ClinicalTrials.gg
RecruitingNCT07914764Updated Nov 4, 2026

68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor Diagnosis

An observational study in Medullary Thyroid Carcinoma, Small Cell Lung Cancer ( SCLC ) and Gastric Adenocarcinoma, sponsored by Nanjing First Hospital, Nanjing Medical University. Recruiting at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-11-04.

Sponsored by Nanjing First Hospital, Nanjing Medical University · Observational

From the registry’s dates

  • Started Aug 2026; still recruiting 3 months later.
Updated Nov 4, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
20
Ages
18 Years to 75 Years
Sex
All
01

Study summary

Evaluate the safety of the novel radioactive nuclide-labeled cholecystokinin receptor (CCK2R) targeted molecular probe, 68Ga-YQ-CC05, in clinical application, and verify its effectiveness in tumor diagnosis.

02

Conditions studied

  • Medullary Thyroid Carcinoma
  • Small Cell Lung Cancer ( SCLC )
  • Gastric Adenocarcinoma
03

In context

Carcinoma, Medullary

67 studies on the registry are indexed under Carcinoma, Medullary; 18 are open to participants now.

This study's planned enrollment of 20 is below the median of 105 across 15 observational studies indexed under Carcinoma, Medullary.

Browse Carcinoma, Medullary studies →

Lead sponsor

Nanjing First Hospital, Nanjing Medical University is the lead sponsor of 224 studies on the registry; 110 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

Participants were recruited through hospital electronic records and community health centers

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Volunteer to participate in the trial, with the patient or their legal guardian signing the informed consent form;
  • Volunteers are not limited by gender, and the age range is from 18 to 75 years old, inclusive;
  • Other imaging examination methods (CT, MRI, etc.) reveal tumor occupying lesions;
  • Tumor patients who can obtain the final pathological results.
  • Kidney: GFR > 50 ml/min, ERPF > 280 ml/min, platelet count (PLT) > 75,000/μL, white blood cell (WBC) > 3,000/μL, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) less than 3 times the normal value.

Exclusion criteria

Exclusion Criteria:

  • Individuals with a history of allergy to similar drugs (drugs with similar chemical or biological components to CCK2R), allergic constitution, or current allergic diseases;
  • Those who are currently participating in other clinical drug studies, or have previously participated in any clinical drug studies (excluding vitamins and minerals);
  • Other uncontrollable clinical issues (such as HIV, hepatitis C virus infection, active hepatitis B, or other severe chronic infections, as well as severe mental, neurological, cardiovascular, respiratory, and other systemic diseases);
  • Red blood cells (RBC) count less than 4×10\^12, white blood cells (WBC) count less than 3×10\^9, hemoglobin level less than 110g/L, and platelet count (PLT) less than 75,000×10\^9;
  • Obvious abnormalities in liver and kidney function, with GFR less than 50 ml/min;
  • Tumor burden greater than 50%, or significant spinal cord compression;
  • Expected survival duration less than half a year; chemotherapy within 6 months;
  • Having severe acute concomitant diseases or severe treatment-resistant mental disorders;
  • Pregnant and lactating women (where pregnancy is defined as a positive urine pregnancy test result);
  • Patients who are physically unfit for radiological examinations;
  • Other situations where the researcher deems it inappropriate for the participant to participate in the trial.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
20 participants (estimated)
Patient registry
No

Interventions

  • Diagnostic testIntravenous injection of 68Ga-YQ-CC05 for PET-CT examination

    Intravenous injection of 68Ga-YQ-CC05 imaging agent, with a dose of 0.05 mCi/Kg body weight, followed by PET-CT imaging 60 minutes after administration

06

What researchers measure

Primary outcomes

  1. SUVmax of lesion uptake value

    Time frame: 60 minutes after administration

07

Study locations

1 of 1 sites recruiting
08

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Aug 2026 (actual). Primary completion is estimated for Oct 2026, 2 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 29, 2026
First posted
Nov 4, 2026
StartActual
Aug 1, 2026
Primary completionEst.
Oct 31, 2026
CompletionEst.
Nov 30, 2026
Last update
Nov 4, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 4, 2026
Show all 1 update
  1. Nov 4, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

09

Registry details

Key details

Study ID
NCT07914764
Responsible party
Feng Wang (Chief physician, Nanjing First Hospital, Nanjing Medical University) — Principal investigator
First posted
Nov 4, 2026
Start date
Aug 1, 2026
Primary completion
Oct 31, 2026 (estimated)
Completion
Nov 30, 2026 (estimated)
Last update
Nov 4, 2026

Study contacts

Feng Wang
Contact
fengwangcn@hotmail.com
+8602552271491

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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