Thymus Neoplasms clinical trials
The registry lists 45 studies for Thymus Neoplasms across more than 10 countries. 13 are recruiting or about to start. 9 of them are mainly about Thymus Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 2 narrower conditions too, such as Thymoma: 175 studies, 54 open.
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Who runs them
National Cancer Institute (NCI) (9) · Samsung Medical Center (2) · M.D. Anderson Cancer Center (2) · Georgetown University (1) · Jonsson Comprehensive Cancer Center (1) · Grupo Espanol de Tumores Neuroendocrinos (1) · Ass. Prof. Jan Nyman (1) · Indiana University School of Medicine (1)
What is being tested here
Drugs under test in Thymus Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026Ivonescimab Combined with Chemotherapy As First-line Treatment of Relapsed or Metastatic Thymic Cancer: a Prospective, Single Arm, Phase II Trial · Sun Yat-sen University
- Dec 2026Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma · National Cancer Institute (NCI)
- Oct 2027A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers · Novartis Pharmaceuticals
- Nov 2027Hypofractionated Radiotherapy for Thymic Epithelial Tumors · Rongrong Zhou
Who these studies take
Of the 10 Thymus Neoplasms studies recruiting now, 4 (40%) set no upper age limit and 3 (30%) stop at 75 or younger. 1 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (10%) | 1 (10%) |
| 18 | 9 (90%) | 9 (90%) |
| 30 | 9 (90%) | 9 (90%) |
| 40 | 9 (90%) | 9 (90%) |
| 50 | 9 (90%) | 9 (90%) |
| 65 | 9 (90%) | 9 (90%) |
| 75 | 9 (90%) | 9 (90%) |
| 85 | 7 (70%) | 7 (70%) |
Across all 45 studies, recruiting or not: 16% stop at 75 or younger and 4% at 65; 7% take children; 0% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 45 of 45. search them.
- Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 11 country
- PT-112 in Subjects With Thymoma and Thymic CarcinomaRecruitingNCT05104736Phase 21 country
- Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial TumorsNot yet recruitingNCT07693855Not applicable1 country
- Prospective Data Collection Initiative on Thoracic MalignanciesRecruitingNCT069962491 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.RecruitingNCT05918302Phase 34 countries
- Molecular Analysis of Thoracic MalignanciesEnrolling by invitationNCT013857221 country
- An International Study on Pediatric Patients With Rare Tumors.RecruitingNCT070721431 country
- Molecular Analysis and Treatment Options of Thymic MalignanciesRecruitingNCT056679481 country
- Ivonescimab Combined with Chemotherapy As First-line Treatment of Relapsed or Metastatic Thymic Cancer: a Prospective, Single Arm, Phase II TrialNot yet recruitingNCT06750952Phase 2
- Hypofractionated Radiotherapy for Thymic Epithelial TumorsRecruitingNCT06692062Not applicable1 country
- A Study of KC1036 in Patients with Advanced Thymic TumorsRecruitingNCT05683886Phase 21 country
- Study on Proton Radiotherapy of Thymic MalignanciesRecruitingNCT04822077Not applicable1 country
- Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various CancersActive, not recruitingNCT04459273Phase 11 country
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 112 countries
- Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic CarcinomaActive, not recruitingNCT04417660Phase 21 country
- Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete ResectionActive, not recruitingNCT06189183Not applicable1 country
- Rapid Autopsy and Procurement of Cancer TissueTerminatedNCT018513951 country
- Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid TumorsTerminatedNCT04234113Phase 14 countries
- Study to Evaluate the Safety and Tolerability of RXC004 in Advanced MalignanciesCompletedNCT03447470Phase 11 country
- The Registry of Oncology Outcomes Associated with Testing and TreatmentCompletedNCT040284791 country
- Sunitinib for Advanced Thymus Cancer Following Earlier TreatmentCompletedNCT01621568Phase 21 country
- A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced MalignanciesCompletedNCT01325441Phase 1/22 countries
- Thoracic OncoGeriatric Assessment (TOGA) TrialsCompletedNCT005919811 country
- A Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsCompletedNCT03517488Phase 11 country
- Cardiac MRI Biomarker Testing (GCC 1618)TerminatedNCT026881661 country
- Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid TumorsCompletedNCT03023319Phase 11 country
- Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary MetastasesTerminatedNCT02859415Phase 1/21 country
- A Phase 2 Clinical Study of YY-20394 in Patients With Relapsed/Refractory Thymic CancerStatus unknownNCT04975061
- Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut OriginCompletedNCT02420691Phase 21 country
- Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic MalignanciesCompletedNCT00921739Phase 11 country
- Study of Hypofractionated Proton Radiation Therapy in Thoracic MalignanciesTerminatedNCT01165658Phase 11 country
- Pembrolizumab and Epacadostat in Patients With Thymic CarcinomaStatus unknownNCT02364076Phase 21 country
- A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic MalignanciesCompletedNCT01364727Phase 21 country
- 18F FLT Imaging Studies of Treatment Response for Lung Cancer and ThymomaWithdrawnNCT01610544Phase 2
- A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, MalignanciesTerminatedNCT01100944Phase 1/21 country
- A Phase II Study of Palbociclib for Recurrent or Refractory Advanced Thymic Epithelial TumorStatus unknownNCT03219554Phase 21 country
- Genetic Evaluation of Families With Endocrine CancersCompletedNCT017946761 country
- Prospective Study of Stereotactic Body Radiation Therapy for Thymoma Inoma: Therapeutic Effect and Toxicity AssessmentCompletedNCT03078699Not applicable1 country
- Cognitive Testing of Tobacco Use Measurement Items for Administration With Cancer Patients and SurvivorsCompletedNCT022338421 country
- Neoadjuvant Chemotherapy for Locally Advanced Thymic CancerCompletedNCT01312324Phase 21 country
- B-Receptor Signaling in CardiomyopathyCompletedNCT011358491 country
- Heated Chemotherapy for Cancers That Have Spread to the Chest CavityCompletedNCT01163552Phase 21 country
- A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic CancerCompletedNCT00369889Phase 21 country
- High Dose Somatostatin Analogues in Neuroendocrine TumorsCompletedNCT00990535Phase 21 country