Alkylating agents: all 3,295 studies that test it
Page 16 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.
- R-MINE+X in Patients With Relapsed/Refractory Diffuse Large B-cell LymphomaStatus unknownNCT05784987Not applicable
- Post-transplantation Cyclophosphamide in Haploidentical Stem Cell Allografts Dose Reduction: 50 mg/kg vs 25 mg/kgStatus unknownNCT05780554Not applicable
- R-CMOP in Patients With Primary Diffuse Large B-cell LymphomaStatus unknownNCT05777369Not applicable
- CAR- PRISM (PRecision Intervention Smoldering Myeloma)Active, not recruitingNCT05767359Phase 2
- Broccoli Seed Extract and Skin HealthCompletedNCT05745636Not applicable
- CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First RemissionActive, not recruitingNCT05707273Phase 1
- Neoadjuvant Chemoimmunotherapy in Recurrent GlioblastomaStatus unknownNCT05700955Phase 1
- LITT Combined With Early Use of Temozolomide for Recurrent GlioblastomasStatus unknownNCT05663125Phase 1/2
- Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBCActive, not recruitingNCT05645380Phase 2
- Comparison Between Topical Mitomycin C and CyclosporineCompletedNCT05627947Phase 1
- De-escalated Cyclophosphamide (PTCy) and Ruxolitinib for Graft-versus-Host Disease (GVHD) ProphylaxisActive, not recruitingNCT05622318Phase 2
- Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHDActive, not recruitingNCT05621759Phase 2
- A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone SarcomaActive, not recruitingNCT05621668Phase 1
- A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)TerminatedNCT05600426Phase 3
- Safety and Efficacy of TRPP Therapy in Glioblastoma MultiformeStatus unknownNCT05589961Early Phase 1
- A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)Active, not recruitingNCT05578976Phase 3
- Anti-BCMA Chimeric Antigen Receptor T Cells for Relapsed or Refractory Multiple MyelomaActive, not recruitingNCT05577000Phase 1
- A Study of Tazemetostat With Rituximab and Abbreviated Bendamustine in the Frontline Treatment of High Tumor Burden Follicular LymphomaActive, not recruitingNCT05551936Phase 1/2
- Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan PharmacokineticsCompletedNCT05534620Phase 1
- Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical TrialStatus unknownNCT05532111Not applicable
- Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid TumorsWithdrawnNCT05531708Phase 1
- High-dose Chemotherapy+G-CSF in Peripheral Blood Stem Cell Mobilization in Patients With Multiple MyelomaCompletedNCT05517213Not applicable
- Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid MalignanciesWithdrawnNCT05513612Phase 1
- Optimal Conditioning Regimen for Autologous Transplantation of Relapsing Remitting Multiple SclerosisWithdrawnNCT05482542Not applicable
- Cyclophosphamide and Dexamethasone for the Treatment of Metastatic Castration Resistant Prostate CancerActive, not recruitingNCT05479578Phase 1
- Surgical Pembro +/- Olaparib w TMZ for rGBMActive, not recruitingNCT05463848Phase 2
- Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingNCT05457556Phase 3
- G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCTStatus unknownNCT05453552Phase 2/3
- Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic LeukemiaActive, not recruitingNCT05453500Phase 2
- Clinical Study of Safety and Tolerability of Melphalan Hydrochloride for R/R MMStatus unknownNCT05438394Phase 1
- Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid TumorsTerminatedNCT05429502Phase 1
- Golden Halo, Static Magnetic and Electric Field Device, in Recurrent GlioblastomaWithdrawnNCT05410301Not applicable
- Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and AboveActive, not recruitingNCT05404945Phase 2
- ......SMARTEST Trial......CompletedNCT05380713Phase 2
- Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell TransplantsActive, not recruitingNCT05364762Phase 2
- A Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Glofitamab in Combination With Rituximab Plus Ifosfamide, Carboplatin Etoposide Phosphate in Participants With Relapsed/Refractory Transplant or CAR-T Therapy Eligible Diffuse B-Cell LymphomaCompletedNCT05364424Phase 1
- Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First ProgressionWithdrawnNCT05304663Phase 1
- Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis FungoidesCompletedNCT05303480Not applicable
- Zanubrutinib Followed Zanubrutinib Plus FCR / BR in Newly Diagnosed Symptomatic CLL/SLLStatus unknownNCT05287984Phase 2
- Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors, the ComPareNET TrialActive, not recruitingNCT05247905Phase 2
- Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian CancerTerminatedNCT05243524Phase 2
- Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell LymphomaWithdrawnNCT05228249Phase 1
- Temozolomide for Injection Combined With Epirubicin in First-line Treatment of LeiomyosarcomaStatus unknownNCT05204524Not applicable
- A Phase II Study of Zanubrutinib, Lenalidomide Plus R-CHOP as the First-line Treatment for Diffused Large B-cell LymphomaStatus unknownNCT05200312Phase 2
- Personalized DC Vaccines in Non Small Cell Lung CancerActive, not recruitingNCT05195619Phase 1
- Comparison of PT-Cy at a Dose of 25 mg/kg/Day and PT-Cy at a Dose of 50 mg/kg/Day in GVHD ProphylaxisStatus unknownNCT05158608Phase 3
- GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATGActive, not recruitingNCT05153226Phase 3
- A Phase 2 Study of Isatuximab in Combination With Bortezomib, Cyclophosphamide and Dexamethasone Followed by Isatuximab and Lenalidomide Maintenance in Newly Diagnosed Patients With Multiple Myeloma and Severe Renal ImpairmentStatus unknownNCT05147493Phase 2
