Restless Legs Syndrome: all 254 studies

Page 1 of 3. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.

• Intravenous Iron in the Management of Drug-resistant Restless Legs syndromeINot yet recruitingNCT07822607Phase 2
• The Effect of Acupressure on Restless Legs Syndrome and Pruritus in Patients Undergoing HemodialysisNot yet recruitingNCT07814443Not applicable
• Efficacy and Safety of Super High-Flux Hemodialysis in Maintenance Dialysis Patients. SHINE-RLS (Super High-flux Dialysis Improves Neuro-symptoms and Efficacy in Restless Legs Syndrome)Not yet recruitingNCT07794826Not applicable
• Neuromodulation to Overcome Severe Restless Legs SyndromeNot yet recruitingNCT07780032Not applicable
• Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS)RecruitingNCT07675109Not applicable
• Effects of Static Stretching and Strength Training on Antenatal Restless Leg SyndromeRecruitingNCT07642089Not applicable
• Comparative Effects of Aerobic and Muscle Relaxation Exercises in Pregnant Women With Restless Leg SyndromeRecruitingNCT07628387Not applicable
• Study on the Efficacy of Spinal Cord Stimulation in Patients With Severe Refractory Primary or Secondary RLSNot yet recruitingNCT07571733Not applicable
• Novel Calcium Channel Modulators in RLS and Variants: Efficacy & SafetyRecruitingNCT07453862Phase 1
• Tonic Motor Activation (TOMAC) Therapy in Patients With Restless Legs Syndrome and Dopaminergic AugmentationNot yet recruitingNCT07397247Not applicable
• Combined Effects of Near-Infrared Light and Vibration on Diabetic Patients With Restless Leg SyndromeNot yet recruitingNCT07308080Not applicable
• Study on the Mechanism of Gut Microbiota Mediating Restless Legs Syndrome Through Iron MetabolismNot yet recruitingNCT07307482
• Effect of Autogenic Training on Hemodialysis PatientsNot yet recruitingNCT07276828Not applicable
• Tolerability and Efficacy of CBD Extract for RLS TreatmentNot yet recruitingNCT07224932Phase 2
• A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With DipyridamoleRecruitingNCT07199504Phase 2/3
• The Effect of Spinal Cord Stimulators on Restless Leg SyndromeRecruitingNCT07179406Not applicable
• Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs SyndromeRecruitingNCT07144631Not applicable
• The Suggested Immobilization Test With Exploratory Heart Rate Variability Analysis for Diagnosis of Restless Legs SyndromeRecruitingNCT07110961Not applicable
• A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless SleepNot yet recruitingNCT07061470Phase 1/2
• Functional Connectivity of the Interoceptive Network in RLSRecruitingNCT07001891Not applicable
• Efficacy of Interval Aerobic Training Versus Laser Puncture Therapy on Restless Leg Syndrome in Copd PatientNot yet recruitingNCT06955000Not applicable
• Comparative Effectiveness of Myofacial Release vs Cupping Therapy on Quality of Life in Restless Leg Syndrome With Knee O.A.RecruitingNCT06918847Not applicable
• Using Cannabis to Treat Restless Legs SyndromeRecruitingNCT06863740Not applicable
• Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in HemodialysisRecruitingNCT06806891Not applicable
• Effects of PNF Stretching vs Conventional Physical Therapy on the Symptoms of Restless Leg Syndrome in Elderly Population.RecruitingNCT06747741Not applicable
• Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist TreatmentRecruitingNCT06726785
• Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's DiseaseRecruitingNCT06684782
• A Randomized, Placebo-controlled Trial of Prednisone in Refractory Restless Legs Syndrome: a Pilot StudyNot yet recruitingNCT06631300Phase 1/2
• Blood Changes After Exercise in Restless Legs SyndromeRecruitingNCT06481176Not applicable
• The Effect of Kinesio Taping and Manual Lymph Drainage on Pregnant Women With Restless Legs SyndromeRecruitingNCT06233773Not applicable
• Gut Microbiota and Bacterial Translocation in Restless Legs SyndromeRecruitingNCT05985421
• The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron HyperexcitabilityRecruitingNCT05908214Not applicable
• Ecological Momentary Assessment in Patients With Restless Legs SyndromeRecruitingNCT05695963Not applicable
• Mainz Register of Patients With Sleep DisordersRecruitingNCT05321355
• Clinical Features Associated With Restless Legs Syndrome.RecruitingNCT05044520
• Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's DiseaseRecruitingNCT03082755Phase 4
• Analysis of Sympathetic Activity in Willis-Ekbom DiseaseRecruitingNCT02929732Not applicable
• Quality Improvement and Practice Based Research in Neurology Using the EMREnrolling by invitationNCT02670161Phase 4
• Executive Dysfunction in Restless Legs Syndrome: Clinical Correlates and Outcome After Therapeutic ManagementRecruitingNCT01823354Not applicable
• Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLSCompletedNCT05196828Not applicableResults posted
• Noninvasive Peripheral Nerve Stimulation for Medication-Refractory Primary RLS (The RESTFUL Study)CompletedNCT04874155Not applicableResults posted
• Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUDTerminatedNCT04759703Phase 2/3Results posted
• Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic InsomniaCompletedNCT04706091Phase 4Results posted
• Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication ReductionCompletedNCT04698343Not applicableResults posted
• Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement DisorderTerminatedNCT04610827Phase 4Results posted
• Advancing Understanding of Transportation OptionsCompletedNCT04141891Not applicableResults posted
• A Follow-up Study of Rotigotine Patch in Adolescent Subjects With Restless Legs SyndromeTerminatedNCT03992196Phase 3Results posted
• A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown CauseTerminatedNCT03728933Phase 3Results posted
• Spinal Cord Stimulation for Restless Legs SyndromeCompletedNCT03539081Not applicableResults posted
