An observational study in Hemophagocytic Lymphohistiocytoses, sponsored by Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna. Completed at 1 site in Italy. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2023-05-25.
Sponsored by Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna · Observational
Monocentric, observational, retrospective, no profit study aimed to analyze factors that are significantly impacting the outcome of patients diagnosed with HLH.
retrospective data collection to study: type of HLH familial vs secondary, sex, age, presence of infectious cause, involvement central nervous system ( SNC), hepatic involvement, presence of hemophagocytosis, presence of splenomegaly, presence of involvement of other organs, the value of neutrophils (PMN), the value of hemoglobin, platelets, albumin, triglycerides, ferritin, LDH, type of therapy and the response to therapy after 2 months
99 studies on the registry are indexed under Lymphohistiocytosis, Hemophagocytic; 36 are open to participants now.
This study's enrollment of 39 is below the median of 128 across 29 observational studies indexed under Lymphohistiocytosis, Hemophagocytic.
Browse Lymphohistiocytosis, Hemophagocytic studies →Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna is the lead sponsor of 9 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
pediatric patients with HLH
Exclusion Criteria:
pediatric patients with HLH
Other: Observation
Observation and retrospective data collection
physiological parameter that are significantly impacting the outcome of patients diagnosed with HLH
Type of HLH (familial vs secondary); sex (M or F); age (in year); presence of infectious cause; involvement central nervous system (yes or no); hepatic involvement (yes or no); presence of hemophagocytosis (yes or no); presence of splenomegaly (yes or no); involvement of other organs (yes or no); value of neutrophils (PMN, in 10\^9/L), hemoglobin (in g/dL), platelets (in 10\^9/L), albumin (in g/L), triglycerides (in mg/dL), ferritin (in UI/L) and LDH (in UI/L);
Time frame: through study completion, an average of 1 year
Plan to share: No
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This study is completed, as verified in May 2023. You cannot join it, but the record below documents what was studied.
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Lymphohistiocytosis, Hemophagocytic→
Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna