Osteosarcoma: all 446 studies

Page 2 of 5. Open to participants first (117), then studies with results posted, then the rest; newest registration first within each.

• ICONIC: Improving Outcomes Through Collaboration in OsteosarComaRecruitingNCT04132895
• GISAR German Interdisciplinary Sarcoma RegistryRecruitingNCT04122872
• BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of BreastAvailableNCT04091295
• Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomasRecruitingNCT04055220Not applicable
• Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway AlterationRecruitingNCT04040205Phase 2
• Losartan + Sunitinib in Treatment of OsteosarcomaRecruitingNCT03900793Phase 1
• Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory OsteosarcomaRecruitingNCT03721068Phase 1
• Pediatric PET/MR Image RegistryRecruitingNCT03458520
• Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasRecruitingNCT03442465
• Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.RecruitingNCT03242382Phase 2
• Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary MetastasesRecruitingNCT03093909Phase 1
• Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingNCT02508038Phase 1
• Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid TumorsRecruitingNCT02013336Phase 1
• Reduced Intensity Haploidentical BMT for High Risk Solid TumorsRecruitingNCT01804634Phase 2
• Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentRecruitingNCT01790152
• Molecular Analysis Of Solid TumorsRecruitingNCT01050296
• Clinical Orthopaedic Data Bank (Acute and Chronic)RecruitingNCT00411060
• A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid TumorsCompletedNCT05093322Phase 1/2Results posted
• Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed OsteosarcomaTerminatedNCT04751383Phase 1Results posted
• Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Paediatric Participants With Solid Tumors (SCOOP)TerminatedNCT04544995Phase 1Results posted
• Olaparib With Ceralasertib in Recurrent OsteosarcomaActive, not recruitingNCT04417062Phase 2Results posted
• 18F-FTC-146 PET/CT in Newly-Diagnosed OsteosarcomaTerminatedNCT04365660Phase 2Results posted
• Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04320888Phase 2Results posted
• Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04284774Phase 2Results posted
• A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
• Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT04195555Phase 2Results posted
• A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory OsteosarcomaCompletedNCT04154189Phase 2Results posted
• Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor CancersTerminatedNCT03860207Phase 1/2Results posted
• M6620 (VX-970) in Selected Solid TumorsCompletedNCT03718091Phase 2Results posted
• Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03698994Phase 2Results posted
• Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03526250Phase 2Results posted
• Gemcitabine Plus Ascorbate for Sarcoma in AdultsTerminatedNCT03468075Phase 2Results posted
• Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric PatientsTerminatedNCT03458728Phase 1/2Results posted
• Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological MalignanciesTerminatedNCT03422679Phase 1/2Results posted
• Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid TumorsCompletedNCT03320330Phase 1/2Results posted
• Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03233204Phase 2Results posted
• Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03220035Phase 2Results posted
• Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03213704Phase 2Results posted
• Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213678Phase 2Results posted
• Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213665Phase 2Results posted
• Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03213652Phase 2Results posted
• Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)Active, not recruitingNCT03155620Phase 2Results posted
• Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerCompletedNCT03154190Not applicableResults posted
• Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the ExtremityTerminatedNCT03139318Not applicableResults posted
• A Phase II Trial of Avelumab in Patients With Recurrent or Progressive OsteosarcomaCompletedNCT03006848Phase 2Results posted
• Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory SarcomaCompletedNCT02945800Phase 2Results posted
• Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare TumorsActive, not recruitingNCT02867592Phase 2Results posted
• Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms TumorsTerminatedNCT02581384Phase 1/2Results posted
• Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated OsteosarcomaCompletedNCT02517918Phase 1Results posted
• Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by SurgeryCompletedNCT02500797Phase 2Results posted
• Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory OsteosarcomaCompletedNCT02487979Phase 2Results posted
• Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent OsteosarcomaCompletedNCT02484443Phase 2Results posted
• Denosumab in Treating Patients With Recurrent or Refractory OsteosarcomaCompletedNCT02470091Phase 2Results posted
