Sudden Unexpected Death in Epilepsy clinical trials
The registry lists 23 studies for Sudden Unexpected Death in Epilepsy across 6 countries. 11 are recruiting or about to start. 12 of them are mainly about Sudden Unexpected Death in Epilepsy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Status
Who runs them
Hospices Civils de Lyon (7) · Mayo Clinic (2) · NYU Langone Health (2) · University Hospital, Montpellier (2) · Stichting Epilepsie Instellingen Nederland (1) · NHS Greater Clyde and Glasgow (1) · MedtronicNeuro (1) · The University of Texas Health Science Center, Houston (1)
What is being tested here
Drugs under test in Sudden Unexpected Death in Epilepsy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Fenfluramine | 1 | 0 | 1 |
| Fluoxetine | 0 | 1 | 2 |
| Naloxone | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Jan 2027Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLepsy · Hospices Civils de Lyon
- May 2027Effect of Rose Odor Exposure on Ictal Apnea · Vanderbilt University Medical Center
- Sep 2027Risk Factors for Sudden Unexplained Death in Epilepsy · NYU Langone Health
- Sep 2027The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project · The University of Texas Health Science Center, Houston
Who these studies take
Of the 10 Sudden Unexpected Death in Epilepsy studies recruiting now, 4 (40%) set no upper age limit and 5 (50%) stop at 75 or younger. 3 (30%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (20%) | 2 (20%) |
| 18 | 9 (90%) | 9 (90%) |
| 30 | 9 (90%) | 9 (90%) |
| 40 | 9 (90%) | 9 (90%) |
| 50 | 9 (90%) | 9 (90%) |
| 65 | 5 (50%) | 5 (50%) |
| 75 | 5 (50%) | 5 (50%) |
| 85 | 5 (50%) | 5 (50%) |
Across all 23 studies, recruiting or not: 39% stop at 75 or younger and 30% at 65; 39% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 23 of 23. search them.
- Genetic Markers of Cardiovascular Disease in EpilepsyRecruitingNCT028248221 country
- Study of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant EpilepsyRecruitingNCT07888543Not applicable1 country
- Intracranial CArtography of Cortical Contribution to Respiratory Load Compensation in EpilepsyRecruitingNCT07599150Not applicable1 country
- The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome ProjectRecruitingNCT07112365Phase 41 country
- Carbon Dioxide (CO2) Chemosensitivity and SUDEPRecruitingNCT04134754Not applicable1 country
- Effect of Rose Odor Exposure on Ictal ApneaRecruitingNCT07116421Early Phase 11 country
- Risk Factors for Sudden Unexplained Death in EpilepsyRecruitingNCT016624531 country
- A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet SyndromeRecruitingNCT07013331Not applicable1 country
- The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility StudyRecruitingNCT062922991 country
- Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLepsyRecruitingNCT06545214Not applicable1 country
- Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational StudyEnrolling by invitationNCT054239901 country
- Neural Circulatory Control and SUDEP Risk.Active, not recruitingNCT028139801 country
- National Network for the Study of Predictors and Prevention of Sudden Unexpected Death in Drug-resistant Partial EpilepsiesCompletedNCT025722971 country
- Efficacy of Naloxone in Reducing Postictal Central Respiratory Dysfunction in Patients With EpilepsyCompletedNCT02332447Phase 31 country
- Phenomenological Approach of Epilepsy in Patients With EpilepsyCompletedNCT029524561 country
- Improving Patient Communication About SUDEPCompletedNCT03502759Not applicable1 country
- Abnormal Ventilatory Response to Carbon Dioxide: a Potential Biomarker for Seizure Induced Respiratory Depression & Modification by SSRICompletedNCT02929667Phase 21 country
- Serotoninergic Pathways in Sudden and Unexpted Death in Epilepsy (SUDEP)TerminatedNCT027883181 country
- Cardiac Arrhythmias in Dravet SyndromeCompletedNCT024156863 countries
- Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring UnitTerminatedNCT02241798Not applicable1 country
- Risk Factors of SUDEPStatus unknownNCT030742791 country
- Efficacy of Fluoxetine Against Seizure-induced Central ApneasCompletedNCT02569970Phase 31 country
- Brain Stimulation for Epilepsy Long Term Follow-upCompletedNCT00736424