Scleroderma, Systemic: all 695 studies
Page 1 of 7. Open to participants first (224), then studies with results posted, then the rest; newest registration first within each.
- A Clinical Study on Systemic Sclerosis and the Validation of French-language Questionnaires Assessing Disability, Quality of Life, and Disease Status.Not yet recruitingNCT07888842
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 1
- Using AI-Assisted Cameras to Track Hand Exercises in Scleroderma PatientsNot yet recruitingNCT07858838Not applicable
- C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard TherapyNot yet recruitingNCT07854483Phase 1
- Obinutuzumab in Systemic SclerosisNot yet recruitingNCT07842523Phase 2
- The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic SclerosisRecruitingNCT07842133Not applicable
- Home-based Exercise for Improving Health-related Quality of Life in Systemic SclerosisNot yet recruitingNCT07840430Not applicable
- Combined Growth Differentiation Factor-15 (GDF-15) and Lung Ultrasound for ILD Screening in Rheumatoid Arthritis and Systemic SclerosisNot yet recruitingNCT07839221
- Investigation of Type I Interferon Excess in Patients With Systemic Autoimmune Diseases and Genetic Type I InterferonopathiesNot yet recruitingNCT07837986Not applicable
- Clinical Cohort Study of Systemic SclerosisRecruitingNCT07836361
- Rituximab vs Placebo for Maintenance in Systemic Sclerosis - Interstitial Lung DiseaseNot yet recruitingNCT07827742Phase 2
- Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic SclerosisNot yet recruitingNCT07821398Phase 2
- Nebulized UC-EVs for Recurrent or Refractory IMIDs With Lung InvolvementNot yet recruitingNCT07806045Early Phase 1
- FT839 in Autoimmune DiseasesRecruitingNCT07800871Phase 1/2
- A Study to Learn About a Medicine Called PF-08154225 in Participants With Autoimmune DiseasesNot yet recruitingNCT07782450Phase 1/2
- A Study to Test CRT-402 in Refractory Autoimmune DiseaseRecruitingNCT07778446Phase 1/2
- Efficacy of A Non-Invasive Botulinum Toxin Microneedle Pad for the Treatment of Secondary Raynaud's PhenomenonNot yet recruitingNCT07759557Phase 3
- A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon AttacksNot yet recruitingNCT07748000Phase 2
- A Phase II Study of TollB-001 Tablets in Systemic SclerosisNot yet recruitingNCT07745725Phase 2
- Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular ResearchNot yet recruitingNCT07737470
- Mycophenolate After Stem Cell Transplant for Systemic SclerosisNot yet recruitingNCT07734012Phase 2
- A Study of ATG-201 in Adult Participants With Autoimmune DiseasesNot yet recruitingNCT07732309Phase 1
- BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune DiseaseNot yet recruitingNCT07729995Phase 1
- Finger Versus Earlobe Pulse Oximetry During the 6-Minute Walk Test in Interstitial Lung DiseaseRecruitingNCT07723872
- Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic SclerosisNot yet recruitingNCT07717060Not applicable
- Hyaluronidase for Sclerodactyly in Systemic Sclerosis TrialNot yet recruitingNCT07697274Early Phase 1
- A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard TherapyNot yet recruitingNCT07676266Phase 1
- Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)Not yet recruitingNCT07650565Not applicable
- A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the BodyRecruitingNCT07649265Phase 1
- TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)Not yet recruitingNCT07642297
- A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.RecruitingNCT07641634Phase 1/2
- CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune DiseasesNot yet recruitingNCT07596680Early Phase 1
- CD19/BCMA UCAR-T for B Cell-Related Autoimmune DiseaseRecruitingNCT07586267Early Phase 1
- Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune DiseasesRecruitingNCT07558850Not applicable
- Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic DiseasesNot yet recruitingNCT07544225Phase 1
- Objective Assessment of Skin Damage Using ADHELASKIN in Patients With Systemic SclerosisRecruitingNCT07543679Not applicable
- Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Systemic SclerosisNot yet recruitingNCT07535931Phase 1/2
- MTS109 in Patients With Refractory Autoimmune DiseasesRecruitingNCT07526350Early Phase 1
- Safety and Preliminary Efficacy of HN2302 in Patients With Autoimmune DiseasesNot yet recruitingNCT07523282Phase 1
- Immun4Cure Cohort of Autoimmune DiseasesRecruitingNCT07515638
- Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune DiseaseRecruitingNCT07507201Early Phase 1
- Efficacy and Safety of Firsekibart in the Treatment of Systemic SclerosisNot yet recruitingNCT07502105Not applicable
- A Study to Test Whether Nerandomilast Helps People With Systemic SclerosisRecruitingNCT07497087Phase 3
- Phase IIa Trial of Anti-CD19 CAR T-Cells in Systemic Sclerosis Resistant to Immunosuppressive TherapyRecruitingNCT07493395Phase 2
- Controlling Hyperactive Immunity With Long-lived LymphocytesRecruitingNCT07473154Phase 1/2
- A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune DiseasesRecruitingNCT07413341Phase 1
- A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101RecruitingNCT07403188
