Phase 2
- SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade GliomasCompletedNCT07635173Phase 1
- Efficacy of Low-dose PT-Cy for Prevention of GVHD in Ambulatory Allogeneic HSCTCompletedNCT07319000Phase 2
- An Open-label Study of GC012F in Rheumatoid Arthritis.WithdrawnNCT07315503Early Phase 1
- Safety and Efficacy of FT14 Conditioning for Allogeneic HSCT in Acute Myeloid LeukemiaActive, not recruitingNCT07232953Phase 2
- UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune DiseasesActive, not recruitingNCT07155369Not applicable
- Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular CarcinomaSuspendedNCT06968195Phase 1
- A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)SuspendedNCT06959537Phase 1
- Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic LeukemiaSuspendedNCT06738368Phase 2
- UF-KURE-BCMA CAR-T Cells in Patients With Relapsed or Refractory Multiple MyelomaWithdrawnNCT06698744Phase 1
- A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal MalignanciesWithdrawnNCT06690281Phase 2
- STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and MelanomaWithdrawnNCT06626256Phase 1
- Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyCompletedNCT06625047Phase 4
- ALPP CAR-T Cells for ALPP-Positive Advanced Solid TumorsCompletedNCT06556108Phase 1/2
- Safety and Efficacy of Anti-CD20/CD30 CAR-T Cells in Subjects with Relapsed/Refractory LymphomaStatus unknownNCT06532643Early Phase 1
- Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant GliomaActive, not recruitingNCT06478212Phase 1/2
- Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic CancerCompletedNCT06464965Phase 1
- BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder CancerActive, not recruitingNCT06462001Phase 3
- Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic LeukemiaSuspendedNCT06447987Phase 1
- Evaluate Safety and Efficacy of High-dose Melphalan HCL for Injection in MM Patients With Auto-HSC TransplantationCompletedNCT06425276Phase 4
- TIP Regimen Combined With Toripalimab Neoadjuvant Therapy for Locally Advanced Penile CancerCompletedNCT06415318Phase 2
- Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic CancerActive, not recruitingNCT06253520Phase 1
- Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral StrictureCompletedNCT06232005Phase 2/3
- HCT With PTCy in Higher-risk MDSActive, not recruitingNCT06098313Phase 2
- Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM PatientsCompletedNCT06095375Phase 1
- Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate CancerWithdrawnNCT06094842Phase 1
- To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCLActive, not recruitingNCT06072131Phase 3
- Optimizing Lymphodepletion to Improve Outcomes in Patients Receiving Cell Therapy With KymriahWithdrawnNCT06003179Phase 1
- HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD ProphylaxisActive, not recruitingNCT06001385Phase 2
- CART-BCMA/CS1 in Treating Patients With Relapsed or Refractory Multiple MyelomaWithdrawnNCT05950113Phase 1
- Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic CancerActive, not recruitingNCT05922930Phase 1/2
- PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin LymphomaActive, not recruitingNCT05922904Phase 2
- REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity MitigationActive, not recruitingNCT05902533Phase 2/3
- High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHDWithdrawnNCT05895201Phase 1/2
- The Efficacy and Safety of Temozolomide in Patients With MPPGLCompletedNCT05858177Phase 2
- Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue SarcomaTerminatedNCT05813327Phase 1
- A Exploratory Trial of WTX221 in Refractory Gout PatientsStatus unknownNCT05800041Early Phase 1