Typhoid Fever clinical trials
The registry lists 76 studies for Typhoid Fever across more than 10 countries. 11 are recruiting or about to start. 66 of them are mainly about Typhoid Fever (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
International Vaccine Institute (11) · University of Oxford (6) · Novartis (6) · International Centre for Diarrhoeal Disease Research, Bangladesh (5) · University of Maryland, Baltimore (5) · GlaxoSmithKline (3) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (3) · Oxford University Clinical Research Unit, Vietnam (3)
What is being tested here
Drugs under test in Typhoid Fever studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Jan 2027COMPARISON OF SINGLE VERSUS COMBINATION DRUG THERAPY IN EXTENSIVELY DRUG RESISTANT SALMONELLA TYPHI IN TERMS OF TIME TO DEFERVESCENCE · Iqra Asghar Ali
- Jan 2027Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever · Indus Hospital and Health Network
- Aug 2027CVD 37000: Immunity and Microbiome Studies at Intestinal and Systemic Sites in Ty21a Vaccinated Adults · University of Maryland, Baltimore
- Sep 2027Curcumin Extract Added to Ciprofloxacin for Typhoid Carriers Among Food Handlers of the Free Nutritious Meal Program · Universitas Sebelas Maret
Who these studies take
Of the 6 Typhoid Fever studies recruiting now, 2 (33%) set no upper age limit and 4 (67%) stop at 75 or younger. 4 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (83%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (50%) | 3 (50%) |
| 18 | 4 (67%) | 4 (67%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 4 (67%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 4 (67%) | 4 (67%) |
| 75 | 2 (33%) | 2 (33%) |
| 85 | 2 (33%) | 2 (33%) |
Across all 76 studies, recruiting or not: 84% stop at 75 or younger and 82% at 65; 59% take children; 1% are for women only and 0% for men only; 75% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 76. Browse all 76 → or search them.
- Curcumin Extract Added to Ciprofloxacin for Typhoid Carriers Among Food Handlers of the Free Nutritious Meal ProgramNot yet recruitingNCT07908030Phase 21 country
- CVD 38000: Study of Responses to Vaccination With Typhoid and/or CholeraRecruitingNCT03705585Phase 41 country
- COMPARISON OF SINGLE VERSUS COMBINATION DRUG THERAPY IN EXTENSIVELY DRUG RESISTANT SALMONELLA TYPHI IN TERMS OF TIME TO DEFERVESCENCENot yet recruitingNCT07641348Not applicable1 country
- Meropenem vs Azithromycin Efficacy in Case XDR Enteric FeverRecruitingNCT07314281Phase 41 country
- A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella Disease and Typhoid Fever in InfantsRecruitingNCT07286370Phase 21 country
- Blood Donor CVD 5000RecruitingNCT03971669Phase 41 country
- Long-Term Protection of Vi Antibodies Induced by Bio TCV in Indonesian Population Compared to PQed TCVNot yet recruitingNCT069214601 country
- Transcriptomic Responses for the Identification of PathogensRecruitingNCT048785491 country
- ZyVac-TCV Bangladesh StudyNot yet recruitingNCT06757283Phase 31 country
- Evaluation of Typhoid Conjugate Vaccine Effectiveness in GhanaRecruitingNCT04852185Phase 41 country
- Co-administration Study of OCV, TCV and MRNot yet recruitingNCT05771779Phase 3
- Clinical Efficacy of Typhoid Conjugate Vaccine (Vi-TCV) Among Children Age 9 Months Through 12 Years in Blantyre, MalawiActive, not recruitingNCT03299426Phase 31 country
- Immunogenicity and Tolerability of Booster Typhoid Conjugate Vaccine (TCV) 5-6 Years After Initial Dose in Children in Burkina FasoCompletedNCT07624175Phase 21 country
- Vellore Typhoid Vaccine Impact TrialCompletedNCT05500482Phase 41 country
- This Randomized Controlled Trial Evaluates the Comparative Efficacy of Intravenous Meropenem Alone Versus Intravenous Meropenem Combined With Oral Azithromycin in Children Aged 6 Months to Under 5 Years Diagnosed With Blood Culture-confirmed Extensively Drug-resistant Uncomplicated Typhoid FeverCompletedNCT07445282Phase 41 country