- Systemic Sclerosis DIet for GastrointESTinal SymptomsRecruitingNCT07402226Not applicable
- Correlation Between Circulating Fibroblast Activation Protein (FAP) and Fibrosis in Two Diseases (Rheumatoid Arthritis and Systemic Sclerosis)Not yet recruitingNCT07393217
- Safety and Efficacy of Adipose-Derived Regenerative Cells (ADRCs) for Improving Hand Dysfunction in Systemic SclerosisRecruitingNCT07360808Not applicable
- Western Sweden Systemic Sclerosis ProjectRecruitingNCT07345052
- Familial Systemic SclerodermaRecruitingNCT07343115
- A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic SclerosisNot yet recruitingNCT07335562Phase 3
- Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclErodermaNot yet recruitingNCT07326033Phase 2
- CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune DiseaseRecruitingNCT07305116Phase 1
- Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune DiseasesRecruitingNCT07301164Early Phase 1
- A Study of AZD0120 in Autoimmune DiseasesRecruitingNCT07295847Phase 1
- Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With SclerodermaRecruitingNCT07292961Not applicable
- A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune DiseasesRecruitingNCT07284797Phase 1
- Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune DeficienciesRecruitingNCT07251179
- Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease PatientsRecruitingNCT07249060
- Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune DiseasesRecruitingNCT07246096Early Phase 1
- Topical Cannabidiol Lotion for Pruritus Relief in SclerodermaRecruitingNCT07245238Phase 3
- Multicenter Study on the Development of Pulmonary Arterial Hypertension Screening Models Based on Artificial Intelligence for Patients With Systemic SclerosisRecruitingNCT07236970
- Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune DiseasesRecruitingNCT07236801Phase 1
- Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography ImagesRecruitingNCT07228429
- A Study of CD19 UCAR-T Cells in Subjects With Autoimmune DiseasesNot yet recruitingNCT07212322Not applicable
- Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic SclerosisNot yet recruitingNCT07209644
- Mass Spectrometry-based Immune Profiling in Autoimmune DiseasesEnrolling by invitationNCT07188285
- Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic DiseasesRecruitingNCT07184450Phase 1
- Patients Diagnosed With Scleroderma: Physical Performance and FunctionalityRecruitingNCT07183072
- Patients Diagnosed With Scleroderma and Their Chewing and Swallowing PerformanceRecruitingNCT07182981
- Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL QuestionnaireRecruitingNCT07182968
- Exploring the Patterns of Sleep Disordered Breathing in Systemic Sclerosis PatientsNot yet recruitingNCT07175246
- A Study of OL-CD19-GDT in Relapsed/ Refractory Autoimmune DiseasesRecruitingNCT07167537Phase 1
- A Study of GB261 in Systemic SclerosisNot yet recruitingNCT07159009Early Phase 1
- A Study of Cizutamig in Systemic SclerosisNot yet recruitingNCT07158996Early Phase 1
- Clinical Assessment for Rheumatologic Disease - Research and Advancement in Safety and EfficacyRecruitingNCT07150000
- Anti CD19/BCMA CAR Gene Therapy for Autoimmune DiseasesRecruitingNCT07121777Not applicable
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 1
- Open Label Treprostinil Raynaud's StudyRecruitingNCT07112183Phase 4
- A Clinical Study of YTS109 Cell for R/R Autoimmune DiseasesRecruitingNCT07104721Phase 1
- Diffuse Cutaneous Scleroderma (DSSc) SFDI StudyRecruitingNCT07090226Not applicable
- Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic DiseasesRecruitingNCT07087912Phase 4
- Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune DiseasesRecruitingNCT07085676Phase 1
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune DiseaseRecruitingNCT07085104Phase 1
- EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular DiseasesRecruitingNCT07077304
- GC012F in Patients With Autoimmune DiseasesNot yet recruitingNCT07072884Early Phase 1
- CAR-T Cells Therapy for Patients With Autoimmune DiseasesRecruitingNCT07052565Not applicable
- A Study of Nemolizumab for the Treatment of Adults With Systemic SclerosisRecruitingNCT07047690Phase 2
- A Study of KITE-363 in Participants With Refractory Autoimmune DiseasesEnrolling by invitationNCT07038447Phase 1
- PPI Refractory - GERD Mechanisms in Systemic SclerosisNot yet recruitingNCT07022912
- Pathogenic Mechanisms Involved in the Initiation and Progression of Systemic SclerosisNot yet recruitingNCT07015060Not applicable
- Medical Follow-up of New Cases of Polyarthritis in Children and Young AdultsRecruitingNCT07000916
- The Clinical Study on the Treatment of SSc With UTAA91 Injection.RecruitingNCT07000682Early Phase 1
- AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.RecruitingNCT06991114Phase 2
- Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.Not yet recruitingNCT06982534Early Phase 1
- A Study of OL-108 in Relapsed/Refractory Autoimmune DiseasesRecruitingNCT06980597Phase 1
- UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune DiseasesNot yet recruitingNCT06978738Phase 1
- A Clinical Study of YTS109 Cell in R/R Autoimmune DiseasesRecruitingNCT06978647Phase 1