Neoplasms, Squamous Cell clinical trials
The registry lists 134 studies for Neoplasms, Squamous Cell across more than 10 countries. 14 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-18.
Status
- Completed
- 61
- Status unknown
- 27
- Terminated
- 21
- Recruiting
- 12
- Active, not recruiting
- 6
- Withdrawn
- 4
Phase
- Phase 2
- 67
- Phase 1
- 36
- Phase 3
- 10
- Early Phase 1
- 4
- Phase 4
- 1
Where
- United States
- 70
- China
- 25
- France
- 9
- Germany
- 9
- United Kingdom
- 7
- Italy
- 7
Who runs them
M.D. Anderson Cancer Center (6) · Memorial Sloan Kettering Cancer Center (6) · Peking University (5) · National Cancer Institute (NCI) (4) · Merck KGaA, Darmstadt, Germany (3) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (3) · AstraZeneca (3) · Genmab (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 134 — search for more.
- R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid TumorsRecruitingNCT06398418Phase 11 country
- Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)RecruitingNCT04198766Phase 1/24 countries
- Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)RecruitingNCT07460765Phase 11 country
- A Study of ZW251 in Participants With Advanced Solid TumorsRecruitingNCT07164313Phase 16 countries
- Neoadjuvant Radiochemotherapy Combined With Cadonilizumab for Local Advanced Esophageal Squamous Cell CancerRecruitingNCT07016724Phase 21 country
- Towards Cure Via Only Ultra-short ICB in CSCCRecruitingNCT06823479Phase 21 country
- Diagnostic Accuracy of Endocytoscopy for Superficial Esophageal NeoplasiaEnrolling by invitationNCT069840551 country
- Oral Microbiome is Associated With the Response to Chemoradiotherapy in Initial Inoperable Patients With Esophageal Squamous Cell CancerRecruitingNCT061908471 country
- Topical Ascorbic Acid for Treatment of Squamous Cell Skin CancerRecruitingNCT05932511Early Phase 11 country
- IMM2520, a PD-L1 and CD47 Bispecific Antibody in Patients With Advanced Solid TumorsRecruitingNCT05780307Phase 11 country
- Tucidinostat Plus PD-1 Inhibitor and Bevacizumab for Advanced Esophagus Cancer, AEG, Gastric CancerRecruitingNCT05163483Phase 21 country
- RFA to Prevent Metachronous Squamous Neoplasia Recurrence After Complete Endoscopic Submucosal DissectionRecruitingNCT03183115Not applicable1 country
- Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma PatientsRecruitingNCT05252078Phase 21 country
- Phase II Clinical Study of Camrelizumab Combined With Chemotherapy or Anlotinib in Advanced Esophageal Squamous Cell CancerNot yet recruitingNCT05322499Phase 21 country
- Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)Active, not recruitingNCT05797246Phase 21 country
- Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for SurgeryActive, not recruitingNCT04391049Phase 11 country
- Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT06790966Phase 31 country
- Study to Examine Lesions of the Skin Using Confocal Laser MicroscopyActive, not recruitingNCT065981371 country
- OSI-774/Cisplatin/Taxotere in Head & Neck Squamous Cell CancerCompletedNCT00076310Phase 21 country
- Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid CancersActive, not recruitingNCT03935893Phase 21 country
- Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or MelanomaCompletedNCT03336606Phase 11 country
- Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)TerminatedNCT04169074Phase 21 country
- A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1SuspendedNCT04908111Phase 1/21 country
- Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell CarcinomaCompletedNCT03370276Phase 1/21 country
- Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell CarcinomaActive, not recruitingNCT04124198Not applicable1 country
- Using MC1R Genotype to Impact Melanoma Risk BehaviorCompletedNCT03509467Not applicable2 countries
- A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other CancersCompletedNCT04180215Phase 1/23 countries
- Real-world Study of First Line Pembrolizumab- or Nivolumab-treated HPV-positive Recurrent/Metastatic Oropharyngeal Squamous Cell CarcinomaCompletedNCT067716741 country
- Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid TumorsTerminatedNCT04116320Phase 11 country
- How Consistent is the Output of DERM, When Used to Assess Images of Potentially Cancerous Skin Lesions.CompletedNCT066549991 country
- A Study of LGK974 in Patients With Malignancies Dependent on Wnt LigandsCompletedNCT01351103Phase 17 countries
- Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic UncouplingCompletedNCT02083692Early Phase 11 country
- Toripalimab with Paclitaxel and Cisplatin As Neoadjuvant Treatment for Esophageal Squamous Cell CarcinomaTerminatedNCT04804696Phase 21 country
- Examining the Risk of Skin Cancer in Multiple Sclerosis Patients Using Fingolimod: a Population-Based StudyCompletedNCT06705608
- Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and NeckCompletedNCT02113878Phase 11 country
- First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid TumoursCompletedNCT04504669Phase 14 countries
- Study of TVEC in Patients With Cutaneous Squamous Cell CancerCompletedNCT03714828Phase 21 country
- Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell CancerCompletedNCT03521570Phase 21 country
- Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell CancerCompletedNCT03667482Phase 11 country
- PF-06952229 Treatment in Adult Patients With Advanced Solid TumorsTerminatedNCT03685591Phase 11 country
- 4-Point Therapy Response Score With PET/CT for Anal Squamous Cell CancerCompletedNCT051300731 country
- LITT and Pembrolizumab in Recurrent Brain MetastasisTerminatedNCT04187872Phase 11 country
- Multimodal Monitoring of Radiotherapy Response in Squamous Cell CancerCompletedNCT023790391 country
- Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell CancerCompletedNCT01914900Phase 21 country
- Risk Factors of Relapse in Esophageal Squamous Cell Cancers Who Achieve PCR to Neoadjuvant ChemoradiotherapyActive, not recruitingNCT060612631 country
- Zalutumumab in Non-curable Patients With SCCHNCompletedNCT00542308Phase 211 countries
- Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040)CompletedNCT02252042Phase 3
- Phase II Treatment Stratification Trial Using Neck Dissection-Driven Selection to Improve Quality of Life for Low Risk Patients With HPV+ Oropharyngeal Squamous Cell CancerCompletedNCT02784288Phase 21 country
- Intended Use Study of the BD SurePath Plus™ PapTerminatedNCT012344801 country
- Primary Tumor Burden Score:A Novel Staging Parameter for ESCC After nCRTCompletedNCT05839002