Paraplegia clinical trials
The registry lists 151 studies for Paraplegia across more than 10 countries. 36 are recruiting or about to start. 39 of them are mainly about Paraplegia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Wandercraft (8) · VA Office of Research and Development (7) · James J. Peters Veterans Affairs Medical Center (4) · ABLE Human Motion S.L. (4) · University Hospital, Montpellier (4) · University of Miami (3) · Institut National de la Santé Et de la Recherche Médicale, France (3) · University of Manitoba (3)
What is being tested here
Drugs under test in Paraplegia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Aug 2027Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI) · Phase 3 · Northwell Health
- Nov 2026Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury · Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Dec 2026Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of Gait · University of Zurich
- Dec 2026Epidural Electrical Stimulation to Restore Standing and Walking in Patients with Chronic Paralysis Due to Spinal Cord Injury: a Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation · University of Sao Paulo General Hospital
- Dec 2026Virtual Peer Coaching in Manual Wheelchair Skills · University of Pittsburgh
- Dec 2026Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury · MetroHealth Medical Center
- Dec 2026tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCI · Beijing Tsinghua Chang Gung Hospital
- Dec 2026Natural History Study of Patients with HPDL Mutations · University of California, San Diego
- Jan 2027Epidural Stimulation After Neurologic Damage · University of Minnesota
- Feb 2027Comparison Between Palpatory and Ultrasound-guided Methods for Botulinum Toxin Administration in Spastic Paraplegia · Universidade Federal Fluminense
Who these studies take
Of the 32 Paraplegia studies recruiting now, 15 (47%) set no upper age limit and 14 (44%) stop at 75 or younger. 6 (19%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (16%) | 5 (16%) |
| 18 | 23 (72%) | 23 (72%) |
| 30 | 30 (94%) | 30 (94%) |
| 40 | 29 (91%) | 29 (91%) |
| 50 | 29 (91%) | 29 (91%) |
| 65 | 27 (84%) | 27 (84%) |
| 75 | 23 (72%) | 23 (72%) |
| 85 | 17 (53%) | 17 (53%) |
Across all 151 studies, recruiting or not: 52% stop at 75 or younger and 34% at 65; 15% take children; 0% are for women only and 4% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Paraplegia studies take
Of 60 interventional studies with no phase under Paraplegia, half reached primary completion within 37 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 37 mo12–131 · 60 studies | — | 40 mo23–131 · 44 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord InjuryNov 3, 2026NCT07846410
Stopped1
Newly registered1
- tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCIOct 30, 2026NCT07907952
Studies
Recruiting first, then most recently updated. Showing 50 of 151. Browse all 151 → or search them.
- Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord InjuryRecruitingNCT03965299Not applicable1 country
- Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord InjuryRecruitingNCT05626816Not applicable1 country
- Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)RecruitingNCT07625332Phase 2/31 country
- At-Home Genital Nerve Stimulation for SCI BowelRecruitingNCT06836739Not applicable1 country
- Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord InjuryRecruitingNCT07846410Not applicable1 country
- tSCS Combined With Rehabilitation Training in Treating Paraplegic Patients After SCIRecruitingNCT07907952Not applicable1 country
- A Neuroprosthesis for Seated Posture and BalanceRecruitingNCT01474148Not applicable1 country
- Personal Exoskeleton or Manual Wheelchair: a Comparison of Performance and Satisfaction in Activities of Daily Living Among People With Spinal Cord Injuries, Using the SCED Methodology.Not yet recruitingNCT07828912Not applicable1 country
- Comparison Between Palpatory and Ultrasound-guided Methods for Botulinum Toxin Administration in Spastic ParaplegiaRecruitingNCT07803276Phase 41 country
- Psilocybin to Treat Depression in Spinal Cord InjuryRecruitingNCT07251491Phase 1/21 country
- Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord InjuryEnrolling by invitationNCT07732868Not applicable1 country
- Facilitating Neuroplastic Changes of Acute Stroke SurvivorsRecruitingNCT06404268Phase 1/21 country
- Promoting Neuroplastic Changes of Patients With TBIRecruitingNCT06465290Not applicable1 country
- Evaluation of an Advanced Lower Extremity NeuroprosthesesRecruitingNCT00623389Not applicable1 country
- Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)RecruitingNCT05518188Phase 1/21 country
- Deep Brain Stimulation in Patients With Incomplete Spinal Cord Injury for Improvement of GaitRecruitingNCT03053791Not applicable1 country
- Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.RecruitingNCT06692712Phase 32 countries
- Self-balancing Personal Exoskeleton for SCI (WIP)RecruitingNCT07536386Not applicable1 country
- Virtual Peer Coaching in Manual Wheelchair SkillsRecruitingNCT06295146Not applicable1 country
- Epidural Stimulation After Neurologic DamageRecruitingNCT03026816Not applicable1 country
- Registry and Natural History Study for Early Onset Hereditary Spastic ParaplegiaRecruitingNCT047128121 country
- Safety and Feasibility of TWIICE Rise - Phase 2RecruitingNCT07461259Not applicable1 country
- SCI Epidemiology and ComplicationsNot yet recruitingNCT074254701 country
- Self-balancing Personal Exoskeleton for SCI (WINY)RecruitingNCT07222033Not applicable1 country
- Natural History Study of Patients with HPDL MutationsRecruitingNCT058482711 country
- Turkish Lower-Extremity Motor Activity Log (LE-MAL)RecruitingNCT061568131 country
- Epidural Electrical Stimulation to Restore Standing and Walking in Patients with Chronic Paralysis Due to Spinal Cord Injury: a Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive RehabilitationRecruitingNCT06847295Not applicable1 country
- Neuromodulation With Spinal Stimulation MethodsRecruitingNCT06272279Not applicable1 country
- Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment StudyEnrolling by invitationNCT03225625Not applicable1 country
- Cognitive Disorders in Hereditary Spastic Paraplegia Type 4RecruitingNCT062609821 country
- Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any GenesisRecruitingNCT06072001Phase 31 country
- Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any GenesisRecruitingNCT06071949Phase 31 country
- The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) PatientsRecruitingNCT04050696Not applicable2 countries
- Safety and Feasibility of TWIICE RiseRecruitingNCT05926310Not applicable1 country
- Cord Blood Cells in Patients With Acute SCIRecruitingNCT05693181Phase 1/21 country
- A Registered Cohort Study on Spastic ParaplegiaRecruitingNCT040064181 country
- Self-balancing Personal Exoskeleton for SCICompletedNCT06777576Not applicable1 country
- Natural History of Shoulder Pathology in Manual Wheelchair UsersActive, not recruitingNCT026009101 country
- Self-balancing Personal Exoskeleton for SCI (Site 2)CompletedNCT06814015Not applicable1 country
- Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With ParaplegiaWithdrawnNCT07583576Not applicable
- SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic ParaplegiasCompletedNCT0014082915 countries
- A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)TerminatedNCT05394064Phase 1/22 countries
- Transspinal Stimulation Plus Locomotor Training for SCICompletedNCT04807764Not applicable1 country
- Healthcare Professionals' Satisfaction With Various Exoskeleton ModelsCompletedNCT077679551 country
- Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb RehabilitationActive, not recruitingNCT06243952Not applicable1 country
- Assessing Transition Practices for Children With Disabilities: Pathways to a Successful AdulthoodCompletedNCT077065171 country
- Epidural and Dorsal Root Stimulation in Humans With Spinal Cord InjuryCompletedNCT04736849Not applicable1 country
- "Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"CompletedNCT05563402Not applicable1 country
- Improving Clinician Capacity to Provide Interventions for Manual Wheelchair UsersCompletedNCT06294834Not applicable1 country
- Mobile Manual Standing Wheelchair for SCICompletedNCT04668326Not applicable1 country