• A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS)TerminatedNCT02441309Phase 2Results posted
• Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With OsteosarcomaCompletedNCT02432274Phase 1/2Results posted
• Combination of MK3475 and Metronomic Cyclophosphamide in Patients With Advanced Sarcomas : Multicentre Phase II TrialCompletedNCT02406781Phase 2Results posted
• Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone SarcomasCompletedNCT02357810Phase 2Results posted
• Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or SarcomasCompletedNCT02304458Phase 1/2Results posted
• Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing SarcomaActive, not recruitingNCT02243605Phase 2Results posted
• Molecular-Guided Therapy for Childhood CancerCompletedNCT02162732Not applicableResults posted
• Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid TumorsTerminatedNCT02100891Phase 2Results posted
• Eribulin Mesylate in Treating Patients With Recurrent or Refractory OsteosarcomaCompletedNCT02097238Phase 2Results posted
• SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma SubtypesCompletedNCT02048371Phase 2Results posted
• Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With CancerTerminatedNCT01987596Phase 3Results posted
• Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.CompletedNCT01987102Phase 1/2Results posted
• Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on ChemotherapyTerminatedNCT01986829Phase 2Results posted
• Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid TumorsCompletedNCT01962103Phase 1/2Results posted
• Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk OsteosarcomaTerminatedNCT01886105Phase 2Results posted
• Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma TherapyCompletedNCT01848457Phase 2Results posted
• Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in OsteosarcomaCompletedNCT01833520Phase 1/2Results posted
• Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory SarcomaCompletedNCT01614795Phase 2Results posted
• Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By SurgeryCompletedNCT01553539Phase 2Results posted
• Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue SarcomaCompletedNCT01532687Phase 2Results posted
• Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRICompletedNCT01336803Phase 2Results posted
• Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With OsteosarcomaCompletedNCT01176981Phase 3Results posted
• Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or LeukemiaCompletedNCT01154816Phase 2Results posted
• Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1/2Results posted
• Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone SarcomaCompletedNCT01016015Phase 2Results posted
• Cixutumumab in Treating Patients With Relapsed or Refractory Solid TumorsCompletedNCT00831844Phase 2Results posted
• Dacarbazine for Metastatic Soft Tissue and Bone SarcomaCompletedNCT00802880Phase 2Results posted
• A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the LungTerminatedNCT00752206Phase 2Results posted
• A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced SarcomaCompletedNCT00743509Phase 2Results posted
• Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic OsteosarcomaCompletedNCT00742924Phase 1Results posted
• Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyCompletedNCT00716976Phase 3Results posted
• Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient ChemotherapyTerminatedNCT00673179Not applicableResults posted
• A Study of Bevacizumab in Combination With Chemotherapy for Treatment of OsteosarcomaCompletedNCT00667342Phase 2Results posted
• Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without VoraxazeCompletedNCT00634504Phase 1Results posted
• High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in OsteosarcomaTerminatedNCT00634322Phase 2Results posted
• A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)TerminatedNCT00617890Phase 2Results posted
• Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed OsteosarcomaCompletedNCT00586846Phase 2Results posted
• Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone SarcomaTerminatedNCT00544778Phase 2Results posted
• Chemotherapy for Patients With OsteosarcomaCompletedNCT00523419Phase 2Results posted
• A Study of Pemetrexed in Children With Recurrent CancerCompletedNCT00520936Phase 2Results posted
• Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 3Results posted
• Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07)CompletedNCT00330421Phase 2Results posted
• Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With OsteosarcomaCompletedNCT00245011Phase 2Results posted
• Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With OsteosarcomaCompletedNCT00134030Phase 3Results posted
• Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue SarcomaCompletedNCT00112463Phase 2Results posted
• Inhalation SLIT Cisplatin (Liposomal) for the Treatment of Osteosarcoma Metastatic to the LungCompletedNCT00102531Phase 1/2Results posted
• Gemcitabine and Docetaxel in Treating Patients With Recurrent Osteosarcoma (Closed to Accrual as of 12/21/06) or Ewing's Sarcoma or Unresectable or Locally Recurrent ChondrosarcomaCompletedNCT00073983Phase 2Results posted

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