- 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingNCT05139004Phase 1
- Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated GlioblastomaActive, not recruitingNCT05095376Phase 3
- Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted GraftActive, not recruitingNCT05088356Phase 1
- Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell LymphomaActive, not recruitingNCT05052528Phase 1
- Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14.Status unknownNCT05049473Phase 2
- Temozolomide and Irinotecan in Patients With MGMT Silenced Colorectal Cancer After Adjuvant ChemotherapyStatus unknownNCT05031975Phase 2
- Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.CompletedNCT05027386Phase 1/2
- Guiding Instillation in Non Muscle-invasive Bladder Cancer Based on Drug Screens in Patient Derived OrganoidsActive, not recruitingNCT05024734Phase 2
- An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular MelanomaActive, not recruitingNCT05022901Phase 3
- TriPRIL CAR T Cells in Multiple MyelomaActive, not recruitingNCT05020444Phase 1
- Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or GliosarcomaWithdrawnNCT05017610Early Phase 1
- Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple MyelomaWithdrawnNCT05013437Early Phase 1
- Anti-BCMA CAR-NK Cell Therapy for the Relapsed or Refractory Multiple MyelomaStatus unknownNCT05008536Early Phase 1
- Observation of the Efficacy of BAd Regimen in the Treatment of Relapsed and Refractory Multiple MyelomaStatus unknownNCT05006469Phase 3
- Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid LeukemiaTerminatedNCT04994808Phase 2
- A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk RhabdomyosarcomaActive, not recruitingNCT04994132Phase 3
- Temozolomide + Nivolumab in MGMT Methylated Oesophagogastric CancerCompletedNCT04984733Phase 2
- PET-Adapted Low-Dose Nivolumab With NICE-40 for Relapsed/Refractory Classical Hodgkin LymphomaCompletedNCT04981899Phase 2
- A Study to Evaluate the Tolerability, Safety, Pharmacokinetics, and Antitumor Activity of Loncastuximab Tesirine in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated Diffuse Large B-cell Lymphoma (LOTIS-8)WithdrawnNCT04974996Phase 1
- Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)CompletedNCT04965597Phase 2
- A Study of N9 Chemotherapy in Children With NeuroblastomaActive, not recruitingNCT04947501Early Phase 1
- Post-transplantation Benadamustine and Cyclophosphamide in Patients With Refractory Myeloid MalignanciesCompletedNCT04943757Phase 2
- Isatuximab and Bendamustine in Systemic Light Chain AmyloidosisWithdrawnNCT04943302Phase 2
- Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)CompletedNCT04942730Phase 2
- Pharmacokinetic Study of Melphalan in Pediatric Hematopoietic Stem Cell TransplantationStatus unknownNCT04937634Phase 1
- A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian TumorsActive, not recruitingNCT04931342Phase 2
- Therapy Adapted for High Risk and Low Risk HIV-Associated Anal CancerActive, not recruitingNCT04929028Phase 2
- HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation CyclophosphamideActive, not recruitingNCT04904588Phase 2
- GFRα4 CAR T Cells in MTC PatientsActive, not recruitingNCT04877613Phase 1
- A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow TransplantActive, not recruitingNCT04872595Phase 2
- Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical StudyStatus unknownNCT04842526Phase 2
- Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of GlioblastomaStatus unknownNCT04829097Phase 3
- Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal AdenocarcinomaTerminatedNCT04809766Phase 1
- A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL)TerminatedNCT04790903Phase 1
- Chlorpheniramine Maleate Nasal Spray for Chronic RhinitisWithdrawnNCT04790487Phase 2/3
- A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue SarcomaTerminatedNCT04780464Phase 3
- Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe HemoglobinopathiesWithdrawnNCT04776850Early Phase 1
- A Prospective Study of Cyclophosphamide Treatment for Idiopathic Retroperitoneal FibrosisStatus unknownNCT04762810Phase 4
- The Efficacy and Safety of Pomalidomide and Bendamustine With Dexamethasone in Relapsed or Refractory Multiple MyelomaStatus unknownNCT04762745Phase 1/2
- Primary Chemotherapy by BCNU-TMZ Combination in Newly Diagnosed Anaplastic Oligodendrocytic Tumors: Phase II Trial With Translational Molecular AnalysisCompletedNCT04755023Phase 2
- The Neoadjuvant Combined Hormone Therapy in Premenopausal Women With Locally Advanced ER+/HER2- Breast CancerStatus unknownNCT04753177Phase 2/3
- 131I-Omburtamab, in Recurrent Medulloblastoma and EpendymomaActive, not recruitingNCT04743661Phase 2
- A Phase 1 Study of ADI-001 in B Cell MalignanciesTerminatedNCT04735471Phase 1
- Transarterial Chemoembolization for the Treatment of Uveal Melanoma With Liver MetastasesActive, not recruitingNCT04728633Phase 2
- CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine LeiomyosarcomaCompletedNCT04727242Phase 2
- Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Acute B Lymphocytic LeukemiaStatus unknownNCT04714593Phase 1/2
- A Phase 2 Trial for Patients With Metastatic Solid CancerActive, not recruitingNCT04713371Phase 2
- Novel BCMA-targeted CAR-T Cell Therapy for Multiple MyelomaStatus unknownNCT04706936Phase 1
- Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHLActive, not recruitingNCT04697940Phase 1/2
- CD123 Redirected T Cells for AML in Pediatric SubjectsTerminatedNCT04678336Phase 1
- CPD-DARA in Patients With Relapsed/Refractory Multiple Myeloma.Active, not recruitingNCT04667663Phase 1
- Cabozantinib With Topotecan-CyclophosphamideCompletedNCT04661852Phase 1