• Treatment of RLS/WED Symptoms Through Sensory Counter-stimulationCompletedNCT03249779Not applicableResults posted
• Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific AntagonistCompletedNCT03218969Phase 1/2Results posted
• A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome PatientsCompletedNCT03053427Phase 4Results posted
• Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency AnemiaTerminatedNCT02826681Phase 2Results posted
• The Effect of Horizant (Gabapentin Enacarbil) on AugmentationCompletedNCT02642315Not applicableResults posted
• A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg SyndromeCompletedNCT02526277Not applicableResults posted
• Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)CompletedNCT02499354Phase 2Results posted
• Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLSCompletedNCT02397057Phase 3Results posted
• Study to Investigate Pharmacokinetics (PK) of Pramipexole in Pediatric Patients Who Are Individually Optimized to Stable Pramipexole Doses for the Treatment of Idiopathic Restless Legs Syndrome (RLS)CompletedNCT02231918Phase 2Results posted
• Prevalence of OSAS in Chinese Elderly and Its CPAP ComplianceCompletedNCT02085720Not applicableResults posted
• Fire Fighter Fatigue Management Program: Operation Healthy SleepCompletedNCT01988129Not applicableResults posted
• Switching From Oral Dopamine Agonists to RotigotineCompletedNCT01976871Phase 4Results posted
• Investigation of Efficacy of incobotulinumtoxinA (Xeomin) in Relieving Symptoms of Restless Leg Syndrome.CompletedNCT01931878Phase 2Results posted
• Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment StudyCompletedNCT01668667Phase 4Results posted
• Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs Syndrome (RLS)CompletedNCT01569464Phase 3Results posted
• A Long-Term Extension Trial From Late Phase II of SPM 962 in Patients With Restless Legs SyndromeCompletedNCT01562743Phase 2Results posted
• A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring HemodialysisCompletedNCT01537042Phase 3Results posted
• Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Legs SyndromeCompletedNCT01498120Phase 2Results posted
• Dose Escalating Study of Rotigotine in Pediatric Subjects With Restless Legs SyndromeCompletedNCT01495793Phase 2Results posted
• Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs SyndromeCompletedNCT01455012Phase 4Results posted
• Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced AugmentationCompletedNCT01386944Results posted
• Intravenous (IV) Iron Preparation (VIT-45) in the Treatment of Restless Legs Syndrome (RLS)CompletedNCT01382901Phase 2Results posted
• Simulated Driving Study in Restless Legs SyndromeCompletedNCT01332318Phase 2Results posted
• Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs SyndromeCompletedNCT01332305Phase 2Results posted
• REQUIP RLS Post Marketing SurveillanceCompletedNCT01327339Results posted
• Survey on Long-Term Use of BI-Sifrol® Tablets in Patients With Restless Legs SyndromeCompletedNCT01174459Results posted
• Safety and Effect of Mirapex(Pramipexole) Tablet Among Korean RLSCompletedNCT01170091Results posted
• Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)CompletedNCT01138124Results posted
• Non-interventional Study (NIS) in Patients With Restless Legs Syndrome in Daily PractiseCompletedNCT01113710Results posted
• Study of SPM 962 in Patients With Restless Legs Syndrome (RLS)CompletedNCT01084551Phase 3Results posted
• Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)TerminatedNCT00996944Phase 2Results posted
• Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep DisturbanceCompletedNCT00991276Phase 3Results posted
• Iron Sucrose In The Treatment of Restless Legs Syndrome: Safety of Three Dose Regimens as Evaluated by Clinical AssessmentsCompletedNCT00895232Phase 2Results posted
• Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Syndrome (RLS)CompletedNCT00887289Results posted
• Long Term Study Of Pregabalin In Idiopathic Restless Legs Syndrome PatientsCompletedNCT00806026Phase 3Results posted
• Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep DisturbanceCompletedNCT00748098Phase 3Results posted
• Sifrol (Pramipexole) Onset of Action and Impact: a 12-weeks Observational Study in Patients With Primary Restless Legs SyndromeCompletedNCT00721279Results posted
• Intravenous Iron Metabolism in Restless Legs SyndromeCompletedNCT00685815Phase 2Results posted
• Lyrica Dose Response Study With Restless Legs Syndrome (RLS) PatientsCompletedNCT00676403Phase 2Results posted
• A Placebo-Controlled Study for SPM 962 in Restless Legs Syndrome (RLS) PatientsCompletedNCT00666965Phase 2Results posted
• Pramipexole in Out-patients With Idiopathic Restless Legs Syndrome (IRLS)CompletedNCT00654498Phase 3Results posted
• Bupropion and Restless Legs SyndromeCompletedNCT00621517Phase 2/3Results posted
• Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs SyndromeCompletedNCT00530790Phase 2Results posted
• Long-term Open-label Trial in Idiopathic Restless Legs Syndrome (RLS)CompletedNCT00498186Phase 2Results posted
• Botulinum Toxin to Treat Restless Legs SyndromeCompletedNCT00479154Phase 1/2Results posted
• Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS)CompletedNCT00472199Phase 4Results posted
• A Randomised, Comparing Fixed Doses of Pramipexole to Investigate the Efficacy and Safety in Patients With RLS.CompletedNCT00390689Phase 3Results posted
• Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of RLS SymptomsCompletedNCT00389831Phase 2Results posted
• XP13512 vs. Placebo in Patients With Restless Legs Syndrome.CompletedNCT00365352Phase 3Results posted
• The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs SyndromeCompletedNCT00357097Phase 3Results posted
• XP13512 (Gabapentin Enacarbil) Extension Study in Patients With Restless Legs Syndrome.CompletedNCT00333359Phase 3Results posted

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