Solitary Pulmonary Nodule clinical trials
The registry lists 93 studies for Solitary Pulmonary Nodule across more than 10 countries. 20 are recruiting or about to start. 69 of them are mainly about Solitary Pulmonary Nodule (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-14.
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Who runs them
Boston Scientific Corporation (2) · Peking University People's Hospital (2) · Chinese Alliance Against Lung Cancer (2) · Beijing Aerospace General Hospital (2) · Erasme University Hospital (2) · Intuitive Surgical (2) · Wen-zhao ZHONG (2) · Seoul National University Hospital (2)
What is being tested here
Drugs under test in Solitary Pulmonary Nodule studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Indocyanine Green | 0 | 0 | 2 |
| Florilglutamic acid f-18 | 0 | 0 | 1 |
| Methylene Blue | 0 | 0 | 1 |
| Belinostat | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6, phase 3 first
- Nov 202718F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed Tomography · Phase 3 · Eastern Health, Canada
- Dec 2026Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath · ChromX Health
- Dec 2026Comparative Study on the Efficacy and Safety of Microwave Ablation and Lobectomy in the Treatment of Ground Glass Nodules Located in the Pulmonary Hilar Region · RenJi Hospital
- Apr 2027Plasma Metabolomics as a Tool to Distinguish PET-positive Malignant From PET-positive Benign Nodules · Hasselt University
- Aug 2027Smoking Cessation Before Bronchoscopy or CT-guided Puncture · RWTH Aachen University
- Oct 2027Radiomics for Distinguishing Benign and Malignant Lung Nodules · Assiut University
Who these studies take
Of the 12 Solitary Pulmonary Nodule studies recruiting now, 6 (50%) set no upper age limit and 1 (8%) stop at 75 or younger. 2 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (17%) | 2 (17%) |
| 18 | 8 (67%) | 8 (67%) |
| 30 | 9 (75%) | 9 (75%) |
| 40 | 12 (100%) | 12 (100%) |
| 50 | 12 (100%) | 12 (100%) |
| 65 | 12 (100%) | 12 (100%) |
| 75 | 11 (92%) | 11 (92%) |
| 85 | 9 (75%) | 9 (75%) |
Across all 93 studies, recruiting or not: 10% stop at 75 or younger and 2% at 65; 9% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Solitary Pulmonary Nodule studies take
Of 24 interventional studies with no phase under Solitary Pulmonary Nodule, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo9–43 · 24 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 93. Browse all 93 → or search them.
- Biomarkers for Risk Stratification in Lung CancerRecruitingNCT037747581 country
- Radiomics for Distinguishing Benign and Malignant Lung NodulesNot yet recruitingNCT07852000
- Intraoperative Longitude-Latitude-Depth Localization Versus Preoperative CT-Guided Percutaneous Lung Puncture Localization for 0.8-2 cm Peripheral Pulmonary NodulesRecruitingNCT07675889Not applicable1 country
- Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled TrialNot yet recruitingNCT07798362Not applicable
- Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion CharacterizationNot yet recruitingNCT077680461 country
- ICG Fluorescence Versus CO₂ Inflation-Deflation for Intersegmental Plane Identification During Thoracoscopic SegmentectomyNot yet recruitingNCT07745738Not applicable
- Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule EvaluationRecruitingNCT076234731 country
- Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulESRecruitingNCT05968898Not applicable1 country
- Smoking Cessation Before Bronchoscopy or CT-guided PunctureRecruitingNCT073227961 country
- Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled BreathRecruitingNCT065186551 country
- An Exploratory Clinical Study on the Safety and Efficacy of Autologous NK Cells in the Treatment of Pulmonary NodulesRecruitingNCT07185035Early Phase 11 country
- Plasma Metabolomics as a Tool to Distinguish PET-positive Malignant From PET-positive Benign NodulesRecruitingNCT07087080Not applicable1 country
- DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction SolutionRecruitingNCT053897741 country
- A Prospective, Non-interventional Cohort Study of Subsolid Pulmonary NodulesNot yet recruitingNCT064586731 country
- Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab ClassifierRecruitingNCT064266282 countries
- Virtual Bronchoscopic Navigation to Increase Diagnostic Yield in Patients With Pulmonary NodulesRecruitingNCT053831051 country
- Comparative Study on the Efficacy and Safety of Microwave Ablation and Lobectomy in the Treatment of Ground Glass Nodules Located in the Pulmonary Hilar RegionNot yet recruitingNCT05477251Not applicable
- 18F-2-fluoro-2-deoxy-D-glucose in Positron Emission Tomography Computed TomographyNot yet recruitingNCT04615156Phase 3
- Pulmonary Nodule CohortNot yet recruitingNCT04049422
- Mobile Lung Nodule Observatory for Worldwide, Evidenced-based ResearchRecruitingNCT026934961 country
- Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung NodulesActive, not recruitingNCT04574518Not applicable1 country
- LungVision AI-Augmented Fluoroscopic Navigation for Intraoperative Pulmonary Nodule LocalizationCompletedNCT07682012Not applicable1 country
- A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENBActive, not recruitingNCT06308120Not applicable1 country
- Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical PracticeCompletedNCT059639451 country
- Comprehensive Prospective Comparison Of Two Robotic Platforms In Anatomical Lung Resections: Clinical Outcomes And Cost-utility AnalysisActive, not recruitingNCT075375561 country
- Utility of CAML as Diagnostic for Early Stage Lung CancerTerminatedNCT039921831 country
- AI Assisted Detection of Chest X-RaysCompletedNCT060758361 country
- Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT Using Integrated Intraprocedural ImagingActive, not recruitingNCT06654271Not applicable1 country
- Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung NodulesActive, not recruitingNCT041714922 countries
- Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)CompletedNCT054156701 country
- The Watch the Spot TrialCompletedNCT02623712Not applicable1 country
- Early Adjuvant Diagnosis of Pulmonary Nodules Based on CTC.CompletedNCT061879351 country
- Added Value of a Small Camera (Iriscope) in the Endoscopic Diagnosis of Peripheral Lung Nodules and MassesCompletedNCT05445635Not applicable1 country
- Cios Mobile 3D Spin for Robotic BronchoscopyCompletedNCT047400471 country
- LungLB in Subjects Presenting With Indeterminate Pulmonary NodulesActive, not recruitingNCT051714911 country
- A Registry to Evaluate the Performance of the BDX-XL2 TestCompletedNCT037669581 country
- Percutaneous Localization: Open-label Registry of Thoracic SurgeryCompletedNCT040666991 country
- iNod™ Ultrasound-Guided Needle Biopsy System StudyWithdrawnNCT05804435Not applicable
- Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic SegmentectomyCompletedNCT05350137Not applicable1 country
- Liquid Biopsy With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung NodulesTerminatedNCT050667761 country
- Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)CompletedNCT03591445Not applicable1 country
- Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary TumorWithdrawnNCT048946821 country
- Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-makingActive, not recruitingNCT048573331 country
- Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled TrialCompletedNCT04302350Not applicable1 country
- 18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary NodulesCompletedNCT02448225Phase 21 country
- Virtual Management of Lung NodulesStatus unknownNCT04892524Not applicable1 country
- Prospective Post-market Data Collection for Ion Endoluminal System to Understand CT to Body DivergenceCompletedNCT047353411 country
- Methylation of cfDNA in Diagnosing and Monitoring Pulmonary NoduleCompletedNCT039892191 country
- Clinical Evaluation of Primary Sampling Scatter Correction for Chest TomosynthesisCompletedNCT04076696Not applicable1 country
- IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis StudyCompletedNCT037537241 country