Lymphohistiocytosis, Hemophagocytic: all 100 studies
Page 1 of 1. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.
- Efficacy of Short Course of Intravenous Dexamethasone and Intravenous Immunoglobulin Therapy in Infection-Related Secondary Hemophagocytic Lymphohistiocytosis (isHLH)Not yet recruitingNCT07861776Phase 3
- Establishing a National Egyptian HLH Registry (NEHR)RecruitingNCT07800234
- Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant DiseasesNot yet recruitingNCT07660783Phase 2
- All-Trans Retinoic Acid for the Treatment of Hemophagocytic LymphohistiocytosisNot yet recruitingNCT07626398Phase 2/3
- Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)RecruitingNCT07525466Phase 1/2
- Comparison of Two Etoposide Initiation Strategies for Severe Hemophagocytic LymphohistiocytosisNot yet recruitingNCT07497438Phase 3
- Prospective Single-Arm Clinical Trial of GO Regimen for HLH.RecruitingNCT07339345Phase 2/3
- Zanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell LymphomaRecruitingNCT07270835Phase 4
- Dose-modified Emapalumab and Ruxolitinib (E-Ru) Regimens for Hemophagocytic LymphohistiocytosisNot yet recruitingNCT06951971Phase 2/3
- The Microbiome in Blood Cancer and HLHNot yet recruitingNCT06734624
- Establishment of an Early Warning Screening System for Hemophagocytic Lymphohistiocytosis a Multi-center, Prospective StudyRecruitingNCT06614998
- Flow Cytometry for the Study of T-Cell Populations in Hemophagocytic Lymphohistiocytosis Associated With LymphomasRecruitingNCT06585124
- Modified DEP Regimens for the Treatment of Hemophagocytic LymphohistiocytosisNot yet recruitingNCT06504030Phase 4
- A Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCTNot yet recruitingNCT06491719Not applicable
- Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE StudyRecruitingNCT06339177
- JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care UnitNot yet recruitingNCT06244862Phase 2
- Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)RecruitingNCT06160791Phase 2
- Clinical Study of EBV-TCR-T Cells for EBV-associated Hemophagocytic Lymphohistiocytosis or EBV InfectionRecruitingNCT06135922Phase 1
- Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal InvolvementNot yet recruitingNCT06131489
- GTP Regimen in the Treatment of Refractory/Recurrent HLHNot yet recruitingNCT06038422Phase 3
- Efficacy and Safety of Carrimycin Tablets in HLH Patients With Carbapenem-resistant InfectionsNot yet recruitingNCT05988177Not applicable
- A Randomized Controlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLHRecruitingNCT05936086Not applicable
- Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic LymphohistiocytosisRecruitingNCT05898477
- Prospective Validation of the OHI IndexRecruitingNCT05882175
- Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)RecruitingNCT05762640Phase 2
- Assessing the Presence of CT-DNA in Lymphoma Associated HLHRecruitingNCT05702502
- Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLHRecruitingNCT05546060Phase 1
- Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic LymphohistiocytosisRecruitingNCT05491304Phase 4
- L-DEP/DEP Regimen and PD-1 Antibody as a Treatment for Relapse/Refractory EBV-HLHNot yet recruitingNCT05315336Phase 3
- INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)RecruitingNCT05277272
- CytOSorb TreatMent Of Critically Ill PatientS RegistryRecruitingNCT05146336
- Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RICRecruitingNCT04528355
- Prospective Cohort for Adult HemophagocytosisRecruitingNCT03117010
- Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCTRecruitingNCT01962415Phase 2
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
- Evaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic LymphohistiocytosisCompletedNCT06047210Results posted
- A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese PatientsCompletedNCT05744063Phase 4Results posted
- Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 DepletionActive, not recruitingNCT05236764Not applicableResults posted
- A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLHTerminatedNCT03985423Phase 2/3Results posted
- Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
- Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic LymphohistiocytosisCompletedNCT03312751Phase 3Results posted
- A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)CompletedNCT03311854Phase 2Results posted
- Evaluation of IFNγ and Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic LymphohistiocytosisCompletedNCT03259230Results posted
- A Pilot Study of Ruxolitinib in Secondary Hemophagocytic SyndromeCompletedNCT02400463Phase 2Results posted
- Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic LymphohistiocytosisCompletedNCT02385110Phase 2Results posted
- Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant DiseasesTerminatedNCT02231710Phase 1Results posted
- A Study for Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal AntibodyCompletedNCT02069899Phase 2/3Results posted
- Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)CompletedNCT01998633Phase 2Results posted
- Study to Investigate Safety, Efficacy of an Anti-IFNγ mAb in Children With Primary Haemophagocytic LymphohistiocytosisCompletedNCT01818492Phase 2/3Results posted
- Hybrid Immunotherapy for Hemophagocytic LymphoHistiocytosisCompletedNCT01104025Phase 2Results posted