- The Azithromycin and Cefixime Treatment of Typhoid in South Asia Trial (ACT-South Asia Trial)CompletedNCT04349826Phase 41 country
- CVD 37000: Immunity and Microbiome Studies at Intestinal and Systemic Sites in Ty21a Vaccinated AdultsActive, not recruitingNCT03970304Phase 41 country
- WHNRC (Western Human Nutrition Research Center) Fiber Intervention StudyCompletedNCT04543877Early Phase 11 country
- Induction of Gut Permeability by an Oral VaccineActive, not recruitingNCT04083950Early Phase 11 country
- Efficacy of Levofloxacin Versus Ciprofloxacin in the Treatment of Childhood Typhoid FeverCompletedNCT07150065Phase 21 country
- Study to Evaluate the Safety, Tolerability and Immunogenicity of a Potential Enteric Fever VaccineCompletedNCT04349553Phase 11 country
- Typhoid Conjugate Vaccine Trial Among Children Younger Than 2 Years in Ouagadougou, Burkina FasoCompletedNCT03614533Phase 21 country
- Challenge Non-Typhoidal Salmonella (CHANTS) StudyActive, not recruitingNCT05870150Not applicable1 country
- Diagnosis and Staging of Typhoid Fever Using Surface-enhanced Raman Spectroscopy Liquid BiopsyCompletedNCT06546982Not applicable1 country
- Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy AdultsCompletedNCT05613205Phase 11 country
- Non-inferiority Trial of Locally Manufactured Typhoid Conjugate Vaccine 'Typhocon' in BangladeshCompletedNCT05475379Phase 1/21 country
- Effects of Aging on Primary and Secondary Vaccine ResponsesCompletedNCT03312699Phase 11 country
- Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) VaccinesCompletedNCT06104345Phase 41 country
- Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy AdultsCompletedNCT00679172Phase 21 country
- Nepal Undifferentiated Febrile Illness TrialCompletedNCT02773407Phase 31 country
- Evaluation Study of DPP® Typhoid AssayCompletedNCT055798211 country
- Global Genomic and Proteomic Profiling of African Children With Typhoid FeverCompletedNCT029472951 country
- Phase 4 Study To Assess The Safety Of Vivotif At Different Release Titers Among TravelersCompletedNCT023919091 country
- Understanding Typhoid Disease After VaccinationCompletedNCT01405521Phase 21 country
- Effectiveness of a Typhoid Conjugate Vaccine in DRCStatus unknownNCT05119426Phase 41 country
- TyVECO: Surveillance ProtocolStatus unknownNCT055621021 country
- Vaccines Against Salmonella TyphiCompletedNCT02324751Phase 21 country
- Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyCompletedNCT02192008Not applicable1 country
- Commercial Typhoid Tests Validation TrialCompletedNCT048016022 countries
- Understanding Paratyphoid InfectionCompletedNCT02100397Not applicable1 country
- Understanding How Salmonella Typhi Infects Humans (Bottlenecks)CompletedNCT03889067Not applicable1 country
- Investigating Typhoid Fever PathogenesisStatus unknownNCT03067961Not applicable1 country
- Non-inferiority and Safety Study of EuTCV Compared to Typbar-TCV in Healthy 6 Months-45 Years Aged ParticipantsCompletedNCT04830371Phase 2/31 country
- Typhoid Conjugate Vaccine Introduction in Navi Mumbai, IndiaCompletedNCT035542131 country
- Immune Equivalence Between Multi-dose and Single Dose Formulation of Vi-DT and Their Overall Safety (Phase III)CompletedNCT04204096Phase 31 country
- Safety, Reactogenicity and Immunogenicity of Vi-DT;Typhoid Conjugate VaccineCompletedNCT03527355Phase 21 country
- Comparison of Two Drugs Regimen in Treatment of Complicated Typhoid Fever in ChildrenCompletedNCT04154722Phase 41 country
- Cellular Immune Responses in Typhoid Fever Patients and VaccineesStatus unknownNCT03600025Phase 11 country
- Commercial Typhoid Tests ValidationStatus unknownNCT046734871 country
- Mobile Point of Care Diagnostic Testing for Ebola Virus Disease in DRCStatus unknownNCT042353614 countries