- T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell GraftsCompletedNCT00368355Phase 2Results posted
- Stem Cell Transplant for Immunologic or Histiocytic DisordersCompletedNCT00176865Phase 2Results posted
- T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic DisordersTerminatedNCT00176826Phase 2/3Results posted
- A Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetic Characteristics, and Immunogenicity of Plonmarlimab in Subjects With Rheumatic and Immunological Disease-associated Haemophagocytic Lymphohistiocytosis (HLH) (Also Known as Macrophage Activation Syndrome (MAS))CompletedNCT07034209Phase 2
- Emapalumab Efficacy in Children With Primary Hemophagocytic LymphohistiocytosisActive, not recruitingNCT06587191
- Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH PatientsStatus unknownNCT05841342
- L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLHCompletedNCT05775705Not applicable
- Baby Detect : Genomic Newborn ScreeningCompletedNCT05687474
- Response Prediction in EBV-HLH Using Metabonomics AnalysisStatus unknownNCT05677178
- Sensitivity and Specificity of Cytokines in the Diagnosis of Lymphoma-associated HLHCompletedNCT05600959
- Clinical Study of Donor EBV-CTL Infusion in Patients With CAEBV and EBV-HLH After Allo-HSCTStatus unknownNCT05532826Not applicable
- HLH Patients - a Retrospective StudyCompletedNCT05531721
- Rituximab Monotherapy for EBV-HLH and CAEBVStatus unknownNCT05384743Phase 3
- Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male VolunteersStatus unknownNCT05353179Early Phase 1
- DEP Combine With PD-1 Antibody as an Treatment for EBV-HLHStatus unknownNCT05164978Not applicable
- Chidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLHStatus unknownNCT05137522Not applicable
- A Prospective Clinical Study of Ruxolitinib and Etoposide Combined With DDGP Regimen (RUE-DDGP) in Induction Therapy of T/NK Cell Lymphoma-associated Hemophagocytic Syndrome.Status unknownNCT04999878Phase 4
- Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and InflammationCompletedNCT04902807
- Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic LymphohistiocytosisActive, not recruitingNCT04551131Phase 1/2
- Evaluate the Efficacy and Safety of PEG-rhG-CSF in Patients With Hemophagocytic SyndromeStatus unknownNCT04500886Not applicable
- A Study of TQ05105 Tablets in Subjects With Hemophagocytic Lymphohistiocytosis（HLH）Status unknownNCT04326348Phase 1
- Ruxolitinib as a Salvage Therapy for Hemophagocytic LymphohistiocytosisStatus unknownNCT04120090Phase 3
- Pegylated Liposomal Doxorubicin as a Induction Therapy for Lymphoma Induced Hemophagocytic Lymphohistiocytosis.Status unknownNCT04077905Phase 3
- Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With CancerActive, not recruitingNCT03827343
- Ruxolitinib Combined With Dexamethasone for HLHStatus unknownNCT03795909Phase 1/2
- Etoposide in the First-line Treatment of Adult EBV-HLHStatus unknownNCT03742115Phase 3
- Early Detection of Epstein-Barr Virus Related Disease.CompletedNCT03546101
- DEP-Ru Regimen as a Salvage Therapy for HLHStatus unknownNCT03533790Phase 3
- Diagnostic Biomarkers for Adult Hemophagocytic Lymphohistiocytosis in Critically Ill Patients (HEMICU)CompletedNCT03510650
- L-DEP as an Initial Treatment for EBV-HLHStatus unknownNCT02912702Phase 3
- Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown EtiologyStatus unknownNCT02862054Phase 2/3
- Investigation of Ferritin in Critically Ill Patients With Hemophagocytic LymphohistiocytosisCompletedNCT02854943
- L-DEP Regimen as a Salvage Therapy for Refractory Epstein Barr Virus-induced Hemophagocytic LymphohistiocytosisStatus unknownNCT02631109Phase 3
- Treatment of Familiar LymphohistiocytosisCompletedNCT02472054Phase 1/2
- Children and Adult Hemophagocytic Syndrome (HLHa)CompletedNCT02113917
- Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)WithdrawnNCT02007239Phase 2
- CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell TransplantationActive, not recruitingNCT01966367Phase 1/2
- Bone Marrow Transplant With Abatacept for Non-Malignant DiseasesCompletedNCT01917708Phase 1
- Immune Disorder HSCT ProtocolActive, not recruitingNCT01821781Phase 2
- Trial of DA-EPOCH Regimen for NHL With HLHStatus unknownNCT01818908Phase 2
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesActive, not recruitingNCT01652092Not applicable
- Pilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic LymphohistiocytosisTerminatedNCT01547143Not applicable
- Administration of Donor T Cells With the Caspase-9 Suicide GeneActive, not recruitingNCT01494103Phase 1
- Secondary Adult's Hemophagocytic Lymphohistiocytosis and Innate ImmunityCompletedNCT01125319Not applicable
- New Candidate Criteria for Diagnosis of Macrophage Activation SyndromeStatus unknownNCT01095146
- CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide GeneActive, not recruitingNCT00710892Phase 1
- Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004CompletedNCT00426101Phase 3
- Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic LymphohistiocytosisStatus unknownNCT00334672Phase 3
- Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic DisordersStatus unknownNCT00006056Not applicable
- Allogeneic Bone Marrow Transplantation in Patients With Primary ImmunodeficienciesTerminatedNCT00006054Not applicable